目的:确定膀胱镜引导激光消融壁内异位输尿管(CLA-EU)术后尿失禁的预测因素。
方法:回顾性纳入41名客户所有的女性金毛犬,单或双侧壁内异位输尿管。
方法:患者经超声和膀胱镜检查诊断为输尿管异位。对所有狗进行CLA-EU,以便单个操作员认为每个输尿管开口处于适当位置。所有狗在手术后通过电话进行短期随访4周和长期随访>10周,其中包括尿失禁评分。评估临床因素以及最初表现的超声和膀胱镜检查结果,以确定术后尿失禁的预测因素。
结果:在没有额外药物治疗的情况下,有46.3%的狗实现了短期尿失禁。在CLA-EU之前存在历史尿路感染(OR,0.130;95%CI,0.020~0.621;P=0.018)与输尿管扩张(OR,34.260;95%CI,1.813至2,143;P=.043)与尿失禁的可能性呈正相关。63.4%的狗实现了长期尿失禁,和历史尿路感染的存在是负面预后(OR,0.173;95%CI,0.023至0.856;P=0.048)。
结论:接受CLA-EU的雌性金毛猎犬与其他混合品种队列的结果相似,其中>30%的狗未能恢复尿失禁。在我们的人群中,历史尿路感染与短期和长期尿失禁显着相关。
OBJECTIVE: To identify predictive factors for postoperative continence in female Golden Retrievers following cystoscopic-guided laser ablation of intramural ectopic ureters (CLA-EU).
METHODS: 41 client-owned female entire Golden Retrievers with uni- or bilateral intramural ectopic ureter(s) were retrospectively enrolled.
METHODS: Patients were diagnosed with ectopic ureters with a combination of ultrasonography and cystoscopy. CLA-EU was performed for all dogs so that each ureteral opening was considered to be in an appropriate position by a single operator. All dogs had short-term follow-up 4 weeks and long-term follow up > 10 weeks after the procedure via telephone, which included urinary continence scoring. Clinical factors and ultrasonographic and cystoscopic findings from initial presentation were evaluated to identify predictive factors for postoperative continence.
RESULTS: Short-term urinary continence was achieved in 46.3% of dogs with no additional medical therapies. Presence of historical urinary tract infections prior to CLA-EU (OR, 0.130; 95% CI, 0.020 to 0.621; P = .018) was negatively correlated and ureteral dilatation (OR, 34.260; 95% CI, 1.813 to 2,143; P = .043) was positively correlated with likelihood of urinary continence. Long-term urinary continence was achieved in 63.4% of dogs, and presence of historical urinary tract infections was negatively prognostic (OR, 0.173; 95% CI, 0.023 to 0.856; P = .048).
CONCLUSIONS: Female Golden Retrievers undergoing CLA-EU have similar outcomes to those reported for other mixed-breed cohorts with > 30% of dogs failing to regain urinary continence. Historical urinary tract infections were significantly associated with both short- and long-term urinary continence in our population.