背景:对影响自杀意念过渡到自杀未遂或自杀意念缓解的因素了解甚少。尽管对自杀意念的危险因素进行了大量研究,没有大规模的基于人群的纵向研究专门招募有自杀意念的人,来研究向自杀未遂或自杀意念恢复的关键过渡的潜在机制.没有心理上的纵向数据,行为,自杀企图的社会决定因素和自杀意念的缓解,我们不太可能看到在预防自杀方面取得重大进展。
目的:LifeTrack项目是一项基于人群的纵向队列研究,旨在确定预测自杀意念向自杀未遂过渡或自杀意念缓解的关键可改变风险和保护因素。我们将使用经过验证和有效的措施来评估理论上的风险和保护因素,以识别反映自杀意念严重程度变化的不同轨迹,并在三年内过渡到自杀未遂。
方法:一项为期三年的前瞻性基于人群的纵向队列研究将对最初报告自杀意念的澳大利亚普通人群中的成年人进行(n=842)。资格标准包括最近的自杀意念(过去30天),18岁或以上,生活在澳大利亚,英语流利。那些在过去30天内自杀未遂或无法参加长期研究的人将被排除在外。参与者将被要求完成与精神病理学相关的在线评估,认知,心理因素,社会因素,心理健康治疗的使用,和环境暴露在基线和每六个月在这三年期间。每年间隔一周的每日测量爆发(生态瞬时评估)也将捕获自杀意念的短期波动,感知到的负担,受挫的归属感,自杀能力,和痛苦。
结论:这项研究旨在为有自杀意念的人确定新的和量身定制的治疗方法的潜在目标,并改善自杀预防计划的目标。即使目前治疗的适度改善也可能导致自杀企图和死亡人数的大幅减少。
背景:澳大利亚新西兰临床试验注册标识符:ACTRN12623000433606。
The factors that influence transition from suicidal
ideation to a suicide attempt or remission of suicidal thoughts are poorly understood. Despite an abundance of research on risk factors for suicidal ideation, no large-scale longitudinal population-based studies have specifically recruited people with suicidal
ideation to examine the mechanisms underlying critical transitions to either suicide attempt or recovery from suicidal
ideation. Without longitudinal data on the psychological, behavioural, and social determinants of suicide attempt and the remission of suicidal ideation, we are unlikely to see major gains in the prevention of suicide.
The LifeTrack Project is a population-based longitudinal cohort study that aims to identify key modifiable risk and protective factors that predict the transition from suicidal ideation to suicide attempt or remission of suicidal
ideation. We will assess theory-informed risk and protective factors using validated and efficient measures to identify distinct trajectories reflecting changes in severity of suicidal ideation and transition to suicide attempt over three years.
A three-year prospective population-based longitudinal cohort study will be conducted with adults from the general Australian population who initially report suicidal ideation (n = 842). Eligibility criteria include recent suicidal
ideation (past 30 days), aged 18 years or older, living in Australia and fluent in English. Those with a suicide attempt in past 30 days or who are unable to participate in a long-term study will be excluded. Participants will be asked to complete online assessments related to psychopathology, cognition, psychological factors, social factors, mental health treatment use, and environmental exposures at baseline and every six months during this three-year period. One week of daily measurement bursts (ecological momentary assessments) at yearly intervals will also capture short-term fluctuations in suicidal ideation, perceived burdensomeness, thwarted belongingness, capability for suicide, and distress.
This study is intended to identify potential targets for novel and tailored therapies for people experiencing suicidal ideation and improve targeting of suicide prevention programs. Even modest improvements in current treatments may lead to important reductions in suicide attempts and deaths.
Australian New Zealand Clinical Trials Registry identifier: ACTRN12623000433606.