Miners

矿工
  • 文章类型: Journal Article
    促进健康的行为对矿工的整体健康和福祉具有重要意义。这项研究旨在研究累积风险(CR)与矿工健康促进行为之间的关系,并测试健康信念在这种关系中的中介作用。
    数据来自对中国712名前线矿工(Mage=41.7±10.1岁)进行的连续调查。这项调查需要在三个不同的时间点进行在线问卷调查测量,每个间隔两周。本研究利用健康促进行为的概念模型,CR模型,关系分析中的结构方程模型。
    CR与健康促进行为呈负相关,具有负加速效应。CR在梯度效应中与感知到的威胁呈正相关,而与梯度效应中的感知益处负相关。此外,CR与自我效能感呈负相关,负加速效应之后。感知到的威胁,感知到的好处,自我效能感在CR与健康促进行为之间的关系中成为重要的中介。
    这项研究强调了考虑CR和健康信念在塑造矿工健康促进行为方面的关键作用。了解这些动态对于制定干预措施以增强矿工的健康和福祉至关重要。
    UNASSIGNED: Health-promoting behaviors carry substantial significance for miners\' overall health and well-being. This study aimed to examine the association between cumulative risk (CR) and miners\' health-promoting behaviors and test the mediating role of health beliefs in this relationship.
    UNASSIGNED: Data were collected from a sequential survey conducted among 712 frontline miners (Mage=41.7 ± 10.1 years) in China. The survey entailed online questionnaire measurements at three distinct time points, each spaced two weeks apart. This study utilized the conceptual model of health-promoting behaviors, the CR model, and structural equation modeling in the analysis of relationships.
    UNASSIGNED: CR was negatively related to health-promoting behaviors, with a negative acceleration effect. CR was positively associated with perceived threat in a gradient effect, while negatively associated with perceived benefits in a gradient effect. Furthermore, CR was negatively related to self-efficacy, following a negative acceleration effect. Perceived threat, perceived benefits, and self-efficacy emerged as significant mediators in the relationship between CR and health-promoting behaviors.
    UNASSIGNED: This study highlights the critical role of considering both CR and health beliefs in shaping miners\' health-promoting behaviors. Understanding these dynamics is pivotal for developing interventions to enhance miners\' health and well-being.
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  • 文章类型: Journal Article
    在矿山非法工作的金矿矿工生活在恶劣的健康状况中,这与他们艰苦的工作和不稳定的住房有关。因此,他们患传染病的风险更高。居住在圭亚那盾牌地区的人口似乎非常关注美国的利什曼病(ATL)。我们的目的是描述他们的人口特征,皮肤利什曼病(CL)的临床特征,以及在法属圭亚那非法金矿工作的人感染利什曼原虫的频率。2019年10月至12月在Oiapoque市进行了一项横断面研究,阿马帕,巴西。的确,许多在法属圭亚那工作的金矿工人最初来自巴西,尤其是Oiapoque.总共招募了来自法属圭亚那31个不同采矿地点的105名参与者。通过以下方法证实了可疑的利什曼原虫感染:检测血液或病变部位的kDNA;检测特异性抗体;或检测血液与利什曼虫抗原(IGRA-Leish)孵育后的IFN-γ释放。9例活动性CL,38例治愈的ATL(hATL)和58例无ATL(noATL)病史,已确定。据报道,只有一半的接受治疗的hATL(50.0%;n=14)得到了卫生保健单位的帮助,其他人则自行治疗。在100%的CL病例的血液中,利什曼原虫的PCR-kDNA呈阳性。奇怪的是,13%的hATL患者和15.5%的noATL患者的血液PCR-kDNA阳性.IGRA-Leish在60.5%的hATL和37.9%的noATL中呈阳性。除了暗示CL的疤痕,71%的hATL有利什曼原虫感染的实验室证据。hsp70基因的限制性片段多态性(RFLP)鉴定了L.(V.)古人类(n=4),L.(五.)巴西(n=1),L.(L.)亚马逊(n=2),L.(五.)沙维(n=1)和L.(V.)奈菲/沙维(n=1)。将实验室技术和临床评估结合起来,105名参与者中有76%(n=80)有利什曼原虫感染的证据。这些结果表明,在法属圭亚那工作的非法金矿工人感染不同种类的利什曼原虫的风险很高,但是他们的非法状况和偏远使他们难以获得医疗服务。
    Gold miners working illegally in mines live in poor health conditions related to their strenuous work and precarious housing. Therefore, they are at higher risk for infectious diseases. American tegumentary leishmaniasis (ATL) appears to be of great concern to the population living in the Guiana Shield region. Our aim was to describe their demographic characteristics, the clinical features of cutaneous leishmaniasis (CL), and the frequency of Leishmania infection in people working in illegal gold mines in French Guiana. A cross-sectional study was carried out from October to December 2019 in Oiapoque city, Amapá, Brazil. Indeed, many gold miners working in French Guiana are originally from Brazil, and from Oiapoque in particular. A total of 105 participants from 31 different mining sites in French Guiana were recruited. Suspected Leishmania infection was confirmed by the following: detection of kDNA in blood or the lesion site; detection of specific antibodies; or detection of IFN-γ release after blood incubation with leishmanial antigens (IGRA-Leish). Nine active CL cases, 38 healed ATL (hATL) and 58 cases with no history of ATL (noATL), were identified. Only half of the treated hATL (50.0%; n = 14) reported having been assisted by a health care unit and the others treated themselves. PCR-kDNA for Leishmania was positive in the blood of 100% of CL cases. Curiously, blood PCR-kDNA was positive in 13% of hATL patients and in 15.5% of noATL patients. The IGRA-Leish was positive in 60.5% of hATL and in 37.9% of noATL. In addition to scars suggestive of CL, 71% of hATL had laboratory evidence of Leishmania infection. Restriction fragment polymorphism (RFLP) of the hsp70 gene identified a sympatric circulation of L. (V.) guyanensis (n = 4), L. (V.) braziliensis (n = 1), L. (L.) amazonensis (n = 2), L. (V.) shawi (n = 1) and L. (V.) naiffi/shawi (n = 1). Taking the laboratory techniques and the clinical evaluations together, 76% (n = 80) of the 105 participants had evidence of Leishmania infection. These results suggests that illegal gold miners working in French Guiana are at high risk for infection with different species of Leishmania, but their illegal condition and remoteness make it difficult for them to access health services.
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  • 文章类型: Journal Article
    本系列病例揭示了春雅区个体金矿工人的肺部疾病,姆贝亚,坦桑尼亚。我们提供了来自21名矿工的3个案例。病人,年龄和采矿暴露,表现出严重肺部疾病的症状,包括尘肺,肺动脉高压和肺心病,归因于长时间暴露于粉尘和采矿环境中保护措施不足。这些案件突出表明,迫切需要在手工采矿社区提高职业卫生标准和预防战略。
    This case series sheds light on the pulmonary diseases afflicting artisanal gold miners in Chunya district, Mbeya, Tanzania. We present 3 cases from a group of 21 miners. The patients, ranging in age and mining exposure, exhibited symptoms of severe pulmonary conditions, including pneumoconiosis, pulmonary hypertension and Cor pulmonale, attributed to prolonged exposure to dust and inadequate protective measures in mining environments. These cases underscore the urgent need for enhanced occupational health standards and preventive strategies in artisanal mining communities.
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  • 文章类型: Journal Article
    背景:工作场所的健康危害仍然是采矿业工人的重要问题,矿工不断接触各种暴露源。
    方法:首先,矿工健康的决定因素是从259份出版物中系统地提取的,包括化学品,物理,符合人体工程学,和心理社会压力源,脆弱性因素,和共同的健康结果。然后,进行了16项荟萃分析,以确定四种压力源与三种健康结果之间关联的流行病学证据。通过166项可用的前瞻性研究,确定了影响矿工健康的七个主要因素。最后,基于经典和国内的测量尺度,我们对559名中国矿工进行了横断面调查,以确定核心心理社会预测因子。除了传统机制,还获得了前因后果之间的复杂交互网络和后果的反向效应,其中,通过Apriori算法产生了379条强关联规则。
    结果:结果表明,职业性粉尘,NO2,重金属,热,振动,尴尬的姿势,和工作压力是与个人健康状况相关的重要风险因素。心理资本,应对方式,工作需求,社会支持,组织支持,正义,和文化是矿工的核心心理社会预测因子。
    结论:本研究提供了一个案例,用于确定与个人健康相关的最重要的职业危险因素,可以扩展并应用于其他行业,随着世界各地的劳动人口遭受各种化学物质的折磨,物理,符合人体工程学,和心理社会压力源。
    结论:确定影响工人健康状况的重要职业危险因素对于全面的职业健康风险评估和管理至关重要。因此,这项研究对矿山和其他行业的健康管理可能很重要。
    BACKGROUND: The workplace\'s health hazard remains a significant concern to workers in the mining industry, where miners are continually exposed to various kinds of exposure sources.
    METHODS: First, the determinants of miners\' health were systematically extracted from 259 publications, comprising chemical, physical, ergonomic, and psychosocial stressors, vulnerability factors, and common health outcomes. Then, 16 meta-analyses were performed to ascertain the epidemiological evidence for associations between four stressors and three health outcomes. The seven top contributing factors affecting miners\' health were identified through 166 available prospective studies. Finally, based on the classic and domestic measurement scales, a cross-sectional survey of 559 Chinese miners was conducted to determine the core psychosocial predictors. In addition to the traditional mechanisms, complex interactive networks among the antecedents and consequences and the reversed effects of consequences were also obtained, where 379 strong association rules were yielded via the Apriori algorithm.
    RESULTS: The results showed that occupational dust, NO2, heavy metals, heat, vibration, awkward posture, and job stress are significant risk factors associated with individuals\' health conditions. Psychological capital, coping style, job demand, social support, organizational support, justice, and culture are core psychosocial predictors of miners.
    CONCLUSIONS: This study presents a case for identifying the most significant occupational risk factors related to individuals\' health, which could be extended and applied to other industries, as working populations around the world are suffering from various chemical, physical, ergonomic, and psychosocial stressors.
    CONCLUSIONS: Identifying the significant occupational risk factors affecting workers\' health conditions is essential for comprehensive occupational health risk assessment and management. Therefore, this study could be important for health management in mines and other industries.
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  • 文章类型: Journal Article
    In order to clarify the transmission mechanism of the impact of mechanization on the occupational health of miners and to provide empirical evidence for the development of new quality productivity in the coal industry that balances health and efficiency. In August 2022, we selected a typical coal mine, constructed a comprehensive evaluation index of miners\' occupational health through a questionnaire survey based on the fully connected neural network model. A Bayesian model was used to verify the influence of mechanization level on miners\' occupational health. We found that: the predicted probability of occupational diseases could be used as a comprehensive indicator of the level of occupational health, providing a basis for early intervention and prevention of occupational diseases. Mechanization could directly promote the improvement of miners\' occupational health level, and also indirectly affect occupational health level by influencing hazards level and work intensity. The indirect effect of mechanization on work intensity was positive, and the indirect effect of mechanization on hazards level was positive. Presented the \"inverted U-shaped\" process in the mechanization breakthrough semi-mechanized level would realize the economies of scale of health protection, its impact on the prevention and control of occupational hazards would turn from negative to positive.
    探索机械化对矿工职业健康影响的传导机制,为煤炭行业发展健康与高效兼顾的新质生产力提供实证依据,于2022年8月,选择某典型煤矿,通过问卷调查,基于全连接神经网络模型,构建矿工职业健康综合评价指标,并采用贝叶斯模型验证机械化水平对矿工职业健康的影响。研究发现,职业病预测概率可以作为职业健康水平的综合指标,为职业病的早期干预与预防提供依据;机械化水平可以直接促进矿工职业健康水平的提升,也可以通过影响危害因素水平和工作强度来间接影响职业健康水平;机械化水平对工作强度的间接影响是正向的,机械化水平对危害因素水平的间接影响呈现出的\"倒U型\"过程,在机械化水平突破半机械化水平后会实现健康防护的规模经济效应,其对职业危害因素防控的影响会由负转正。.
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  • 文章类型: Journal Article
    随着煤炭开采深度的增加,地下环境的温度和湿度也升高,这会对矿工的生理健康产生负面影响,甚至可能对他们的安全和生命构成威胁。然而,关于温度之间关系的神经认知机制的研究,湿度,湿度矿工的警觉性不足。本研究考察了几个研究目标:(A)不同温度和湿度条件下反应时间和错误率的差异,哪个因素影响较大;(B)不同条件下Oxy-Hb水平的差异以及哪个因素影响较大;(C)不同感兴趣区域之间激活程度的差异;(D)不同条件下不同感兴趣区域之间Oxy-Hb时间过程的形状差异。在这项研究中,fNIRS用于测量100名参与者的前额叶皮层的活动。结果表明,温度和湿度都会导致矿工警觉性下降,这不仅会延长反应时间,增加错误率,并增加Oxy-Hb浓度,但也导致前额叶皮层的激活增加,右侧的激活比左侧的激活更大,Oxy-Hb的时间过程是不同的双方,温度比湿度对警觉性的影响更大。
    As the depth of coal mining increases, the temperature and humidity of the underground environment also rise, which can negatively impact the physiological health of miners, and may even pose a threat to their safety and lives. However, studies on the neurocognitive mechanisms underlying the relationship between temperature, humidity, and miners\' alertness are scant. This study investigates several research objectives: (A) the differences in reaction time and error rate in different temperature and humidity conditions, which factor has a greater impact; (B) the differences in the levels of Oxy-Hb in different conditions and which factor has a greater impact; (C) the differences of activation degree between different regions of interest; and (D) the differences in the shape of Oxy-Hb time course between different conditions between different regions of interests. The fNIRS was used to measure the activity in 100 participants\' prefrontal cortex in this study. The results showed that both temperature and humidity would lead to decreased alertness of miners, which would not only prolong the reaction time, increase the error rate, and increase the Oxy-Hb concentration, but also lead to increased activation of the prefrontal cortex and greater activation of the right side than that of the left side, the Oxy-Hb time course was different on both sides, and temperature has a greater effect on alertness than humidity.
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  • 文章类型: Journal Article
    背景:世界卫生组织建议对接触二氧化硅的工人进行系统的胸部X射线(CXR)筛查结核病(TB)。然而,缺乏在此类人群中进行CXR筛查的准确性的证据.
    目的:为了测量暴露于二氧化硅的矿工中CXR筛查活动性结核病的准确性,在矽肺病患病率较高的人群中,结核病后肺病和艾滋病毒。
    方法:对莱索托矿工筛查计划的数据进行了二次分析。我们测量了CXR(在有咳嗽和无咳嗽的参与者中)对XpertMTB/RIF(Xpert)的“提示TB异常”的表现。样本量为2572,阳性Xpert患病率为3%。
    结果:单独的CXR具有很高的灵敏度(0.93,95%置信区间[CI]0.87-0.99),但特异性低(0.41,95%CI0.39-0.42)。需要咳嗽和CXR阳性增加特异性(0.79,95%CI0.77-0.81),导致灵敏度降低(0.41,95%CI0.30-0.52)。不同HIV状况的CXR准确性没有差异。然而,在存在矽肺病(从0.70,95%CI0.68-0.72到0.03,95%CI0.02-0.04)或既往TB病史(从0.59,95%CI0.56-0.62到0.27,95%CI0.25-0.29)时,特异性显著降低.在整个过程中,阳性预测值仍然很低(5%),阴性预测值非常高(99%)。
    结论:CXR筛查可准确识别该人群中的TB阴性CXR,但结核病后肺部疾病和矽肺将导致Xpert阴性转诊比例高,并增加不必要的经验性治疗的风险.适应的筛选算法,需要从业人员培训和对以前的采矿CXR的数字访问。
    The World Health Organization recommends systematic chest X-ray (CXR) screening for tuberculosis (TB) in silica-exposed workers. However, evidence on the accuracy of CXR screening in such populations is lacking.
    To measure the accuracy of CXR screening for active TB in silica-exposed miners, in a population with a high prevalence of silicosis, post-TB lung disease and HIV.
    A secondary analysis of data from a miner screening programme in Lesotho was undertaken. We measured the performance of CXR (in participants with and without cough) for \'abnormalities suggestive of TB\' against Xpert MTB/RIF (Xpert). The sample size was 2572 and positive Xpert prevalence was 3%.
    CXR alone had high sensitivity (0.93, 95% confidence interval [CI] 0.87-0.99), but low specificity (0.41, 95% CI 0.39-0.42). Requiring cough and a positive CXR increased specificity (0.79, 95% CI 0.77-0.81), resulting in reduced sensitivity (0.41, 95% CI 0.30-0.52). There was no difference in CXR accuracy by HIV status. However, specificity was markedly reduced in the presence of silicosis (from 0.70, 95% CI 0.68-0.72, to 0.03, 95% CI 0.02-0.04) or past TB history (from 0.59, 95% CI 0.56-0.62 to 0.27, 95% CI 0.25-0.29). Throughout, positive predictive value remained very low (5%) and negative predictive value very high (99%).
    CXR screening accurately identifies TB-negative CXRs in this population, but post-TB lung disease and silicosis would result in a high proportion of Xpert-negative referrals and an increased risk of unneeded empirical treatment. Adapted screening algorithms, practitioner training and digital access to previous mining CXRs are needed.
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  • 文章类型: Journal Article
    1933年开始在圣劳伦斯纽芬兰进行萤石的商业开采。在地下工作的矿工暴露于高水平的氡子体,特别是在1960年通风被引入矿井之前。该队列中地下矿工的平均累积氡暴露为380.9工作水平月(WLM)。该队列的一系列研究已经表征了由于氡导致的肺癌死亡风险增加。我们将这一队列的随访期延长了15年,以提供有关低水平氡暴露风险的更多见解,以及曝光后时间的修正效应,初次接触时的年龄,年龄,暴露的持续时间,和吸烟。该队列由1,735名地下矿工和315名男性地面矿工组成,合并,应计81,650人年随访。该队列的死亡率经验是通过与加拿大国家死亡数据的记录联系从1950年至2016年确定的。暴露于氡子体的个体水平估计,在WLM中,是为就业的每一年确定的。我们使用标准化死亡率(SMR)将地下矿工的死亡率经验与纽芬兰男子进行了比较。泊松回归模型被拟合以估计每100WLM的超额相对风险(ERR)。确认了236例肺癌死亡病例,其中,221发生在地下工人中。与纽芬兰男性相比,地下矿工肺癌的SMR为2.67(95%CI:2.33,3.04)。每100WLM肺癌死亡率的ERR,假设暴露滞后5年,为0.41(95%CI:0.23,0.59)。自从暴露以来达到的年龄和时间是氡与肺癌关系的重要调节剂。吸烟和氡对肺癌风险的联合关系是亚累加的,然而,吸烟数据有限,仅有一半的队列可用.
    The commercial mining of fluorspar in St. Lawrence Newfoundland began in 1933. Miners who worked underground were exposed to high levels of radon progeny, especially before ventilation was introduced into the mines in 1960. The mean cumulative radon exposure for underground miners in this cohort was 380.9 working level months (WLM). A series of studies of this cohort have characterized the increased risks of lung cancer mortality due to radon. We have extended the follow-up of this cohort an additional 15 years to provide additional insights on the risks of low levels of radon exposure, and the modifying effects of time since exposure, age at first exposure, attained age, duration of exposure, and cigarette smoking. The cohort consisted of 1,735 underground and 315 male surface miners who, combined, accrued 81,650 person-years of follow-up. The mortality experience of the cohort was determined from 1950-2016 through record linkage to Canadian national death data. Individual-level estimates of exposure to radon progeny, in WLMs, were determined for each year of employment. We compared the mortality experience of the underground miners to Newfoundland men using the standardized mortality ratio (SMR). Poisson regression models were fit to estimate excess relative risks (ERR) per 100 WLM. There were 236 lung cancer deaths identified, and of these, 221 occurred among underground workers. The SMR for lung cancer among underground miners compared to Newfoundland men was 2.67 (95% CI: 2.33, 3.04). The ERR per 100 WLM for lung cancer mortality, assuming a 5-year exposure lag, was 0.41 (95% CI: 0.23, 0.59). Attained age and time since exposure were important modifiers to the radon-lung cancer relationship. The joint relationship between smoking and radon on lung cancer risk was sub-additive, however, the smoking data were limited and available for only half of the cohort.
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  • 文章类型: Journal Article
    金价上涨导致手工和小规模金矿开采(ASGM)业务在撒哈拉以南非洲激增,延伸到农业领域。在这些新领域,对农业和采矿之间的相互作用知之甚少。本研究旨在调查ASGM对自然和物质生计资本的影响,ASGM与家庭农业的互动,社区和机构层面以及支撑这些互动的驱动因素,以及对可持续农业和ASGM共存的政策影响。除了文献综述,在Atiwa西区和Koferidua进行了野外工作,加纳使用环境实地调查,问卷,焦点小组讨论和访谈。问卷和实地调查数据采用描述性统计分析,对访谈和焦点小组数据进行主题分析。调查结果显示,大多数矿工不受监管,不负责任地开采退化的土地,水路,和农场道路。超过三分之一的农民(38%)遭受土地退化,79%的受影响农民的土地没有被开垦。农民多元化进入ASGM,采矿收益促进了农业发展。年轻的农民(18-40岁)转向ASGM全职工作,因为它更有利可图。然而,ASGM并没有取代农业:可可种植仍然是一项重要的经济活动。非正式的ASGM在家庭层面为一些人创造短期收入,但在社区层面强加长期成本,与农业用地的累积损失以及森林面积和水体的退化有关,制造紧张局势,和增加的脆弱性。农民面临的经济困难,地主希望直接从黄金中受益,缺乏执法推动了非正式的ASGM。农业和采矿部门之间没有机构联系。需要在农业和采矿业以及正式和非正式(传统)机构之间进行更多的联合治理。ASGM应纳入更广泛的农村发展政策改革,以支持农民,激励矿工合法和负责任地运营,并确保有效的利益相关者参与。
    Rising gold prices have led artisanal and small-scale gold mining (ASGM) operations to proliferate in sub-Saharan Africa, extending into agricultural areas. Little is known about the interactions between agriculture and mining in these new frontiers. This study aimed to investigate the impacts of ASGM on natural and physical livelihood capitals, ASGM\'s interactions with agriculture at household, community and institutional levels and the drivers underpinning those interactions, and the policy implications for the co-existence of sustainable agriculture and ASGM. Alongside literature review, field-work took place in Atiwa West District and Koforidua, Ghana using environmental field surveys, questionnaires, focus group discussions and interviews. Questionnaire and field survey data were analysed using descriptive statistics, with thematic analysis of interviews and focus group data. Findings revealed that most miners were unregulated, mined irresponsibly and degraded land, waterways, and farm roads. Over one-third of farmers (38%) suffered land degradation, and 79% of affected farmers\' lands were not reclaimed. Farmers diversified into ASGM, and mining proceeds boosted farming. Young farmers (18-40 years) shifted into ASGM full-time because it is more lucrative. Yet, ASGM is not replacing agriculture: cocoa farming remains a vital economic activity. Informal ASGM generates short-term income at household level for some but imposes long-term costs at community level, linked to cumulative loss of agricultural land and degradation of forest areas and water bodies, creating tensions, and increasing vulnerability. Financial hardships faced by farmers, landowners\' desire to benefit directly from gold and lack of law enforcement drive informal ASGM. There are no institutional linkages between the agricultural and mining sectors. More joined up governance across agriculture and mining is needed and between formal and informal (traditional) institutions. ASGM should be incorporated into broader rural development policy reforms that support farmers, incentivise miners to operate legally and responsibly and ensure effective stakeholder engagement.
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  • 文章类型: Journal Article
    汞是一种剧毒的重金属,可能会导致神经系统,呼吸,胃肠道和皮肤病。先前描述的汞毒性的神经系统表现是对称的,包括小脑前病变综合征,全身性癫痫和脑病。汞用于黄金开采过程,在手工或非法金矿开采中,往往没有必要的保护。在这里,我们描述了两个来自约翰内斯堡西部的手工金矿开采者的案例,南非,表现为汞毒性的非典型神经系统表现。患者1出现局灶性癫痫发作,不对称小脑综合征和急性脑病。患者2患有单侧小脑共济失调。两个病人都有有毒的汞含量,没有其他原因确定他们的症状。患者1对螯合疗法反应良好,但患者2拒绝入院和进一步治疗.汞中毒的神经表现通常是对称的,而我们的两名患者表现出明显的不对称特征。重要的是要保持对汞中毒的高怀疑指数,即使是非典型和单侧或不对称表现的患者。及时诊断和早期螯合治疗的开始有可能产生良好的结果。
    Mercury is a highly toxic heavy metal that may cause neurological, respiratory, gastrointestinal and dermatological illnesses. Previously described neurological manifestations of mercury toxicity are symmetrical, and include a pancerebellar syndrome, generalised seizures and encephalopathy. Mercury is used in the gold mining process, and in artisanal or illicit gold mining, often without necessary protection. Here we describe the cases of two artisanal gold miners from western Johannesburg, South Africa, who presented with atypical neurological manifestations of mercury toxicity. Patient 1 presented with focal seizures, an asymmetrical cerebellar syndrome and an acute encephalopathy. Patient 2 had unilateral cerebellar ataxia. Both patients had toxic mercury levels, with no other cause identified for their symptoms. Patient 1 responded well to chelation therapy, but patient 2 refused admission and further medical treatment. The neurological manifestations of mercury toxicity are typically symmetrical, whereas our two patients presented with markedly asymmetrical features. It is important to maintain a high index of suspicion for mercury poisoning, even in patients with atypical and unilateral or asymmetrical presentations. A prompt diagnosis and the commencement of early chelation therapy have the potential to produce good outcomes.
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