Minimally invasive aortic valve surgery

  • 文章类型: Video-Audio Media
    手术机器人已被用于促进心脏手术中真正的微创方法。机器人主动脉瓣置换术可以在更广泛的解剖结构不同的患者中进行完全内窥镜检查,具有更好的可视化效果。与传统的胸骨切开术或开胸手术方法相比,它具有更快的功能恢复和优越的美容效果的潜在优势。在这个案例报告中,我们展示了机器人全内镜主动脉瓣置换术的细节。
    Surgical robots have been utilized to facilitate a truly minimally invasive approach in cardiac surgery. Robotic aortic valve replacement allows for a totally endoscopic approach with better visualization in a wider range of patients with varying anatomies. It has the potential advantages of faster functional recovery and superior cosmetic outcomes compared to traditional sternotomy or thoracotomy approaches. In this case report, we show the details of robotic totally endoscopic aortic valve replacement.
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  • 文章类型: Journal Article
    虽然与标准胸骨切开术相比,微创主动脉瓣手术的益处已被广泛描述,在微创手术中保留胸膜完整性(PPI)的影响仍被广泛讨论.本研究旨在确定PPI对微创主动脉瓣置换术(MIAVR)术后和长期结局的作用。
    在1997年至2022年间接受MIAVR(小切口或右前小切口)的所有2,430例连续患者被纳入研究。患者分为2组:有和没有PPI的患者。PPI被认为是维持胸膜闭合,而无需在外科手术结束时插入胸管。使用倾向匹配分析比较PPI组和非PPI组。
    倾向匹配后,每组848例患者(PPI和非PPI)。平均年龄为70.21岁和71.42岁,平均胸外科医师协会预测的死亡风险为0.31%,而非PPI与PPI的死亡率为0.30%,分别。平均随访时间为147.4个月。术后,非PPI与PPI患者的重症监护病房住院时间更长(9.7对17.3小时,P<0.001)和住院时间(5.2天vs8.9天,P<0.001)。呼吸系统并发症的发生率,包括气胸或皮下气肿的发生率,肺不张,非PPI患者的胸腔积液事件明显高于PPI。非PPI的30天全因死亡率高于PPI(0.029vs0.010,P=0.003)。围手术期,短期,非PPI组的长期全因死亡率显著高于对照组.
    MIAVR术后PPI与术后并发症发生率降低相关,缩短停留时间,与非PPI相比,总生存率提高。因此,MIAVR为患者量身定制的维持胸膜完整性的手术方法对短期和长期结局产生积极影响。
    UNASSIGNED: While the benefits of minimally invasive aortic valve surgery compared with standard sternotomy have been widely described, the impact of preservation of pleural integrity (PPI) in minimally invasive surgery is still widely discussed. This study aims to define the role of PPI on postoperative and long-term outcomes after minimally invasive aortic valve replacement (MIAVR).
    UNASSIGNED: All 2,430 consecutive patients undergoing MIAVR (ministernotomy or right anterior minithoracotomy) between 1997 and 2022 were included in the study. Patients were divided into 2 groups: patients with and without PPI. PPI was considered the maintenance of the pleura closed without the need for a chest tube insertion at the end of the surgical procedure. A propensity-matched analysis was used to compare the PPI and not-PPI groups.
    UNASSIGNED: After propensity matching, 848 patients were included in each group (PPI and not-PPI). The mean age was 70.21 versus 71.42 years, and the mean Society of Thoracic Surgeons predicted risk of mortality was 0.31% versus 0.30% in not-PPI versus PPI, respectively. The mean follow-up time was 147.4 months. Postoperatively, not-PPI versus PPI patients had a longer intensive care unit stay (9.7 vs 17.3 h, P < 0.001) and hospital length of stay (5.2 vs 8.9 days, P < 0.001). The rate of respiratory complications including the incidence of pneumothorax or subcutaneous emphysema, pulmonary atelectasis, and pleural effusion events requiring thoracentesis/drainage was significantly higher in not-PPI versus PPI. The 30-day all-cause mortality was higher in not-PPI versus PPI (0.029 vs 0.010, P = 0.003). Perioperative, short-term, and long-term all-cause mortality was significantly higher in the not-PPI group.
    UNASSIGNED: PPI after MIAVR is associated with reduced incidence of postoperative complications, reduced lengths of stay, and improved overall survival compared with not-PPI. Therefore, a MIAVR tailored patient-procedure approach to maintaining the pleura integrity positively impacts short-term and long-term outcomes.
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  • 文章类型: Video-Audio Media
    这项研究阐明了通过右前小切口微创主动脉瓣置换术的疗效和结果。强调它的潜力,以尽量减少手术创伤和加快恢复,同时保持程序的完整性,可与传统的全胸骨切开术。本视频教程演示了一个成功的主动脉瓣置换手术使用右前小开胸手术,其特点是缺乏无缝合的阀门和专门的仪器。详细的手术过程包括通过战略切口和肋骨脱位优化可见性和进入的具体步骤,坚持“盒子原理”有效暴露主动脉瓣。这个视频教程表明,右前微型开胸手术是可行的,具有成本效益的替代常规胸骨切开术的主动脉瓣置换术,提供显著的病人的好处,而不影响长期的阀门功能或安全。对患者选择和手术技术的更广泛影响突出了需要细致的术前计划和解剖学评估,以最大程度地发挥右前小切口在临床实践中的潜力。
    This study elucidates the efficacy and outcomes of a minimally invasive aortic valve replacement via a right anterior mini-thoracotomy, emphasizing its potential to minimize surgical trauma and expedite recovery while maintaining procedural integrity comparable to that of a traditional full sternotomy. This video tutorial demonstrates a successful aortic valve replacement procedure using the right anterior mini-thoracotomy approach, characterized by the absence of sutureless valves and specialized instruments. The detailed surgical procedure includes specific steps to optimize visibility and access through strategic incisions and rib dislocations, adhering to \"the box principle\" for effective exposure of the aortic valve. This video tutorial suggests that a right anterior mini-thoracotomy is a viable, cost-effective alternative to a conventional sternotomy for aortic valve replacement, offering significant patient benefits without compromising long-term valve function or safety. The broader implications for patient selection and surgical techniques highlight the need for meticulous preoperative planning and anatomical assessment to maximize the potential of a right anterior mini-thoracotomy in clinical practice.
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  • 文章类型: Journal Article
    主动脉瓣病变和冠状动脉疾病患者的微创和混合手术是创新的解决方案。
    报告通过右前小切口(RT-AVR)/经皮冠状动脉介入治疗(PCI)和常规主动脉瓣置换术(AVR)/冠状动脉旁路移植术(CABG)手术治疗主动脉瓣和冠状动脉疾病的结果。
    分析187例患者的前瞻性收集数据-86例混合和101例常规手术。对于21名患者,在同一会话期间,RT-AVR之后是PCI,65例患者在PCI术后90天内进行RT-AVR。
    AVR/CABG和RT-AVR/PCI组的医院死亡率分别为3.0%和1.2%,分别(p=0.237)。在RT-AVR/PCI组中,并发症发生率为18.6%,在AVR/CABG组中为33.7%(p=0.020)。由于ACS(100%),进行了两个阶段的RT-AVR/PCI;一个阶段是由于打算进行微创手术而不是AVR/CABG(71.4%)或由于缺乏CABG的血管移植物而将CABG替换为PCI(19.1%)。在两阶段亚组的38.5%的患者中,在RT-AVR之前停止抗血小板治疗,来自两阶段亚组的32.3%的患者是单,和29.2%的双重抗血小板治疗,直到RT-AVR,对术后血液需求或术后心肌梗死没有影响(分别为p=0.410和p=0.077)。
    我们系列中介绍的混合手术显示出相似的死亡率和发病率结果,并且可能是通过对某些患者进行完全胸骨切开术替代常规AVR和CABG的一种选择。
    UNASSIGNED: Minimally invasive and hybrid procedures for patients with aortic valve pathology and coronary artery disease are innovative solutions.
    UNASSIGNED: To report the results of hybrid aortic valve replacement through right anterior minithoracotomy (RT-AVR)/percutaneous coronary intervention (PCI) and conventional aortic valve replacement (AVR)/coronary artery bypass grafting (CABG) surgery for patients with aortic valve and coronary artery disease.
    UNASSIGNED: Analysis of prospectively gathered data of 187 patients - 86 hybrid and 101 conventional procedures. For 21 patients, RT-AVR was followed by PCI during the same session, and for 65 patients RT-AVR was performed within 90 days of PCI.
    UNASSIGNED: Hospital mortality in the AVR/CABG and RT-AVR/PCI groups was 3.0% and 1.2%, respectively (p = 0.237). Complications occurred in 18.6% of patients in the RT-AVR/PCI group and 33.7% in the AVR/CABG group (p = 0.020). Two-stage RT-AVR/PCI was performed due to ACS (100%); one-stage was due to the intention to perform a minimally invasive procedure instead of AVR/CABG (71.4%) or due to replacing CABG with PCI because of a lack of vascular grafts for CABG (19.1%). In 38.5% of patients from the two-stage subgroup, antiplatelet therapy was stopped before RT-AVR, 32.3% of patients from the two-stage subgroup were on single, and 29.2% on dual antiplatelet therapy until RT-AVR, which had no influence on postoperative blood requirements or postoperative myocardial infarction (p = 0.410 and p = 0.077, respectively).
    UNASSIGNED: The hybrid procedure presented in our series showed similar mortality and morbidity results and may be an alternative to conventional AVR and CABG through full sternotomy in selected patients.
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  • 文章类型: Case Reports
    右前小胸廓切开术是微创主动脉瓣手术中最不常用的方法;此外,这种通路很少用于主动脉根部手术.仔细选择病人,一些技术考虑,例如,周围体外循环的机构,和足够的学习曲线,右前小胸廓切开术可以成为主动脉根部手术干预的便捷途径。我们介绍了一例31岁的女性患者,患有Marfan综合征和由于主动脉根部动脉瘤引起的严重主动脉瓣反流。我们通过右前小胸廓切开术演示了David手术的分步指南。
    A right anterior minithoracotomy is the least-frequently utilized approach in minimally invasive aortic valve surgery; moreover, this access is rarely used for aortic root procedures. With careful patient selection, some technical considerations, e.g. institution of peripheral cardiopulmonary bypass, and a sufficient learning curve, the right anterior minithoracotomy can become a convenient access for surgical interventions on the aortic root. We present the case of a 31-year-old female patient with Marfan syndrome and severe aortic regurgitation due to an aortic root aneurysm. We demonstrate a step-by-step guide through the David procedure via a right anterior minithoracotomy.
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  • 文章类型: Journal Article
    目的:部切开术和右前小切口是微创主动脉瓣置换术的2种主要技术。这项研究的目的是比较两种技术的早期和长期结果。
    方法:前瞻性收集1999年至2019年期间接受孤立性微创主动脉瓣置换术的2419例患者的数据。回顾过去,患者分为小切口组(n=1352)和小切口组(n=1067).
    结果:在倾向得分匹配后,每组986例患者。小开胸组的手术时间和全胸骨切开术的转换率明显高于小开胸组(184.6±45.2vs241.3±68.6,相对危险度,2.54,P=0.005和.09vs.23,相对风险,1.45,P=.013)。30天死亡率,不包括心脏死亡,小切口组低于小切口组(0.012vs0.028,相对风险,1.41,P=.011);重症监护病房住院时间(12.4vs16.5,相对风险,分别为1.62,P=0.037)和住院时间(5.4vs8.7,相对风险,分别为1.74P=.028),开胸小切口组明显更长。小切口手术方法是早期死亡率最强的独立预测因子(比值比,4.24[1.67-7.35],P=.002)。通过Kaplan-Meier分析,1、3、5、10和20年的精算生存率在小切口组明显优于小切口组(P=0.0001)。5年时无再手术的精算自由度为97.3%±4.4%,小切口组为95.8%±5.2%(P=.087)。
    结论:使用小切口的微创主动脉瓣置换术与减少手术时间相关,重症监护室逗留,住院时间,术后并发症和切口疼痛,并改善早期和长期死亡率。
    Ministernotomy and right anterior minithoracotomy are the 2 main techniques applied for minimally invasive aortic valve replacement. The goal of this study is to compare early and long-term outcomes of both techniques.
    The data of 2419 patients undergoing isolated minimally invasive aortic valve replacement between 1999 and 2019 were prospectively collected. Retrospectively, patients were divided into the ministernotomy group (n = 1352) and the minithoracotomy group (n = 1067).
    After propensity score matching, 986 patients remained in each group. Operation time and rate of conversion to full sternotomy were significantly higher in the minithoracotomy group than in the ministernotomy group (184.6 ± 45.2 vs 241.3 ± 68.6, relative risk, 2.54, P = .005 and .09 vs .23, relative risk, 1.45, P = .013, respectively). The 30-day mortality, excluding cardiac death, was lower in the ministernotomy group than in the minithoracotomy group (0.012 vs 0.028, relative risk, 1.41, P = .011, respectively); the intensive care unit length of stay (12.4 vs 16.5, relative risk, 1.62, P = .037, respectively) and hospital length of stay (5.4 vs 8.7, relative risk, 1.74 P = .028, respectively) were significantly longer in the minithoracotomy group. The minithoracotomy surgical approach was the strongest independent predictor of early mortality (odds ratio, 4.24 [1.67-7.35], P = .002). The actuarial survival by Kaplan-Meier analysis at 1, 3, 5, 10, and 20 years was significantly better in the ministernotomy group than in the minithoracotomy group (P = .0001). Actuarial freedom from reoperation at 5 years was 97.3% ± 4.4% in the ministernotomy group versus 95.8% ± 5.2% in the minithoracotomy group (P = .087).
    Minimally invasive aortic valve replacement using ministernotomy is associated with reduced operative time, intensive care unit stay, hospital length of stay, and postoperative morbidities and incisional pain, and improves early and long-term mortality.
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  • 文章类型: Comparative Study
    The study objective was to compare aortic valve replacement through a right anterior minithoracotomy with aortic valve replacement through a median sternotomy.
    With propensity score matching, we selected 211 patients after aortic valve replacement through a right anterior minithoracotomy and 211 patients after aortic valve replacement who underwent operation between January 2010 and December 2013. Perioperative outcomes were analyzed, and multivariable logistic regression analysis of risk factors of postoperative morbidity was performed.
    For propensity score-matched patients, hospital mortality was 1.0% in the aortic valve replacement through a right anterior minithoracotomy group and 1.4% in the aortic valve replacement group (P = 1.000). Stroke occurred in 0.5% versus 1.4% (P = .615), myocardial infarction occurred in 1.4% versus 1.9% (P = 1.000), and new onset of atrial fibrillation occurred in 12.8% versus 24.2% (P = .003) of patients in the aortic valve replacement through a right anterior minithoracotomy and aortic valve replacement groups, respectively. Postoperative drainage was 353.5 ± 248.6 mL versus 544.3 ± 324.5 mL (P < .001) and blood transfusion was required for 48.8% versus 67.3% (P < .001) of patients in the aortic valve replacement through a right anterior minithoracotomy and aortic valve replacement groups, respectively. Mediastinitis occurred in 2.8% of patients after aortic valve replacement and in 0.0% of patients after aortic valve replacement through a right anterior minithoracotomy surgery (P = .040). Intensive care unit stay (1.3 ± 1.2 days vs 2.6 ± 2.6 days) and hospital stay (5.7 ± 1.6 days vs 8.7 ± 4.4 days) were statistically significantly shorter in the aortic valve replacement through a right anterior minithoracotomy group. Aortic valve replacement through a right anterior minithoracotomy surgery resulted in reduced postoperative morbidity (odds ratio, 0.4; P < .001) and postoperative bleeding and blood transfusion requirements (odds ratio, 0.4; P < .001).
    Aortic valve replacement through a right anterior minithoracotomy surgery resulted in a reduced infection rate, diminished postoperative bleeding and blood transfusion requirements, reduced occurrence of new onset of atrial fibrillation, and shorter intensive care unit and hospital stays.
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  • 文章类型: Journal Article
    OBJECTIVE: To compare the function of the respiratory system after aortic valve replacement through median sternotomy (AVR) or the minimally invasive right anterior minithoracotomy (RAT-AVR) approach among elderly (aged≥75 years) patients.
    METHODS: Observational cohort study.
    METHODS: University hospital.
    METHODS: The study included 65 elderly patients scheduled for RAT-AVR and 82 for standard AVR.
    METHODS: Pulmonary function tests (PFT) were performed preoperatively, 1 week, 1 month, and 3 months after surgery. In addition, respiratory complications were analyzed.
    RESULTS: Respiratory complications occurred in 12.3% of patients in the RAT-AVR group and 18.3% of patients in the AVR group (p = 0.445). Mechanical ventilation time in the intensive care unit was 7.7±3.6 hours for RAT-AVR patients and 9.7±5.4 hours for AVR patients (p = 0.003). Most PFT were worse in the AVR group than in the RAT-AVR group when performed 1 week after surgery. After 1 month, forced expiratory volume in the first second, vital capacity, and total lung capacity differed significantly in favor of the RAT-AVR group (p = 0.002, p<0.001, and p = 0.001, respectively). After 3 months, the PFT parameters still had not returned to preoperative values, but the differences were no longer significant between the RAT-AVR and AVR groups. The multivariable median regression analysis demonstrated that RAT-AVR surgery was a key factor in a patient\'s higher postoperative PFT parameter values.
    CONCLUSIONS: RAT-AVR surgery resulted in shorter postoperative mechanical ventilation time and improved the recovery of pulmonary function in elderly patients, but it did not reduce the incidence of pulmonary complications when compared with surgery performed through a median sternotomy.
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  • 文章类型: Journal Article
    During the past 50 years, median sternotomy has been the gold standard approach in cardiac surgery with excellent long-term outcomes. However, since the 1990 s, minimally invasive cardiac surgery (MICS) has gained wide acceptance due to patient and economic demand. The advantages include less surgical trauma, less bleeding, less wound infections, less pain and faster recovery of the patients. One of these MICS approaches is the J-shaped upper ministernotomy which results in favourable long-term outcomes even in elderly and redo patients when compared with conventional sternotomy. Owing to its similarity to a full midline sternotomy, it has become the most popular MICS approach besides a mini-thoracotomy. It is a safe and feasible access, but certain recognized principles are mandatory to minimize complications. After identification of the landmarks, the 5-cm skin incision is performed in the midline between the second and fourth rib. The third or fourth right intercostal space is located and dissected laterally off the sternum. After osteotomy, the pericardium is pulled up with stay sutures which allow excellent exposure. The surgical procedures are performed in a standard fashion with central cannulation. Continuous CO2 insufflation is used to minimize the risk of air embolism. Epicardial pacing wires are placed before the removal of the aortic cross-clamp and one chest tube is used. Sternal closure is achieved with three to five stainless steel wires. The pectoral muscle, subcutaneous tissue and skin are adapted with resorbable running sutures. When performed properly, complications are rare (conversion, bleeding and wound infection) and well manageable.
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  • 文章类型: Journal Article
    Minimally invasive aortic valve replacement (MIAVR) is associated with numerous advantages including improved patient satisfaction, cosmesis, decreased transfusion requirements, and cost-effectiveness. Despite these advantages, little information exists on how to build a MIAVR program from the ground up. The steps to build a MIAVR program include compiling a multi-disciplinary team composed of surgeons, cardiologists, anesthesiologists, perfusionists, operating room (OR) technicians, and nurses. Once assembled, this team can then approach hospital administrators to present a cost-benefit analysis of MIAVR, emphasizing the importance of reduced resource utilization in the long-term to offset the initial financial investment that will be required. With hospital approval, training can commence to provide surgeons and other staff with the necessary knowledge and skills in MIAVR procedures and outcomes. Marketing and advertising of the program through the use of social media, educational conferences, grand rounds, and printed media will attract the initial patients. A dedicated website for the program can function as a \"virtual lobby\" for patients wanting to learn more. Initially, conservative selection criteria of cases that qualify for MIAVR will set the program up for success by avoiding complex co-morbidities and surgical techniques. During the learning curve phase of the program, patient safety should be a priority.
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