化脓性汗腺炎(HS)是一种终末毛囊的自身炎症性皮肤病,可以零星存在,家族性,或综合征形式。已经对后者提出了分类,区分与已知遗传状况相关的病例,滤泡角质化疾病或自身炎性疾病。这篇综述侧重于这些实体的临床和遗传特征(即,坏疽性脓皮病[PG],痤疮和HS;PG,痤疮,化脓性关节炎和HS;银屑病关节炎,PG,痤疮和HS;滑膜炎,痤疮,脓疱病,骨增生,骨炎;等等),提出了与HS相关的自身炎症综合征的统称。
Hidradenitis suppurativa (HS) is an autoinflammatory skin disorder of the terminal hair follicle, which can present in sporadic, familial, or syndromic form. A classification has been proposed for the latter, distinguishing cases associated with a known genetic condition, with follicular keratinization disorders or with autoinflammatory diseases. This review focuses on the clinical and genetic features of those entities (ie, pyoderma gangrenosum [PG], acne and HS; PG, acne, pyogenic arthritis and HS; psoriatic arthritis, PG, acne and HS; synovitis, acne, pustulosis,
hyperostosis, osteitis; and so forth) for which the collective term HS-related autoinflammatory syndromes is proposed.