Health care-seeking behaviour

寻求医疗保健的行为
  • 文章类型: Journal Article
    背景:对疟疾快速诊断测试(MRDT)的需求有很好的了解,疟疾寻求医疗保健的行为,社区成员之间的毒品使用对疟疾控制工作至关重要。本研究的目的是评估MRDT的需求(使用和/或要求),寻求医疗保健的行为,和吸毒,以及相关因素,在Ebonyi州患有发烧或疟疾样疾病的农村社区成员(包括儿童和成人)中,尼日利亚。
    方法:在10月1日至11月7日之间进行了横断面家庭调查,2018年,在18个农村地理集群中。使用结构化的面试官管理的问卷收集数据。使用汇总统计进行描述性分析。相关因素(社会人口,知识和意见水平)使用双变量和多变量二项逻辑回归进行评估,而这些因素的总体影响则使用Stata中的“后估计检验”命令进行评估。
    结果:共有1310名5岁以下儿童和2329名5岁及以上儿童和成人(不包括孕妇)(总共3639名)参加了这项研究。在1310名5岁以下儿童中:521名(39.8%)接受MRDT,其中82名(15.7%)的护理人员要求MRDT;931名(71.1%)在当天/第二天向公共/私营部门提供者(不包括传统从业人员/小贩)寻求护理;495名(37.8%)在政府初级保健中心寻求护理,744(56.8%)向专利药供应商(PMV)寻求护理;136(10.4%)向传统从业者寻求护理;1020(77.9%)服用了ACTs(=88.2%,服用抗疟疾药物的人的1020/1156)。一般来说,在2329名5岁及以上儿童和成人(不包括孕妇)中,数值分别较低.MRDT需求和寻求护理行为的最重要的总体预测指标是受访者女性户主对疟疾和疟疾诊断的知识和意见水平。
    结论:在Ebonyi州患有发烧或疟疾样疾病的农村社区成员中,尼日利亚,虽然大多数人没有接受MRDT或诊断测试,并向PMV寻求护理,大多数人服用抗疟疾药物,主要是ACTs。需要采取干预措施,提高女性户主对疟疾和疟疾诊断的认识和意见。
    BACKGROUND: A good understanding of the demand for malaria rapid diagnostic test (MRDT), malaria health care-seeking behavior, and drug use among community members is crucial to malaria control efforts. The aim of this study was to assess the demand (use and/or request) for MRDT, health care-seeking behavior, and drug use, as well as associated factors, among rural community members (both children and adults) with fever or malaria-like illness in Ebonyi state, Nigeria.
    METHODS: A cross-sectional household survey was conducted between October 1st and November 7th, 2018, in 18 rural geographical clusters. Data was collected using a structured interviewer-administered questionnaire. Descriptive analysis was done using summary statistics. Associated factors (socio-demographic, knowledge and opinion level) were assessed using bivariate and multivariate binomial logistic regressions while the overall effects of these factors were assessed using the \"postestimation test\" command in Stata.
    RESULTS: A total of 1310 children under 5 years of age and 2329 children ages 5 years and above and adults (excluding pregnant women) (3639 overall) participated in the study. Among the 1310 children under 5 years of age: 521 (39.8%) received MRDT of which the caregivers of 82 (15.7%) requested for the MRDT; 931 (71.1%) sought care with public/private sector providers (excluding traditional practitioners/drug hawkers) the same/next day; 495 (37.8%) sought care at government primary health centres, 744 (56.8%) sought care with the patent medicine vendors (PMVs); 136 (10.4%) sought care with traditional practitioners; 1020 (77.9%) took ACTs (=88.2%, 1020/1156 of those who took anti-malarial drugs). Generally, lower values were respectively recorded among the 2329 children ages 5 years and above and adults (excluding pregnant women). The most important overarching predictor of the demand for MRDT and care-seeking behaviour was the knowledge and opinion level of respondent female heads of households about malaria and malaria diagnosis.
    CONCLUSIONS: Among the rural community members with fever or malaria-like illness in Ebonyi state, Nigeria, while majority did not receive MRDT or diagnostic testing, and sought care with the PMVs, most took anti-malaria drugs, and mostly ACTs. Interventions are needed to improve the knowledge and opinion of the female heads of households about malaria and malaria diagnosis.
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  • 文章类型: Journal Article
    研究表明,年轻人更有可能使用急诊科治疗“临床上不必要的”问题,使用紧急救护车的类似证据有限。媒体刻画描绘了年轻人受到“便利”的激励,但是很少有研究探索他们寻求帮助行为的原因。
    对临床医生认为不必要使用紧急救护车的16名年轻人(18-30岁)进行定性访谈,急诊科或紧急全科医生预约。数据分析由解释性现象学分析提供信息。
    许多相互关联的因素促成了参与者的决策。他们担心症状的严重性,有时由于不良的心理健康或生活压力导致的应对能力下降而加剧。他们希望别人帮助他们做出决定,有时鼓励紧急接触。他们希望避免影响现有的日常承诺,包括工作或学习。他们对不同的医疗服务有强烈的看法,有时是基于对持续健康问题缺乏解决的挫折感。便利性没有被确定为一个重要因素,尽管如果不考虑上下文,可以从这个角度来解释一些行动。
    年轻人为了方便而“临床上不必要”使用紧急和紧急护理。他们的决定需要根据他们的经验的复杂性来理解,包括在做出与健康相关的决定时缺乏信心,降低了应对能力和对维持正常日常生活的关注。
    Studies have identified young adults as more likely to use emergency departments for \'clinically unnecessary\' problems, with limited similar evidence for emergency ambulance use. Media portrayals depict young adults as motivated by \'convenience\', but little research has explored the reasons for their help-seeking behaviour.
    Qualitative interviews with 16 young adults (18-30) considered by clinicians to have made unnecessary use of emergency ambulance, emergency department or an urgent GP appointment. Data analysis was informed by interpretive phenomenological analysis.
    A number of interrelated factors contributed to participants\' decisions. They were anxious about the seriousness of their symptoms, sometimes exacerbated by reduced coping capacity due to poor mental health or life stresses. They looked to others to facilitate their decision making, who sometimes encouraged urgent contact. They wanted to avoid impact on existing day-to-day commitments including work or study. They had strong views about different health services, sometimes based on frustration with lack of resolution of on-going health problems. Convenience was not identified as a significant factor, although some actions could be interpreted in this light if the context was not considered.
    Young adults make \'clinically unnecessary\' use of urgent and emergency care for more than convenience. Their decisions need to be understood in relation to the complexity of their experience, including lack of confidence in making health-related decisions, lowered coping capacity and concern to maintain normal daily life.
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  • 文章类型: Journal Article
    背景:病例管理是疟疾控制的主要策略之一。这项研究旨在评估简单的疟疾病例管理的经济成本,并探讨寻求健康的行为对这些成本的影响。
    方法:知识,2017年3月,对Mazan-Loreto15个社区的680户家庭进行了态度和实践(KAP)调查,然后于2017年9月对过去3个月中确诊为无并发症疟疾的161名个人进行了社会经济调查。每次发作的总费用由两个提供者估计(卫生部,MoH)和患者观点。直接成本是使用标准成本估算程序估算的,虽然间接成本考虑了患者的收入损失,就每月最低工资而言,因疾病而替代劳工和同伴。敏感性分析评估了每次发作的平均成本的不确定性。
    结果:KAP调查显示,大多数患有疟疾的人(79.3%)去医疗机构进行诊断和治疗,2.7%的人从社区卫生工作者那里获得了这些服务,8%的人去了药店或在家接受自我治疗。马赞地区每集的平均总成本为161美元。从提供者的角度来看,每次发作的费用为30.85美元,而从患者的角度来看,估计每次发作的费用为131美元。每个恶性疟原虫发作的平均费用(180美元)高于每个间日疟原虫发作的平均费用(156美元),这是由于恶性疟原虫感染患者(22.2天)的工作时间比间日疟原虫感染患者(17.0天)的工作时间更长。疟疾诊断延迟(症状发作48小时后)与因疾病而失去的工作时间有关(调整后的平均比率1.8;95%CI1.3,2.6)。每个疟疾发作的平均成本对疟疾造成的生产力损失成本的不确定性最敏感。
    结论:尽管卫生部提供了免费的疟疾病例管理,寻求护理的延误,简单的疟疾的费用主要由家庭承担。这些成本并没有被社会很好地认识到,这种疾病的重大财务影响在公共政策规划中经常被低估。
    BACKGROUND: Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking behaviours on those costs.
    METHODS: A knowledge, attitudes and practices (KAP) survey was applied to 680 households of fifteen communities in Mazan-Loreto in March 2017, then a socio-economic survey was conducted in September 2017 among 161 individuals with confirmed uncomplicated malaria in the past 3 months. Total costs per episode were estimated from both provider (Ministry of Health, MoH) and patient perspectives. Direct costs were estimated using a standard costing estimation procedure, while the indirect costs considered the loss of incomes among patients, substitute labourers and companions due to illness in terms of the monthly minimum wage. Sensitivity analysis evaluated the uncertainty of the average cost per episode.
    RESULTS: The KAP survey showed that most individuals (79.3%) that had malaria went to a health facility for a diagnosis and treatment, 2.7% received those services from community health workers, and 8% went to a drugstore or were self-treated at home. The average total cost per episode in the Mazan district was US$ 161. The cost from the provider\'s perspective was US$ 30.85 per episode while from the patient\'s perspective the estimated cost was US$ 131 per episode. The average costs per Plasmodium falciparum episode (US$ 180) were higher than those per Plasmodium vivax episode (US$ 156) due to longer time lost from work by patients with P. falciparum infections (22.2 days) than by patients with P. vivax infections (17.0 days). The delayed malaria diagnosis (after 48 h of the onset of symptoms) was associated with the time lost from work due to illness (adjusted mean ratio 1.8; 95% CI 1.3, 2.6). The average cost per malaria episode was most sensitive to the uncertainty around the lost productivity cost due to malaria.
    CONCLUSIONS: Despite the provision of free malaria case management by MoH, there is delay in seeking care and the costs of uncomplicated malaria are mainly borne by the families. These costs are not well perceived by the society and the substantial financial impact of the disease can be frequently undervalued in public policy planning.
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  • 文章类型: Journal Article
    背景:适当寻求医疗保健的做法对于减少严重和危及生命的儿童疾病很重要。在夏尔镇,人们对母亲在儿童疾病上寻求医疗保健的行为知之甚少。
    目的:评估夏尔镇有5岁以下儿童的母亲的现代健康寻求行为和相关因素。
    方法:研究背景是夏尔镇,西北提格雷,埃塞俄比亚。
    方法:进行了一项基于社区的横断面研究,通过系统随机抽样技术对504对母婴进行了访谈。数据是通过采访者管理的半结构化问卷收集的。数据被编码,输入,使用EPIDATA版本3.1进行清理和编辑,并导出到社会科学统计包(SPSS)版本22.0进行分析。为了确定重要的变量,采用二元逻辑回归。在多变量逻辑回归中,在95%CI(置信区间)具有p值0.05的变量被认为具有统计学意义。
    结果:在这项研究中,约76.2%(72.1%,80%)的母亲寻求现代医疗保健。在P值为0.05的多变量逻辑回归分析中,年龄≥28岁的照顾者(AOR[调整后的比值比]:1.65;95%CI[1.02,2.68]),中学及以上教育水平(AOR:0.44;95%CI[0.23,0.86]),儿童每日喂养8次(AOR:2.77;95%CI[1.75,4.38])和感知的疾病严重程度(AOR:2;95%CI[1.07,3.82])在统计学上与现代寻求医疗保健行为相关.
    结论:建议通过信息在社区层面加强医疗保健服务,教育和沟通/行为改变策略,以改善母亲寻求医疗保健的行为。
    BACKGROUND: The practice of appropriate health care-seeking is important to reduce severe and life-threatening childhood illnesses. In Shire town, little is known about the mother\'s health care-seeking behaviour on childhood illness.
    OBJECTIVE: To assess modern health-seeking behaviour and associated factors of mothers having under 5-years old children in Shire town.
    METHODS: The study setting was Shire town, northwest Tigray, Ethiopia.
    METHODS: A community-based cross-sectional study was conducted to interview 504 mother-child pairs by systematic random sampling technique. Data were collected through interviewer-administered semi-structured questionnaires. Data were coded, entered, cleaned and edited using EPIDATA version 3.1 and export to Statistical Package for Social Science (SPSS) Version 22.0 for analysis. To identify the significant variables, binary logistic regression was employed. Variables with p-value 0.05 at 95% CI (confidence interval) in multivariate logistic regression were considered statistically significant.
    RESULTS: In this study, around 76.2% (72.1, 80) of mothers sought modern health care. In a multivariate logistic regression analysis at a p-value of 0.05, caregivers with age of ≥ 28 years (AOR [adjusted odds ratios]: 1.65; 95% CI [1.02, 2.68]), educational level of secondary school and above (AOR: 0.44; 95% CI [0.23, 0.86]), child feeding per day 8 times (AOR: 2.77; 95% CI [1.75, 4.38]) and perceived severity of illness (AOR: 2; 95% CI [1.07, 3.82]) were statistically associated with modern health care-seeking behaviour.
    CONCLUSIONS: Strengthen healthcare services is recommended at the community level through information, education and communication/behavioural change strategies to improve the mother\'s health care-seeking behaviour.
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  • 文章类型: Journal Article
    目标:在中国,患者通常在高级医院寻求医疗保健,这导致了医疗费用的上升和医院的超负荷。一些研究表明,卫生系统是影响个人寻求医疗保健行为的重要因素;然而,这种关联尚未得到深入研究。因此,我们研究了卫生系统(在医疗保险报销和卫生劳动力之间的相互作用方面)对寻求医疗保健行为的影响。
    方法:根据2008年和2013年的全国调查数据,我们将选择医疗保健提供者的个人水平数据(我们的寻求医疗保健行为指数)与县级数据联系起来。卫生劳动力和健康保险。然后,我们构建了一个多层次的多项逻辑模型,以检查健康保险报销(以平均报销率[ARR]为索引)和县级医院和初级医疗机构(PHCs)的卫生劳动力(每1000人的注册医生人数)的影响选择住院护理提供者。
    结果:县医院ARR的增加与访问此类医院的更大概率相关(相对风险比[RRR]=1.23),这种积极影响在医生密度较高的县医院更大(RRR=2.76)。PHC的ARR值较高与去市政和高级医院的概率降低73%相关;当考虑PHC的医师密度时,ARR值增加与更低的概率相关(RRR=0.09)。
    结论:增加健康保险报销和卫生人力对于改善医疗服务的获取,从而改善寻求医疗服务的行为是必要的。因此,全面的卫生体制改革是必要的。
    OBJECTIVE: In China, patients generally seek health care at high-level hospitals, which is leading to escalating medical costs and overloaded hospitals. Some studies have suggested that the health system is an important factor influencing individuals\' health care-seeking behaviour; however, this association has not been studied in much depth. We therefore examined the impact of the health system (in terms of the interaction between health insurance reimbursement and health workforce) on health care-seeking behaviour.
    METHODS: Drawing on national survey data from 2008 and 2013, we linked individual-level data on choice of health care providers (our index of health care-seeking behaviour) with county-level data on the health workforce and health insurance. We then constructed a multilevel multinomial logistic model to examine the impacts of health insurance reimbursement (indexed as average reimbursement rate [ARR]) and the health workforce (number of registered physicians per 1000 population) at county hospitals and primary health care institutions (PHCs) on choice of inpatient care providers.
    RESULTS: Increases in ARR at county hospitals were associated with a greater probability of visiting such hospitals (relative risk ratio [RRR] = 1.23), and this positive impact was even greater in county hospitals with higher physician densities (RRR = 2.76). Greater ARR in PHCs was associated with a 73% lower probability of visiting municipal- and higher-level hospitals; increasing ARR was associated with an even lower probability when physician density in PHCs was considered (RRR = 0.09).
    CONCLUSIONS: Increases in the health insurance reimbursement and health workforce are necessary to improve health care access and thereby health care-seeking behaviour. Thus, comprehensive health system reform is necessary.
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  • 文章类型: Journal Article
    OBJECTIVE: To identify and describe reasons women do not seek health care for dysmenorrhea symptoms.
    BACKGROUND: Although dysmenorrhea is highly prevalent among women, can cause significant disruptions in their daily lives, and may increase their risk for future chronic pain conditions, few women seek health care for dysmenorrhea. A better understanding of why women do not seek health care is necessary to develop strategies that facilitate care seeking and optimal symptom management.
    METHODS: A qualitative descriptive design was used to guide the study and summarise text responses to an open-ended survey question.
    METHODS: Participants in an online survey study who had not sought health care for dysmenorrhea (N = 509) were asked to write about their reasons for not seeking care. Data were collected in January and February 2015. Participants\' text responses were analysed using qualitative content analysis.
    RESULTS: Nine categories of reasons were identified as follows: assuming symptoms are normal, preferring to self-manage symptoms, having limited resources, thinking providers would not offer help, being unaware of treatment options, considering symptoms to be tolerable, being wary of available treatments, feeling embarrassed or afraid to seek care and not seeking health care generally.
    CONCLUSIONS: Findings can guide the development of strategies to promote care seeking and inform policy and clinical practice to improve dysmenorrhea management.
    CONCLUSIONS: Findings underscore the need to provide routine screening for dysmenorrhea, avoid dismissing dysmenorrhea symptoms, initiate discussions and provide education about dysmenorrhea, provide treatments options based on evidence and women\'s preferences and raise public awareness of dysmenorrhea and its impact.
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  • 文章类型: Journal Article
    BACKGROUND: In India, migrant status, tribal affiliation and poverty render tribal migrants more vulnerable than any other group which leads to high treatment costs and the risk of low access to health care.
    OBJECTIVE: To examine treatment-seeking behaviour and out-of-pocket (OOP) expenditure on the treatment of childhood illnesses, with a focus on gender in a migrant tribal community in Bhubaneswar, eastern India.
    METHODS: A total of 175 households with a child aged 0-14 years and who had migrated within the last 12 years were selected from tribal-dominated slums. Data on health-seeking behaviour and expenditure on a recent illness in the youngest child were collected by interviewing mothers during October 2007 to March 2008.
    RESULTS: Of the 175 children, 78.8% had at least one episode of illness during the previous year. Of the total number of episodes, 71% had been treated and 61% of them had incurred OOP expenditure. A significantly lower proportion of episodes of illness in girls had been treated than in boys (P = 0.01) and incurred OOP expenditure (P = 0.05). Private health care was preferred and only 16.5% availed themselves of the government sources. About 89 and 87% of households of boys and girls, respectively, incurred OOP expenditure. A child\'s gender (female) (P = 0.05), mother\'s education (P = 0.002) and type of illness (P = 0.002) were significantly associated with total OOP expenditure.
    CONCLUSIONS: Further studies are warranted to address the low access to government health care and thereby reduce high OOP expenditure by tribal migrants on low incomes. Efforts are required to increase the ability of communities and health providers to identify and address the issues of gender and equity in health care along with a focus on culture-sensitive service provision.
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  • 文章类型: Journal Article
    背景:使用2013年在加拿大进行的国际初级保健质量和成本(QUALICOPC)调查,对加拿大人寻求身心健康问题的医疗保健行为进行了检查。
    方法:本研究使用了来自加拿大10个省759个实践的7260名患者的横断面患者经历调查,作为QUALICOPC研究的一部分。构建了响应式护理量表(RCS),以反映11种健康状况中寻求医疗保健行为的程度。使用几个患者特征作为自变量,进行了四次多元回归分析.
    结果:患者的自我报告表明,寻求医疗保健的行为存在性别差异,女性报告说,她们比男性更大程度地拜访了初级保健提供者,以解决身体和心理健康问题。总的来说,与身体健康问题相比,患者寻求心理健康问题的可能性较小。对男女来说,回归结果表明,年龄,疾病预防,在解释针对精神健康问题的求医行为时,对医生和慢性病的信任是重要因素.
    结论:本研究通过详细探索预测男性和女性寻求卫生保健行为差异的变量,证实了寻求卫生保健行为的性别差异,从而推动了先前的研究。与身体健康问题相比,这些变量更好地预测了寻求医疗保健的行为,以应对心理健康问题。可能反映出寻求精神保健的人之间存在更大的差异。这项研究通过确定那些更有可能从事寻求医疗保健行为的人以及预测寻求医疗保健的变量,对那些致力于改善医疗保健障碍的人具有启示意义。因此,那些没有获得初级保健的人可以成为目标,可以制定和实施政策来促进他们寻求保健的行为。
    BACKGROUND: Canadians\' health care-seeking behaviour for physical and mental health issues was examined using the international Quality and Cost of Primary Care (QUALICOPC) survey that was conducted in 2013 in Canada.
    METHODS: This study used the cross-sectional Patient Experiences Survey collected from 7260 patients in 759 practices across 10 Canadian provinces as part of the QUALICOPC study. A Responsive Care Scale (RCS) was constructed to reflect the degree of health care-seeking behaviour across 11 health conditions. Using several patient characteristics as independent variables, four multiple regression analyses were conducted.
    RESULTS: Patients\' self-reports indicated that there were gender differences in health care-seeking behaviour, with women reporting they visited their primary care provider to a greater extent than did men for both physical and mental health concerns. Overall, patients were less likely to seek care for mental health concerns in comparison to physical health concerns. For both women and men, the results of the regressions indicated that age, illness prevention, trust in physicians and chronic conditions were important factors when explaining health care-seeking behaviours for mental health concerns.
    CONCLUSIONS: This study confirms the gender differences in health care-seeking behaviour advances previous research by exploring in detail the variables predicting differences in health care-seeking behaviour for men and women. The variables were better predictors of health care-seeking behaviour in response to mental health concerns than physical health concerns, likely reflecting greater variation among those seeking mental health care. This study has implications for those working to improve barriers to health care access by identifying those more likely to engage in health care-seeking behaviours and the variables predicting health care-seeking. Consequently, those who are not accessing primary care can be targeted and policies can be developed and put in place to promote their health care-seeking behavior.
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  • 文章类型: Journal Article
    BACKGROUND: Late diagnosis of cancer may partly be explained by the fact that some patients do not seek health care promptly when experiencing an alarm symptom. Socioeconomic and demographic differences exist concerning knowledge and awareness of cancer alarm symptoms in the general population and socioeconomic differences are found in cancer incidence and survival. We therefore hypothesise that socioeconomic and demographic differences in health care-seeking behaviour are present among people with alarm symptoms.
    OBJECTIVE: To analyse associations between health care seeking and socioeconomic and demographic factors among people reporting cancer alarm symptoms.
    METHODS: A questionnaire survey comprising 20000 people aged >20 from the Danish population. The questionnaire concerned alarm symptoms of common cancers and subsequent health care seeking. Data on socioeconomic factors were obtained from Statistics Denmark.
    RESULTS: health care seeking and patient interval.
    RESULTS: A total of 26.1% of all subjects reported that they did not seek health care when having experienced an alarm symptom. Women-subjects aged >40, subjects living with a partner and subjects having a cancer diagnosis-were more likely to seek health care, whereas medium educational level was negatively associated with health care seeking. Further, women were more likely to seek health care within 1 month, whereas subjects out of the workforce were less likely to do so.
    CONCLUSIONS: Approximately three out of four subjects sought health care when having experienced an alarm symptom but 50% waited for at least 1 month. Some demographic factors were found to be associated with health care-seeking behaviour and the patient interval, whereas no consistent associations were found with regard to socioeconomics.
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  • 文章类型: Journal Article
    BACKGROUND: In acute myocardial infarction the risk of death and loss of myocardial tissue is at its highest during the first few hours. However, the process from symptom onset to the decision to seek medical care can take time. To comprehend patients\' pre-hospital delay, attention must be focused on the circumstances preceding the decision to seek medical care.
    OBJECTIVE: To add a deeper understanding of patients\' thoughts, feelings and actions that preceded the decision to seek medical care when afflicted by an acute myocardial infarction.
    METHODS: Fourteen men and women with a first or second acute myocardial infarction were interviewed individually in semi-structured interviews. Data were analysed by qualitative content analysis.
    RESULTS: Four themes were conceptualized: \'being incapacitated by fear, anguish and powerlessness\', \'being ashamed of oneself\', \'fear of losing a healthy identity\' and \'striving to avoid fear by not interacting with others\'. Patients were torn between feelings such as anguish, fear, shame and powerlessness. They made an effort to uphold their self-image as being a healthy person thus affected by an unrecognized discomfort. This combined with a struggle to protect others from involvement, strengthened the barriers to seeking care.
    CONCLUSIONS: The present study indicates that emotional reactions are important and influence patients\' pre-hospital behaviour. Being ashamed of oneself stood out as a novel finding. Emotions might be an important explanation of undesired and persisting patient delays. However, our findings have to and should be evaluated quantitatively. Such a study is in progress.
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