目的:社会人口统计学因素已被证明会影响手术结局。然而,这些因素对接受细胞减灭术(CRS)和腹腔加热化疗(HIPEC)的患者的影响尚不清楚.本研究旨在评估社会人口统计学因素对CRS/HIPEC患者的影响。
方法:对三级中心接受CRS/HIPEC的成年患者进行评估。收集并分析围手术期变量。国家数据库也用于评估接受CRS/HIPEC的患者。
结果:有90例患者接受了CRS/HIPEC(32%非白人)。术后并发症差异无统计学意义,逗留时间,或基于种族的出院处置(白色与非白人患者),社会经济地位(SES),或保险类型。在全国范围内,我们发现,与非西班牙裔白人患者相比,黑人和西班牙裔患者接受CRS/HIPEC的可能性较低(黑人:比值比[OR]:0.60,[置信区间{CI}:0.39-0.94];西班牙裔:OR:0.52,[CI:0.28-0.98]).然而,不同种族/民族的术后并发症无显著差异.
结论:包括种族在内的社会人口统计学因素,SES,在我们的单一机构接受CRS/HIPEC的患者中,保险状态并不影响术后结局.在国家层面,与白人患者相比,黑人和西班牙裔患者的CRS/HIPEC发生率较低。
OBJECTIVE: Sociodemographic factors have been shown to impact surgical outcomes. However, the effects of these factors on patients undergoing cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) are not well known. This study aims to evaluate the impact of sociodemographic factors on patients undergoing CRS/HIPEC.
METHODS: Adult patients at a tertiary center who underwent CRS/HIPEC were evaluated. Perioperative variables were collected and analyzed. A national database was also used to evaluate patients undergoing CRS/HIPEC.
RESULTS: There were 90 patients who underwent CRS/HIPEC (32% non-White). There was no statistically significant difference in postoperative complications, length of stay, or discharge disposition based upon race (white vs. non-White patients), socioeconomic status (SES), or insurance type. Nationally, we found that Black and Hispanic patients were less likely to undergo CRS/HIPEC than Non-Hispanic white patients (Black: odds ratio [OR]: 0.60, [confidence interval {CI}: 0.39-0.94]; Hispanic: OR: 0.52, [CI: 0.28-0.98]). However, there were no significant differences in postoperative complications based upon race/ethnicity.
CONCLUSIONS: Sociodemographic factors including race, SES, and insurance status did not impact postoperative outcomes in patients undergoing CRS/HIPEC at our single institution. On a national level, Black and Hispanic patients underwent CRS/HIPEC at lower rates compared to white patients.