背景:对于全世界的癌症患者群体,诊断和治疗的同步扩大在生存率和生活质量方面有意义的提高.在先进的癌症疗法中,放射治疗(RT)和治疗是实现实用化的关键,高品质,和个性化精准医疗-针对个体患者和广泛人群的疾病表现,相像。旨在在世界不同地区相互学习,这里介绍的六个国家小插曲描绘了RT和theranosics基础设施的重新建立或改进方面的挑战和胜利。
方法:国际原子能机构(IAEA)召集了来自世界不同地区和背景的全球RT和theranosics专家,以确定相关挑战并报告其六个国家的进展:比利时,巴西,哥斯达黎加,乔丹,蒙古,和南非。这些账目都是整理好的,比较,并在此对比。
结果:共同的挑战依然存在,可以更有策略地评估和解决。可量化的差异需要人员。估计的放射肿瘤学家(RO),核医学医师(NMP),和医学物理学家(RT和核医学的MPs)在六个集体国家中的每百万居民分别在2.69-38.00ROs之间,1.00-26.00NMP,和0.30-3.45MP(表1),反映了国与国之间的不平等,这在很大程度上与世界银行国家收入分层相匹配。
结论:在全球范围内建立的RT和核医学发展目标已被证明是难以捉摸的。可以通过加强方法来加快进展速度,例如更可持续的分阶段实施;更好的多国网络以分享经验教训;例行的质量和安全审计;以及采用创新的能力建设,节约资源,尖端技术方法。卫生部等机构,专业社团,原子能机构将在召集和协调更具创新性的RT和theranosics转化研究方面发挥关键作用,包括扩展细致入微的全球数据库指标,reach,最有意义地加强里程碑。
■与世卫组织25×25非传染性疾病目标一致;WHA70.12和WHA76.5决议。
BACKGROUND: For cancer patient populations worldwide, the synchronous scale-up of diagnostics and treatments yields meaningful gains in survival and quality of life. Among advanced cancer therapies, radiotherapy (RT) and theranostics are key to achieving practical, high-quality, and personalized precision medicine - targeting disease manifestations of individual patients and broad populations, alike. Aiming to learn from one another across different world regions, the six country vignettes presented here depict both challenges and victories in de novo establishment or improvement of RT and theranostics infrastructure.
METHODS: The International Atomic Energy Agency (IAEA) convened global RT and theranostics experts from diverse world regions and contexts to identify relevant challenges and report progress in their own six countries: Belgium, Brazil, Costa Rica, Jordan, Mongolia, and South Africa. These accounts are collated, compared, and contrasted herein.
RESULTS: Common challenges persist which could be more strategically assessed and addressed. A quantifiable discrepancy entails personnel. The estimated radiation oncologists (ROs), nuclear medicine physicians (NMPs), and medical physicists (MPs for RT and nuclear medicine) per million inhabitants in the six collective countries respectively range between 2.69-38.00 ROs, 1.00-26.00 NMPs, and 0.30-3.45 MPs (Table 1), reflecting country-to-country inequities which largely match World Bank country-income stratifications.
CONCLUSIONS: Established goals for RT and nuclear medicine advancement worldwide have proven elusive. The pace of progress could be hastened by enhanced approaches such as more sustainably phased implementation; better multinational networking to share lessons learned; routine quality and safety audits; as well as capacity building employing innovative, resource-sparing, cutting-edge technologic approaches. Bodies such as ministries of health, professional societies, and the IAEA shall serve critical roles in convening and coordinating more innovative RT and theranostics translational research, including expanding nuanced global database metrics to inform, reach, and potentiate milestones most meaningfully.
UNASSIGNED: Aligned with WHO 25×25 NCDs target; WHA70.12 and WHA76.5 resolutions.