目的:本研究的目的是评估基于公式的体积测量和使用不同软件包的3D体积分析在计算术前颌骨囊性病变体积时的准确性。次要目的是评估3种成像软件程序在CBCT图像中测量下颌囊性病变体积的可靠性和准确性。
方法:本研究由两部分组成:使用2个干燥的人类下颌骨的体外部分,用于创建模拟的溶骨性病变,以评估体积分析和基于公式的体积的准确性。作为黄金标准,通过使用快速软硅胶(Vinylight)进行印模,然后量化复制品的体积来确定每个骨缺损的体积。之后,使用高分辨率CBCT扫描每个牙槽.回顾性部分使用从口腔颌面放射科门诊诊所数据库中获取的CBCTX射线照片,牙科学院,Minia大学评估了3个软件包的可靠性。使用3个软件包(MIMICS-OnDemand和InVesalius软件)导出体积数据集用于体积定量。此外,计算病变的三个最大正交直径,并使用椭圆体公式评估体积。当弗里德曼检验显著时,邓恩检验用于成对比较。使用Cronbach的α可靠性系数和类内相关系数评估了考试者之间的一致性。
结果:关于回顾性部分的结果,通过方程式和不同软件进行的体积测量之间存在统计学上的显着差异(P值<0.001,效应大小=0.513)。使用不同软件包测量囊性病变的观察者间可靠性非常好。与InVesalius发现了最高的体量测量者之间的一致性(Cronbach'salpha=0.992)。另一方面,干下颌骨体积测量和黄金标准之间有统计学上的显着差异。所有软件均显示出统计学上显着低于黄金标准的干下颌骨体积测量值。
结论:使用InVesalius计算机辅助评估囊性病变体积,OnDemand,和MIMICS是一个现成的,易于使用,非侵入性选择。与基于公式的体积相比,它具有优势,因为它给出了病变的确切形态,因此可以在手术前检测到潜在的问题。与真实体积相比,使用InVesalius软件进行的体积分析在确定人类尸体下颌骨中模拟的根尖缺陷的体积方面是准确的。InVesalius软件证明,开源软件可以强大而用户友好,具有使用成本最低的优势。
OBJECTIVE: The aim of this study was to assess the accuracy of formula-based volume measurements and the 3D volume analysis with different software packages in the calculation of preoperative cystic jaw lesions\' volume. The secondary aim was to assess the reliability and the accuracy of 3 imaging software programs for measuring the cystic jaw lesions\' volume in CBCT images.
METHODS: This study consisted of two parts: an in vitro part using 2 dry human mandibles that were used to create simulated osteolytic lesions to assess the accuracy of the volumetric analysis and formula-based volume. As a gold standard, the volume of each bone defect was determined by taking an impression using rapid soft silicone (Vinylight) and then quantifying the volume of the replica. Afterward, each tooth socket was scanned using a high-resolution CBCT. A retrospective part using archived CBCT radiographs that were taken from the database of the outpatient clinic of the oral and maxillofacial radiology department, Faculty of Dentistry, Minia University to assess the reliability of the 3 software packages. The volumetric data set was exported for volume quantification using the 3 software packages (MIMICS-OnDemand and InVesalius software). Also, the three greatest orthogonal diameters of the lesions were calculated, and the volume was assessed using the ellipsoid formula. Dunn\'s test was used for pair-wise comparisons when Friedman\'s test was significant. The inter-examiner agreement was assessed using Cronbach\'s alpha reliability coefficient and intra-class correlation coefficient.
RESULTS: Regarding the results of the retrospective part, there was a statistically significant difference between volumetric measurements by equation and different software (P value < 0.001, Effect size = 0.513). The inter-observer reliability of the measurements of the cystic lesions using the different software packages was very good. The highest inter-examiner agreement for volume measurement was found with InVesalius (Cronbach\'s alpha = 0.992). On the other hand, there was a statistically significant difference between dry mandible volumetric measurements and Gold Standard. All software showed statistically significantly lower dry mandible volumetric measurements than the gold standard.
CONCLUSIONS: Computer-aided assessment of cystic lesion volume using InVesalius, OnDemand, and MIMICS is a readily available, easy to use, non-invasive option. It confers an advantage over formula-based volume as it gives the exact morphology of the lesion so that potential problems can be detected before surgery. Volume analysis with InVesalius software was accurate in determining the volume of simulated periapical defects in a human cadaver mandible as compared to true volume. InVesalius software proved that open-source software can be robust yet user-friendly with the advantage of minimal cost to use.