本报告详细介绍了一例罕见的胃鳞状细胞癌(SCC)病例,一种仅占胃癌一小部分的疾病。一名46岁的男性吞咽困难患者,腹痛,和呕血被诊断为原发性胃SCC显示侵袭性转移,一种发病率极低的疾病,主要影响男性的第六个十年。原发性胃SCC,虽然临床上与腺癌相似,涉及到更暗淡的预后,缺乏标准化的治疗方案。组织病理学和影像学证实了诊断,强调管理先进案例的挑战。姑息性化疗显示部分缓解,但导致严重的神经病变。该病例强调了迫切需要研究以了解其发病机理,有效管理,和原发性胃SCC的治疗目标,强调其在医学文献中的稀缺性和不良预后。提高临床意识和正在进行的研究对于改善这种罕见表现的结果至关重要。
This report details a rare case of squamous cell carcinoma (SCC) in the stomach, a condition accounting for only a fraction of gastric carcinomas. A 46-year-old male patient with dysphagia, abdominal pain, and haematemesis was diagnosed with primary gastric SCC displaying aggressive metastasis, an exceptionally low-incidence condition affecting mainly males in their sixth decade of life. Primary gastric SCC, though clinically similar to adenocarcinoma, involves a bleaker prognosis, lacking standardized treatment protocols. Histopathology and imaging confirmed the diagnosis, highlighting the challenges in managing advanced cases. Palliative chemotherapy showed partial remission but led to severe neuropathy. The case underscores the urgent need for research to understand the pathogenesis, effective management, and therapeutic targets for primary gastric SCC, emphasizing its scarcity and poor prognosis in medical literature. Increased clinical awareness and ongoing research are crucial for improving outcomes in such rare presentations.