未经批准:世界人口在不断增长。据估计,世界上一半的人口来自亚洲大陆,主要来自中国和印度。人口过剩可能会导致许多社会问题以及栖息地的变化。因此,需要采取生育控制措施来控制这种增长。然而,在过去的50-60年里,避孕领域没有任何改善。然而,免疫避孕疫苗是一个新兴领域,它可能是下一个千年现有避孕方式的唯一替代品。性传播感染(STIs)很常见,它们的传播率逐年增加。因为抗生素是这种感染的主要治疗方法,人类的抵抗力增加了;因此,对性传播感染有有效的抗生素治疗现在是一个令人担忧的问题。现在需要针对性传播感染的疫苗。人们认为蛋白质组学领域的进步,免疫组学,代谢组学,和其他组学将有助于成功开发疫苗。
UNASSIGNED:收集和回顾有关免疫避孕和性传播疾病/感染疫苗最新进展的文献。
未经评估:可靠的科学数据库,比如PubMedCentral,PubMed,Scopus,科学直接,和护目镜学者,被咨询过。收集了载有关于避孕疫苗设计的靶向抗原/免疫原和性传播感染疫苗开发进展的重要信息的出版物,并列出了表格,并根据每个研究的主题进行了细节分析。
UNASSIGNED:对生育具有特定作用的重要抗原因其避孕性质而被广泛研究。此外,筛选最佳抗原的进展,根据它们的抗原性,以及它们如何引发长时间的免疫反应也进行了研究。性传播感染的群体免疫和梅毒疫苗开发的进展,淋病,和单纯疱疹病毒也在这篇综述中进行了研究和列表。获得了关于性传播感染疫苗的广泛知识。
UNASSIGNED:这项广泛的综述旨在为疫苗学中的活跃研究人员提供见解,免疫学,和生殖生物学。不同性传播感染疫苗开发的进展可以作为一份有益的报告来收集。
UNASSIGNED: The world population is continuously growing. It has been estimated that half of the world\'s population is from the Asian continent, mainly from China and India. Overpopulation may lead to many societal problems as well as to changes in the habitat. Birth control measures are thus needed to control this growth. However, for the last 50-60 years, there have not been any improvements in the field of contraception. Nevertheless, the immunocontraceptive vaccine is an emerging field, and it might be the only replacement for the existing mode of contraception for the next millennium. Sexually transmitted infections (STIs) are frequent, and their transmission rate increases yearly. As antibiotics are the prevailing treatment for this kind of infections, resistance in humans has increased; therefore, having effective antibiotic treatments for STIs is now a concern. Vaccines against STIs are now needed. It is thought that the improvements in the fields of proteomics, immunomics, metabolomics, and other omics will help in the successful development of vaccines.
UNASSIGNED: To collect and review the literature about recent advancements in
immunocontraception and vaccines against sexually transmitted diseases/infections.
UNASSIGNED: Reliable scientific databases, such as PubMed Central, PubMed, Scopus, Science Direct, and Goggle Scholar, were consulted. Publications bearing important information on targeted antigens/immunogens for contraceptive vaccine design and advancements in vaccine development for STIs were gathered and tabulated, and details were analyzed as per the theme of each study.
UNASSIGNED: Important antigens that have a specific role in fertility have been studied extensively for their contraceptive nature. Additionally, the advancements in the screening for the best antigens, according to their antigenic nature and how they elicit immune responses for an extended period were also studied. Herd immunity for STIs and advancements in the development of vaccines for syphilis, gonorrhea, and herpes simplex virus were also studied and tabulated in this review. An extensive knowledge on STIs vaccines was gained.
UNASSIGNED: This extensive review is aimed to provide insights for active researchers in vaccinology, immunology, and reproductive biology. Advancements in the development of vaccines for different STIs can be gathered as a wholesome report.