未经证实:多囊卵巢综合征(PCOS)患者表现出胰岛素抵抗和肥胖增加等共同特征,已知与交感神经过度活跃有关。
UNASSIGNED:本研究的目的是分析PCOS女性的心率变异性特征。比较PCOS女性和明显健康女性的心率变异性(HRV)频域参数。研究BMI和血压等心脏代谢参数对频域HRV参数的影响。
UNASSIGNED:共有30名年龄在20至40岁(根据鹿特丹标准)的PCOS妇女作为病例,30名年龄匹配的排卵周期正常的妇女作为对照。使用心电图机(ECG)记录HRV。评估了以下频域参数:总功率,甚低频(VLF),VLF%,低频(LF),LF%,LFnu,高频(HF),HF%,HFnu,LF/HF比,短期变异性(SD1),和长期变异性(SD2),分别。
未经证实:病例平均年龄为28.03±5.33岁。PCOS女性的平均BMI为25.39±2.69kg/m2。共有18个(60%)的BMI>25kg/m2。病例的BMI明显增高,腰臀比,和血压与对照组相比。没有一个对照的BMI>25kg/m2。大多数病例(66.7%)的收缩压/舒张压(SBP/DBP)>130/85mmHg,而对照组只有6(20%)(P<0.001)。对于不同的频域参数,两组间VLF和LF无统计学差异。平均VLF%,LF%,LF(nu),与对照组相比,病例中的LF/HF明显更高。对于所有人,与对照组相比,病例的其他平均值显着降低(P<0.05)。
未经授权:自主神经系统受女性PCOS状态的影响,可以看到交感神经过度活跃。
UNASSIGNED: Polycystic ovary syndrome (PCOS) patients shows common features like increased insulin resistance and adiposity, which have been known to correlate with sympathetic hyperactivity.
UNASSIGNED: The aim of this study is to analyze the characteristics of heart rate variability in women with PCOS. To compare frequency domain parameters of heart rate variability (HRV) between women with PCOS and apparently healthy women. To study the impact of cardiometabolic parameters such as BMI and blood pressure on frequency-domain HRV parameters.
UNASSIGNED: A total of 30 women with PCOS aged 20 to 40 years (as per Rotterdam criteria) were enrolled as cases and 30 age-matched women having normal ovulatory cycles were enrolled as controls. HRV was recorded using an electrocardiography machine (ECG) machine. The following frequency-domain parameters were assessed: Total power, Very low frequency (VLF), VLF%, Low Frequency (
LF),
LF%,
LF nu, High frequency (HF), HF%, HF nu,
LF/HF ratio, short-term variability (SD1), and long-term variability (SD2), respectively.
UNASSIGNED: Mean age of cases was 28.03 ± 5.33 years. Mean BMI of PCOS women was 25.39 ± 2.69 kg/m2. A total of 18 (60%) had BMI >25 kg/m2. Cases had significantly higher BMI, waist hip ratio, and blood pressure as compared with controls. None of the controls had BMI >25 kg/m2. Majority of cases (66.7%) had systolic blood pressure/diastolic blood pressure (SBP/DBP) >130/85 mmHg as compared with only 6 (20%) of controls (P < 0.001). For different frequency domain parameters, no statistically significant difference between two groups was observed for VLF and
LF. Mean VLF%,
LF%,
LF (nu), and
LF/HF were significantly higher in cases as compared with controls. For all, the other mean value was significantly lower in cases as compared with that of controls (P < 0.05).
UNASSIGNED: Autonomic nervous system is affected by PCOS status of women, and sympathetic hyperactivity is seen.