■暴露于空气污染与过早死亡的风险增加有关。然而,在发展中国家,空气污染对非意外死亡风险的急性影响尚未得到广泛研究,到目前为止,调查结果并不一致。因此,这项研究旨在研究北京短期暴露于六种污染物(PM2.5,PM10,SO2,NO2,O3和CO)与非意外死亡率之间的关系。中国。
■非意外死亡的每日数据收集时间为2017年1月1日至2018年12月31日。同期的空气污染数据来自北京35个固定站点的空气质量监测站。基于Poisson回归的广义累加模型(GAM)用于研究急诊科就诊的非意外死亡率与空气污染物每日平均水平之间的关系。
■在2017-2018年期间记录了8,676例非意外死亡。经过敏感性分析,短期接触空气污染物,特别是气态污染物,与非意外死亡率有关。具体来说,SO2每增加10μg/m3(SO2为5μg/m3,CO为0.5mg/m3)(滞后04),NO2(滞后04),O3(滞后05),和CO(滞后04),相对风险(RR)值为1.054(95%CI:1.009,1.100),1.038(95%CI:1.013,1.063),1.032(95%CI:1.011,1.054),和1.034(95%CI:1.004,1.066),分别。就死亡原因而言,短期暴露于NO2,SO2和O3会增加循环系统死亡的风险。进一步的分层分析显示,女性对O3表现出更强的关联,而男性对CO表现出更强的关联。65岁及以上的人群与环境空气污染密切相关。
■我们的研究表明,环境空气污染物与非意外死亡率有关。我们的研究结果表明,应该加大控制气态污染的力度,弱势群体应成为健康保护教育的重点。
Exposure to air pollution has been linked to an increased risk of premature mortality. However, the acute effects of air pollution on the risk of non-accidental mortality have not been extensively researched in developing countries, and the findings thus far have been inconsistent. Therefore, this study aimed to examine the association between short-term exposure to six pollutants (PM2.5, PM10, SO2, NO2, O3, and CO) and non-accidental mortality in Beijing, China.
Daily data on non-accidental deaths were gathered from 1 January 2017 to 31 December 2018. Air pollution data for the same period were collected from 35 fixed-site air quality monitoring stations in Beijing. Generalized additive models (GAM) based on Poisson regression were used to investigate the association between non-accidental mortality in emergency department visits and the daily average levels of air pollutants.
There were 8,676 non-accidental deaths recorded during 2017-2018. After sensitivity analysis, short-term exposure to air pollutants, particularly gaseous pollutants, was linked to non-accidental mortality. Specifically, for every 10 μg/m3 increase (5 μg/m3 in SO2, 0.5 mg/m3 in CO) of SO2 (lag 04), NO2 (lag 04), O3 (lag 05), and CO (lag 04), the relative risk (RR) values were 1.054 (95% CI: 1.009, 1.100), 1.038 (95% CI: 1.013, 1.063), 1.032 (95% CI: 1.011, 1.054), and 1.034 (95% CI: 1.004, 1.066), respectively. In terms of causes of death, short-term exposure to NO2, SO2, and O3 increased the risk of circulatory mortality. Further stratified analysis revealed that the stronger associations were presented in females for O3 while in males for CO. People aged 65 and over were strongly associated with ambient air pollution.
Our study showed that ambient air pollutants were associated with non-accidental mortality. Our findings suggested that efforts to control gaseous pollution should be stepped up, and vulnerable groups should be the focus of health protection education.