背景:虽然众所周知,第二语言(L2)学习成功会随着年龄和个体的变化而变化,导致这种发育转变的潜在神经机制和这些个体差异在很大程度上是未知的。我们将在一个大的横断面发展样本中研究为新语法和单词学习服务的行为和神经因素。这项研究属于NWO(荷兰组织WetenschappelijkOnderzoek[荷兰研究委员会])语言互动联盟(网站:https://www。语言交互。nl/)。
方法:我们将在8至25岁的广泛年龄范围内对360名健康个体进行抽样。在本文中,我们描述了研究设计和方案,其中涉及多个研究访问,涵盖全面的行为电池和广泛的磁共振成像(MRI)协议。在这些措施的基础上,我们将创建行为和神经指纹,以捕获新语言学习中基于年龄的和个体差异。行为指纹将基于第一和第二语言能力,内存系统,和执行功能。我们将使用以下MRI模式绘制每个参与者的神经指纹:T1加权,扩散加权,静息态功能磁共振成像,和多功能MRI范例。关于功能性MRI测量,样本的一半将学习语法特征,一半将学习新语言的单词。结合所有个体指纹使我们能够探索神经成熟对语法和单词学习的影响。
结论:这将是迄今为止最大的神经影像学研究之一,该研究调查了从青春期前到成年期的L2学习的发育转变。我们结合行为和神经影像学数据的综合方法将有助于理解影响这种发展转变和新语言学习中个体差异的机制。我们的目标是:(I)这些指纹是否根据年龄而有所不同,这些指纹是否可以解释在新语言学习中观察到的与年龄相关的差异?(II)行为和神经指纹的哪些方面解释了语法和单词学习中的个体差异(年龄之间和年龄之间)?这项研究的结果提供了一个独特的机会来了解大脑结构和功能的发展如何影响新语言学习的成功。
BACKGROUND: While it is well established that second language (L2) learning success changes with age and across individuals, the underlying neural mechanisms responsible for this developmental shift and these individual differences are largely unknown. We will study the behavioral and neural factors that subserve new grammar and word learning in a large cross-sectional developmental sample. This study falls under the NWO (Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Dutch Research Council]) Language in Interaction consortium (website: https://www.languageininteraction.nl/ ).
METHODS: We will sample 360 healthy individuals across a broad age range between 8 and 25 years. In this paper, we describe the study design and protocol, which involves multiple study visits covering a comprehensive behavioral battery and extensive magnetic resonance imaging (MRI) protocols. On the basis of these measures, we will create behavioral and neural fingerprints that capture age-based and individual variability in new language learning. The behavioral fingerprint will be based on first and second language proficiency, memory systems, and executive functioning. We will map the neural fingerprint for each participant using the following MRI modalities: T1-weighted, diffusion-weighted, resting-state functional MRI, and multiple functional-MRI paradigms. With respect to the functional MRI measures, half of the sample will learn grammatical features and half will learn words of a new language. Combining all individual fingerprints allows us to explore the neural maturation effects on grammar and word learning.
CONCLUSIONS: This will be one of the largest neuroimaging studies to date that investigates the developmental shift in L2 learning covering preadolescence to adulthood. Our comprehensive approach of combining behavioral and neuroimaging data will contribute to the understanding of the mechanisms influencing this developmental shift and individual differences in new language learning. We aim to answer: (I) do these fingerprints differ according to age and can these explain the age-related differences observed in new language learning? And (II) which aspects of the behavioral and neural fingerprints explain individual differences (across and within ages) in grammar and word learning? The results of this study provide a unique opportunity to understand how the development of brain structure and function influence new language learning success.