Maskne

maskne
  • 文章类型: Observational Study
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  • 文章类型: Journal Article
    无论是在医疗领域,或在人们的日常生活和健康保护,口罩的重要性越来越受到重视。痤疮,戴口罩后最常见的并发症,也叫maskne,已成功引入通用语言作为皮肤科医生咨询的共同话题。本研究旨在研究口罩患者和健康对照者戴口罩前后微生物区系的变化。在2023年夏天,我们从15名maskne患者和10名健康对照者中收集了50个样本,这些样本在长时间佩戴外科口罩之前和之后。采用具有V3-V4可变区的16S核糖体DNA测序和鉴定技术,探讨戴口罩引起的微生物组变化,分析微生物多样性的变化,并建立互动网络。LDA效应大小分析用于鉴定哪些细菌从门到属的相对丰度显示出显着变化。戴上面具后,maskne患者的微生物组变化明显大于健康对照组,α多样性和β多样性均低于戴口罩前的maskne患者和戴口罩后的健康对照者。共现网络分析显示,与其他群体相比,长时间戴口罩后的maskne患者网络的连通性和复杂性最低,但是最高的聚类属性,而健康对照则相反。许多可能对皮肤有益的微生物在戴上口罩后显著减少。在戴口罩之前和之后,健康对照几乎没有差异。
    Whether in the field of medical care, or in people\'s daily life and health protection, the importance of masks has been paid more and more attention. Acne, the most common complication after wearing masks, which is also called maskne, has been successfully introduced into the common language as a common topic of dermatologist consultations. This study aims to study the changes of microflora in maskne patients and healthy controls before and after wearing masks. In the summer of 2023, we collected a total of 50 samples from 15 maskne patients and 10 healthy controls before and after wearing surgical masks for a long time. 16 S ribosomal DNA sequencing and identification technology with V3-V4 variable region were adopted to explore the microbiome changes caused by mask wearing, analyze the changes in microbial diversity, and make interaction network. LDA effect size analysis was used to identify which bacteria showed significant changes in their relative abundance from phylum to genus. After wearing a mask, the microbiome of the maskne patients changed significantly more than that of the healthy controls, with both α diversity and β diversity lower than those of maskne patients before wearing masks and those of healthy controls after wearing masks. Co-occurrence network analysis showed that compared with other groups, the network of maskne patients after wearing masks for a long time had the lowest connectivity and complexity, but the highest clustering property, while the opposite was true for healthy controls. Many microbes that are potentially beneficial to the skin decreased significantly after wearing a mask. There was almost no difference in healthy controls before and after wearing a mask.
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  • 文章类型: Journal Article
    “Maskne”一直是口罩在遏制正在进行的SARS-CoV-2病毒或COVID19大流行中普遍接受和有效作用的负面衍生产品之一。几个因素有助于其病因,包括热,湿度,湿度机械摩擦和微生物群体失调在面罩的闭塞区域下的复杂相互作用。临床上,形态与粉刺和炎性痤疮的寻常痤疮没有很大不同,但是在面具覆盖的面部大致圆形区域上的特征分布。由于在不久的将来可能会继续使用口罩,比如戴一个合适面料的舒适口罩,使用一次性口罩,在更安全的地方增加无口罩期,避免在闭塞的皮肤上不必要地使用个人护理产品,适当和温和的清洁受影响的区域,间歇性拖除过多的皮脂和汗水,局部和全身治疗可能有助于其解决.
    \"Maskne\" has been one of the negative spinoffs of the universally acceptable and effective role of face mask in containing the ongoing pandemic of SARS-CoV-2 virus or COVID 19. Several factors contribute to its aetiopathogenesis including heat, humidity, mechanical friction and microbiome dysbiosis in a complex interplay under the occlusive area of the mask. Clinically, the morphology is not very different from acne vulgaris with comedones and inflammatory acne, but in a characteristic distribution over a roughly circular area of face covered by mask. Since the use of face masks is likely to continue in the near future, measures like wearing a comfortably fitting mask of appropriate fabric, using disposable masks, increasing mask-free period when at safer places, avoiding unnecessary use of personal care products over the occluded skin, proper and gentle cleaning of the affected areas, intermittent mopping off of the excessive sebum and sweat and use of specific, topical and systemic therapy could help in its resolution.
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  • 文章类型: Journal Article
    未经批准:随着Covid-19大流行,面具的使用增加了“面具”案件的频率。由于使用口罩而引起的局部生理变化引起了环境中酵母存在的变化,如痤疮和脂溢性皮炎。
    UNASSIGNED:目的是比较maskne地区马拉色菌物种的差异。
    未经评估:共有408名受试者戴口罩,每天至少4小时,持续6周或更长时间,212名痤疮患者受损,72名脂溢性皮炎患者,124名健康志愿者被纳入这项研究。从鼻唇沟地区及其对照耳廓地区采集了马拉色菌培养物的拭子样品。社会科学统计软件包(SPSS)第22版用于统计分析。
    未经证实:马拉色菌最常见于脂溢性皮炎组的鼻唇沟区域。马拉色菌更常见于痤疮和脂溢性皮炎患者的鼻唇沟区域,与每个患者的耳后区域相比,而不是健康的受试者。从鼻唇沟区分离出的球形支原体的比率在所有组中都很高,M.restricta的分离率较低(P<0.05)。
    未经证实:由于马拉色菌更常见于痤疮和脂溢性皮炎患者的鼻唇沟区域,越来越多的马拉色菌将引发针对这些酵母的抗体反应的炎症。具有这种炎症的知识将促进抗性痤疮和脂溢性皮炎的治疗。
    UNASSIGNED: With the Covid-19 pandemic, the use of masks has increased the frequency of \'maskne\' cases. Local physiological changes due to the use of mask have caused changes in the presence of yeasts in the environment, such as acne and seborrheic dermatitis.
    UNASSIGNED: The aim is to compare the differences of Malassezia species in the maskne region.
    UNASSIGNED: A total of 408 subjects wearing masks at least 4 h a day for 6 weeks or longer, compromised of 212 acne patients, 72 seborrheic dermatitis sufferers, and 124 healthy volunteers were included in this study. Swab samples were taken for Malassezia cultures from nasolabial area and their control retro auricular region. The Statistical Package for Social Sciences (SPSS) version 22 was used for the statistical analysis.
    UNASSIGNED: Malassezia species was most frequently found in the nasolabial region of the seborrheic dermatitis group. Malassezia species were more commonly isolated from the nasolabial region of acne and seborrheic dermatitis patients, compared to the retroauricular region of each patient, than the healthy subjects. The rate of M. globosa isolated from the nasolabial region was high in all groups, the isolation rate of M. restricta was low (P < 0.05).
    UNASSIGNED: As Malassezia species are more commonly isolated from the nasolabial region of acne and seborrheic dermatitis patients, the increasing numbers of Malassezia species will trigger inflammation with an antibody reaction against these yeasts. Treatment of resistant acne and seborrheic dermatitis will be facilitated with the knowledge of this inflammation.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    未经证实:“maskne”一词起源于SARSCoV-2(COVID-19)大流行期间;它是痤疮的一种变体,与连续戴口罩有关。Maskne主要是观测的,最常见的原因是接触刺激性皮炎。
    UNASSIGNED:每波COVID-19中,到医院就诊一个月的OPD病例的平均口罩使用百分比,即,在2020年6月的第一波中,在2021年4月的第二波期间和2021年12月的第三波期间进行了计算。我们还纳入了30例诊断为刺激性接触性皮炎(又称maskne)的患者和30例诊断为寻常痤疮的患者。所有年龄>18岁,从2020年4月到2021年12月。
    UNASSIGNED:2020年6月(第一波)有66%的人戴口罩,在2021年4月的第二波中增加到74%,在第三波中,只有23%的人在2021年12月戴口罩。
    未经ASSIGNED:Maskne和寻常痤疮的恶化可能是由于长期佩戴脏口罩所致。使用保湿剂和定期“面膜破裂”是maskne管理的重要方面。
    UNASSIGNED: The term \"maskne\" originated during the SARS CoV-2 (COVID-19) pandemic; it is a variant of acne associated with continuous wearing of face mask. Maskne is mainly observational, and the most common cause of maskne is contact irritant dermatitis.
    UNASSIGNED: The average mask use percentage by OPD cases visiting the hospital for a month in each wave of the COVID -19, that is, in the month of June 2020 during the first wave, in the month of April 2021 during the second wave and in the month of December 2021 during the third wave was calculated. We also included 30 patients with a diagnosis of irritant contact dermatitis aka maskne and 30 patients with diagnosis of acne vulgaris, all >18 years of age from April 2020 to December 2021.
    UNASSIGNED: 66% of people wore masks coming to hospital in the month of June 2020 (first wave) which increased to 74% during the second wave in the month of April 2021 and during the third wave only 23% of people wore masks in the month of December 2021.
    UNASSIGNED: Maskne and worsening of acne vulgaris can be due to wearing of dirty face masks for longer duration. Use of moisturizers and regular \"mask breaks\" are important aspects in management of maskne.
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  • 文章类型: Journal Article
    新冠肺炎疫情导致许多医护人员长时间接触紧身口罩,通向Maskne.“Maskne”定义为面膜使用后的痤疮。在COVID-19大流行期间,关于maskne的研究有限。这项研究的目的是确定医护人员中maskne发展的风险因素。227名医学生完成了一项横断面调查,住院医师,约翰霍普金斯医学院的护理专业学生,68.7%的参与者报告maskne的发展。手术面罩和呼吸器是工作中佩戴的最普遍的面罩类型。最常见的预防方法是使用温和的清洁剂和保湿剂。采用卡方分析进行数据分析。这项研究的结果表明,性别(p=0.003)和使用口罩的持续时间(p=0.048)是口罩发育的重要风险因素。这些因素是不可改变的,但可以用于更有针对性的预防教育。
    The COVID-19 pandemic has led to many healthcare workers having prolonged contact with tight-fitting masks, leading to maskne. \"Maskne\" is defined as acne secondary to mask use. There are limited studies on maskne during the COVID-19 pandemic. The objective of this study is to identify risk factors for the development of maskne amongst healthcare workers. A cross-sectional survey was completed by 227 medical students, resident physicians, and nursing students at Johns Hopkins Medicine, with 68.7% of participants reporting development of maskne. Surgical masks and respirators were the most prevalent mask types worn at work. The most common prevention methods were the use of mild cleansers and moisturizers. Chi-squared analysis was used for data analysis. The results of this study indicate that gender (p = 0.003) and duration of mask use (p = 0.048) are significant risk factors for maskne development. These factors are non-modifiable, but may be used for more targeted education for prevention.
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  • 文章类型: Journal Article
    背景:在SARS-CoV-2大流行期间,个人防护装备(PPE)成为预防COVID-19的新社会规范,但对皮肤屏障有影响。本研究旨在分析影响PPE佩戴的因素,遵循卫生规则,对面部皮肤的影响,包括医护人员(HCW)和非医护人员(N-HCW)中皮肤病的发作或恶化。
    方法:2020年,对300N-HCW和60个HCW进行了一项原始调查,其中有60个关于使用PPE和大流行之前和期间皮肤病变的问题。完成了横断面统计分析,以评估环境因素与maskne发生之间的相互作用。
    结果:N-HCW组包括74%的女性和26%的男性,平均年龄为24.67±0.74。在HCW受访者中,91.7%是女性,8.3%是男性,平均年龄为30.07±0.36岁。所有参与者都使用PPE。N-HCW的志愿者主要选择了一次性(53.3%)和可重复使用的口罩(37.3%),而HCW更喜欢手术(66.7%)和FFP2/FFP3/N95口罩(30%),几乎从未使用过可重复使用的口罩(3.3%)。HCW主要与PPE一起使用5-8小时,N-HCW每天使用PPE1-4小时。在大流行之前有皮肤病学问题的受访者更加了解口罩,并更加注意PPE的卫生。重要的是,HCW比N-HCW经历更严重的面部皮肤损伤(p<0.0001)。两组之间在遵循佩戴PPE的基本卫生规则方面有统计学意义,HCW在那里练习更多。
    结论:Maskne是当前亟待解决的问题。如果HCW开发maskne,他们应该得到帮助,例如在PPE中花费的有限时间和佩戴它的结果的治疗,因为它是发展maskne的主要触发因素。此外,关于正确使用和选择PPE的教育应该得到改善。
    BACKGROUND: During the SARS-CoV-2 pandemic, personal protective equipment (PPE) became the new social norm for preventing COVID-19, but with an impact on the skin barrier. This study aimed to analyze the factors influencing PPE wearing, following hygiene rules, and effect on facial skin, including onset or exacerbation of dermatoses among healthcare workers (HCW) and non-healthcare workers (N-HCW).
    METHODS: In 2020, an original survey was carried out among 300 N-HCW and 60 HCW with 60 questions about using PPE and skin lesions experienced before and during the pandemic. Cross-sectional statistical analysis was completed to assess the interplay between environmental factors and maskne occurrence.
    RESULTS: The N-HCW group included 74% females and 26% males with an average age 24.67 ± 0.74. Among HCW respondents 91.7% were women and 8.3% were men, with an average age of 30.07 ± 0.36. All participants used PPE. Volunteers for N-HCW mainly chose a disposable (53.3%) and reusable masks (37.3%), while HCW preferred surgical (66.7%) and FFP2/FFP3/N95 masks (30%) and almost never used reusable masks (3.3%). HCW mainly spent 5-8 h with PPE, and N-HCW spent 1-4 h with PPE/day. Respondents with dermatological problems before the pandemic were more aware of the maskne and paid more attention to hygiene with PPE. Significantly, HCW experienced more severe facial skin lesions than N-HCW (p < 0.0001). There was statistical significance in following the basic hygienic rules of wearing PPE between both groups, where HCW practiced them more.
    CONCLUSIONS: Maskne is a current and urgent problem to be cured. HCW should receive help if they develop maskne, such as limited time spent in PPE and treatment of the results of wearing it, as it is the main trigger of developing maskne. In addition, education about the correct use and choice of PPE should be improved.
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  • 文章类型: Journal Article
    背景:在持续的COVID-19爆发期间,口罩的使用越来越多,成为我们日常生活的一部分。穿着时,长时间的接触和微环境变化深刻地导致痤疮发作,定义为“maskne”。\"
    目的:我们旨在评估蜗牛分泌滤液的疗效和安全性,金盏花,和甘草根提取物组合血清(SCGS)治疗面膜。
    方法:这是一个随机的,双盲,安慰剂对照试验研究。这项研究招募了66名轻度至中度掩模的参与者。SCGS和安慰剂被随机分配给参与者,每天两次使用,持续12周。痤疮病变计数的百分比变化,研究人员全球评估痤疮(IGEA),皮脂水平,角膜测量水平,经皮水分流失(TEWL),Visia®红斑评分,和不良事件在基线至第12周每周4次评估。在第12周,所有参与者使用10点视觉模拟量表(VAS)评估他们的满意度得分。
    结果:在遮罩覆盖区域,在所有时间点,治疗组炎性痤疮病灶的减少百分比均显著大于安慰剂组(炎性病灶百分比变化系数=-33.89[95%CI-65.24,-2.53];p=0.03).此外,对同时使用痤疮治疗的参与者进行的亚组分析显示出类似的结果(12名参与者,系数=-50.30[95%-88.65,-11.95];p=0.01)。然而,非炎性病变无显著差异,所有的皮肤生物物理学,和群体之间的VAS。两组的不良事件均较轻,仅发生在少数病例中。
    结论:SCGS可显著改善炎性痤疮病变,并具有良好的耐受性,提示其在maskne中作为辅助治疗的作用。
    BACKGROUND: During the ongoing COVID-19 outbreak, face mask use has increased and became a part of our daily lives. While wearing, prolonged contact time and microenvironmental change profoundly lead to an acne flare-up, defined as \"maskne.\"
    OBJECTIVE: We aimed to assess the efficacy and safety of snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glaba root extract combination serum (SCGS) in treating the maskne.
    METHODS: This was a randomized, double-blind, placebo-controlled trial study. This study enrolled 66 participants with mild-to-moderate maskne. The SCGS and placebo were randomly assigned for participants to use twice daily for 12 weeks. Percentage change of acne lesion count, acne severity by Investigator Global Evaluation Acne (IGEA), sebum levels, corneometry levels, transepidermal water loss (TEWL), erythema score by Visia®, and adverse events were evaluated 4-weekly at baseline to Week 12. At Week 12, all participants evaluated their satisfaction scores using a 10-point visual analog scale (VAS).
    RESULTS: In the mask-covered area, the percent reduction in inflammatory acne lesions from the treatment group was significantly greater than the placebo group at all time points (coefficient of percentage change of inflammatory lesions = -33.89 [95% CI -65.24, -2.53]; p = 0.03). Also, a subgroup analysis with participants using concurrent acne treatments revealed similar results (12 participants, coefficient = -50.30 [95% -88.65, -11.95]; p = 0.01). However, there were no significant differences in non-inflammatory lesions, all skin biophysics, and VAS between groups. Adverse events were mild and occurred in a few cases in both groups.
    CONCLUSIONS: The SCGS could significantly improve inflammatory acne lesions and had a favorable tolerability profile, suggesting its role as an adjunctive treatment in maskne.
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