Geospatial

地理空间
  • 文章类型: Journal Article
    背景:药物的巨大后果包括自杀,交通事故,暴力,影响个人,家庭,社会,和国家。因此,有必要不断确定和监测在校青年的药物滥用率。地理空间仪表板对于在决策支持系统中监测药物滥用和相关犯罪发生率至关重要。
    目的:本文主要致力于开发MyAsriGeo,为学校学生量身定制的地理空间药物滥用风险评估和监测仪表板。它引入了创新的功能,使用多元学生数据无缝协调药物滥用使用模式和风险评估。
    方法:在本研究中,基于敏捷方法和原型设计,设计和开发了用于监测和分析的地理空间药物滥用仪表板。使用焦点小组和访谈,我们首先检查并收集了要求,反馈,和用户对MyAsriGeo仪表板的批准。专家和利益相关者,如国家禁毒局,警察,联邦城乡规划部,学校讲师,学生,研究人员也是做出回应的人之一。共有20名专家参与了仪表板试点和最终版本的需求分析和验收评估。评估试图确定用户接受的各个方面,例如易用性和实用性,对于试点和最终版本,以及基于研究后系统可用性问卷和任务技术拟合模型的2个其他因素,用于评估最终版本的界面质量和仪表板充分性。
    结果:MyAsriGeo地理空间仪表板旨在满足所有用户类型的需求,通过需求收集过程确定。它包括几个关键功能,例如显示药物滥用高风险区域位置的地理空间地图,学生药物滥用数据,评估不同地区药物滥用风险的工具,人口统计信息,和自我问题测试。还包括酒精,吸烟,和物质参与筛查测试及其风险评估,以帮助用户理解和解释学生风险的结果。仪表板的初始原型和最终版本由20名专家进行了评估,这显示了易用性(P=0.047)和有用性(P=0.02)因素的显着改善,并显示了易用性的高接受平均得分(4.2),有用性(4.46),接口质量(4.29),充足(4.13)。
    结论:MyAsriGeo地理空间仪表板可用于监测和分析马来西亚在校青少年的药物滥用情况。它是根据各种利益攸关方的需求开发的,包括一系列职能。仪表板由一组专家进行了评估。总的来说,MyAsriGeo地理空间仪表板是帮助利益攸关方理解和应对青年药物滥用问题的宝贵资源。
    BACKGROUND: The enormous consequences of drugs include suicides, traffic accidents, and violence, affecting the individual, family, society, and country. Therefore, it is necessary to constantly identify and monitor the drug abuse rate among school-going youth. A geospatial dashboard is vital for the monitoring of drug abuse and related crime incidence in a decision support system.
    OBJECTIVE: This paper mainly focuses on developing MyAsriGeo, a geospatial drug abuse risk assessment and monitoring dashboard tailored for school students. It introduces innovative functionality, seamlessly orchestrating the assessment of drug abuse usage patterns and risks using multivariate student data.
    METHODS: A geospatial drug abuse dashboard for monitoring and analysis was designed and developed in this study based on agile methodology and prototyping. Using focus group and interviews, we first examined and gathered the requirements, feedback, and user approval of the MyAsriGeo dashboard. Experts and stakeholders such as the National Anti-Drugs Agency, police, the Federal Department of Town and Country Planning, school instructors, students, and researchers were among those who responded. A total of 20 specialists were involved in the requirement analysis and acceptance evaluation of the pilot and final version of the dashboard. The evaluation sought to identify various user acceptance aspects, such as ease of use and usefulness, for both the pilot and final versions, and 2 additional factors based on the Post-Study System Usability Questionnaire and Task-Technology Fit models were enlisted to assess the interface quality and dashboard sufficiency for the final version.
    RESULTS: The MyAsriGeo geospatial dashboard was designed to meet the needs of all user types, as identified through a requirement gathering process. It includes several key functions, such as a geospatial map that shows the locations of high-risk areas for drug abuse, data on drug abuse among students, tools for assessing the risk of drug abuse in different areas, demographic information, and a self-problem test. It also includes the Alcohol, Smoking, and Substance Involvement Screening Test and its risk assessment to help users understand and interpret the results of student risk. The initial prototype and final version of the dashboard were evaluated by 20 experts, which revealed a significant improvement in the ease of use (P=.047) and usefulness (P=.02) factors and showed a high acceptance mean scores for ease of use (4.2), usefulness (4.46), interface quality (4.29), and sufficiency (4.13).
    CONCLUSIONS: The MyAsriGeo geospatial dashboard is useful for monitoring and analyzing drug abuse among school-going youth in Malaysia. It was developed based on the needs of various stakeholders and includes a range of functions. The dashboard was evaluated by a group of experts. Overall, the MyAsriGeo geospatial dashboard is a valuable resource for helping stakeholders understand and respond to the issue of drug abuse among youth.
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  • 文章类型: Journal Article
    当前研究的主要目的是使用哈特福德的七个批次,计划用于社区重复使用的CT,以确定最佳采样密度,该密度可以检测铅污染的热点,同时限制采样过程的工作量。以原位X射线荧光测量的土壤Pb作为评价土壤健康的指标,对采样密度进行了调查,美国环保局在2024年1月提出了200毫克/千克的新门槛。即使这项研究是在城市环境中进行的,由于存在其他可识别的污染物来源,因此新的USEPA政策要求使用100mg/kg的Pb阈值,只讨论了200-mg/kg阈值,因为从分析中可以明显看出,在城市地块中遵守100mg/kg阈值的可能性很小(七个地点中有五个在重新使用之前需要完整的现场挖掘)。使用原位pXRF确定的铅测量的逆距离加权地理空间插值,3-m的网格采样分辨率,4-m,5-m,6-m,8-m,10-m,和12米进行了比较。最终,该案例研究发现,可用于土壤筛选以保持污染热点以正确告知土壤管理决策的最大网格分辨率是6米网格,或密度约为1/36-m2。
    The main objective of the current study was to use seven lots in Hartford, CT that are planned for community reuse to determine the optimal sampling density that allows for the detection of hotspots of lead pollution while limiting the labor of the sampling process. The sampling density was investigated using soil Pb measured by in situ X-ray Fluorescence as the indicator to evaluate soil health, with a new threshold of 200-mg/kg proposed by the USEPA in January of 2024. Even though this study takes place in an urban setting, where the new USEPA policy requires the use of a 100-mg/kg threshold for Pb due to the fact that there are other identifiable sources of the contaminant, only the 200-mg/kg threshold is discussed because it is evident from the analysis that compliance of a 100 mg/kg threshold in urban plots is highly unlikely (five out of seven sites would require complete site excavation prior to reuse). Using the inverse distance weighted geospatial interpolation of in situ pXRF determined lead measurements, grid sampling resolutions of 3-m, 4-m, 5-m, 6-m, 8-m, 10-m, and 12-m were compared. Ultimately, the case study finds that the largest grid resolution that can be implemented for soil screening to maintain hotspots of pollution to properly inform soil management decisions is a 6-m grid, or a density of approximately 1/36-m2.
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  • 文章类型: Journal Article
    机器学习方法在地理空间环境问题上的应用越来越多,比如降水临近预报,雾霾预报,和作物产量预测。然而,许多应用于蚊子种群和疾病预测的机器学习方法本身并没有考虑到给定数据的潜在空间结构。在我们的工作中,我们应用由GraphSAGE层组成的空间感知图神经网络模型来预测伊利诺伊州西尼罗河病毒的存在,协助本州内的蚊子监测和消灭工作。更一般地说,我们表明,图神经网络应用于不规则采样的地理空间数据可以超过一系列基线方法的性能,包括逻辑回归,XGBoost,和完全连接的神经网络。
    Machine learning methods have seen increased application to geospatial environmental problems, such as precipitation nowcasting, haze forecasting, and crop yield prediction. However, many of the machine learning methods applied to mosquito population and disease forecasting do not inherently take into account the underlying spatial structure of the given data. In our work, we apply a spatially aware graph neural network model consisting of GraphSAGE layers to forecast the presence of West Nile virus in Illinois, to aid mosquito surveillance and abatement efforts within the state. More generally, we show that graph neural networks applied to irregularly sampled geospatial data can exceed the performance of a range of baseline methods including logistic regression, XGBoost, and fully-connected neural networks.
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  • 文章类型: Journal Article
    背景:先前的工作表明,社会环境因素会影响枪支伤害。密尔沃基县,威斯康星州是一个多元化的中西部县,对边缘化社区进行了历史性的撤资,导致种族和族裔界限严重隔离。它也是美国许多遭受枪支伤害的县之一。密尔沃基县社区之间的差异为探索可能影响枪支伤害临床结果和地理空间格局的社会环境因素的交集提供了独特的机会。
    方法:从地区成人一级创伤中心的创伤登记处查询了2015年至2022年遭受枪支相关伤害的患者(N=2402)。社会脆弱性指数(SVI)排名是使用患者居住地址得出的,以评估其与创伤性损伤临床结果的关联(即,住院死亡率,住院时间,ICU或呼吸机治疗,或损伤严重程度评分)和酒精使用障碍(AUD)的风险筛查结果,创伤后应激障碍(PTSD),和抑郁症。我们评估了随时间变化的枪支伤害密度的热点,用于患者的住所和伤害位置以及位置之间的距离。空间滞后回归模型测试了枪支伤害密度与SVI域之间的关联,酒精出口类型,公园覆盖。
    结果:大多数枪伤患者年龄较小,男性,来自弱势社区的种族或少数民族(SVI总计;M=0.86,SD=0.15)。SVI与任何临床结果无关。在那些被筛查的人中,12.9%的AUD筛查阳性,44.5%的PTSD风险筛查阳性,抑郁症,或者两者兼而有之。热点分析表明枪支伤害密度的浓度一致。在家庭内外受伤的人之间的临床结果没有差异。社会经济地位较低的人口普查区,更高的场外酒精出口密度和更低的本地酒精出口密度与更高的枪支伤害密度相关。
    结论:在密尔沃基县,火器伤害患者在可能阻碍康复的同一弱势社区受伤,并经常返回。结果复制并扩展了以前的工作,并暗示了干预和预防枪支伤害的特定社会环境因素。
    BACKGROUND: Previous work has shown socioenvironmental factors can influence firearm injury. Milwaukee County, Wisconsin is a diverse midwestern county with historic disinvestment in marginalized communities yielding stark segregation along racial and ethnic lines. It is also one of the many U.S. counties burdened by surging firearm injuries. The differences among communities within Milwaukee County provides a unique opportunity to explore the intersection of socioenvironmental factors that may affect clinical outcomes and geospatial patterns of firearm injury.
    METHODS: The trauma registry from the regional adult level 1 trauma center was queried for patients who sustained a firearm-related injury from 2015 to 2022 (N = 2402). The Social Vulnerability Index (SVI) ranking was derived using patient residence addresses to evaluate its association with traumatic injury clinical outcomes (i.e., in-hospital mortality, length of hospital stay, ICU or ventilator treatment, or injury severity score) and risk screening results for alcohol use disorder (AUD), posttraumatic stress disorder (PTSD), and depression. We evaluated hotspots of firearm injury density over time for patient residences and injury locations and distances between locations. A spatially lagged regression model tested the association between firearm injury density and SVI domains, alcohol outlet types, and park coverage.
    RESULTS: Most firearm injury patients were younger, male, racial or ethnic minorities from disadvantaged neighborhoods (SVI total; M = 0.86, SD = 0.15). SVI was not associated with any clinical outcomes. Of those screened, 12.9% screened positive for AUD and 44.5% screened at risk for PTSD, depression, or both. Hotspot analysis indicated consistent concentrations of firearm injury density. There were no differences in clinical outcomes between those injured inside or outside the home. Census tracts with lower socioeconomic status, greater off-premises and lower on-premises alcohol outlet density were associated with greater firearm injury density.
    CONCLUSIONS: In Milwaukee County, firearm injury patients are injured in and often return to the same disadvantaged neighborhoods that may hamper recovery. Results replicate and expand previous work and implicate specific socioenvironmental factors for intervention and prevention of firearm injury.
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  • 文章类型: Journal Article
    世界卫生组织确定了一个强大的疟疾及其蚊媒监测系统,作为消除疟疾议程的重要支柱。唾液按蚊抗体是暴露于蚊虫叮咬的新兴生物标志物,有可能克服传统昆虫学调查的敏感性和后勤限制。在例行监测期间,使用缅甸东南部104个村庄的乡村卫生志愿者网络收集的样本,本研究采用贝叶斯地统计建模框架,将气候和环境变量与按蚊唾液抗原血清学相结合,生成按蚊叮咬暴露的空间连续预测图。我们的地图量化了按蚊唾液抗体血清阳性率(9%至99%)的精细尺度的空间和时间异质性,这些异质性是按蚊叮咬暴露的代表,并提高了当前仅按蚊发生的静态地图。我们还开发了一个创新框架来监测疟疾传播。通过在联合贝叶斯地统计模型中掺入针对媒介和疟疾传播形式(子孢子)的抗体,我们预测了几个持续传播的焦点。在我们的研究中,我们证明了唾液按蚊和子孢子抗原的特异性抗体在逻辑上是可行的指标,可用于量化和表征接触媒介叮咬和疟疾传播的异质性.这些方法可以很容易地扩大到现有的乡村卫生志愿者监测网络中,以确定残留疟疾传播的重点,这可以有针对性的补充干预措施,以加快消除进展。
    The World Health Organization identifies a strong surveillance system for malaria and its mosquito vector as an essential pillar of the malaria elimination agenda. Anopheles salivary antibodies are emerging biomarkers of exposure to mosquito bites that potentially overcome sensitivity and logistical constraints of traditional entomological surveys. Using samples collected by a village health volunteer network in 104 villages in Southeast Myanmar during routine surveillance, the present study employs a Bayesian geostatistical modeling framework, incorporating climatic and environmental variables together with Anopheles salivary antigen serology, to generate spatially continuous predictive maps of Anopheles biting exposure. Our maps quantify fine-scale spatial and temporal heterogeneity in Anopheles salivary antibody seroprevalence (ranging from 9 to 99%) that serves as a proxy of exposure to Anopheles bites and advances current static maps of only Anopheles occurrence. We also developed an innovative framework to perform surveillance of malaria transmission. By incorporating antibodies against the vector and the transmissible form of malaria (sporozoite) in a joint Bayesian geostatistical model, we predict several foci of ongoing transmission. In our study, we demonstrate that antibodies specific for Anopheles salivary and sporozoite antigens are a logistically feasible metric with which to quantify and characterize heterogeneity in exposure to vector bites and malaria transmission. These approaches could readily be scaled up into existing village health volunteer surveillance networks to identify foci of residual malaria transmission, which could be targeted with supplementary interventions to accelerate progress toward elimination.
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  • 文章类型: Journal Article
    背景:健康的位置和环境社会决定因素在个人健康和社区层面公共卫生问题的监测中都是越来越重要的因素。
    目的:我们旨在测量位置混淆技术的程度,旨在保护个人的隐私,会无意间将地理坐标转移到社会经济人口统计学差异显著的社区,这限制了公共卫生利益相关者的调查结果的准确性。
    方法:点模糊技术故意模糊地理坐标以隐藏原始位置。风车混淆方法是一种现有技术,其中在给定随机选择的角度和最大半径的情况下,点沿着风车状路径移动;我们通过比较来自美国人口普查局的数据,通过比较原始点和最终移位点的人口统计来使用2个数据集评估该技术的影响。
    结果:使用贫困措施表明,低贫困地区的点可能会转移到高贫困地区;同样,高贫困地区的点可能会转移到低贫困地区。我们改变了最大允许混淆半径;混淆前后贫困率的平均差异为6.5%至11.7%。此外,混淆无意中造成了库克县自杀死亡的虚假热点,伊利诺伊州。
    结论:隐私问题要求患者位置不精确,以防止识别风险;精确的公共卫生要求准确性。我们提出了一种改进的混淆技术,该技术仅限于在指定的人口普查指定区域内生成一个新点,以通过避免人口统计学变化来保护隐私和分析准确性。
    BACKGROUND: Location and environmental social determinants of health are increasingly important factors in both an individual\'s health and the monitoring of community-level public health issues.
    OBJECTIVE: We aimed to measure the extent to which location obfuscation techniques, designed to protect an individual\'s privacy, can unintentionally shift geographical coordinates into neighborhoods with significantly different socioeconomic demographics, which limits the precision of findings for public health stakeholders.
    METHODS: Point obfuscation techniques intentionally blur geographic coordinates to conceal the original location. The pinwheel obfuscation method is an existing technique in which a point is moved along a pinwheel-like path given a randomly chosen angle and a maximum radius; we evaluate the impact of this technique using 2 data sets by comparing the demographics of the original point and the resulting shifted point by cross-referencing data from the United States Census Bureau.
    RESULTS: Using poverty measures showed that points from regions of low poverty may be shifted to regions of high poverty; similarly, points in regions with high poverty may be shifted into regions of low poverty. We varied the maximum allowable obfuscation radius; the mean difference in poverty rate before and after obfuscation ranged from 6.5% to 11.7%. Additionally, obfuscation inadvertently caused false hot spots for deaths by suicide in Cook County, Illinois.
    CONCLUSIONS: Privacy concerns require patient locations to be imprecise to protect against risk of identification; precision public health requires accuracy. We propose a modified obfuscation technique that is constrained to generate a new point within a specified census-designated region to preserve both privacy and analytical accuracy by avoiding demographic shifts.
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  • 文章类型: Journal Article
    识别人为影响的影响需要实施生物指标,以量化自然陆地和水生生态系统对扰动和转化的敏感性和脆弱性。尽管巴西的法律法规承认生物指标在监测水质方面的价值,土壤条件的贬值尚未得到足够的重视。因此,我们的研究旨在评估牙齿动物(蜻蜓和豆娘)作为两栖生物指标的潜力,以反映牧场为主的景观中水生和陆地栖息地退化之间的相关性。我们评估了Odonata的生物指数与巴西大草原40条溪流中与人为改变的牧场相邻的保留河岸景观的保护状况之间的关系。我们的结果支持以下假设:Odonata物种组成可能是土壤和水完整性的替代指标,使它们成为有前途的哨兵,以检测环境退化并指导人类改变的景观中的保护策略。重要的是,虽然Zygoptera/Anisoptera物种比率是巴西森林中有用的生物指示工具,在这里开放的大草原上效果较差,因此需要一个替代索引。重要的是,虽然Zygoptera/Anisoptera物种比率是巴西森林中有用的生物指示工具,在这里开放的大草原上效果较差,因此需要一个替代索引。另一方面,我们的结果表明,蜻蜓生物指数是评估巴西大草原淡水栖息地的合适工具。我们还在环境完整性谱的两端确定了某些生物指示物种。
    Discerning the impact of anthropogenic impacts requires the implementation of bioindicators that quantify the susceptibilities and vulnerabilities of natural terrestrial and aquatic ecosystems to perturbation and transformation. Although legal regulations in Brazil recognize the value of bioindicators in monitoring water quality, the depreciation of soil conditions has yet to receive adequate attention. Thus, our study aimed to evaluate the potential of odonates (dragonflies and damselflies) as amphibiotic bioindicators to reflect the correlation between the degradation of aquatic and terrestrial habitats in pasture-dominated landscapes. We assessed the relationship between the biotic indices of Odonata and the conservation status of preserved riparian landscapes adjacent to anthropogenically altered pastures in 40 streams in the Brazilian savannah. Our results support the hypothesis that Odonata species composition may be a surrogate indicator for soil and water integrity, making them promising sentinels for detecting environmental degradation and guiding conservation strategies in human-altered landscapes. Importantly, while the Zygoptera/Anisoptera species ratio is a useful bioindicator tool in Brazilian forest, it is less effective in the open savannah here, and so an alternative index is required. Importantly, while the Zygoptera/Anisoptera species ratio is a useful bioindicator tool in Brazilian forest, it is less effective in the open savannah here, and so an alternative index is required. On the other hand, our results showed the Dragonfly Biotic Index to be a suitable tool for assessing freshwater habitats in Brazilian savannah. We also identified certain bioindicator species at both ends of the environment intactness spectrum.
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  • 文章类型: Journal Article
    背景:结构性种族主义产生心理健康差异。虽然有研究研究了贫困和教育等个人因素的影响,这些元素的集体贡献,作为结构性种族主义的表现,很少探索。密尔沃基县,威斯康星州,种族和社会经济的多样性,为这种多因素调查提供了独特的背景。
    目的:这项研究旨在描述密尔沃基县结构性种族主义与心理健康差异之间的关联,使用地理空间和深度学习技术的组合。我们使用了二级数据集,在联邦机构发布之前,所有数据都被汇总和匿名化。
    方法:我们跨域编译了217个地理参考解释变量,最初故意排除基于种族的因素,专注于非种族决定因素。这种方法旨在揭示导致心理健康不良的风险因素的潜在模式,随后重新整合种族,以定量评估种族主义的影响。变量选择结合了基于树的方法(随机森林)和常规技术,由方差通货膨胀因子和皮尔逊相关分析支持,以缓解多重共线性。使用地理加权随机森林模型来研究空间异质性和依赖性。自组织地图,结合K均值聚类,用于分析密尔沃基社区的数据,重点是量化结构性种族主义对精神健康不良患病率的影响。
    结果:虽然12个影响因素共同占社区心理健康变异性的95.11%,前六个因素——吸烟,贫穷,睡眠不足,缺乏健康保险,employment,和年龄-特别有影响力。主要是,非裔美国人社区受到不成比例的影响,这是2.23倍更有可能遇到高风险集群的心理健康差。
    结论:研究结果表明,结构性种族主义形成了心理健康差异,黑人社区成员受到不成比例的影响。多方面的方法论方法强调了整合地理空间分析和深度学习以理解心理健康的复杂社会决定因素的价值。这些见解突出了有针对性的干预措施的必要性,解决个人和系统因素,以减轻植根于结构性种族主义的心理健康差距。
    BACKGROUND: Structural racism produces mental health disparities. While studies have examined the impact of individual factors such as poverty and education, the collective contribution of these elements, as manifestations of structural racism, has been less explored. Milwaukee County, Wisconsin, with its racial and socioeconomic diversity, provides a unique context for this multifactorial investigation.
    OBJECTIVE: This research aimed to delineate the association between structural racism and mental health disparities in Milwaukee County, using a combination of geospatial and deep learning techniques. We used secondary data sets where all data were aggregated and anonymized before being released by federal agencies.
    METHODS: We compiled 217 georeferenced explanatory variables across domains, initially deliberately excluding race-based factors to focus on nonracial determinants. This approach was designed to reveal the underlying patterns of risk factors contributing to poor mental health, subsequently reintegrating race to assess the effects of racism quantitatively. The variable selection combined tree-based methods (random forest) and conventional techniques, supported by variance inflation factor and Pearson correlation analysis for multicollinearity mitigation. The geographically weighted random forest model was used to investigate spatial heterogeneity and dependence. Self-organizing maps, combined with K-means clustering, were used to analyze data from Milwaukee communities, focusing on quantifying the impact of structural racism on the prevalence of poor mental health.
    RESULTS: While 12 influential factors collectively accounted for 95.11% of the variability in mental health across communities, the top 6 factors-smoking, poverty, insufficient sleep, lack of health insurance, employment, and age-were particularly impactful. Predominantly, African American neighborhoods were disproportionately affected, which is 2.23 times more likely to encounter high-risk clusters for poor mental health.
    CONCLUSIONS: The findings demonstrate that structural racism shapes mental health disparities, with Black community members disproportionately impacted. The multifaceted methodological approach underscores the value of integrating geospatial analysis and deep learning to understand complex social determinants of mental health. These insights highlight the need for targeted interventions, addressing both individual and systemic factors to mitigate mental health disparities rooted in structural racism.
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  • 文章类型: Journal Article
    背景:淋巴丝虫病(LF)是一种使人衰弱的疾病,促进贫困,被忽视的热带病(NTD)的目标是到2030年在全球范围内消除作为公共卫生问题(EPHP)。评估国家方案在实现这一目标方面的进展具有挑战性,由于疾病传播和国家以下各级干预措施的差异。数学模型可以通过捕获空间异质性并评估消除LF的进展以及如何利用不同的干预措施来实现2030年的消除来帮助解决这些挑战。
    方法:在这里,我们使用了一种新颖的方法,将埃塞俄比亚LF的历史地理空间疾病流行图与3种当代疾病传播模型相结合,以预测国家以下各级不同干预方案下的感染趋势。
    结果:我们的研究结果表明,当地环境,特别是干预措施的覆盖面,是控制和消除计划成功的重要决定因素。此外,虽然目前的战略似乎足以在2030年实现消除LF,但一些地区可能会受益于替代战略的实施,例如使用增强的覆盖范围或增加的频率,加快实现2030年目标。
    结论:将LF的地理空间疾病流行图与传播模型和干预历史相结合,可以预测埃塞俄比亚不同控制情景下国家以下一级的感染趋势。这种方法,使传输模型适应本地设置,可能有助于为其他LF流行地区的国家以下一级的最佳干预措施的设计提供信息。
    BACKGROUND: Lymphatic filariasis (LF) is a debilitating, poverty-promoting, neglected tropical disease (NTD) targeted for worldwide elimination as a public health problem (EPHP) by 2030. Evaluating progress towards this target for national programmes is challenging, due to differences in disease transmission and interventions at the subnational level. Mathematical models can help address these challenges by capturing spatial heterogeneities and evaluating progress towards LF elimination and how different interventions could be leveraged to achieve elimination by 2030.
    METHODS: Here we used a novel approach to combine historical geo-spatial disease prevalence maps of LF in Ethiopia with 3 contemporary disease transmission models to project trends in infection under different intervention scenarios at subnational level.
    RESULTS: Our findings show that local context, particularly the coverage of interventions, is an important determinant for the success of control and elimination programmes. Furthermore, although current strategies seem sufficient to achieve LF elimination by 2030, some areas may benefit from the implementation of alternative strategies, such as using enhanced coverage or increased frequency, to accelerate progress towards the 2030 targets.
    CONCLUSIONS: The combination of geospatial disease prevalence maps of LF with transmission models and intervention histories enables the projection of trends in infection at the subnational level under different control scenarios in Ethiopia. This approach, which adapts transmission models to local settings, may be useful to inform the design of optimal interventions at the subnational level in other LF endemic regions.
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  • 文章类型: Journal Article
    背景:药房的可及性与整体健康和福祉有关。过去的研究表明,药店对低收入和少数民族社区的服务不足。然而,文献在发现地区级收入或种族和族裔组成与药房之间的联系方面不一致。在这里,我们的目标是评估纽约州(NYS)药房的区域级空间访问,假设贫困率较高,黑人和西班牙裔居民比例较高的人口普查区将具有较低的空间访问权限。
    方法:为纽约州的每个人口普查区计算了2018年到药房的人口加权平均最短道路网络距离(PWMSD)。此统计量是从一个区域内每个人口普查区块的质心到药房的最短道路网络距离计算得出的。人口普查区块的平均值由人口普查区块的人口加权。进行了横断面分析,以评估地区级社会人口统计学特征和地区级PWMSD与药房之间的联系。
    结果:总体而言,纽约市人口普查区药房的平均PWMSD为2.07Km(SD=3.35,中位数为0.85Km)。较短的PWMSD至药房与较高的Tract-level%贫困有关,%黑人/非洲裔美国人(AA)居民,以及西班牙裔/拉丁裔居民的百分比,以及具有大学学位的较低地区水平的居民的百分比。与%Black/AA居民中最低四分位数的区域相比,最高四分位数区域的药房PWMSD缩短70.7%(95%CI68.3-72.9%).同样,贫困率最高的四分位数中的片段与最低的四分位数中的片段相比,药房的PWMSD短61.3%(95%CI58.0-64.4%)。
    结论:分析表明,在具有较高种族和少数族裔人口和较高贫困率的NYS地区,药房的空间可达性更高。
    BACKGROUND: The accessibility of pharmacies has been associated with overall health and wellbeing. Past studies have suggested that low income and racial minority communities are underserved by pharmacies. However, the literature is inconsistent in finding links between area-level income or racial and ethnic composition and access to pharmacies. Here we aim to assess area-level spatial access to pharmacies across New York State (NYS), hypothesizing that Census Tracts with higher poverty rates and higher percentages of Black and Hispanic residents would have lower spatial access.
    METHODS: The population weighted mean shortest road network distance (PWMSD) to a pharmacy in 2018 was calculated for each Census Tract in NYS. This statistic was calculated from the shortest road network distance to a pharmacy from the centroid of each Census block within a tract, with the mean across census blocks weighted by the population of the census block. Cross-sectional analyses were conducted to assess links between Tract-level socio demographic characteristics and Tract-level PWMSD to a pharmacy.
    RESULTS: Overall the mean PWMSD to a pharmacy across Census tracts in NYS was 2.07 Km (SD = 3.35, median 0.85 Km). Shorter PWMSD to a pharmacy were associated with higher Tract-level % poverty, % Black/African American (AA) residents, and % Hispanic/Latino residents and with lower Tract-level % of residents with a college degree. Compared to tracts in the lowest quartile of % Black/AA residents, tracts in the highest quartile had a 70.7% (95% CI 68.3-72.9%) shorter PWMSD to a pharmacy. Similarly, tracts in the highest quartile of % poverty had a 61.3% (95% CI 58.0-64.4%) shorter PWMSD to a pharmacy than tracts in the lowest quartile.
    CONCLUSIONS: The analyses show that tracts in NYS with higher racial and ethnic minority populations and higher poverty rates have higher spatial access to pharmacies.
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