氯化石蜡(CPs),一组具有不同碳链长度和氯含量的混合物,在各种室内材料中广泛用作增塑剂和阻燃剂。CP可以从含CP的材料中释放到周围环境中,然后通过吸入进入人体。粉尘摄入和皮肤吸收,对人类健康产生潜在影响。在这项研究中,我们收集了武汉的住宅室内灰尘,中国中部最大的城市,并重点关注CP的共同发生和组成概况以及通过粉尘摄入和皮肤吸收导致的人类风险。结果表明,具有C9-40的CPs在具有中链CPs的室内粉尘中普遍存在(MCCPs,C14-17)为主要成分(6.70-495μgg-1),其次是短链CP(短链氯化石蜡,C10-13)(4.23-304μgg-1)和长链(LCCPs,C≥18)CPs(3.68-331μgg-1)。低水平(未检测到-0.469μgg-1)的非常短链CPs(vSCCPs,在部分室内灰尘中也发现了C9)。vSCCPs的优势同源组是C9和Cl6-7组,短链氯化石蜡的C13和Cl6-8组,MCCP的C14和Cl6-8组,LCCPs的C18和Cl8-9组。根据测量的浓度,vSCCPs,短链氯化石蜡,MCCP,和LCCP通过粉尘摄入和皮肤吸收对当地居民构成有限的人类健康风险。
Chlorinated paraffins (CPs), a group of mixtures with different carbon chain lengths and chlorine contents, are widely used as plasticizers and flame retardants in various indoor materials. CPs could be released from CP-containing materials into the ambient environment and then enter the human body via inhalation, dust ingestion and dermal absorption, resulting in potential effects on human health. In this study, we collected residential indoor dust in Wuhan, the largest city in central China, and focused on the co-occurrence and composition profiles of CPs as well as the resultant human risk via dust ingestion and dermal absorption. The results indicated that CPs with C9-40 were ubiquity in indoor dust with medium-chain CPs (MCCPs, C14-17) as the main components (6.70-495 μg g-1), followed by short-chain CPs (SCCPs, C10-13) (4.23-304 μg g-1) and long-chain (LCCPs, C≥18) CPs (3.68-331 μg g-1). Low levels (not detected-0.469 μg g-1) of very short-chain CPs (vSCCPs, C9) were also found in partial indoor dust. The dominant homolog groups were C9 and Cl6-7 groups for vSCCPs, C13 and Cl6-8 groups for SCCPs, C14 and Cl6-8 groups for MCCPs, and C18 and Cl8-9 groups for LCCPs. Based on the measured concentrations, vSCCPs, SCCPs, MCCPs, and LCCPs posed limited human health risks to local residents via dust ingestion and dermal absorption.