■肺栓塞(PE)是全髋关节置换术(THA)后发病率的众所周知的原因。通过药物和围手术期干预措施,已经投入了相当大的努力来减少PE的发生。尽管如此,这些策略在降低与肺栓塞事件相关的发生率和总死亡率方面的有效性仍存在争议.因此,识别有风险的患者越来越重要。
■我们利用了2016年至2021年国家手术质量改进计划(NSQIP)参与者使用文件(PUF)数据库中的数据。所有术前参数随后用卡方分析,有意义的进行逻辑回归检验。
■一项研究检查了235,393例全髋关节置换术患者中影响肺栓塞(PE)患病率的因素。单变量分析确定PE和女性之间的显著关联,糖尿病,吸烟,呼吸困难,CHF,COPD,高血压(HT),出血性疾病,播散性癌症,使用类固醇,和功能健康状况。多变量分析显示男性是保护性的,而COPD,高血压,和播散性癌症增加PE风险。值得注意的是,吸烟似乎是保护性的。PE患者的手术复诊率较高(41.7%vs.2.2%),但30天死亡率相似(0.2%与0.04%),尽管死亡率的比值比并不显著。
■我们的研究结果表明,某些患者特征,如COPD和转移性恶性肿瘤,显着影响PE发展的可能性。
UNASSIGNED: Pulmonary embolism (PE) is a well-known contributor to morbidity after total hip arthroplasty (THA). Considerable efforts have been invested in reducing PE occurrence through pharmacological and perioperative interventions. Nonetheless, the effectiveness of these strategies in reducing the incidence and overall mortality associated with pulmonary embolism events remains a matter of debate. Therefore, identifying risky patients has been gaining importance.
UNASSIGNED: We utilised data from the National Surgical Quality Improvement Program (NSQIP) participant usage file (PUF) database spanning the years 2016 to 2021. All preoperative parameters were analysed with chi-square afterwards, meaningful ones were run with logistic regression test.
UNASSIGNED: A study examined factors influencing pulmonary embolism (PE) prevalence in 235,393 total hip arthroplasty patients. Univariate analysis identified significant associations between PE and female gender, diabetes, smoking, dyspnea, CHF, COPD, hypertension (HT), bleeding disorders, disseminated cancer, steroid use, and functional health status. Multivariate analysis revealed male gender as protective, while COPD, hypertension, and disseminated cancer increased PE risk. Notably, smoking appeared protective. PE patients had higher return-to-operation rates (41.7% vs. 2.2%) but similar 30-day mortality (0.2% vs. 0.04%), though mortality\'s odds ratio was not significant.
UNASSIGNED: Our findings suggest that certain patient characteristics, such as COPD and metastatic malignancy, significantly influence the likelihood of PE development.