未经证实:建议对中度/重度特发性羊水过多进行产前胎儿监测,但对轻度特发性羊水过多不建议。这项研究的目的是确定轻度特发性羊水过多的妊娠是否会增加宫内胎儿死亡(IUFD)的风险。
UNASSIGNED:检查了大学医学中心2016年至2021年的病历和羊水体积超声数据。有胎儿异常的怀孕,胎儿感染,等免疫接种,多胎妊娠,孕妇糖尿病和羊水过少被排除.正常羊水体积定义为羊水指数(AFI)<24cm,与轻度特发性羊水过多相比,AFI≥24.0cm-29.9cm,和中度/重度羊水过多,即AFI≥30cm。
未经证实:在符合纳入研究标准的12,725名患者中,有249例特发性羊水过多(n=249),与IUFD(aOR)增加的3.27(CI1.50-7.15)相关,NICU入院(aOR1.28,CI0.96-1.70),5分钟APGAR得分小于7(aOR2.16,CI1.52-3.07),与正常羊水量(AFV)相比,胎龄婴儿(LGA)大(aOR4.04,CI2.83-5.78)。在轻度羊水过多组中(249名羊水过多妇女中n=204),与正常AFV组的12,476例妊娠相比,IUFD(AOR3.38,CI1.46-7.82),NICU入院(aOR1.19,CI0.87-1.64),5分钟APGAR评分小于7(aOR1.68,CI1.10-2.55)和LGA(aOR3.87,CI2.59-5.78)。在中度/重度羊水过多组(n=45)中,与正常AFV组相比,IUFD(aOR2.78,CI0.38-20.29)或NICU入院(aOR1.74,CI0.93-3.26)的几率没有增加,但5分钟APGAR评分小于7(aOR4.94,CI2.57-9.53)和LGA胎儿(aOR4.80,CI2.26-10.22)的几率增加.
未经证实:妊娠合并轻度特发性羊水过多的患者发生IUFD的几率增加。应建议患者增加与特发性羊水过多相关的不良妊娠结局的几率。在那些患有轻度特发性羊水过多的孕妇中,产前胎儿监测应考虑。
UNASSIGNED: Antenatal fetal surveillance has been recommended for moderate/severe idiopathic polyhydramnios but not for mild idiopathic polyhydramnios. The purpose of this study is to determine if pregnancies with mild idiopathic polyhydramnios have an increased risk for an intrauterine fetal demise (
IUFD).
UNASSIGNED: Medical records and amniotic fluid volume ultrasound data from 2016 to 2021 at a university medical center were examined. Pregnancies with fetal anomalies, fetal infection, isoimmunization, multiple gestation, maternal diabetes and oligohydramnios were excluded. Normal amniotic fluid volume was defined as an amniotic fluid index (AFI) <24 cm which was compared to mild idiopathic polyhydramnios, AFI of ≥24.0 cm-29.9 cm, and moderate/severe polyhydramnios which is an AFI ≥30 cm.
UNASSIGNED: Of 12,725 patients meeting inclusion study criteria, there were 249 with idiopathic polyhydramnios (n = 249) which was associated with an increased odds of
IUFD (aOR) of 3.27 (CI 1.50-7.15), NICU admission (aOR 1.28, CI 0.96-1.70), 5-minute APGAR score less than 7 (aOR 2.16, CI 1.52-3.07), and large for gestational age infant (LGA) (aOR 4.04, CI 2.83-5.78) compared to normal amniotic fluid volume (AFV). In the mild polyhydramnios group (n = 204, out of the 249 women with polyhydramnios) compared to the 12,476 pregnancies with normal AFV group,
IUFD (aOR 3.38, CI 1.46-7.82), NICU admission (aOR 1.19, CI 0.87-1.64), 5-minute APGAR score less than 7 (aOR 1.68, CI 1.10-2.55) and LGA (aOR 3.87, CI 2.59-5.78). In moderate/severe polyhydramnios group (n = 45) compared to the normal AFV group, there was no increased odds of
IUFD (aOR 2.78, CI 0.38-20.29) or NICU admission (aOR 1.74, CI 0.93-3.26) but an increased odds for a 5-minute APGAR score less than 7 (aOR 4.94, CI 2.57-9.53) and LGA fetus (aOR 4.80, CI 2.26-10.22).
UNASSIGNED: There is an increased odds of
IUFD in pregnancies complicated by mild idiopathic polyhydramnios. Patients should be counseled on an increased odds of adverse pregnancy outcomes associated with idiopathic polyhydramnios, and in those pregnancies with mild idiopathic polyhydramnios, antenatal fetal surveillance should be considered.