目的:回顾已发表的膀胱平滑肌肉瘤病例,并报告2例。
方法:使用关键字\'膀胱\'搜索数据库Pubmed和Hinari,“平滑肌肉瘤”和“平滑肌肿瘤”。对确定的14篇文章进行了审查,我们又提出了两个案例。
结果:报告的100多例病例中,77人被审查。关于标准治疗缺乏共识,对肿瘤的自然史和预后知之甚少,由于其发病率非常低。这些肿瘤发生在任何性别的老年人中,并以攻击行为为特征。通常会有不利的结果,肺部是最常见的转移部位。我们报告的另外两个病例具有不同的呈现和结果。
结论:由于这种罕见肿瘤的治疗经验有限,没有足够的数据表明最佳管理策略和预后.
OBJECTIVE: To review the published cases of leiomyosarcoma of the urinary bladder and to report two further cases.
METHODS: The databases Pubmed and Hinari were searched using the keywords \'bladder\', \'leiomyosarcoma\' and \'smooth muscle neoplasm\'. The 14 articles identified were reviewed, and we present a further two cases.
RESULTS: Of more than 100 cases reported, 77 were reviewed. There is a lack of consensus about the standard treatment, and little is known about the natural history and prognosis of the tumour, due to its very low incidence. These tumours occur in older adults of either sex and are characterised by an aggressive behaviour. There is usually an unfavourable outcome, with the lungs being the most common site of metastasis. The two further cases we report had a different presentation and outcome.
CONCLUSIONS: Because of the limited experience with this rare tumour, there are insufficient data to suggest the optimum management strategy and prognosis.