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  • 文章类型: Observational Study
    目的:研究激光辅助原位角膜磨镶术(LASIK)吸引过程中眼球的生物特征改变。
    方法:观察性和横断面研究。我们研究了43例因近视和近视散光接受手术的患者。平均年龄为38.3±11.5岁,19人为女性(44.2%)。使用手动微角膜刀进行常规LASIK手术。在抽吸操作之前和期间,使用11Mhz生物特征探头测量了以下参数:水深度(AQD),透镜厚度(LT),玻璃体腔长度(VCL)和轴向长度(AXL)。配对t检验用于比较抽吸之前和期间的生物计量测量。
    结果:平均等效球面屈光度为-4.5±2.3屈光度。抽吸期间,AQD无明显变化(p=0.231).然而,AXL和VCL分别增加0.12mm和0.22mm(p=0.039和<0.01),LT减少0.20mm(p<0.01)。AXL在42%的眼睛中增加,在16%中减少,VCL在70%的眼睛中增加,在9%中减少,67%的眼睛LT降低。
    结论:LASIK手术期间的抽吸动作在眼球中产生的变化很小,主要是LT的减少和VCL和AXL的增加。因此,这些修饰预计将产生最小的解剖改变。
    OBJECTIVE: To study the biometric modifications of the eyeball during suction in Laser assisted in Situ Keratomileusis (LASIK).
    METHODS: Observational and cross-sectional study. We studied 43 patients who underwent surgery for myopia and myopic astigmatism. Mean age was 38.3 ± 11.5 years, and 19 were female (44.2%). Conventional LASIK surgery with a manual microkeratome was performed. Before and during the suction maneuvre the following parameters were measured using an 11 Mhz biometric probe: aqueous depth (AQD), lens thickness (LT), vitreous cavity length (VCL) and axial length (AXL). Paired t-test was used to compare the biometric measurements before and during suction.
    RESULTS: The mean spherical equivalent refractive error was -4.5 ± 2.3 diopters. During suction, the AQD did not change significantly (p = 0.231). However, AXL and VCL increased by 0.12 mm and 0.22 mm respectively (p = 0.039 and <0.01) and LT decreased by 0.20 mm (p < 0.01). AXL increased in 42% of the eyes and decreased in 16%, VCL increased in 70% of the eyes and decreased in 9%, and the LT was reduced in 67% of the eyes.
    CONCLUSIONS: Suction maneuvres during LASIK surgery produce changes of little magnitude in the eye globe, mainly a decrease in LT and an increase in VCL and AXL. Therefore, these modifications are expected to produce minimal anatomic alterations.
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  • 文章类型: Journal Article
    目标:本研究报告了2021年西班牙和葡萄牙COVID-19大流行期间的视觉健康状况,专注于眼睛投诉和人群习惯。
    方法:通过在线电子邮件邀请2021年9月至11月在西班牙和葡萄牙就诊眼科诊所的患者进行横断面调查。大约3833名参与者在问卷中提供了有效的匿名回答。
    结果:60%的受访者认为,使用口罩的屏幕时间增加和镜片起雾与干眼症症状有关的不适。81.6%的参与者每天使用数字设备超过3小时,40%的参与者每天使用数字设备超过8小时。此外,44%的参与者提到近视力恶化。最常见的屈光不正是近视(40.2%)和散光(36.7%)。父母认为视力是孩子最重要的方面(87.2%)。
    结论:结果显示了初次COVID-19大流行期间眼科实践面临的挑战。关注导致眼科疾病的体征和症状是一个重要的问题,尤其是在我们高度依赖视觉的数字社会。同时,在这场大流行期间,过度使用数字设备加剧了干眼症和近视。
    OBJECTIVE: This study reports visual health during the COVID-19 pandemic in 2021 in Spain and Portugal, focusing on eye complaints and population habits.
    METHODS: Cross-sectional survey through an online email invitation to patients attending ophthalmology clinics in Spain and Portugal from September to November 2021. Around 3833 participants offered valid anonymous responses in a questionnaire.
    RESULTS: Sixty percent of respondents identified significant discomfort related to dry eye symptoms for increased screen time and lens fogging using facemasks. 81.6% of the participants used digital devices for more than 3 h per day and 40% for more than 8 h. In addition, 44% of participants referred to worsening near vision. The most frequent ametropias were myopia (40.2%) and astigmatism (36.7%). Parents considered eyesight the most important aspect of their children (87.2%).
    CONCLUSIONS: The results show the challenges for eye practices during the initial COVID-19 pandemic. Focusing on signs and symptoms that lead to ophthalmologic conditions is an essential concern, especially in our digital society highly dependent on vision. At the same time, the excessive use of digital devices during this pandemic has aggravated dry eye and myopia.
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  • 文章类型: Journal Article
    OBJECTIVE: To evaluate the stability and the refractive error of the different intraocular lens (IOL) after cataract surgery.
    METHODS: Retrospective, observational and single-center study. Patients diagnosed with cataract and myopia who underwent a phacoemulsification surgery with intraocular lens placement without complications were included. All patients underwent a complete ophthalmological examination, ultrasound biomicroscopy was performed at 2 weeks, 1 and 3 months after surgery. Descriptive statistics were performed using measures of central tendency and comparative analyzes. A value of p < 0.05 was considered significant.
    RESULTS: Thirty-one subjects with a diagnosis of axial myopia and senile cataract were included, 20 women (64.5%) and 11 men (35.5%), with a mean age was 62.8 ± 13.14 years. The IOL displacement were not different for the upper, lower, temporal and nasal quadrants; however, we observed a tendency to inclination to the temporal sector (p = 0.054) between the first and third postoperative month. Therefore, the were no significant differences in spherical equivalent between groups postoperatively.
    CONCLUSIONS: The inclination of the IOL did not change over time after surgery, the changes were similar with the different three types of IOL.
    OBJECTIVE: Evaluar la estabilidad y el desplazamiento de diferentes lentes intraoculares (LIO) a los 3 meses y los cambios refractivos asociados después de la facoemulsificación.
    UNASSIGNED: Estudio retrospectivo, observacional y unicéntrico. Se revisaron expedientes de pacientes sometidos a cirugía de facoemulsificación con colocación de LIO. Se realizó un examen oftalmológico completo, ultrabiomicroscopía a las 2 semanas, 1 y 3 meses después de la cirugía. Se realizó estadística descriptiva y análisis comparativos. Se tomó como diferencia significativa un valor de p < 0.05.
    RESULTS: Se incluyeron 31 ojos con diagnóstico de miopía y catarata senil, 20 mujeres (64.5%) y 11 hombres (35.5%), con una edad media de 62.8 ± 13.14 años. En cuanto al desplazamiento de la LIO, no se observaron diferencias significativas para los cuadrantes superior, inferior, temporal y nasal. Se observa una tendencia hacia temporal (p = 0.054) entre el primer y el tercer mes posoperatorios. El equivalente esférico tampoco mostró diferencias.
    CONCLUSIONS: El desplazamiento de la LIO no cambió con el tiempo después de la facoemulsificación. Los cambios fueron similares con los tres diferentes tipos de LIO y al compararlos proporcionan estabilidad refractiva en pacientes miopes.
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  • 文章类型: Multicenter Study
    目的:分析西班牙VisianICL有晶状体晶状体植入术的屈光手术状况,显示植入功率的平均范围,获得的视觉和屈光结果以及安全性和疗效指数。
    方法:这是基于人口的,横截面,描述性,描述性分析,回顾性,多中心研究,其中每位合著者收集了至少最后10例(最多30例)的VisianICL晶状体植入术患者的数据。从每个受试者中随机选择一只眼睛进行研究纳入。分析的变量是:年龄,性别,手术前后有或没有矫正的视力,术前和残余屈光,角膜曲率测量,内皮细胞密度,内皮前房深度,中央角膜测厚,眼内压,白色-白色,植入晶状体(功率和尺寸),手术后一个月预期和达到的球形当量(SEQ)。
    结果:从140名患者中获得140只眼的样本,平均年龄为31.35±7.28岁。术前平均SEQ为-6.33±3.69D,平均CDVA为0.96±0.16,ACD为3.30±0.29mm,WTW12.02±0.40mm,CCT535.03±37.68µm,ECD2684.37±313.74细胞/mm2和IOP14.84±2.59mmHg。植入晶状体的66.4%为球面ICL,33.6%为复曲面,平均功率为-7.81±4.09D,平均柱面为2.27±1.23D。5.7%的植入晶状体为远视晶状体。选择的平均SEQ靶标为+0.04±0.27D。48.92%的植入式晶状体尺寸为13.2mm,其余36.69、10.79和3.60%的尺寸为12.6、12.1和13.7毫米,分别。在手术后一个月,获得-0.01±0.31D的残余SEQ。疗效和安全性指数分别为1.06±0.18和1.10±0.19。平均中央拱顶为508.80±201.04µm。计算的SEQ和获得的SEQ之间的准确度对于球面透镜为99.3%,对于Cyl校正为88.2%。术后1个月的平均ECD为2805.53±273.30céls/mm2,与术前相差0.11%(p=0.922),同样,平均IOP为13.98±2.57mmHg,差异为-0.92±2.80mmHg。
    结论:ICL晶状体手术是一种有效的,安全和可预测的程序。术后1个月内皮细胞计数或眼压测量无明显变化。
    OBJECTIVE: To analyse the state of refractive surgery with Visian ICL phakic lens implantation in Spain, indicating the mean ranges of implanted powers, visual and refractive outcomes obtained and safety and efficacy indices.
    METHODS: This is a population-based, cross-sectional, descriptive, analytical, retrospective, multicentre study in which each co-author collected data from at least the last 10 patients (up to a maximum of 30) with Visian ICL phakic lens implantation. One eye from each subject was randomly selected for study inclusion, and the variables analysed were: age, gender, visual acuities with and without correction pre and post-surgery, preoperative and residualrefraction, keratometry, endothelial cellular density, anterior chamber depth from endothelium, central corneal pachymetry, intraocular pressure, white-white, implanted lens (power and size), expected and achieved spherical equivalent (SEQ) post-surgery at one month after surgery.
    RESULTS: A sample of 140 eyes was obtained from 140 patients with a mean age of 31.35 ± 7.28 years. Mean preoperative SEQ was -6.33 ± 3.69D, mean CDVA was 0.96 ± 0.16, ACD was 3.30 ± 0.29 mm, WTW 12.02 ± 0.40 mm, CCT 535.03 ± 37.68 µm, ECD 2684.37 ± 313.74 cels/mm2 and IOP 14.84 ± 2.59 mmHg. 66.4% of the implanted lenses were spherical ICLs and 33.6% toric, with a mean power of -7.81 ± 4.09D and a mean cylinder of 2.27 ± 1.23D. 5.7% of the implanted lenses were hypermetropic. The mean SEQ target selected was +0.04 ± 0.27D. 48.92% of the implanted lenses were of size 13.2 mm, with the remaining 36.69, 10.79 and 3.60% being of sizes 12.6, 12.1 and 13.7 mm, respectively. At one month after surgery a residual SEQ of -0.01 ± 0.31D was obtained. The efficacy and safety indices were 1.06 ± 0.18 and 1.10 ± 0.19, respectively. The mean central vault was 508.80 ± 201.04 µm. The accuracy between the calculated SEQ and the obtained SEQ was 99.3% for spherical lenses and 88.2% for Cyl correction. The mean ECD at 1 month after surgery was 2805.53±273.30céls/mm2, which was a difference from preoperative of 0.11% (p = 0.922), similarly, the mean IOP was 13.98 ± 2.57 mmHg, which was a difference of -0.92 ± 2.80 mmHg.
    CONCLUSIONS: ICL phakic lens surgery is an effective, safe and predictable procedure. There were no significant changes in endothelial cell count or intraocular pressure measurement one month after surgery.
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  • 文章类型: Journal Article
    目的:研究获得性共同性内斜视的手术治疗结果及其可能的原因。
    方法:对2017年以来接受手术的急性获得性内斜视患者进行回顾性研究。距离和接近水平偏差,球形当量和过度使用平板电脑和智能手机进行了分析。如果在随访结束时水平偏差≤10棱镜屈光度,则当恢复立体视觉时,认为良好的感觉结果和良好的运动结果。
    结果:共包括15例(60%为女性),平均年龄:29.07岁(86.66%≥16岁)。自手术症状开始以来的平均时间为23.3个月。术前平均水平偏差在近处为19.73±7.2pd,在远处为22.93±7.3dp,在远处为3.33±3.8pd,在远处为3.86±3.9pd(P<0.001)。66.6%的人患有diplopía。46.66%的患者患有代偿失调的内斜视或微内斜视,86,66%的近视和33.33%的人过度使用平板电脑和智能手机。内直肌衰退10例。在93.33%的病例中获得了良好的运动结果,在没有二联的情况下获得了53.3%的感觉结果。
    结论:手术是解决偏视和复视的极好治疗方法。食管和微内斜视占病例的一半左右,过度使用平板电脑和智能手机是样本的第三部分。大多数患者患有近视。
    OBJECTIVE: To study the results of surgical treatment of acquired concomitant esotropia and its posible causes.
    METHODS: Retrospective study of the patients with acute acquired esotropia that were operated on since 2017. Distance and near horizontal deviation, spherical equivalent and the excessive use of the tablets and smartphones were analyzed. A good sensorial outcome was considered when stereopsis was recovered and good motor outcome if horizontal deviation was ≤10 prism diopters at the end of the follow-up.
    RESULTS: A total of 15 cases were included (60% women), mean age: 29.07 years (86.66% ≥16 years). Mean time since the beginning of the symptoms to the surgery was 23.3 months. Mean horizontal preoperative deviation was 19.73 ± 7.2 pd at near and 22.93 ± 7.3 dp at distance decreasing to 3.33 ± 3.8 pd at near and 3.86 ± 3.9 pd at distance (P < .001). The 66.6% had diplopía. The 46.66% had decompensated esophoria or microesotropia, 86,66 % myopia and the 33.33% referred excesive use of the tablets and smartphones. The medial rectus recession were done in 10 cases. A good motor outcome was obtained in the 93.33% of the cases and sensorial outcome in the 53.3% without diplopía.
    CONCLUSIONS: Surgery was an excellent treatment to resolve the deviation and diplopia. The esophorias and microesotropias represented near the half of the cases and the excesive use of the tablets and smartphones were the third part of the sample. Most of the patients had myopia.
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  • 文章类型: Journal Article
    目的:评估近视危险因素,主要是户外接触和阅读习惯,在一个近视患病率低的国家(布宜诺斯艾利斯,阿根廷)。
    方法:在临床私人执业环境中连续接受采访的儿童在1%环戊酸钠的睫状肌麻痹下自动折射。他们的父母同意填写一份关于学校教育的问卷,辅导班,户外暴露,阅读习惯,和手机的使用,在工作日和周末。西班牙问卷基于过去的英语近视临床试验问卷。右眼的球面等效物用于屈光分布。计算每个活动每天花费的平均小时数。
    结果:这项研究涉及115名年龄为10.48±3.65岁(范围为5-18岁)的儿童,56.5%是女孩。62.6%的儿童每天接受8小时教育,只有14.8%的人在放学后上补习班。有38.3%的近视(<-0.50D),24.3%的远视眼(>+2.00D),其余为拟人化体。这些孩子每天在户外度过的平均时间为3.94±1.45h(每周27.60±10.16h)。每天平均阅读和写作总时间为1.50±0.98h,使用手机和平板电脑的时间为2.43±1.66小时。
    结论:在近视患病率较低的环境中,孩子们每天在户外度过4小时,比平时建议每天2小时预防近视。
    OBJECTIVE: To evaluate myopia risk factors, mainly outdoor exposure and reading habits, in a country with low prevalence of myopia (Buenos Aires Province, Argentina).
    METHODS: Consecutive children interviewed in a clinical private practice setting were autorefracted under cycloplegia with cyclopentolate 1%. Their parents consented to fill a questionnaire about schooling, tutorial classes, outdoor exposure, reading habits, and cellphone use, both on weekdays and weekends. The Spanish questionnaire was based on past English questionnaires of myopia clinical trials. The spherical equivalent of the right eye was used for the refractive distribution. The average daily hours spent for each activity were calculated.
    RESULTS: This study involved 115 children aged 10.48 ± 3.65 years (range 5-18 years), with 56.5% being girls. Children had 8 h of schooling per day in 62.6% of cases, and only 14.8 % had tutorial classes after school. There were 38.3% myopes (<-0.50 D), 24.3% hyperopes (>+2.00 D) and the rest were emmetropes. The mean time that these children spent outdoors per day was 3.94 ± 1.45 h (27.60 ± 10.16 h per week). The total mean time spent reading and writing per day was 1.50 ± 0.98 h, and that spent using cellphones and tablets was 2.43 ± 1.66 h.
    CONCLUSIONS: In an environment with low myopia prevalence, children spend almoast 4 h per day outdoors, much more than the usual recommendation of 2 h a day for myopia prevention.
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  • 文章类型: Journal Article
    水肺潜水可以休闲或专业地练习。在这两种模式下,潜水员都可能面临减压综合征等风险,因此,使用高压舱,气瓶的超氧,气压伤,沉浸在闭合电路中。这些情况有一些共同的现象,比如巨大的压力差异,这可能会导致广泛的改变,包括眼科的。指数近视和核性白内障的发展是经常与氧气压力升高相关的眼部发现。在这种情况下,氧化物种和抗氧化剂防御之间建立了不平衡,比如谷胱甘肽,这对保持镜头的透明度起着关键作用。病例为2名年轻的珊瑚渔民患者,他最近发展了与核性白内障相关的进行性近视。
    Scuba diving can be practiced recreationally or professionally. In both modalities the diver can be exposed to risks such as decompression syndrome and thus, the use of a hyperbaric chamber, hyper-oxygenation of the gas cylinder, barotrauma, and immersion in closed circuits. These situations have some phenomena in common, such as the great pressure differences, which can cause a wide range of alterations, including ophthalmological ones. The development of index myopia and nuclear cataract are ocular findings frequently associated with increased oxygen pressure. In this context, an imbalance is established between oxidative species and antioxidant defences, such as glutathione, which has a key role in maintaining the transparency of the lens. The cases are presented of 2 young coral fisher patients, who had recently developed a progressive myopisation associated with nuclear cataracts.
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  • 文章类型: Journal Article
    建议在为屈光不正或眼表和/或禁止角膜屈光手术的屈光手术候选人提供咨询时,建议使用晶状体人工晶状体(pIOL)。这篇综述旨在介绍目前在欧洲可用的关于pIOL模型的最新技术,解决他们的新适应症和最近的设计创新。这些包括,在后房型人工晶状体的情况下,增加了一个中心孔来改善房水循环,更大的光学区的可用性,和多焦点光学补偿老花眼。审查还强调了它们良好的安全性和有效性结果,以及患者教育的作用,以确保在中期长期的适当结果。特殊情况下PIOL的适应症,以及双晶状体切除术,大多数PIOL患者随着年龄增长和发展白内障最终可能需要的程序,也解决了。
    Phakic intraocular lenses (pIOL) are recommended when counselling refractive surgery candidates presenting with high ametropia or ocular surface and/or corneal conditions that contraindicate corneal refractive surgery. This review aims to present the state-of-the-art regarding pIOL models currently available in Europe, addressing their newer indications and recent design innovations. These include, in the case of posterior chamber pIOLs, the addition of a central hole to improve aqueous humour circulation, the availability of larger optical zones, and multifocal optics for the compensation of presbyopia. The review also highlights their good safety and efficacy results, as well as the role of patient education to ensure adequate outcomes in the medium-long term. The indications of pIOLs in special situations, as well as bi-lensectomy, a procedure that most pIOL patients may eventually require as they age and develop cataracts, are also addressed.
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  • 文章类型: Journal Article
    BACKGROUND: Body height and axial length (AL) increase during childhood with excessive axial elongation resulting in myopia. There is no consensus regarding the association between body growth and AL during refractive development. This study explored the association between change in body height, AL and refractive status over 4-years in children and young adults.
    METHODS: Measures were collected biennially (timepoints: t1, t2, t3) (t1 n = 140, aged 5-20years). Non-cycloplegic autorefraction was obtained using the Shin-Nippon openfield autorefractor. AL, corneal curvature (CC) and anterior chamber depth (ACD) were measured by IOL Master. Body height (cm) was measured using a wall mounted tape measure. Refractive status was classified using spherical equivalent refraction (SER): persistent emmetropes (PE) (-0.50D to +1.00D), persistent myopes (PM) (≤-0.50D), progressing myopes (PrM) (increase of ≤-0.50D between timepoints), incident myopes (IM) (subsequent SER≤-0.50D) and persistent hyperopes (PH) (>+1.00D).
    RESULTS: Change in AL and change in height were correlated in the PE (all t:p ≤ 0.003) and the IM (t1-t2 p = 0.04). For every increase in body height of 1 cm: t1-t2: AL increased by 0.03 mm in the PE, 0.15 in the PM, 0.11 mm in the IM, 0.14 mm in the PrM, -0.006 mm in the PH. T2-t3: AL increased by 0.02 mm in the PE, 0.06 in the PM, 0.16 mm in the PrM, 0.12 mm in the IM and -0.03 mm in the PH.
    CONCLUSIONS: In emmetropia body growth and axial elongation are correlated. In participants with myopia, body growth appears to stabilise whilst axial elongation continues at a much faster rate indicating dysregulation of normal ocular growth.
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  • 文章类型: Journal Article
    OBJECTIVE: Worldwide, the prevalence of myopia is increasing. Myopia begins at younger ages and progresses faster, leading to more adults with high myopia and risk of sight-threatening complications. No data are available about myopia trends in children in urban areas in the UK. We present a 10-year review of children attending a secondary and tertiary eye care facility in London, focussing on the proportion of glasses prescriptions for myopia and progression rates.
    METHODS: We collated refraction and demographic data from children under the age of 17 years seen at Moorfields Eye Hospital, London, UK, between 2008 and 2017.
    RESULTS: We included 63,854 datasets from 23,593 children (51.2% boys, median age 5.4 years, interquartile range IQR 3.8-7.1). The proportion of myopic prescriptions increased from 24 to 32%. In n = 3355 with initial mild/moderate myopia, median progression rate was -0.16 (-0.5 to 0.04) D/year. In those with progression (n = 2095), the rate was -0.40 (-0.19 to -0.74) D/year, slightly higher in girls than in boys (-0.42 vs -0.38 D/year; p = 0.02). Progression was faster in initial moderate than initial mild myopia (-0.54 vs -0.37 D/year; p < 0.001), and before than after average age of onset of puberty (-0.41 vs -0.35 D/year; p = 0.013). There was no statistically significant difference between children of different ethnic backgrounds.
    CONCLUSIONS: In this cohort, the proportion of glasses prescriptions for myopia and the rate of progression are higher than previously reported for European countries. Living in an urban environment may result in similar progression rates despite different genetic backgrounds.
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