背景肝脓肿是一个重要的健康问题,需要及时诊断和适当的管理。自发性肝脓肿是印度住院的常见原因,特别是在北部。通过分析人口统计,症状,放射学发现,实验室参数,和治疗结果,这项研究将为增进对肝脓肿的理解和管理提供有价值的见解。目的和目标评估人口统计,临床,实验室,三级护理中心住院肝脓肿患者的放射学参数和治疗方案。方法回顾性分析我院住院1年的150例肝脓肿患者的前瞻性资料。关于人口特征的数据,临床表现,病因学,放射学发现,实验室调查,管理策略,并收集治疗结果.采用描述性统计和相关统计检验进行数据分析。结果研究人群平均年龄为40.28±12.72岁,男性优势(136(90.7%))。阿米巴脓肿(94例(62.7%))最常见。肝肿大(144(96%)),发烧(140(93.3%)),腹痛(136(90.7%)),最常见的症状是厌食症(118例(78.7%))。超声检查显示孤立性脓肿(99(66%))比多发性脓肿(24(16%))更常见,主要位于右叶(128(85.3%))。实验室调查显示121例白细胞增多(80.7%),肝酶升高(95(63.3%)天冬氨酸转氨酶(AST)和80(53.3%)丙氨酸转氨酶(ALT)),133例碱性磷酸酶(ALP)升高(88.7%),和低白蛋白水平(138(92%))在相当比例的患者。单次针头抽吸(95(63.3%)),经皮引流(36(24%)),手术干预(4例(2.7%))是主要治疗方式.血清白蛋白水平(p<0.001)和ALP(p<0.001)显著低,分别,住院时间≥10天的患者。结论本研究提供了对肝脓肿患者的临床和实验室参数以及管理策略的见解。这些发现突出了不同的临床表现,不同的病因,以及放射成像和实验室检查在诊断和管理中的重要性。根据患者的情况量身定制的治疗策略对于优化结果至关重要。
Background Liver abscesses are a significant health concern, necessitating prompt diagnosis and appropriate management. Spontaneous liver abscesses are a frequent reason for hospitalizations in India, particularly in the northern part. By analyzing demographics, symptoms, radiological findings, laboratory parameters, and treatment outcomes, this study will contribute valuable insights to enhance the understanding and management of liver abscesses. Aims and objective To evaluate demographic, clinical, laboratory, and radiological parameters and management options in hospitalized patients with liver abscesses at a tertiary care center. Methods This study retrospectively analyzed prospectively collected data from 150 patients diagnosed with liver abscesses who were admitted to our ward for one year. Data on demographic characteristics, clinical presentation, etiology, radiological findings, laboratory investigations, management strategies, and treatment outcomes were collected. Descriptive statistics and relevant statistical tests were employed for data analysis. Results The study population had a mean age of 40.28±12.72 years, with a male preponderance (136 (90.7%)). Amoebic abscesses (94 (62.7%)) were the most common. Hepatomegaly (144 (96%)), fever (140 (93.3%)), abdominal pain (136 (90.7%)), and anorexia (118 (78.7%)) were the most common symptoms. Ultrasonography revealed solitary abscesses (99 (66%)) to be more common than multiple abscesses (24 (16%)), with a predominant location in the right lobe (128 (85.3%)). Laboratory investigations showed leukocytosis in 121 (80.7%), elevated liver enzymes (95 (63.3%) aspartate aminotransferase (AST) and 80 (53.3%) alanine transaminase (ALT)), elevated alkaline phosphatase (ALP) in 133 (88.7%), and low albumin levels (138 (92%)) in a significant proportion of patients. Single-time needle aspiration (95 (63.3%)), percutaneous drain (36 (24%)), and surgical intervention (4 (2.7%)) were the primary treatment modalities. Serum albumin level (p<0.001) and ALP (p<0.001) were significantly low and high, respectively, in patients with hospital stays ≥10 days. Conclusions This study provides insights into patients with liver abscesses\' clinical and laboratory parameters and management strategies. The findings highlight the diverse clinical presentation, varied etiologies, and the importance of radiological imaging and laboratory investigations in diagnosis and management. Tailored treatment strategies based on the patient\'s condition are crucial for optimizing outcomes.