组织细胞肉瘤是一种极其罕见的疾病,很难诊断和治疗,常导致预后不良。这里,我们提供了一个病例报告,详述了一名37岁孕妇中罕见的HS发生情况,该孕妇最初表现为左肩疼痛,心悸,妊娠20周时出现生产性咳嗽。她进行了诊断评估,包括不同的成像模式,如胸部X光,CT扫描,MRI。影像学显示纵隔肿块大,肾上腺广泛受累,肺,和淋巴结。HS的最终诊断是基于病理和形态学特征,免疫组织化学报告起着关键作用。在我们的案例中,通过病理评估和免疫组织化学证实了HS的诊断,从锁骨上淋巴结活检获得CD68阳性结果。一个由血液学家-肿瘤学家等医学专家组成的医院委员会,病理学家,肺病学家,产科医生被召集在一起集体评估病例。病人接受了化疗,缓解了她的症状并保持了病情。根据委员会的建议,尽管胎儿健康,产科超声检查正常,经患者及其家人同意,决定终止妊娠.尽管化疗后有初步改善,病人的病情恶化了,需要插管。可悲的是,初次入院两个月后,患者因严重并发症去世。在这个案例报告中,我们对患者的影像学报告进行了文献回顾和回顾。由于患者怀孕并且HS并不常见,重要的是要强调这个案例是独一无二的,值得分享。
Histiocytic sarcoma is an extremely rare disease that\'s hard to diagnose and treat, often leading to a poor prognosis. Here, we present a case report detailing a rare occurrence of HS in a 37-year-old pregnant woman who first presented with left shoulder pain, palpitations, and a productive cough at 20 weeks of gestation. Her diagnostic evaluations were performed, including different imaging modalities such as chest X-rays, CT scans, and MRI. Imaging revealed a large mediastinal mass with extensive involvement of the adrenal glands, lungs, and lymph nodes. The definitive diagnosis of HS is based on pathological and morphological features, and the immunohistochemistry report plays a key role. In our case, the diagnosis of HS was confirmed through pathological evaluation and immunohistochemistry, with a positive CD68 result obtained from a supraclavicular lymph node biopsy. A hospital committee comprising medical specialists like hematologists-oncologists, pathologists, pulmonologists, and obstetricians was brought together to assess the case collectively. The patient received chemotherapy, which alleviated her symptoms and maintained her condition. Based on the committee\'s recommendations, despite a healthy fetus and normal obstetric sonograms, the decision was made to terminate the pregnancy with the consent of the patient and her family. Despite initial improvement postchemotherapy, the patient\'s condition worsened, necessitating intubation. Tragically, two months after the initial admission, the patient passed away due to severe complications. In this case report, we provide a literature review and review of the patient\'s imaging reports. Since the patient is pregnant and HS is uncommon, it\'s important to highlight that this case is unique and worth sharing.