Median Neuropathy

中位神经病变
  • 文章类型: Journal Article
    方法:我们介绍了一例II型(骨内)正中神经卡压的患者,该患者是根据临床检查和磁共振成像诊断的,并接受了内侧上髁截骨术治疗,神经溶解,并在受伤后一个月内将神经移位到其解剖位置。我们的患者在5个月时完全恢复了运动和感觉,具有完整的功能和握力。
    结论:肘关节后外侧脱位后正中神经卡压是一种罕见的并发症,文献报道约40例。此病例说明了及时诊断和治疗的重要性。
    METHODS: We present a case of type II (intraosseous) entrapment of the median nerve in a patient who was diagnosed based on clinical examination and magnetic resonance imaging and who was treated with medial epicondyle osteotomy, neurolysis, and transposition of the nerve to its anatomical position within a month of injury. Our patient made a complete motor and sensory recovery at 5 months with complete functionality and grip strength.
    CONCLUSIONS: Median nerve entrapment after posterolateral elbow dislocation is a rare complication with roughly 40 cases reported in the literature. This case illustrates the importance of prompt diagnosis and treatment.
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  • 文章类型: Journal Article
    目的:使用一套护理过程质量措施对疑似腕管综合征(CTS)进行电诊断测试,研究小组先前记录了电诊断测试实践和对质量措施的遵守情况的巨大差异。本研究旨在通过在测试实践中整合可接受的变化来增强质量措施的适用性和有效性。
    方法:我们从5个专业学会招募了13位电诊断医学专家。专家反复提炼出五项质量措施,然后对精制质量措施(1-9量表)的有效性进行评级。在这个过程中,专家们审查了关于遵守现有质量措施和电诊断测试实践变化的数据,并考虑了美国神经肌肉和电诊断医学协会最近发表的质量测量。
    结果:三种质量措施(CTS手术前的电诊断测试,电诊断测试期间的温度评估,严重正中神经病的电诊断标准)几乎没有经过改进,并且被评为有效(中位数8-9)。两项措施(电诊断的基本组成部分,将电诊断测试解释为中位神经病的标准)在修订后被判定为有效(中位数8).对于这些措施,专家对感觉或混合神经传导研究的推荐成分的评级各不相同:专家对感觉峰值潜伏期的使用达成的共识大于发作潜伏期或感觉速度。
    结论:这项研究产生了质量措施,为可疑CTS的电诊断测试提供了最低标准,该标准比以前的版本更全面,更细致。未来的工作可以评估可行性,可靠性,以及这些细化措施在不同医师实践中的有效性。
    OBJECTIVE: Using a set of process-of-care quality measures for electrodiagnostic testing in suspected carpal tunnel syndrome (CTS), the research team previously documented large variations in electrodiagnostic testing practices and adherence to quality measures. This study sought to enhance the applicability and validity of the quality measures by integrating acceptable variations in testing practices.
    METHODS: We recruited 13 expert electrodiagnostic medicine specialists from five specialty societies. The experts iteratively refined five quality measures, and then rated the validity of the refined quality measures (1-9 scale). During this process, the experts reviewed data on adherence to existing quality measures and variations in electrodiagnostic testing practices, and considered recently published quality measures from the American Association of Neuromuscular and Electrodiagnostic Medicine.
    RESULTS: Three quality measures (electrodiagnostic testing before surgery for CTS, temperature assessment during electrodiagnostic testing, and electrodiagnostic criteria for severe median neuropathy) underwent few refinements and were rated valid (medians 8-9). Two measures (essential components of electrodiagnosis, criteria for interpreting electrodiagnostic tests as median neuropathy) were judged valid (medians 8) after revisions. For these measures, experts\' ratings on the recommended components of sensory or mixed nerve conduction studies varied: agreement among the experts about the use of sensory peak latency was greater than for onset latency or sensory velocity.
    CONCLUSIONS: This study produced quality measures that provide minimum standards for electrodiagnostic testing for suspected CTS that are more comprehensive and nuanced than prior versions. Future work can assess the feasibility, reliability, and validity of these refined measures in diverse physician practices.
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  • 文章类型: Journal Article
    肠系膜心绞痛死亡率高。肠系膜上动脉阻塞是最常见的原因。越来越多,它是血管内管理,而不是通过开放的血运重建。尽管微创手术并发症的风险较低,重要的是要注意轻微并发症的长期后遗症。关于风险和并发症的患者教育对于更好的临床结果至关重要。经肱动脉造影手术的风险很低。在所有微创血管内手术中,对干预人员的术后警惕和对患者的书面教育建议至关重要。特别是因为这些有并发症的患者大多需要紧急手术矫正。
    Mesenteric angina has a high mortality rate. Occlusion of the superior mesenteric artery is the most common cause. Increasingly, it is managed endovascularly instead of by open revascularization. Despite the lower risk of complications in minimally invasive procedures, it is important to be mindful of long-term sequelae of minor complications. Patient education regarding risks and complications is paramount for better clinical outcomes. The risks of transbrachial angiography procedures are low. Postprocedural vigilance for interventionists and written educational advice to patients are paramount in all minimally invasive endovascular procedures, especially because most of these patients with a complication require urgent operative correction.
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  • 文章类型: Case Reports
    方法:一名65岁的女性患者,表现为右手腕弥漫性疼痛和肿胀,右手感觉异常,大鱼间消瘦。她的磁共振成像扫描提示腕部屈肌腱鞘炎,正中神经受多个水稻体压迫。她接受了切除活检和正中神经减压术。通过聚合酶链反应(GeneXpert)检测结核分枝杆菌,组织病理学发现干酪样肉芽肿。患者术后开始接受抗结核化疗。
    结论:在印度等地方病国家,结核性屈肌腱鞘炎必须始终是腕关节肿胀的鉴别诊断。
    METHODS: A 65-year-old female patient presented with complaints of diffuse pain and swelling in her right wrist with paresthesia in her right hand with thenar wasting. Her magnetic resonance imaging scan was suggestive of flexor tenosynovitis of the wrist with compression of the median nerve with multiple rice bodies. She underwent excisional biopsy along with median nerve decompression. Mycobacterium tuberculosis was detected by polymerase chain reaction (GeneXpert), and histopathology identified caseous granulomas. The patient was started on antitubercular chemotherapy postoperatively.
    CONCLUSIONS: In endemic countries such as India, tuberculous flexor tenosynovitis must always be a differential diagnosis in cases of wrist swelling with rice bodies.
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  • 文章类型: Journal Article
    中位单神经病很常见,腕管综合征是临床实践中最常见的获得性单神经病。然而,如果不能正确识别正中神经的其他疾病和许多已知的解剖学变异,则可能导致误诊和意外的手术并发症。许多遗传性和获得性疾病会影响腕部近端的正中神经,单独或伴有其他受影响的周围神经。认识到其他可能伪装成中位单神经病变的疾病可以避免误诊和误导管理。本章探讨正中神经解剖变异,障碍,和病变,强调在正中神经病的定位中需要仔细检查和电诊断研究。
    Median mononeuropathy is common, with carpal tunnel syndrome the most frequently encountered acquired mononeuropathy in clinical practice. However, other disorders of the median nerve and many known anatomical variants can lead to misdiagnosis and unexpected surgical complications if their presence is not correctly identified. A number of inherited and acquired disorders can affect the median nerve proximal to the wrist, alone or accompanied by other affected peripheral nerves. Recognizing other disorders that can masquerade as median mononeuropathies can avoid misdiagnosis and misguided management. This chapter explores median nerve anatomical variants, disorders, and lesions, emphasizing the need for careful examination and electrodiagnostic study in the localization of median neuropathy.
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  • 文章类型: Journal Article
    手腕的中间神经病,通常称为腕管综合征(CTS),是最常见的压迫性神经病。它是由空间有限的腕管内腕部正中神经的慢性压迫引起的。导致压迫病因的危险因素包括女性,肥胖,与工作相关的因素,和潜在的医疗条件,比如甲状腺功能减退,怀孕,和淀粉样变性.诊断是基于临床,尽管这些可能被解剖变化所混淆。电诊断研究,在诊断CTS时具有特异性和敏感性,支持诊断;然而,一个亚组可能呈现正常结果。成像技术的出现,包括超声波和核磁共振,进一步协助诊断过程。CTS的管理分为非手术方法,包括手部治疗,夹板和皮质类固醇注射,腕管减压手术.尽管已经开发了几种手术技术,没有一种方法比另一种方法更有效。这些管理方法中的每一种在提供症状缓解方面都是有效的,并且在病症的不同严重程度下使用。有,然而,对标准化诊断标准缺乏共识,以及何时以及向谁转诊手术。
    Median neuropathy at the wrist, commonly referred to as carpal tunnel syndrome (CTS), is the most common entrapment neuropathy. It is caused by chronic compression of the median nerve at the wrist within the space-limited carpal tunnel. Risk factors that contribute to the etiology of compression include female gender, obesity, work-related factors, and underlying medical conditions, such as hypothyroidism, pregnancy, and amyloidosis. The diagnosis is made on clinical grounds, although these can be confounded by anatomical variations. Electrodiagnostic studies, which are specific and sensitive in diagnosing CTS, support the diagnosis; however, a subgroup may present with normal results. The advent of imaging techniques, including ultrasound and MRI, further assists the diagnostic process. The management of CTS is divided into the nonsurgical approaches that include hand therapy, splinting and corticosteroid injection, and surgical decompression of the carpal tunnel. Although several surgical techniques have been developed, no one method is more effective than the other. Each of these management approaches are effective at providing symptom relief and are utilized at different severities of the condition. There is, however, a lack of consensus on standardized diagnostic criteria, as well as when and to whom to refer patients for surgery.
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  • 文章类型: Journal Article
    肘部正中神经干的选择性分支受累导致骨间前神经(AIN)综合征是一种罕见的周围神经病变。由于成像技术的进步和报告的病例数量的增加,这种情况最近在医学界引起了越来越多的关注。在这篇文章中,我们探讨了正中神经干的地形解剖和与AIN麻痹相关的临床特征。我们的重点扩展到通过MRI和超声检查(US)研究捕获的独特表现,强调值得注意的发现,如神经束肿胀,不完全收缩,沙漏状收缩,和扭转,特别是在正中神经的后/后内侧区域。手术观察进一步增强了对这种复杂神经病的理解。高分辨率MRI不仅可以揭示AIN和正中神经区域的神经支配变化,而且还可以在不存在压缩结构的情况下阐明这些变化。强调了高分辨率MRI和US在诊断这种情况和指导制定最佳治疗策略中的关键作用。
    Selective fascicular involvement of the median nerve trunk above the elbow leading to anterior interosseous nerve (AIN) syndrome is a rare form of peripheral neuropathy. This condition has recently garnered increased attention within the medical community owing to advancements in imaging techniques and a growing number of reported cases. In this article, we explore the topographical anatomy of the median nerve trunk and the clinical features associated with AIN palsy. Our focus extends to unique manifestations captured through MRI and ultrasonography (US) studies, highlighting noteworthy findings, such as nerve fascicle swelling, incomplete constrictions, hourglass-like constrictions, and torsions, particularly in the posterior/posteromedial region of the median nerve. Surgical observations have further enhanced the understanding of this complex neuropathic condition. High-resolution MRI not only reveals denervation changes in the AIN and median nerve territories but also illuminates these alterations without the presence of compressing structures. The pivotal roles of high-resolution MRI and US in diagnosing this condition and guiding the formulation of an optimal treatment strategy are emphasized.
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  • 文章类型: English Abstract
    关于周围神经和肌肉的复杂解剖关系,肌腱,筋膜以及它们在这些解剖结构中的长期过程以及与骨结构的额外紧密接触,他们容易患局部压迫综合症。因此产生了绝大多数的截留综合征-在文献中对几乎每一根神经都有很好的描述。本文的目的是概述症状,标志,诊断研究和治疗选择,尤其是解决鲜为人知的综合症。上臂和肩部区域的压迫综合征包括肩胛骨上神经综合征,在空间四边形内压迫腋神经和在胸壁压迫长胸神经。上肢提供了各种罕见的压迫综合征,如前旋子大圆综合征和前骨间综合征,都是前臂正中神经受压所致。上肢远端桡神经过程中的压迫性神经病也称为旋后肌综合征。Guyon管综合征是尺侧,相当于众所周知的腕管综合征。在奇尔痛感觉异常的情况下,可以看到桡神经浅层感觉分支受压。在下肢,各种神经,特别是在腹股沟和大腿区域可以被压缩,因为他们通过狭窄的空间之间的腹部肌肉或下面的腹股沟韧带。股外侧皮神经受压是最常见的综合征。股神经和闭孔神经的压迫综合征通常是医源性的。膝盖周围疼痛,尤其是外侧部分和以下的矫形手术的膝盖,可能是由于隐神经的髌下小分支的压迫或病变引起的。另一个可能未被诊断的综合征是梨状肌综合征,坐骨神经在穿过某些肌肉结构时被卡住。在下肢远端,腓骨和胫神经可以在多个部位被压缩,临床上称为腓骨神经麻痹,由腓骨头周围的神经压迫引起,前和后骨隧道综合征,和莫顿的meta骨痛。
    AngesichtsihrerlangenVerläufe,denkomplexTopographienzwischenMuskeln,StrakturensindpirperiateNervenprädisponietfürkaleKompressionen.达拉乌斯的结果是精神接触综合征-快速接触神经。症状,诊断和治疗吉本,wobeiersichaufdiewenigerbekankantensyndrorinkonzentriert.ZudenseltenenKompressionssyndromenimBereichdesSchultergürtelsgehörendasSuprascapularis-Syndrom,腋下悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊悬吊。ImUnterarmsinddasM.pronator-teres-undN.osinterseus-forthor-SyndromalsseltenereKompressionssyndesN.medianusbeschrieben.AmUnterarmverlafdesN.radialiskanndasSupinatorlogensyndromauftreten.DasLogedeGuyon-SyndromliefertdasulnarseitgePendantzumweitausbekannterenKarpaltunelsyndromderHand.BeiderCheralgiaparaestheticahandeltessichumEinengungdessensiblenN.radialis-AsteszumDaumenrücken.AnderunterenExtremitätkönnnensämtlicheNervenderLeesten-undOberschenkelregioneingeengtwerden,Bauchmuskulaturbzw.这就是为什么我们要在莱斯坦班德这样做。偏瘫口蹄疫。NahezunuriatrogentretenEngpässedesN.femoralisoderN.obturatoriusauf.BeilateralenSchmerzeninderdistalenOberschenkel-/KnieregionvorallemnachorphoteschenEingriffenamKniegelenksollteanKompressionoderLäsiondesintrapatellarenN.Saphenus-Astesgedachtwerden.DasPiriformislücken-SyndrombeschreibteinewahrscheinlichmuskuläreEinengungdesN.ImUnterschenkel-undFubereichexistierenmehrreeKompressionsdesN.peronaeusunddesN.tibialis,Darunter死于Fibulaköpfchen的神经压迫,DasvordereandhintereTarstunnelsyndromunddieMorton-Metatarsalgie.
    In regard to the complex anatomical relationship of peripheral nerves and muscles, tendons, fasciae as well as their long course within those anatomical structures and additional close contact to bony structures, they are prone to suffer from local compression syndromes. Hence creating a vast majority of entrapment syndromes - well described in literature for almost every single nerve. The purpose of this article is to give an overview of symptoms, signs, diagnostic studies and treatment options, addressing especially the less known syndromes. Compression syndromes of the upper arm and shoulder region include the suprascapular nerve syndrome the compression of the axillary nerve within the spatium quadrilaterale and the compression of the long thoracic nerve at the chest wall. The upper extremity offers a variety of infrequent entrapment syndromes, as the pronator teres syndrome and anterior interosseus syndrome, both resulting from pressure to the median nerve in the forearm. Compression neuropathy in the course of the radial nerve in the distal upper extremity is also known as supinator syndrome. Guyon\'s canal syndrome is the ulnar side equivalent to the well-known carpal tunnel syndrome. In the case of a Cheiralgia paresthetica, a compression of a sensory branch of the superficial radial nerve can be seen. In the lower extremities, a variety of nerves especially in the groin and thigh area can be compressed as they pass through the narrow spaces between the abdominal muscles or underneath the inguinal ligament. Compression of the lateral femoral cutaneous nerve is the most common syndrome. Compression syndromes of the femoral and obturator nerves are most often iatrogenic. Pain around the knee, especially the lateral part and following orthopedic procedures of the knee, can arise from a compression or a lesion of a small infrapatellar branch of the saphenous nerve. Another probably underdiagnosed syndrome is piriformis syndrome, resulting from an entrapment of the sciatic nerve as it passes through certain muscular structures. In the distal lower extremity, the peroneal and tibial nerves can be compressed at multple sites, clinically known as peroneal nerve paralysis resulting from nerve compression around the fibular head, the anterior and posterior tarsal tunnel syndrome, and Morton\'s metatarsalgia.
    Angesichts ihrer langen Verläufe, den komplexen Topographien zwischen Muskeln, unter Bändern und Muskelfaszienkanten sowie dem Verlauf nahe knöcherner Strukturen sind periphere Nerven prädisponiert für lokale Kompressionen. Daraus resultieren viele Engpasssyndrome – für fast jeden Nerv ist ein solches beschrieben. Der Artikel soll eine systematische Übersicht über Symptome, Diagnostik und Therapie geben, wobei er sich auf die weniger bekannten Syndrome konzentriert.Zu den seltenen Kompressionssyndromen im Bereich des Schultergürtels gehören das Suprascapularis-Syndrom, das Kompressionssyndrom des N. axillaris im spatium quadrilaterale und die Kompression des N. thoracicus longus. Im Unterarm sind das M. pronator-teres- und N. interosseus-anterior-Syndrom als seltenere Kompressionssyndrome des N. medianus beschrieben. Am Unterarmverlauf des N. radialis kann das Supinatorlogensyndrom auftreten. Das Loge de Guyon-Syndrom liefert das ulnarseitige Pendant zum weitaus bekannteren Karpaltunnelsyndrom der Hand. Bei der Cheralgia paraesthetica handelt es sich um eine Einengung des sensiblen N. radialis-Astes zum Daumenrücken. An der unteren Extremität können sämtliche Nerven der Leisten- und Oberschenkelregion eingeengt werden, die Passage zwischen den Blättern der schrägen Bauchmuskulatur bzw. unter dem Leistenband ist hierfür prädisponierend. Die Meralgia paraesthetica mit einer Affektion des N. cutaneus femoris lateralis ist hier das bekannteste Syndrom. Nahezu nur iatrogen treten Engpässe des N. femoralis oder N. obturatorius auf. Bei lateralen Schmerzen in der distalen Oberschenkel-/Knieregion vor allem nach orthopädischen Eingriffen am Kniegelenk sollte an eine Kompression oder Läsion des intrapatellaren N. Saphenus-Astes gedacht werden. Das Piriformislücken-Syndrom beschreibt eine wahrscheinlich muskuläre Einengung des N. ischiadicus und gilt als unterdiagnostiziert. Im Unterschenkel- und Fußbereich existieren mehrere Kompressionssyndrome des N. peronaeus und des N. tibialis, darunter die Nervenkompression am Fibulaköpfchen, das vordere und hintere Tarsaltunnelsyndrom und die Morton-Metatarsalgie.
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  • 文章类型: Case Reports
    背景技术肩胛骨综合征是一种罕见的临床实体,包括舟骨和头状骨折以及近端头状碎片的90度或180度旋转。该综合征在文献中几乎没有描述,头状片段的近端迁移仅在1995年由Mudgal等人报道。同时压迫正中神经是非常不幸的事件,提出了一个独特的案例。案例报告我们介绍了一个25岁男性的肩cap骨骨折脱位的独特案例,头状骨碎片在正中神经深处的掌侧脱位。对病人进行了X线和CT扫描,伤后数小时由一名手部专科医生治疗,以防止正中神经病变和缺血坏死的片段。使用Herbert螺钉治疗舟骨骨折的切开复位和内固定,并额外进行了3根K线。术后立即,急性神经系统症状已消退,放射学上已获得良好的减轻。术后一年,患者恢复了良好的手和手腕功能,没有伸展或弯曲ROM缺陷。结论在一个专门的中心,使用赫伯特螺钉和K线进行复位和固定的即时干预在我们的肩capapitate综合征病例中显示出良好的1年结果。尽管存在高风险的损伤模式,但仍避免了正中神经病和头状缺血性坏死的即将发生的并发症。
    BACKGROUND Scaphocapitate syndrome is a rare clinical entity consisting of a combined scaphoid and capitate fracture along with a 90- or 180-degrees rotation of the proximal capitate fragment. The syndrome is scarcely described in the literature, with proximal migration of the capitate fragment being reported only by Mudgal et al in 1995. Concurrent compression of the median nerve is a highly unfortunate event, suggesting a unique case presented here. CASE REPORT We present a unique case of scaphocapitate fracture-dislocation in a 25-year-old man with volar dislocation of the capitate\'s fragment deep to the median nerve. X-rays and CT scan were performed and the patient was treated few hours after the injury by a hand specialist, in order to prevent median neuropathy and avascular necrosis of the fragment. Open reduction and internal fixation utilizing a Herbert screw for the scaphoid fracture and 3 additional K-wires was performed. Immediately post-operatively, the acute neurological symptoms had subsided and good reduction was acquired radiologically. One year post-operatively the patient had regained good hand and wrist functionality, with no extension or flexion ROM deficits. CONCLUSIONS Immediate intervention in a specialized center with reduction and fixation utilizing a Herbert screw and K-wires showed favorable 1-year results in our case of scaphocapitate syndrome. The impending complications of median neuropathy and capitate avascular necrosis were avoided despite the high-risk injury pattern.
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  • 文章类型: Journal Article
    广泛的疼痛可能与几种肌肉骨骼疾病的社会心理方面有关,但是关于腕管综合征(CTS)的文献很少。
    为了确定疼痛程度与心理因素之间的关系(灾难,运动恐惧症,焦虑症状,和抑郁症)患有CTS的人。
    进行了横断面研究。独立变量是:疼痛强度,残疾(QuickDASH),症状持续时间,焦虑和抑郁症状,灾难,和运动恐惧症。主要结果是:疼痛程度(占总面积和类别“正中神经支配区域内的疼痛”与“正中神经外疼痛”的百分比)。采用Spearman相关系数进行相关分析。进行线性回归模型和二元逻辑回归(均具有正向选择)以确定疼痛程度的主要预测因子。
    包括48名参与者。灾难化(r=0.455;p=0.024)和残疾(r=0.448;p=0.024)与总疼痛范围之间存在中度正相关。回归模型表明,灾难化解释了疼痛程度变化的22%(β=0.003;95%CI:0.002-0.005),而运动恐惧症是最能解释中位外区域疼痛分布的变量(R2Nagelkerke=0.182)。对于其余的关联,发现了零或弱相关性。
    突变和运动恐惧症是CTS患者疼痛程度的主要指标。建议临床医生使用特定的问卷来检查患有CTS和更广泛的疼痛扩展的人是否存在灾难性或运动恐惧症。
    UNASSIGNED: Widespread pain may be related to psychosocial aspects in several musculoskeletal conditions, but the literature on carpal tunnel syndrome (CTS) is scarce.
    UNASSIGNED: To determine the relationship between pain extent and psychological factors (catastrophizing, kinesiophobia, anxiety symptoms, and depression) in people with CTS.
    UNASSIGNED: A cross-sectional study was conducted. The independent variables were: pain intensity, disability (QuickDASH), duration of symptoms, anxiety and depressive symptoms, catastrophizing, and kinesiophobia. The main outcome was: pain extent (% of total area and categories \"pain within the median nerve-innervated territory\" versus \"extra-median nerve pain\"). Correlation analysis was performed using Spearman\'s correlation coefficient. A linear regression model and binary logistic regression (both with forward selection) were performed to determine the main predictors of pain extent.
    UNASSIGNED: Forty-eight participants were included. A moderate positive correlation was found between catastrophizing (r = 0.455; p = 0.024) and disability (r = 0.448; p = 0.024) with total pain extent area. Regression models indicated that catastrophizing explained 22% of the variance in the pain extent (β = 0.003; 95% CI: 0.002-0.005), while kinesiophobia was the variable that best explained the distribution of pain in the extra-median territory (R2 Nagelkerke = 0.182). Null or weak correlations were found for the rest of the associations.
    UNASSIGNED: Catastrophizing and kinesiophobia were the main indicators of pain extent in people with CTS. Clinicians are advised to use specific questionnaires to check for the presence of catastrophizing or kinesiophobia in people with CTS and wider pain extension.
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