成年期的心脏代谢健康与儿童时期的社会经济地位(SEP)相关。尽管以前的研究已经对此进行了研究,但仍需要解决一些问题。例如,关于与时间关联的知识,暴露程度以及生活方式和成人SEP,对于解决心脏代谢疾病中日益增长的社会梯度至关重要。
这项研究包括一个子样本(N=264,50%的女性,年龄28-30)来自正在进行的队列研究。我们使用了国家登记册的组合,纵向问卷数据和临床数据。我们检查了儿童SEP与心脏代谢风险之间的关系,通过年轻成年期的多个风险标志物的评分来衡量。SEP指标包括母亲的教育水平和家庭收入。通过四种不同的生命历程模型评估了这种关联;潜在效应模型,路径模型,累积模型和社会流动模型。
我们发现母亲的教育水平与心脏代谢风险呈负相关。通过途径和累积生命历程模型评估该关联具有统计学意义,然而,通过潜在效应模型评估,统计上是微不足道的。没有观察到与社会流动性的特定关联。然而,成人教育水平高似乎对协会有保护性影响。在任何应用的生命过程模型中,家庭收入与心脏代谢风险之间均未发现关联。
儿童SEP低,以母亲的教育水平而不是家庭收入为代表,与成年后心脏代谢风险增加有关。曝光的积累,生活方式和成人教育程度对协会很重要。相比之下,代际社会流动似乎对这种关联没有特定的影响,我们也没有发现儿童期特定时间的证据.
Cardiometabolic health in adulthood is associated with socioeconomic position (SEP) in childhood. Although this has been studied by previous research several questions need to be addressed. E.g. knowledge about the association with timing, extent of the exposure as well as lifestyle and adult SEP, is essential to address the increasing social gradient in cardiometabolic diseases.
This study included a sub-sample (N = 264, 50% women, age 28-30) from an ongoing cohort study. We used a combination of national registers, longitudinal questionnaire data and clinical data. We examined the association between childhood SEP and cardiometabolic risk, measured by a score of multiple risk markers in young adulthood. SEP-indicators included mother\'s educational level and household income. The association was evaluated by four different life course models; the latent effects model, the pathway model, the cumulative model and the social mobility model.
We found an inverse association between mother\'s educational level and cardiometabolic risk. The association was statistically significant evaluated by the pathway and cumulative life course models, however statistically insignificant evaluated by the latent effects model. No specific association with social mobility was observed. However, high adult educational level seems to have a protecting impact on the association. No association was found between household income and cardiometabolic risk in any of the applied life course models.
Low childhood SEP, represented by mother\'s educational level but not household income, is associated with increased cardiometabolic risk in young adulthood. The accumulation of exposure, lifestyle and adult educational attainment are important for the association. In contrast, intergenerational social mobility does not seem to have a specific impact on the association and we find no evidence for a particular timing in childhood.