目的:本研究旨在描述人口统计概况,患病率,模式,以及向利比里亚眼科中心就诊的40岁以上患者的视网膜静脉阻塞(RVO)的危险因素,约翰·F·肯尼迪纪念医疗中心,蒙罗维亚,利比里亚。
方法:对2017年7月至2021年2月到利比里亚眼科中心就诊的患者进行了回顾性研究。在此期间,共检查了17506名新患者,其中10813名患者年龄超过40岁。数据收集自电子病历系统数据库。收集的数据中的变量包括年龄,性别,location,受影响的眼睛偏侧,未矫正视力,最佳矫正视力,眼内压,眼部诊断,系统性风险因素,和相关的并发症。
结果:在10813名患者中,在111例患者中发现RVO,总患病率为1.03%(95%置信区间0.80-1.2)。在确定的人群中,中央RVO(CRVO)比分支RVO(BRVO)更常见,男女比例相似。任何RVO的平均年龄为64.45±12.27标准差(SD)岁(P=0.734)。大多数RVO病例来自Lofa(n=20;18%)。55例(61.1%)患者有高血压,5(5.6%)患有糖尿病,6例(6.7%)有血脂异常。24例(26.7%)患者存在一个以上的系统性危险因素。然而,所有系统性危险因素均无统计学意义.CRVO患者视力受影响最大,45例(63.4%)患者的视力<3/60,而BRVO患者为12例(30.0%)。34例(30.6%)患者存在青光眼。最常见的眼部并发症是黄斑水肿(n=62,55.8%),其次是玻璃体出血(n=8,7.2%)。
结论:在利比里亚40岁以上的研究人群中检测到1.03%的RVO,CRVO比BRVO更常见。RVO在利比里亚人群中的临床表现首次提供了对疾病负担的见解和进一步研究的机会。
OBJECTIVE: This study aims to describe the demographic profile, prevalence, pattern, and risk factors for retinal vein occlusion (RVO) in patients over 40 years of age presenting to the
Liberia Eye Centre, John F Kennedy Memorial Medical Centre, Monrovia,
Liberia.
METHODS: A retrospective study was conducted on patients presenting to
Liberia Eye Centre from July 2017 to February 2021. A total of 17506 new patients were examined during this period out of which 10813 patients were over 40 years of age. Data were collected from the electronic medical record system database. The variables in the collected data included age, gender, location, laterality of eye affected, uncorrected visual acuity, best-corrected visual acuity, intraocular pressure, ocular diagnosis, systemic risk factors, and associated complications.
RESULTS: Of the 10813 patients, RVO was found in 111 patients with an overall prevalence rate of 1.03% (95% confidence interval 0.80-1.2). Central RVO (CRVO) was more common than branch RVO (BRVO) in the defined population with similar proportions of both genders. The mean age for any RVO was 64.45 ± 12.27 standard deviation (SD) years (P = 0.734). Majority of the cases of RVO were from Lofa (n = 20; 18%). Fifty-five (61.1%) patients had hypertension, 5 (5.6%) had diabetes mellitus, and 6 (6.7%) had dyslipidemia. More than one systemic risk factor was present in 24 (26.7%) patients. However, none of the systemic risk factors were statistically significant. Visual acuity was most affected in patients with CRVO, with a visual acuity of <3/60 in 45 (63.4%) patients compared to 12 (30.0%) in BRVO patients. Glaucoma was present in 34 (30.6%) patients. The most common ocular complication was macular edema (n = 62, 55.8%) followed by vitreous hemorrhage (n = 8, 7.2%).
CONCLUSIONS: RVO was detected in 1.03% of the study population over the age of 40 years in
Liberia, CRVO being more common than BRVO. The clinical presentation of RVO in the Liberian population for the first time provides insight into the burden of the disease and opportunity for further research.