目的:分析中国老年慢性心力衰竭患者认知功能衰弱的相关因素。
方法:横截面设计。
方法:从遵义医学院附属医院心内科随机抽取2021年8月至2022年11月间慢性心力衰竭患者421例(年龄≥60岁)。FRAIL量表,迷你精神状态检查,15项老年抑郁量表,社会支持评定量表,使用简短的迷你营养评估和匹兹堡睡眠质量指数进行测量和评估。收集患者的人口统计学和临床特征。要选择初始变量,应用最小绝对收缩选择算子,然后采用logistic回归分析确定相关因素。
结果:在421名患有慢性心力衰竭的老年人中,83例(19.7%)表现为认知虚弱。在31个变量中,通过最小绝对收缩选择算子回归选择了7个。最后,多变量逻辑回归显示,年龄,月薪,饮酒,NYHA分类,住院时间,抑郁和营养不良风险/营养不良与认知虚弱独立相关.
结论:在患有慢性心力衰竭的老年人中,认知虚弱的比例很高,应该引起关注。此外,在认知脆弱的背景下,在老年慢性心力衰竭患者中,有必要对其进行诊断,并制定干预措施以预防或逆转认知功能衰弱.
结论:我们的研究结果强调了评估老年慢性心力衰竭患者认知功能衰弱的必要性,并为医务人员制定预防或逆转认知功能衰弱的个性化干预措施提供了新的视角和科学依据。
■本研究报告符合STROBE横断面研究报告指南。
■没有患者或公共捐款。
OBJECTIVE: To analyse factors associated with cognitive frailty among older chronic heart failure patients in China.
METHODS: A cross-sectional design.
METHODS: Between August 2021 and November 2022, a total of 421 chronic heart failure patients (age ≥60 years) were randomly selected from the cardiology department of the affiliated hospital of Zunyi Medical University. The FRAIL scale, Mini-Mental State Examination, 15-item Geriatric Depression Scale, Social Support Rating Scale, Short-form Mini Nutritional Assessment and Pittsburgh Sleep Quality Index were utilized for measurement and evaluation. The demographic and clinical characteristics of patients were collected. To select initial variables, the Least Absolute Shrinkage Selection Operator was applied, and then logistic regression analysis was used to confirm associating factors.
RESULTS: Among 421 elderly people with chronic heart failure, 83 cases (19.7%) showed cognitive frailty. Of 31 variables, seven were selected by Least Absolute Shrinkage Selection Operator regression. Finally, multivariate logistic regression revealed that the age, monthly salary, drinking, NYHA classification, length of hospital stay, depression and malnutrition risk/malnutrition were independently associated with cognitive frailty.
CONCLUSIONS: The high proportion of cognitive frailty in older people with chronic heart failure should be concerned. Additionally, in the setting of cognitive frailty, efforts to diagnose it and develop interventions to prevent or reverse cognitive frailty status among older chronic heart failure patients are necessary.
CONCLUSIONS: The findings of our study highlight the necessity to evaluate cognitive frailty in older people with chronic heart failure and provide a new perspective and scientific basis for medical staff to develop individualized and specific interventions to prevent or reverse cognitive frailty status.
UNASSIGNED: This study has been reported in compliance with STROBE reporting guidelines for cross-sectional studies.
UNASSIGNED: No Patient or Public Contribution.