饲料和食品工业有针对性地使用碳水化合物来创造平衡和具有成本效益的饮食,在不同物种的碳水化合物消化和吸收方面产生了大量的研究。具体来说,这项研究使我们进行了更大的观察,确定了不同物种肠道钠依赖性葡萄糖吸收的不同组织,以前没有整理和审查过。因此,这篇综述将比较不同物种肠道中钠依赖性葡萄糖转运的动力学分离,我们称之为同质或异质系统。例如,猪遵循具有高亲和力的钠依赖性葡萄糖转运的异质系统,空肠中的超低容量(Ha/sLc),和高亲和力,回肠中的超高容量(Ha/sHc)。这是通过对每个片段有贡献的多个钠依赖性葡萄糖转运蛋白实现的。相比之下,罗非鱼具有高亲和力的同质系统,整个肠道的高容量(Ha/Hc)。此外,我们首先报道了从脊椎动物到无脊椎动物的跨物种的葡萄糖转运蛋白模式。最后,简要介绍了其他动力学转运系统,以说明钠依赖性葡萄糖转运蛋白组织的可能贡献/调节。总的来说,我们提出了一个关于肠道葡萄糖吸收组织的新观点。
The targeted use of carbohydrates by feed and food industries to create balanced and cost-effective diets has generated a tremendous amount of research in carbohydrate digestion and absorption in different species. Specifically, this research has led us to a larger observation that identified different organizations of intestinal sodium-dependent glucose absorption across species, which has not been previously collated and reviewed. Thus, this review will compare the kinetic segregation of sodium-dependent glucose transport across the intestine of different species, which we have termed either
homogeneous or heterogeneous systems. For instance, the pig follows a heterogeneous system of sodium-dependent glucose transport with a high-affinity, super-low-capacity (Ha/sLc) in the jejunum, and a high-affinity, super-high-capacity (Ha/sHc) in the ileum. This is achieved by multiple sodium-dependent glucose transporters contributing to each segment. In contrast, tilapia have a homogenous system characterized by high-affinity, high-capacity (Ha/Hc) throughout the intestine. Additionally, we are the first to report glucose transporter patterns across species presented from vertebrates to invertebrates. Finally, other kinetic transport systems are briefly covered to illustrate possible contributions/modulations to sodium-dependent glucose transporter organization. Overall, we present a new perspective on the organization of glucose absorption along the intestinal tract.