Hip prosthesis

髋关节假体
  • 文章类型: Journal Article
    本贝叶斯网络荟萃分析比较了全髋关节置换术(THA)中不同类型的聚乙烯衬里的磨损穿透率(mm/年)和翻修率。比较的衬里类型是交联的超高分子量聚乙烯(CPE/UHMWPE),维生素E注入高度交联聚乙烯(HXLPE-VEPE),改性交联聚乙烯(MXLPE),高交联聚乙烯(HXLPE),交联聚乙烯(XLPE)。本研究是根据PRISMA扩展声明进行的,用于报告结合医疗保健干预的网络荟萃分析的系统评价。2024年6月,PubMed,Scopus,Embase,谷歌学者,并访问了Cochrane数据库。从2000年1月起设定了时间限制。访问了比较两种或更多种类型的用于THA的聚乙烯衬里的所有研究。仅包括明确说明衬里性质的研究。收集了来自60项研究(37,352THA)的数据。56%的患者为女性。患者平均年龄为60.0±6.6岁,平均BMI为27.5±2.0kg/m2。平均随访时间为81.6±44.4个月。组间在基线处发现可比性。在大约7年的随访中,THA中的XLPE和HXLPE衬里与最低的磨损穿透率(毫米/年)和最低的翻修率相关。
    The present Bayesian network meta-analysis compared different types of polyethylene liners in total hip arthroplasty (THA) in terms of wear penetration (mm/year) and rate of revision. The type of liners compared were the crosslinked ultra-high molecular weight polyethylene (CPE/UHMWPE), Vitamin E infused highly cross-linked polyethylene (HXLPE-VEPE), modified cross-linked polyethylene (MXLPE), highly cross-linked polyethylene (HXLPE), Cross-linked polyethylene (XLPE). This study was conducted according to the PRISMA extension statement for reporting systematic reviews incorporating network meta-analyses of healthcare interventions. In June 2024, PubMed, Scopus, Embase, Google Scholar, and Cochrane databases were accessed. A time constraint was set from January 2000. All investigations which compared two or more types of polyethylene liners for THA were accessed. Only studies that clearly stated the nature of the liner were included. Data from 60 studies (37,352 THAs) were collected. 56% of patients were women. The mean age of patients was 60.0 ± 6.6 years, the mean BMI was 27.5 ± 2.0 kg/m2. The mean length of follow-up was 81.6 ± 44.4 months. Comparability was found at baseline between groups. XLPE and HXLPE liners in THA are associated with the lowest wear penetration (mm/year) and the lowest revision rate at approximately 7 years of follow-up.
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  • 文章类型: Journal Article
    背景:人工关节感染(PJI)的两阶段翻修(TSR)后的再感染率为7.9%至14%。许多因素,包括窦道,与此过程后的再感染有关。这项研究旨在描述窦道的存在是否会增加TSR后的再感染率,并调查TSR后再感染的其他潜在危险因素。
    方法:我们进行了一项病例对照研究,回顾性回顾了2002年至2022年因假体髋关节感染而接受TSR的患者。病例组包括TSR后发生再感染的患者,而对照组由没有经历再感染的患者组成。根据基于Delphi的国际共识标准定义PJI和TSR后的再感染。患者人口统计学,既往病史,临床表现,实验室结果,阶段之间的间隔,收集微生物培养结果。单因素分析用于评估窦道对再感染的影响,并确定TSR后再感染的其他危险因素。
    结果:6例TSR后再感染患者为病例组,32例未再感染患者为对照组。两组之间窦道患者的百分比存在显着差异(病例组为67%,对照组为19%,p=0.031,OR=8.7)。两组在第一阶段翻修期间收获的滑液和滑膜培养阳性的患者百分比也存在显着差异(病例组为100%,对照组为50%,p=0.030)。此外,病例组患者在第二阶段修订前的C反应蛋白(CRP)水平明显高于对照组患者(8.80mg/L与2.36mg/L,p=0.005),尽管所有患者的CRP水平正常。
    结论:我们的研究表明,窦道的存在可显著增加TSR术后再感染的风险。第一阶段修订期间的阳性培养和第二阶段修订之前升高的CRP水平也可能增加TSR后再感染的风险。需要更大样本量的进一步研究。
    背景:回顾性注册。
    BACKGROUND: Reinfection rates after two-stage revision (TSR) for prosthetic joint infection (PJI) range from 7.9 to 14%. Many factors, including sinus tracts, are associated with reinfection after this procedure. This study aimed to delineate whether the presence of sinus tract could increase reinfection rate after TSR and to investigate other potential risk factors for reinfection after TSR.
    METHODS: We conducted a case-control study by retrospectively reviewing patients who underwent TSR for prosthetic hip joint infection from 2002 to 2022. The case group included patients who developed reinfection after TSR, while the control group consisted of patients who did not experience reinfection. PJI and reinfection after TSR were defined based on Delphi-based international consensus criteria. Patient demographics, past medical history, clinical manifestations, laboratory results, interval between stages, microbiological culture results were collected. Univariate analyses were utilized to assess the effect of sinus tract on reinfection and to identify other risk factors for reinfection after TSR.
    RESULTS: Six patients with reinfection after TSR were included as the case group and 32 patients without reinfection were in the control group. Significant difference was observed in percentage of patients with sinus tracts between the two groups (67% in the case group versus 19% in the control group, p = 0.031, OR = 8.7). Significant difference was also found in percentage of patients with positive cultures of synovial fluid and synovium harvested during the first-stage revision between the two groups (100% in the case group versus 50% in the control group, p = 0.030). Additionally, patients in the case group had a significantly higher C-reactive protein (CRP) level prior to the second stage revision than that of patients in the control group (8.80 mg/L versus 2.36 mg/L, p = 0.005), despite normal CRP levels in all patients.
    CONCLUSIONS: Our study revealed that the presence of sinus tracts could significantly increase risk of postoperative reinfection after TSR. Positive cultures during the first stage revision and elevated CRP level prior to the second stage revision could also increase the risk of reinfection after TSR. Further studies with a larger sample size are required.
    BACKGROUND: Retrospectively registered.
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  • 文章类型: Journal Article
    背景:人工关节感染(PJI)是顽固性的,难以治疗的感染和关节置换术的严重并发症。因此,有必要开发新的有效治疗策略,和高临床相关性的动物模型是必需的。这项研究旨在为哥廷根小型猪的髋关节置换术制定详细的手术方案,并制定彻底的验尸采样方案,为创建小型猪PJI模型铺平道路。
    方法:三只成年雌性哥廷根小型猪接受了插入髋关节半髋关节置换术的手术,用髋关节前路.手术后,对小型猪进行每日临床评估和步态评分。进行全面的验尸分析,评估宏观病变,微生物学,滑液分析和组织学。
    结果:该研究导致了第一只哥廷根小型猪进行了髋关节半髋关节置换术,并确定了在小型猪中插入髋关节假体时的几个意识点,尤其是关节脱位的风险很高。一只小型猪发生了自发性PJI,显示免疫细胞到达骨-假体界面处的细菌的能力受损。
    结论:本研究提供了手术技术和死后采样的详细描述,并验证了人工髋关节置换小型猪模型在PJI未来实验建模中的适用性。
    BACKGROUND: Prosthetic joint infections (PJI) are recalcitrant, hard-to-treat infections and severe complications of joint arthroplasty. Therefore, there is a need to develop new effective treatment strategies, and animal models of high clinical relevance are needed. This study aimed to develop a detailed surgical protocol for hip hemiarthroplasty in Göttingen minipigs and a thorough post-mortem sampling protocol to pave the way for creating a minipig PJI model.
    METHODS: Three adult female Göttingen minipigs underwent surgery with insertion of a hip hemiarthroplasty, using the anterior approach to the hip joint. After surgery the minipigs were followed closely with daily clinical evaluation and gait scoring. Comprehensive post-mortem analyses were performed with evaluation of macroscopic lesions, microbiology, synovial fluid analysis and histology.
    RESULTS: The study resulted in the first Göttingen minipig with hip hemiarthroplasty and identified several points of awareness when inserting a hip prosthesis in minipigs, especially the high risk of joint dislocation. A spontaneous PJI occurred in one of the minipigs, revealing an impaired ability of the immune cells to reach the bacteria at the bone-prosthesis interface.
    CONCLUSIONS: The present study provides a detailed description of surgical technique and post-mortem sampling and validates the suitability of the hip hemiarthroplasty minipig model for future experimental modeling of PJI.
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  • 文章类型: Journal Article
    目的:股骨假体周围骨折(PFF)是全髋关节置换术(THA)的重要并发症。尽管生物力学研究表明,制备股骨管的技术起着一定的作用,很少有临床研究报道这可能如何影响骨折风险。这项研究比较了无水泥THA中使用齿形器械进行压实和拉削之间的断裂风险。
    方法:使用从一家高容量医院的质量登记册中前瞻性收集的数据。包括使用Corail茎(DePuySynthes)的所有主要关节置换术。所有发生在术后前90天内的股骨骨折均纳入分析。我们确定了压实与拉削相比维持PFF的相对风险,并对混杂因素进行了调整(性别,年龄组,BMI,和使用带领茎)使用多变量泊松回归。
    结果:在2009年11月至2023年5月之间进行的6,788例主要THA可用于分析。66%为女性,平均年龄为65.0岁。手术后的前90天发生了129例(1.9%)骨折,压实组92例(2.3%),拉削组37例(1.3%)。与拉削组相比,压实组的未调整相对骨折风险为1.82(95%置信区间[CI]1.25-2.66),而调整后的相对危险度为1.70(CI1.10-2.70)。
    结论:在手术后90天内,与拉伤(2.3%对1.3%)相比,压实与更多的假体周围骨折相关。
    OBJECTIVE:  Periprosthetic femoral fracture (PFF) is a significant complication of total hip arthroplasty (THA). Although biomechanical studies have indicated that the technique by which the femoral canal is prepared plays a role, few clinical studies have reported on how this might affect the fracture risk. This study compares the fracture risk between compaction and broaching with toothed instruments in cementless THA.
    METHODS: Prospectively collected data from the quality register of a high-volume hospital was used. All primary arthroplasties using the Corail stem (DePuy Synthes) were included. All femoral fractures occurring within the first 90 days after the operation were included in the analysis. We determined the relative risk of sustaining PFF with compaction compared with broaching and adjusted for confounders (sex, age group, BMI, and use of a collared stem) using multivariable Poisson regression.
    RESULTS:  6,788 primary THAs performed between November 2009 and May 2023 were available for analysis. 66% were women and the mean age was 65.0 years. 129 (1.9%) fractures occurred during the first 90 days after the operation, 92 (2.3%) in the compaction group and 37 (1.3%) in the broaching group. The unadjusted relative risk of fracture in the compaction group compared with the broaching group was 1.82 (95% confidence interval [CI] 1.25-2.66), whereas the adjusted relative risk was 1.70 (CI 1.10-2.70).
    CONCLUSIONS: Compaction was associated with more periprosthetic fractures than broaching (2.3% versus 1.3%) within 90 days after surgery.
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    文章类型: English Abstract
    BACKGROUND: total hip arthroplasty (THA) is one of the most performed surgeries worldwide, with high satisfaction rates. The orientation of the acetabular component has a direct impact on the risk of dislocation, recently with the support of robotic surgery the margin of error in implant placement has decreased; however, the conventional technique even without fluoroscopic support continues to have satisfactory results within the safety zone.
    METHODS: retrospective, cross-sectional, descriptive case series of patients treated with THA at Hospital General Xoco between 2022 and 2024. Degrees of anteversion and inclination were measured with Widmer\'s method on postoperative radiographs.
    RESULTS: the radiographs of 113 patients were studied, 80 female and 33 male, with a mean age of 63.2 ± 13.01 years (95% CI: 60.6-65.4), a mean inclination of 42.2° ± 8.1° (95% CI: 40.7-43.2) and anteversion of 14.3° ± 8.5° (95% CI: 12.5-15.4); 76% of the population was within Lewinnek safe zone; by etiology: osteoarthrosis 74%, sequelae of dysplasia 68% and intracapsular fracture 82%; difference between the values of the affected side: left 65%, right 83%, of 3.9° and 4.7°/6.4o and 9° in relation to the overall values of the population.
    CONCLUSIONS: in our population undergoing THA, without the use of robotic technique or support of imaging studies, anteversion and inclination figures were recorded within the Lewinnek safety parameters with a conventional method.
    UNASSIGNED: la artroplastía total de cadera (ATC) es una de las cirugías más realizadas a nivel mundial, con altos porcentajes de satisfacción. La orientación del componente acetabular tiene impacto directo en el riesgo de luxación; recientemente, con el apoyo de la cirugía robótica, el margen de error en la colocación de los implantes ha disminuido; sin embargo, la técnica convencional, incluso sin apoyo fluoroscópico, continúa teniendo resultados satisfactorios dentro de la zona de seguridad.
    UNASSIGNED: serie de casos retrospectiva, transversal y descriptiva, de pacientes tratados con ATC en Hospital General Xoco entre 2022 y 2024. Se midieron los grados de anteversión e inclinación con el método de Widmer en las radiografías postoperatorias.
    RESULTS: se estudiaron las radiografías de 113 pacientes, 80 mujeres y 33 hombres, con edad media de 63.2 ± 13.01 años (IC95%: 60.6-65.4), se obtuvo una inclinación media de 42.2° ± 8.1° (IC95%: 40.7-43.2) y anteversión de 14.3° ± 8.5° (IC95% 12.5-15.4); 76% de la población se encontraba dentro de la zona segura de Lewinnek; por etiología: osteoartrosis 74%, secuelas de displasia 68% y fractura intracapsular 82%; diferencia entre los valores del lado afectado: izquierdo 65%, derecho 83%, de 3.9° y 4.7°/6.4° y 9° en relación con los valores globales de la población.
    UNASSIGNED: en nuestra población sometida a ATC, sin uso de técnica robótica o apoyo de estudios de imagen, se registraron cifras de anteversión e inclinación dentro de los parámetros de seguridad de Lewinnek con un método convencional.
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  • 文章类型: Journal Article
    全髋关节置换术(THA)最常见的适应症是髋关节骨关节炎。插入THA是为了改善功能,减轻疼痛,提高生活质量。结果总体上是好的,90-95%的患者感到满意。然而,有与THA相关的风险,患者必须充分了解情况。在考虑THA之前,必须完成非手术治疗,因为手术的需要经常被推迟。患者可以期望快速动员并在一年内恢复到接近习惯性的身体活动水平。在丹麦,95%的人在5年后有THA,76%的人在25年后有THA。
    The most frequent indication for total hip arthroplasty (THA) is hip osteoarthritis. THA is inserted to improve function, reduce pain, and improve quality of life. Results are generally good, and 90-95% of the patients are satisfied. However, there are risks associated with THA, and patients must be well informed. Before THA is considered, non-surgical treatment must be completed, as the need for surgery often is postponed. Patients can expect rapid mobilisation and a return to a near-habitual level of physical activity within a year. In Denmark, 95% have their THA after five years and 76% after 25 years.
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  • 文章类型: Journal Article
    背景:这项研究使用有限元分析(FEA)比较了双球形金属增强物(BA)和楔形小梁-金属增强物(TA)在不同髋臼缺损重建模型中的生物力学稳定性,从而解释了这种新颖的双球形增强在复杂髋关节翻修中的应用价值。
    方法:三种不同的髋臼缺损骨盆模型,起源于三个具有不同类型严重髋臼缺损的代表性患者(PoproskIIC,IIIA,和IIIB)进行了构建,并用BA和TA技术进行了重建。基于有限元分析模型,重建植入物的位移,骨植入物的相对位移,研究了静态载荷下的半骨盆vonMises应力。
    结果:BA获得了较小的重建系统位移,骨植入物的相对位移较小,在所有PeproskyIIC中,骨盆vonMises应力低于TA,IIIA,和IIIB缺陷重建。
    结论:FEA结果表明,BA在严重髋臼缺损重建中可以获得良好的生物力学稳定性。该技术是复杂髋关节翻修的可靠方法。
    BACKGROUND: This study used finite element analysis (FEA) to compare the biomechanical stability of bispherical metal augment (BA) and wedge-shaped trabecular-metal augment (TA) in different acetabular defect reconstruction models, thereby explaining the application value of this novel bispherical augment in complex hip revision.
    METHODS: Three different acetabular defect pelvis models originating from three representative patients with different types of severe acetabular defects (Paprosky IIC, IIIA, and IIIB) were constructed and reconstruction with BA and TA technique was simulated. Based on the FEA models, the displacement of reconstruction implants, relative displacement of bone implants, and hemi-pelvic von Mises stress were investigated under static loads.
    RESULTS: BA acquired smaller reconstruction system displacement, less relative displacement of bone implants, and lower pelvic von Mises stress than TA in all Paprosky IIC, IIIA, and IIIB defect reconstructions.
    CONCLUSIONS: The FEA results show that BA could acquire favourable biomechanical stability in severe acetabular defect reconstruction. This technique is a reliable method in complex hip revision.
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  • 文章类型: Journal Article
    背景:手术方式影响全髋关节置换术(THA)后的结果和恢复,和方法可能会影响茎的定位。与微创手术的一般概念相反,直接前路(DAA)导致更多的术中失血。因此,这项研究的目的是比较三种手术方法中的茎定位和隐性失血(HBL):微创DAA,OrthopadischeChirurgieMunchen(OCM),和传统的后外侧入路(PLA)。
    方法:共有201例患者使用DAA进行首次非水泥THA,OCM,和PLA被纳入研究。一般人口统计数据,阀杆对齐,并对失血量进行了评估。具体比较测量包括股骨颈前倾,股骨干前倾,茎在冠状面和矢状面上的对齐,近端和远端髓质比率,和股骨偏移。通过计算术中失血量(IBL)来测量失血量,可见失血(VBL),隐性失血(HBL)
    结果:年龄没有显著差异,性别,身体质量指数,术前诊断,或股骨Dorr分类。与PLA相比,DAA和OCM的平均手术时间更长(P<0.01)。DAA组IBL最高,PLA组最低(P<0.05)。术后茎前倾在各组间有显著差异,DAA表现出最大的前倾差异(P<0.05)。茎冠状排列没有差异。然而,DAA和OCM矢状面有更多的外翻和内翻植入物。DAA和OCM组的股骨偏移减少效果较差(P<0.05)。DAA和OCM的近端和远端髓质比率较低(P<0.05)。与PLA相比,DAA和OCM中的HBL显著降低(P<0.05)。
    结论:DAA和OCM等微创方法在肌肉和软组织保存方面具有优势,与常规PLA相比,导致HBL降低。然而,这些方法在股骨柄定位和更长的手术时间方面存在挑战.
    BACKGROUND: The surgical approach impacts the outcomes and recovery after total hip arthroplasty (THA), and approaches may affect the stem positioning. Contrary to the general concept of minimally invasive surgery, the direct anterior approach (DAA) results in more intraoperative blood loss. Therefore, the objective of this study was to compare stem positioning and hidden blood loss (HBL) among three surgical approaches: the minimally invasive DAA, Orthopadische Chirurgie Munchen (OCM), and the traditional posterolateral approach (PLA).
    METHODS: A total of 201 patients undergoing their first non-cemented THA using the DAA, OCM, and PLA were included in the study. General demographic data, stem alignment, and blood loss were evaluated. Specific comparison measurements included femoral neck anteversion, femoral stem anteversion, alignment of the stem in coronal and sagittal planes, proximal and distal medullary ratios, and femoral offset. Blood loss was measured by calculating Intraoperative Blood Loss ( IBL), visible blood loss (VBL), and hidden blood loss (HBL).
    RESULTS: There were no significant differences in age, gender, body mass index, preoperative diagnosis, or femoral Dorr classification among the three groups. The mean surgical time was longer for the DAA and OCM compared to the PLA (P < 0.01). IBL was highest in the DAA group and lowest in the PLA (P < 0.05). Postoperative stem anteversion were significantly different among the groups, with the DAA showing the greatest anteversion difference (P < 0.05). There was no difference in the stem coronal alignment. However, there were more valgus and varus implants in the sagittal plane for the DAA and OCM. The femoral offset reduction was less optimal in the DAA and OCM groups (P < 0.05). The proximal and distal medullary ratios were lower in the DAA and OCM (P < 0.05). HBL was significantly lower in the DAA and OCM compared to the PLA (P < 0.05).
    CONCLUSIONS: Minimally invasive approaches such as DAA and OCM offer advantages in muscle and soft tissue preservation, leading to reduced HBL compared to the conventional PLA. However, these approaches present challenges in femoral stem positioning and longer surgical times.
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  • 文章类型: Case Reports
    方法:一名53岁男子在左髋关节表面置换术(HRA)后出现13毫米的腿长差异,导致疼痛和不平衡。还注意到对侧髋关节的晚期骨关节炎。患者强烈喜欢HRA而不是全髋关节置换术。足够的剩余骨量和重新覆盖对侧髋关节的能力允许使用2个HRA解决。
    结论:这是已知的第一个HRA与随后的HRA的修订。假设有足够的骨量和精确的植入物定位,表面置换提出了一种可行的方法来克服复杂的解剖畸形和提高流动性。
    METHODS: A 53-year-old man presented with a 13-mm leg length discrepancy following left hip resurfacing arthroplasty (HRA), resulting in pain and imbalance. Advanced osteoarthritis of the contralateral hip was also noted. The patient strongly preferred HRA over total hip arthroplasty. Adequate remaining bone stock and the ability to resurface the contralateral hip allowed for resolution with 2 HRAs.
    CONCLUSIONS: This is the first known revision of a HRA with a subsequent HRA. Assuming sufficient bone stock and precise implant positioning, resurfacing presents a feasible methodology to overcome complex anatomical deformities and improve mobility.
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