UASSIGNED:手术是临床治疗高血压脑出血的主要方法。传统开颅手术面临着手术时间长的缺点,术中容易对患者造成二次伤害,手术后容易感染,不利于患者的康复。目前,迫切需要找到手术方案,能及时清除血肿,保护脑组织,在临床上有效减少手术创伤。
未经评估:我们医院的病例数据库,回顾性分析2018年2月至2021年10月采用软通道微创穿刺引流术治疗高血压脑出血患者的临床资料。对患者进行疗效评估,和血清C反应蛋白(CRP)的变化,肿瘤坏死因子-α(TNF-α),白细胞介素-6(IL-6),同型半胱氨酸(Hcy),内皮素(ET),术前加压素(AVP)水平,手术后3天,术后7天进行分析。收集临床资料,采用Logistic回归分析预后因素。
未经评估:最后,根据纳入和排除标准,选择126例患者作为研讨对象。其中,痊愈24例(19.05%),显效47例(37.30%),34例(26.98%)有效,无效11例(8.73%),死亡10例(7.94%)。总有效率为83.33%。116例(92.06%)血肿基本清除。血肿清除时间平均为(7.82±1.63)天。术后颅内感染2例(1.59%),术后再出血5例(3.97%)。平均住院时间(34.16±16.59)天。血清CRP,TNF-α,IL-6Hcy,ET,所有患者术后第3天和第7天的AVP水平均低于术前,术后第7天低于术后第3天(p<0.05)。术前格拉斯哥昏迷量表(GCS)评分的差异,出血量,心室破裂,复杂的脑疝,预后良好组与预后不良组之间的手术发作时间差异有统计学意义(p<0.05)。术前GCS评分,出血量,心室破裂,复杂的脑疝,和手术时间均为影响患者预后的独立因素(p<0.05)。
UNASSIGNED:软通道微创穿刺引流治疗HICH效果显著,这有利于血肿的完全清除,缩短住院时间,同时调节各种细胞因子的平衡和稳定性,改善患者预后。术前GCS评分,出血量,破裂进入心室,复杂的脑疝,发病至手术时间是影响患者预后的独立因素。
UNASSIGNED: Surgery is the main method for the clinical treatment of hypertensive cerebral hemorrhage. Traditional craniotomy faces the disadvantages of the long operation time, easy to cause secondary injury to patients during the operation, and prone to infection after the operation, which is not conducive to the rehabilitation of patients. At present, it is urgent to find a surgical scheme, which can clear hematoma in time, protect brain tissue, and effectively reduce surgical trauma in the clinic.
UNASSIGNED: The case database of our hospital was consulted, and the clinical data of patients with hypertensive intracerebral hemorrhage (HICH) treated with soft channel minimally invasive puncture and drainage from February 2018 to October 2021 were retrospectively analyzed. Patients were evaluated for efficacy, and the changes in serum C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), homocysteine (Hcy), endothelin (ET), and vasopressin (AVP) levels before surgery, 3 days after surgery, and 7 days after surgery were analyzed. Clinical data were collected and Logistic regression was used to analyze the prognostic factors.
UNASSIGNED: Finally, according to the inclusion and exclusion criteria, 126 patients were selected as the research object. Among them, there were 24 cases (19.05%) of recovery, 47 cases (37.30%) of markedly effective, 34 cases (26.98%) of effective, 11 cases (8.73%) of ineffective, and 10 cases (7.94%) of death. The total effective rate was 83.33%. The hematoma was basically removed in 116 cases (92.06%). The average evacuation time of hematoma was (7.82 ± 1.63) days. Post-operative intracranial infection occurred in 2 cases (1.59%) and post-operative rebleeding occurred in 5 cases (3.97%). The average hospital stay was (34.16 ± 16.59) days. Serum CRP, TNF-α, IL-6, Hcy, ET, and AVP levels of all patients on the third and seventh days after surgery were lower than those before surgery, and those on the seventh day after surgery were lower than those on the third day after surgery (p < 0.05). The differences in pre-operative Glasgow Coma Scale (GCS) score, bleeding volume, ventricular rupture, complicated cerebral hernia, and attack time to surgery between the good prognosis group and the bad prognosis group were statistically significant (p < 0.05). Pre-operative GCS score, bleeding volume, ventricular rupture, complicated cerebral hernia, and onset time to surgery were all independent factors that affect the prognosis of patients (p < 0.05).
UNASSIGNED: Soft-channel minimally invasive puncture and drainage treatment of HICH has a significant effect, which is conducive to the complete removal of hematoma, reducing hospitalization time, while adjusting the balance and stability of various cytokines, and improving patient prognosis. Pre-operative GCS score, bleeding volume, rupture into the ventricle, complicated cerebral hernia, and time from onset to operation are all independent factors that affect the prognosis of patients.