背景:我们旨在评估短期每日温度变异性(DTV)对血压正常参与者的血压(BP)的影响,高血压前期,和高血压,分别,探索不同气候带和季节的影响。
方法:涵盖亚热带的代表性人口样本(n=397,173),温带大陆,温带季风区是从中国高血压调查中获得的。DTV计算为暴露日期间每日最低和最高温度的标准偏差。线性混合效应回归模型用于估计DTV暴露与血压之间的关系。高血压前期,和高血压,分别,并按气候区和季节进行了进一步的分层分析。
结果:调整混杂因素后,在亚热带地区的高血压参与者中,暴露0~6日时DTV(2.28°C)每四分位数间距(IQR)的增加与收缩压(SBP)(SBP)和脉压(PP)0.41mmHg(95%CI:0.09,0.72)的增加相关.同样,在温带大陆地区的高血压前期参与者中,DTV暴露与SBP增加0.31mmHg(95%CI:0.06,0.55)和PP增加0.59mmHg(95%CI:0.24,0.94)相关。此外,在温暖的季节,在高血压前期和高血压人群中,DTV与SBP呈正相关,在所有三个人群中都有PP。
结论:在亚热带地区和温带大陆地区,短期DTV暴露与高血压和高血压前期参与者的SBP和PP升高相关。此外,在温暖季节有高血压前期和高血压的参与者中观察到DTV与SBP和PP呈正相关.应实施全面的健康教育和有效的干预策略,以减轻温度变化对BP的影响,特别是在高血压前期和高血压人群中。
BACKGROUND: We aimed to evaluate the impacts of short-term daily temperature variability (DTV) on blood pressure (BP) among participants with normotension, prehypertension, and hypertension, respectively, and explore the effects in different climate zones and seasons.
METHODS: A representative population sample (n = 397,173) covering the subtropical, temperate continental, and temperate monsoon zones was obtained from the China Hypertension Survey. DTV was calculated as the standard deviation of daily minimum and maximum temperatures during the exposure days. The linear mixed effect regression model was used to estimate the associations between DTV exposure and BP among normotension, prehypertension, and hypertension, respectively, and further stratified analysis was performed by climate zones and seasons.
RESULTS: After adjustment for confounders, per interquartile range (IQR) increase in DTV (2.28 °C) at 0-6 days of exposure was associated with an increase of 0.41 mmHg (95 % confidence interval [CI]: 0.07, 0.75) in systolic BP (SBP) and 0.41 mmHg (95 % CI: 0.09, 0.72) in pulse pressure (PP) among hypertensive participants in the subtropical zone. Similarly, DTV exposure was associated with an increase of 0.31 mmHg (95 % CI: 0.06, 0.55) in SBP and 0.59 mmHg (95 % CI: 0.24, 0.94) in PP among prehypertensive participants in the temperate continental zone. Additionally, during the warm season, DTV was positively associated with SBP among populations with prehypertension and hypertension, and with PP among all three populations.
CONCLUSIONS: Short-term DTV exposure was associated with an increase in SBP and PP among hypertensive and prehypertensive participants in the subtropical zone and the temperate continental zone. In addition, positive associations of DTV with SBP and PP were observed among participants with prehypertension and hypertension in the warm season. Comprehensive health education and effective intervention strategies should be implemented to mitigate the effects of temperature variations on BP, particularly among prehypertensive and hypertensive populations.