■ILC在大脑中发挥重要作用,gut,gut还有肺.研究人员正在尝试使用ILC建立关于脑-肠-肺轴的研究框架。然而,尚未有人进行文献计量学分析来总结研究结果。在这项研究中,我们利用文献计量学来分析大脑中ILC的新兴趋势和焦点区域,肠,还有肺.旨在为今后脑-肠-肺轴的研究提供参考。
■为了对大脑领域的ILC进行全面的文献计量分析,肠,和肺,我们使用了HistCite等软件,VOSviewer,和城市空间。我们的分析集中在各个方面,包括出版物的数量,国家,作者,期刊,共同引用的文件,和关键词。这种方法使我们能够获得对这些特定领域围绕ILC的研究前景的宝贵见解。
■共有8411篇关于大脑领域ILC的文章或评论,肠,和肺都包括在内。自2003年以来,已发表的文章数量一直呈上升趋势。共有来自99个国家的45279位作者为这些文章做出了贡献。美国的出版物数量最多(n=3044),被引用的文章最多(TGCS=210776)。在这一领域发表的前三名作者是大卫·阿蒂斯,MarcoColonna和AndrewNJMcKenzie.《免疫》杂志是研究人员最权威的选择。该领域的主要研究热点包括NK细胞,ILC2,肿瘤免疫,多发性硬化症,炎症性肠病,气道炎症,RORγT,和免疫疗法。近年来,癌症和肿瘤微环境已经成为热门关键词,特别是免疫疗法,PD-1相关方向,表明研究重点的潜在转移。
■欧美国家在开展ILC研究方面一直举足轻重,虽然中国出版了大量出版物,其影响仍然有限。肿瘤可能会成为该领域的下一个焦点。大脑和肺之间的联系和调节尚未完全理解,进一步研究ILC在脑-肺轴中的作用是必要的。
ILCs play important roles in the brain, gut, and lungs. Researchers are attempting to establish a research framework on the brain-gut-lung axis using
ILCs. However, no one has yet conducted a bibliometric analysis to summarize the findings. In this study, we utilized bibliometrics to analyze the emerging trends and focal areas of
ILCs in the brain, intestine, and lung. We aim to provide references for future research on the brain-gut-lung axis.
To conduct a comprehensive bibliometric analysis on
ILCs in the fields of brain, intestine, and lung, we utilized software such as HistCite, VOSviewer, and CiteSpace. Our analysis focused on various aspects, including the number of publications, countries, authors, journals, co-cited documents, and keywords. This approach allowed us to gain valuable insights into the research landscape surrounding
ILCs in these specific fields.
A total of 8411 articles or reviews on ILCs in the fields of brain, intestine, and lung were included. The number of published articles has shown a consistent upward trend since 2003. A total of 45279 authors from 99 countries have contributed to these articles. The United States has the highest number of publications (n=3044) and the most cited articles (TGCS=210776). The top three published authors in this field are David Artis, Marco Colonna and Andrew NJ McKenzie. The journal Immunity is the most authoritative choice for researchers. The main research focuses in this field include NK cell, ILC2, tumor immunity, multiple sclerosis, inflammatory bowel disease, airway inflammation, RORγT, and immunotherapy. In recent years, cancer and tumor microenvironment have emerged as hot keywords, particularly immunotherapy, PD-1 related directions, indicating a potential shift in research focus.
European and American countries have been pivotal in conducting research on ILCs, while China has produced a significant number of publications, its impact is still limited. Tumors are likely to emerge as the next focal points in this field. The connection and regulation between the brain and the lung are not yet fully understood, and further investigation is necessary to explore the role of ILCs in the brain-lung axis.