■这项研究评估了用同心针进行抖动分析以评估重症肌无力(MG)的疾病严重程度的实用性,将抖动的变化与临床状态相关联,并确定任何不一致的原因。
■我们对82例MG患者进行了回顾性图表回顾,并提取了人口统计学数据,MG亚型,抗体状态,临床量表,电生理学,以及基线和随访时的干预措施。
■基线MGII分数与抖动(r=0.25,p=0.024)和异常对(r=0.24,p=0.03)相关。28个月后,MGII分数与抖动相关(r=0.31,p=0.006),异常对(r=0.29,p=0.009),并与块配对(r=0.35,p=0.001)。MGII分数的变化与抖动的变化相关(r=0.35,p=0.002),异常对(r=0.27,p=0.014),并与块配对(r=0.36,p=0.001)。
■同心针抖动分析可能具有评估MG中基线和序贯疾病严重程度的潜力。
■这项研究强调了通过使用同心针抖动分析进行精确评估和管理来改善MG患者护理的潜力,以提高MG诊断和监测疾病活动的准确性。
UNASSIGNED: This study assesses the utility of
jitter analysis with concentric needles to evaluate disease severity in myasthenia gravis (MG), correlate changes in
jitter with clinical status as well as identify reasons for any discordance.
UNASSIGNED: We performed a retrospective chart review of 82 MG patients and extracted data on demographics, MG subtype, antibody status, clinical scales, electrophysiology, and interventions at baseline and follow-up.
UNASSIGNED: Baseline MGII scores correlated with
jitter (r = 0.25, p = 0.024) and abnormal pairs (r = 0.24, p = 0.03). After 28 months, MGII scores correlated with
jitter (r = 0.31, p = 0.006), abnormal pairs (r = 0.29, p = 0.009), and pairs with blocks (r = 0.35, p = 0.001). Changes in MGII scores correlated with changes in jitter (r = 0.35, p = 0.002), abnormal pairs (r = 0.27, p = 0.014), and pairs with blocks (r = 0.36, p = 0.001).
UNASSIGNED: Concentric needle
jitter analysis may have the potential to evaluate baseline and sequential disease severity in MG.
UNASSIGNED: This study highlights the potential for improved MG patient care through precise assessment and management using concentric needle jitter analysis to improve the accuracy of MG diagnosis and monitoring of disease activity.