目的:高血压是心血管疾病的主要危险因素,适当的血压控制往往难以捉摸。这项工作的目的是对高血压患者的等距抗阻训练(IRT)研究的试验数据进行荟萃分析,以确定IRT是否产生抗高血压作用。数据库搜索(PubMed,CINAHL,Cochrane中央控制试验登记册,和MEDLINE)确定了成人高血压患者IRT与久坐或假对照组的随机对照和交叉试验。
结果:我们在荟萃分析中纳入了12项研究(14个干预组),共有415名参与者。IRT降低收缩压(SBP),平均差(MD)-7.47mmHg(95CI-10.10,-4.84),P<0.01;舒张压(DBP)MD-3.17mmHg(95CI-5.29,-1.04),P<0.01;平均动脉血压(MAP)MD-7.19mmHg(95CI-9.06,-5.32),P<0.0001。办公室脉压和静息心率没有显著降低,24小时或日间动态血压(SBP,DBP)。夜间血压,然而,SBPMD-4.28mmHg(95CI-7.88,-0.67)显着降低,P=0.02,DBPMD-2.22mmHg(95CI-3.55,-0.88),P<0.01。IRT确实降低了SBP,DBP和MAP办公室和夜间门诊SBP和DBP,但不是高血压患者的24小时平均动态血压。
Hypertension is the primary risk factor for cardiovascular disease and adequate blood pressure control is often elusive. The objective of this work was to conduct a meta-analysis of trial data of isometric resistance training (IRT) studies in people with hypertension, to establish if IRT produced an anti-hypertensive effect. A database search (PubMed, CINAHL, Cochrane Central Register of Controlled Trials, and MEDLINE) identified randomised controlled and crossover trials of IRT versus a sedentary or sham control group in adults with hypertension.
We included 12 studies (14 intervention groups) in the meta-analyses, with an aggregate of 415 participants. IRT reduced systolic blood pressure (SBP), mean difference (MD) - 7.47 mmHg (95%CI - 10.10, - 4.84), P < 0.01; diastolic blood pressure (DBP) MD - 3.17 mmHg (95%CI - 5.29, - 1.04), P < 0.01; and mean arterial blood pressure (MAP) MD - 7.19 mmHg (95%CI - 9.06, - 5.32), P < 0.0001. Office pulse pressure and resting heart rate was not significantly reduced, neither were 24-h or day-time ambulatory blood pressures (SBP, DBP). Night-time blood pressures, however, were significantly reduced with SBP MD - 4.28 mmHg (95%CI - 7.88, - 0.67), P = 0.02, and DBP MD - 2.22 mmHg (95%CI - 3.55, - 0.88), P < 0.01. IRT does lower SBP, DBP and MAP office and night-time ambulatory SBP and DBP, but not 24-h mean ambulatory blood pressures in people with hypertension.