■微创青光眼手术(MIGS)通常不用于晚期青光眼患者。这项研究描述了晚期开角型青光眼(OAG)患者接受XEN植入白内障手术或房角镜辅助的经腔小梁切开术(GATT)白内障手术的结果和并发症。
■这项回顾性研究确定了接受XEN植入或GATT治疗晚期OAG的患者。结果包括手术成功,眼内压(IOP)降低,局部降眼压滴剂的数量,视野平均偏差(MD),最佳矫正视力(BCVA),和并发症。手术成功定义为IOP<14mmHg,并且在没有局部降低IOP的滴剂(完全成功)或局部降低IOP的滴剂(合格成功)的情况下在12个月时降低20%。
■这项研究纳入了70只眼睛,包括35名接受XEN植入的患者和35名接受GATT的患者。接受XEN植入的眼睛的总体手术成功率为74.3%(35个中的26个),接受GATT的眼睛的总体手术成功率为71.4%(35个中的25个)。在XEN队列中,从基线到术后12个月的眼压降低百分比为48%,在GATT队列中为32%。术后12个月,XEN(3.26±1.15-1.23±1.28)(p<0.001)和GATT(2.46±1.12-0.43±0.78)(p<0.001)组的局部降眼压滴剂使用显着减少。唯一报告的并发症是短暂的前房积血,发生在XEN组的三名患者和GATT组的四名患者中,自发解决。
■在治疗晚期OAG患者时,XEN植入和GATT都可能是安全有效的管理选择。然而,需要更大的样本量来对这些技术进行直接的统计比较。
■在这项研究中,在晚期OAG患者中,XEN植入和GATT联合白内障手术均具有良好的预后。
■RupareliaS,谢里夫M,Shoham-HazonN.XEN植入和房角镜检查辅助经腔小梁切开术治疗晚期开角型青光眼的疗效和安全性。JCurr青光眼Pract2023;17(2):63-67。
UNASSIGNED: Minimally invasive glaucoma surgery (MIGS) is not typically used in patients with advanced-stage glaucoma. This study describes the outcomes and complications of patients with advanced open-angle glaucoma (OAG) who underwent XEN implantation with cataract surgery or gonioscopy-assisted transluminal trabeculotomy (GATT) with cataract surgery.
UNASSIGNED: This retrospective study identified patients who had undergone XEN implantation or GATT for the management of advanced OAG. Outcomes included surgical success, intraocular pressure (IOP) reduction, number of topical IOP-lowering drops, visual field mean deviation (MD), best-corrected visual acuity (BCVA), and complications. Surgical success was defined as an IOP of <14 mm Hg and a 20% reduction at 12 months without topical IOP-lowering drops (complete success) or with topical IOP-lowering drops (qualified success).
UNASSIGNED: Exactly 70 eyes were enrolled in this study, including 35 who had undergone XEN implantation and 35 who had undergone GATT. The overall surgical success rate was 74.3% (26 of 35) for eyes that underwent XEN implantation and 71.4% (25 of 35) for eyes that underwent GATT. Percent IOP reduction from baseline to 12 months postoperatively was 48% in the XEN cohort and 32% in the GATT cohort. Significant reduction in the use of topical IOP-lowering drops was demonstrated for both XEN (3.26 ± 1.15-1.23 ± 1.28) (p < 0.001) and GATT (2.46 ± 1.12-0.43 ± 0.78) (p < 0.001) cohorts at 12 months postoperatively. The only complication reported was transient hyphema, which occurred in three patients from the XEN group and four from the GATT group, and resolved spontaneously.
UNASSIGNED: Both XEN implantation and GATT may be safe and effective management options when treating patients with advanced OAG. However, larger sample sizes are required to make direct statistical comparisons between these techniques.
UNASSIGNED: In this study, XEN implantation and GATT combined with cataract surgery were each associated with favorable outcomes in patients with advanced OAG.
UNASSIGNED: Ruparelia S, Sharif M, Shoham-Hazon N. Efficacy and Safety Outcomes of XEN Implantation and Gonioscopy-assisted Transluminal Trabeculotomy for the Management of Advanced Open-angle Glaucoma. J Curr Glaucoma Pract 2023;17(2):63-67.