Head and Neck Surgery

头颈部手术
  • 文章类型: Journal Article
    目标:手术结果决定了国家排名,声誉,和资金,并且通常使用客观的手术风险计算器(SRC)进行评估。不考虑外科医生的评估。这项研究旨在确定外科医生或SRC是否更准确地预测结果。方法:这项前瞻性队列研究确定了外科医生在术前对患者风险的评估。患者的风险也使用SRC计算。将预测结果与患者结果进行比较,以评估外科医生或SRC是否更准确。结果:在纳入的101例患者中,37例(36.6%)经历了任何类型的并发症,18例(17.8%)经历了严重的并发症。吸烟导致总并发症发生率高2.49倍(P=.04)。与接受游离皮瓣重建[比值比(OR)0.9]或任何其他手术(OR0.26)相比,喉切除术患者的并发症发生率最高(P=.02)。外科医生和美国外科医生学会(ACS)工具在预测任何并发症的结果方面均表现不佳。受试者工作特征(ROC)曲线下面积(AUC)为0.51[95%置信区间(CI):0.39-0.62]和0.58(95%CI:0.47-0.70),分别,无统计学意义(P=0.34)。为了预测严重并发症的结果,外科医生和ACS工具的AUC分别为0.55(95%CI:0.41-0.69)和0.60(95%CI:0.46-0.74),分别,无统计学意义(P=0.58)。结论:经过验证的风险计算器和外科医生都不能准确预测围手术期风险。唯一有助于改善并发症预测的风险因素是术前吸烟,尽管年龄和手术类型也是重要的预测因素。因此,风险计算器可能不是评估医院绩效的适当指标。这些发现可以帮助指导术前咨询,并可能有助于开发更准确的预测工具,因为医疗保健领域继续将人工智能纳入手术计划。
    Objectives: Surgical outcomes determine national ranking, reputation, and funding, and are often assessed with objective surgical risk calculators (SRCs). Surgeons\' assessments are not considered. This study aims to determine if surgeons or SRCs are more accurate in predicting outcomes. Methods: This prospective cohort study identified a surgeon\'s assessment on a patient\'s risk preoperatively. The patient\'s risk was also calculated using the SRC. Predictions were compared to patient outcomes and to each other to assess whether surgeons or the SRC were more accurate. Results: Of the 101 patients included, 37 (36.6%) experienced a complication of any kind and 18 (17.8%) experienced a serious complication. Smoking resulted in a 2.49 times higher overall complication rate (P = .04). Laryngectomy patients experienced the highest rate of complications (P = .02) compared to those undergoing free flap reconstruction [odds ratio (OR) 0.9] or any other surgery (OR 0.26). Both surgeons and the American College of Surgeons (ACS) tool performed poorly on the prediction of the outcome of any complication, with a receiver operating characteristic (ROC) area under the curve (AUC) of 0.51 [95% confidence interval (CI): 0.39-0.62] and 0.58 (95% CI: 0.47-0.70), respectively, which was not statistically significant (P = .34). For the prediction of the outcome of serious complication, the AUC for surgeons and the ACS tool were 0.55 (95% CI: 0.41-0.69) and 0.60 (95% CI: 0.46-0.74), respectively, which was not statistically significant (P = .58). Conclusions: Neither validated risk calculators nor surgeons are accurate in predicting perioperative risk. The only risk factor that contributes to improving predictions for complications is preoperative smoking, although age and type of surgery are also significant predictors. Risk calculators may therefore not be appropriate metrics for assessing hospital performance. These findings can help guide preoperative counseling and may help in the development of more accurate predictive tools as the healthcare field continues to incorporate artificial intelligence into surgical planning.
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  • 文章类型: Journal Article
    在进行安全的甲状腺和甲状旁腺手术时,对颈部解剖结构及其最终异常的完整和精确知识至关重要。IV分支弓的胚胎遗传畸形可导致罕见的解剖学改变,称为非复发性喉下神经。其患病率在右旋分支的0.7%和左旋分支的0.04%之间变化。在这些情况下,喉下神经分支直接起源于颈迷走神经,没有钩住就进入喉部,右侧锁骨下动脉周围或左侧主动脉弓周围。喉返神经的存在具有挑战性,由于医源性神经损伤的风险增加,导致声音嘶哑,吞咽困难,声门梗阻,声带麻痹,和严重的气道损伤。我们介绍了一个58岁女性的案例。该患者因甲状腺右叶BethesdaIV结节入院。通过使用术中神经监测(IONM),外科医生术中检测到喉部非返神经。随后的计算机断层扫描扫描证实了从左主动脉弓分支的右锁骨下动脉异常,Lusoria动脉.在这种情况下,解剖变异代表了陷阱,在进行甲状腺手术时,必须准确了解颈部区域。诸如IONM的设备对于检测可能导致医源性损害的异常是有用的。
    Complete and precise knowledge of the neck anatomy and its eventual anomalies is crucial while performing a safe thyroid and parathyroid surgery. Embryo-genetic malformations of the IV branchial arch can lead to an uncommon anatomical alteration known as non-recurrent inferior laryngeal nerve. Its prevalence varies between 0.7% for the dextral branch and 0.04% for the sinistral. In these cases, the inferior laryngeal nerve branches originate directly from the cervical vagus nerve, entering the larynx without hooking, on the right side around the subclavian artery or on the left around the aortic arch. The presence of a non-recurrent laryngeal nerve is challenging, due to the increased risks of iatrogenic damage to the nerve, which results in hoarseness, dysphagia, glottal obstruction, vocal cords palsy, and serious airway impairment. We present the case of a 58-year-old woman. The patient was admitted to our department for a nodule classified as Bethesda IV in the right thyroid lobe. Through the use of intraoperative neuromonitoring (IONM), surgeons detected intraoperatively a non-recurrent laryngeal nerve. A subsequent computed tomography scan confirmed an anomalous right subclavian artery branching from the left aortic arch, the Lusoria Artery. Anatomical variants represent pitfalls in this case and an accurate knowledge of the neck region is imperative while performing thyroid surgery. Devices such as IONM are useful for detecting abnormalities that may lead to iatrogenic damages.
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  • 文章类型: Journal Article
    由于头部和颈部的解剖复杂性以及实验室和手术室(OR)之间的可变接近度,在冰冻切片分析(FSA)期间,外科医生和病理学家之间的有效沟通具有挑战性.这项概念验证研究调查了一种增强现实(AR)协议,该协议允许病理学家从实验室虚拟加入OR。使用三维扫描仪离体扫描头颈癌标本并上传到AR平台中。外科医生和病理学家在AR环境中讨论了八个头颈部标本。AR引导的术中咨询用于标本定位和FSA边缘采样部位的讨论。一名患者的FSA初始切缘为阳性,并再次切除至阴性最终切缘。AR引导的FSA是可能的,并允许病理学家从任何位置加入手术进行术中讨论。
    Due to the anatomic complexity of the head and neck and variable proximity between laboratory and operating room (OR), effective communication during frozen section analysis (FSA) between surgeons and pathologists is challenging. This proof-of-concept study investigates an augmented reality (AR) protocol that allows pathologists to virtually join the OR from the laboratory. Head and neck cancer specimens were scanned ex vivo using a 3-dimensional scanner and uploaded into an AR platform. Eight head and neck specimens were discussed by surgeons and pathologists in an AR environment. AR-guided intraoperative consultation was used for specimen orientation and discussion of FSA margin sampling sites. One patient had positive initial margins on FSA and was re-resected to negative final margins. AR-guided FSA is possible and allows pathologists to join the operating from any location for intraoperative discussion.
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  • 文章类型: Journal Article
    实体器官移植受者(SOTR)的数量随着移植数量的增加和生存期的延长而增加;这些患者,因此,经常遭受各种合并症,并受到免疫抑制剂的有害影响,这使得他们患恶性肿瘤的风险更高。这些药物还使肿瘤的手术治疗复杂化,因为它们会阻碍伤口愈合,尤其是与其他不利因素相关时(例如,以前的放射治疗,糖尿病,等。).我们在此介绍了我们对74岁的SOTR的经验,该SOTR接受了根治性扩大腮腺切除术,并在放疗后使用下岛状皮瓣进行了重建,以治疗持续性皮肤鳞状细胞癌;他复杂的临床过程的特点是伤口愈合缓慢。回顾了当前的文献,以简要概述SOTR中头颈部手术的主要困难。特别是,考虑到个体风险,免疫抑制方案可以逐渐减少,其他因素应仔细评估,可能在手术前,防止累积伤害。新的发展,包括术中通过吲哚菁绿荧光视频血管造影监测皮瓣血管化,以及预防性应用负压伤口治疗,在可行的情况下,可能对高危患者特别有益。
    The number of solid organ transplant recipients (SOTRs) is growing as a consequence of an increase in transplantations and longer survival; these patients, thus, frequently suffer various comorbidities and are subjected to the detrimental effects of immunosuppressive agents, which expose them to a higher risk of developing malignancies. These drugs also complicate the surgical treatment of neoplasms, as they can hinder wound healing, especially when associated with other unfavorable factors (e.g., previous radiotherapy, diabetes, etc.). We herein present our experience with a 74-year-old SOTR who underwent a radical extended parotidectomy and reconstruction with a submental island flap for a persistent cutaneous squamous carcinoma after radiotherapy; his complicated clinical course was characterized by incredibly slow wound healing. The current literature was reviewed to provide a succinct overview of the main difficulties of head and neck surgery in SOTRs. In particular, the immunosuppressive regimen can be tapered considering the individual risk and other elements should be carefully assessed, possibly prior to surgery, to prevent cumulative harm. New developments, including intraoperative monitoring of flap vascularization through indocyanine green fluorescence video-angiography and the prophylactic application of negative pressure wound therapy, when feasible, may be particularly beneficial for high-risk patients.
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  • 文章类型: Case Reports
    激光热消融(LTA)是一种越来越常见的治疗良性和恶性甲状腺结节的方法,允许患者避免甲状腺切除术。在良性甲状腺结节患者中,很少有LTA术后并发症的报道。虽然声带麻痹是甲状腺切除术后众所周知的潜在并发症,我们介绍了首例LTA后声带麻痹的病例报告。一位80多岁的女性出现了甲状腺功能亢进和良性甲状腺结节的症状,出现了外部内分泌学家。病人接受了细针穿刺活检,放射性碘摄取扫描,放射性甲状腺消融术,和外部机构的LTA。患者在LTA后2天首先注意到声音嘶哑,她带着一个弱者来到我们办公室,手术后4个月以上的呼吸声音。视频镜检查显示左声带不活动,声门闭合不完整。在办公室清醒注射喉成形术后,患者经历了声音改善。总之,LTA是一种相对较新的治疗方式,关于不良结局的文献有限。随着LTA等微创技术变得越来越普遍,必须充分意识到识别和减轻声带麻痹等并发症的风险。
    Laser thermal ablation (LTA) is an increasingly common procedure to treat benign and malignant thyroid nodules, allowing patients to avoid thyroidectomy. There are few reported postprocedural complications of LTA among patients with benign thyroid nodules. While vocal fold paralysis is a well-known potential complication after thyroidectomy, we present the first case report of vocal fold paralysis following LTA. A female in her 80s presented to an outside endocrinologist with symptoms of hyperthyroidism and benign thyroid nodules. The patient underwent a fine needle aspiration biopsy, radioiodine uptake scan, radioactive thyroid ablation, and LTA at an outside institution. The patient first noticed hoarseness 2days after LTA, and she presented to our office with a weak, breathy voice more than 4months postprocedure. Videostroboscopic examination revealed immobility of the left vocal fold with incomplete glottic closure. After awake injection laryngoplasty in the office, the patient experienced voice improvement. In conclusion, LTA is a relatively new treatment modality with limited literature on adverse outcomes. As minimally invasive techniques such as LTA are becoming more common, it is essential to remain fully aware of risks to recognize and mitigate complications like vocal fold paralysis.
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  • 文章类型: Journal Article
    目的:手术显微镜在中耳和内耳程序中起着核心作用,这些程序涉及在有限的暴露下在密闭空间内工作。增强现实(AR)可以通过结合可以提供精确解剖信息的术前计算机断层扫描(CT)成像来改善手术指导,与术中显微镜视频馈送。以目前的技术,操作员必须使用计算机手动地与AR接口交互。后者造成手术流的破坏,并且对于维持手术环境的无菌性是次优的。这项研究的目的是利用手跟踪和手势识别来实施和评估徒手交互概念,以减少手术过程中的干扰并改善人机交互。
    方法:使用定制的3D打印校准板校准了电磁跟踪的手术显微镜。这允许通过分割的术前CT衍生的虚拟模型来增强显微镜馈送。Ultraleap的Leap运动控制器2与显微镜耦合,用于实现手动跟踪功能。在开发期间从外科医生收集最终用户反馈。最后,用户被要求完成涉及与虚拟模型交互的任务,将它们对准物理目标,并调整AR可视化。
    结果:根据观察和用户反馈,我们升级了手交互系统的功能。用户反馈显示了用户对新交互概念的偏好,这些新交互概念提供了对手术工作流程的最小干扰和与虚拟内容的更直观的交互。
    结论:我们整合了手交互概念,通常与头戴式显示器(HMD)一起使用,进入用于耳科显微外科AR的外科立体显微镜系统。这项研究中提出的概念证明了在手术环境中进行人机交互的更有利方法。它们具有在微观AR指导下更有效地执行手术任务的潜力。
    OBJECTIVE: The operating microscope plays a central role in middle and inner ear procedures that involve working within tightly confined spaces under limited exposure. Augmented reality (AR) may improve surgical guidance by combining preoperative computed tomography (CT) imaging that can provide precise anatomical information, with intraoperative microscope video feed. With current technology, the operator must manually interact with the AR interface using a computer. The latter poses a disruption in the surgical flow and is suboptimal for maintaining the sterility of the operating environment. The purpose of this study was to implement and evaluate free-hand interaction concepts leveraging hand tracking and gesture recognition as an attempt to reduce the disruption during surgery and improve human-computer interaction.
    METHODS: An electromagnetically tracked surgical microscope was calibrated using a custom 3D printed calibration board. This allowed the augmentation of the microscope feed with segmented preoperative CT-derived virtual models. Ultraleap\'s Leap Motion Controller 2 was coupled to the microscope and used to implement hand-tracking capabilities. End-user feedback was gathered from a surgeon during development. Finally, users were asked to complete tasks that involved interacting with the virtual models, aligning them to physical targets, and adjusting the AR visualization.
    RESULTS: Following observations and user feedback, we upgraded the functionalities of the hand interaction system. User feedback showed the users\' preference for the new interaction concepts that provided minimal disruption of the surgical workflow and more intuitive interaction with the virtual content.
    CONCLUSIONS: We integrated hand interaction concepts, typically used with head-mounted displays (HMDs), into a surgical stereo microscope system intended for AR in otologic microsurgery. The concepts presented in this study demonstrated a more favorable approach to human-computer interaction in a surgical context. They hold potential for a more efficient execution of surgical tasks under microscopic AR guidance.
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  • 文章类型: Journal Article
    目的:评估接受头颈部重建手术患者种族差异的国家趋势。
    方法:使用2008年至2021年美国外科医生学会国家外科质量改进计划数据库进行回顾性分析。接受微血管游离组织转移的患者符合纳入条件。排除儿科患者和非耳鼻喉科医师治疗的患者。用单变量和多变量模型分析结果。
    结果:共分析5831例头颈部游离皮瓣,4869(83.5%)为白人,560人(9.6%)是黑人或非裔美国人,402人(6.9%)为亚洲人,美洲原住民,或其他团体(ANAOG)。在该时间段内,黑人或非裔美国人患者和接受游离组织转移的ANAOG患者的比例显着增加(分别为p=0.047和p=0.010)。然而,2017年左右开始出现下降趋势。在多变量模型中,黑人或非裔美国人种族与再入院无关(OR=0.99[95%CI0.74,1.31],P>0.05),返回手术室(OR=1.20[95%CI0.96,1.49],P>0.05),或任何术后并发症(OR=0.83[95%CI0.68,1.01],p>0.05)。在多变量分析中,ANAOG人群中也没有发现显著的相关性(均p>0.05)。
    结论:在美国,少数背景的头颈癌患者中进行游离组织转移的百分比一直在增加。按种族分层时,头颈部微血管重建后的结果相似。然而,种族差异仍然存在,有必要进一步努力减少这些差异。
    方法:四级喉镜,2024.
    OBJECTIVE: To evaluate national trends in racial disparities for patients undergoing head and neck reconstructive surgery.
    METHODS: Retrospective analysis using the 2008 to 2021 American College of Surgeons National Surgical Quality Improvement Program database. Patients receiving microvascular free tissue transfer were eligible for inclusion. Pediatric patients and those treated by non-otolaryngologists were excluded. Outcomes were analyzed with univariate and multivariable models.
    RESULTS: A total of 5831 head and neck free flap cases were analyzed, 4869 (83.5%) were White, 560 (9.6%) were Black or African American, and 402 (6.9%) were Asian, Native American, or other groups (ANAOG). The proportion of Black or African American patients and ANAOG patients undergoing free tissue transfer increased significantly over the time period (p = 0.047 and p = 0.010, respectively). However, there was a downtrend that started around 2017. In a multivariable model, Black or African American race was not associated with readmission (OR = 0.99 [95% CI 0.74, 1.31], p > 0.05), returning to the operating room (OR = 1.20 [95% CI 0.96, 1.49], p > 0.05), or any post-operative complication (OR = 0.83 [95% CI 0.68, 1.01], p > 0.05). There were also no significant associations found in the ANAOG population on multivariate analysis (p > 0.05 for all).
    CONCLUSIONS: The percentage of free tissue transfer performed in patients from minority backgrounds with head and neck cancer has been increasing in the United States. Outcomes after head and neck microvascular reconstruction are similar when stratified by race. However, racial disparities remain and further work is necessary to reduce these disparities.
    METHODS: Level IV Laryngoscope, 2024.
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  • 文章类型: Case Reports
    舌骨相关颈动脉损伤是神经血管事件的罕见原因。这份报告描述了一个年轻人的案例,健康男性出现颈部疼痛,然后出现左侧偏瘫。该患者被诊断为短暂性脑缺血发作,这归因于右颈内动脉血管表面的结构损伤,这是细长舌骨持续压迫的直接结果。我们在六血管脑血管造影中使用一系列动作描述了成功的诊断。基因检测后来证实了血管Ehlers-Danlos综合征的诊断。
    Hyoid bone-related carotid injury is a rare cause of neurovascular events. This report describes a case of a young, healthy male presenting with neck pain followed by left-sided hemiparesis. The patient was diagnosed with a transient ischaemic attack attributed to structural damage of the vascular surface of the right internal carotid artery as a direct result of continuous compression by an elongated hyoid bone. We describe a successful diagnosis using a series of manoeuvres during a six-vessel cerebral angiogram. Genetic testing later confirmed the diagnosis of vascular Ehlers-Danlos syndrome.
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  • 文章类型: Journal Article
    目的:比较游离皮瓣重建时接受和未接受血管加压药(VP)的患者的游离皮瓣结局。
    方法:这项回顾性队列研究包括2013年1月至2023年1月的患者。
    方法:这项多中心队列研究利用了TriNetX研究网络的数据,该网络包括80个医疗机构。
    方法:将18岁以上接受游离皮瓣重建的头颈部癌患者分为在手术当天接受或未接受VPs的患者。主要结果是皮瓣失败,定义为需要二次游离皮瓣手术,血管修复,和其他襟翼修正程序。
    结果:在倾向得分匹配后,对7446例患者进行分析。VP组包括3723例患者(平均年龄[SD],62.9[11.4]岁;2511名男性[67.4%])。非VP组包括3723例患者(平均年龄[SD],63.0[11.2]岁;2479名男性[66.6%])。游离皮瓣结果组间无统计学差异(次级游离皮瓣:166[4.5%]VPvs155[4.2%]非VP,P=.04;血管修复:314[8.4%]对319[8.6%],P=.06;其他皮瓣翻修程序:416[11.2%]vs449[12.1%],P=.02)。发现VP组的骨皮瓣的血管修复率降低(47[6.1%]vs69[9.0%],P=0.003]。对于次要结果,肺炎(173[4.6%]vs231[6.2%],P=.0002),尿路感染(34[1.0%]vs59[1.6%],P=.0007),深静脉血栓形成(93[2.5%]vs122[3.3%],P=.004)有显著差异。
    结论:VP使用与游离皮瓣并发症无显著相关性。这些结果表明,如果临床需要,在手术当天使用VP可能是安全的。
    OBJECTIVE: To compare free flap outcomes between those who received and did not receive vasopressors (VPs) at the time of free flap reconstruction.
    METHODS: This retrospective cohort study includes patients from January 2013 to January 2023.
    METHODS: This multicenter cohort study utilized data from the TriNetX Research Network which includes 80 health care organizations.
    METHODS: Head and neck cancer patients older than 18 years who underwent free flap reconstruction were separated into those who received or did not receive VPs on the day of surgery. The primary outcomes were flap failure defined by need for secondary free flap procedures, blood vessel repair, and other flap revision procedures.
    RESULTS: After propensity score matching, 7446 patients were analyzed. The VP group included 3723 patients (mean age [SD], 62.9 [11.4] years; 2511 males [67.4%]). The non-VP group included 3723 patients (mean age [SD], 63.0 [11.2] years; 2479 males [66.6%]). Free flap outcomes were not statistically different between groups (secondary free flap: 166 [4.5%] VP vs 155 [4.2%] non-VP, P = .04; vessel repair: 314 [8.4%] vs 319 [8.6%], P = .06; other flap revision procedures: 416 [11.2%] vs 449 [12.1%], P = .02). Bony flaps were found to have decreased rates of vessel repair in the VP group (47 [6.1%] vs 69 [9.0%], P = .003]. For secondary outcomes, pneumonia (173 [4.6%] vs 231 [6.2%], P = .0002), urinary tract infection (34 [1.0%] vs 59 [1.6%], P = .0007), and deep vein thrombosis (93 [2.5%] vs 122 [3.3%], P = .004) were significantly different.
    CONCLUSIONS: VP use is not significantly associated with free flap complications. These results imply that VP use on the same day as surgery may be safe if clinically necessary.
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  • 文章类型: Journal Article
    增强现实(AR)技术已在耳鼻咽喉头颈外科手术中广泛建立。在过去的20年里,已经在各个子专业中对许多AR系统进行了研究和验证,在尸体和活体手术研究中。AR显示器通过头戴式设备投影,显微镜,还有内窥镜,最常见的是,在术前计划中表现出了实用性,术中指导,改善手术决策。具体来说,他们已经证明了指导肿瘤边缘切除的可行性,术中识别关键结构,并显示来自术前成像的患者特定虚拟模型,毫米精度。这篇综述总结了既有的AR技术和新兴的AR技术,详细说明他们的系统是如何工作的,他们提供什么功能,以及它们在耳鼻喉科亚专科的临床影响。随着AR技术的不断进步,它的整合有望提高手术精度,模拟训练,最终,改善患者预后。
    Augmented reality (AR) technology has become widely established in otolaryngology-head and neck surgery. Over the past 20 years, numerous AR systems have been investigated and validated across the subspecialties, both in cadaveric and in live surgical studies. AR displays projected through head-mounted devices, microscopes, and endoscopes, most commonly, have demonstrated utility in preoperative planning, intraoperative guidance, and improvement of surgical decision-making. Specifically, they have demonstrated feasibility in guiding tumor margin resections, identifying critical structures intraoperatively, and displaying patient-specific virtual models derived from preoperative imaging, with millimetric accuracy. This review summarizes both established and emerging AR technologies, detailing how their systems work, what features they offer, and their clinical impact across otolaryngology subspecialties. As AR technology continues to advance, its integration holds promise for enhancing surgical precision, simulation training, and ultimately, improving patient outcomes.
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