Functional reconstruction

功能重建
  • 文章类型: Journal Article
    目的:探讨基于Roy适应模式(RAM)的协同护理对术后功能重建的影响。股骨粗隆间骨折患者的软组织疼痛和生活质量。
    方法:本研究采用回顾性配对对照方法。选择2018年7月至2021年9月我院收治的96例股骨粗隆间骨折患者。根据不同的护理方法,将患者分为协作组和常规组,每组48例。两组患者均采用髓内钉手术治疗。常规组给予常规围手术期护理干预,协作组在此基础上给予协同护理干预。比较两组干预前后髋关节功能恢复情况及生活质量。术前、术后疼痛程度,记录两组围手术期并发症。采用Logistic多因素回归分析影响股骨粗隆间骨折患者术后髋关节功能恢复的危险因素,从而构建风险预测模型。采用ROC曲线分析影响因素预测股骨粗隆间骨折患者术后髋关节功能恢复的临床价值。
    结果:合作组干预后Harris各维度评分明显高于干预前及常规组(P<0.05)。干预后,协作组髋关节功能优良率为83.33%,显著高于常规组的60.42%(P<0.05)。术后各时间点协同组VAS评分明显低于常规组(P<0.05)。干预后,生理功能的分数,生理作用,协作组的身体疼痛和一般健康状况明显高于常规组(P<0.05)。协作组并发症发生率为6.25%,显著低于常规组的22.92%(P<0.05)。年龄差异有统计学意义,术前ASA分级,内固定方法,髋关节恢复优组与髋关节恢复差组的骨质疏松分级及围手术期护理方法差异有统计学意义(P<0.05)。Logistic多因素回归分析显示,年龄,术前ASA分级,内固定方式和骨质疏松分级是影响术后髋关节功能恢复的危险因素,围手术期护理方法是保护因素(P<0.05)。影响因素中,内固定方式及骨质疏松程度对预测股骨粗隆间骨折患者术后髋关节功能恢复有一定的临床价值。
    结论:基于RAM模式的协同护理方法可有效恢复股骨粗隆间骨折患者术后髋关节功能。减轻患者围手术期疼痛程度,提高患者的生活质量,降低并发症的发生率,可在临床上推广应用。此外,影响股骨粗隆间骨折患者术后髋关节功能恢复的因素很多,根据影响因素采取有针对性的措施提高髓内钉治疗效果。
    OBJECTIVE: To explore the effect of collaborative nursing based on Roy Adaptive Mode (RAM) on postoperative functional reconstruction, soft tissue pain and quality of life in patients with femoral intertrochanteric fracture.
    METHODS: A retrospective matched control method was used in this study. A total of 96 patients with femoral intertrochanteric fracture admitted to our hospital from July 2018 to September 2021 were selected. According to different nursing methods, the patients were divided into a collaborative group and a routine group, with 48 cases in each group. Patients in both groups were treated with intramedullary nail surgery. The routine group was given routine perioperative nursing intervention, and the collaborative group was given collaborative nursing intervention on this basis. The hip function recovery and quality of life before and after the intervention were compared between the two groups. The preoperative and postoperative pain degree, and the perioperative complications of the two groups were recorded. Logistic multivariate regression analysis was used to analyze the risk factors affecting the recovery of hip joint function in patients with femoral intertrochanteric fracture after operation, thereby constructing a risk prediction model. ROC curve was used to analyze the clinical value of influencing factors in predicting postoperative hip function recovery in patients with femoral intertrochanteric fracture.
    RESULTS: Harris score each dimension after intervention in the collaborative group was obviously higher than that of before intervention and the conventional group (P < 0.05). After intervention, the excellent and good rate of hip joint function the collaborative group was 83.33%, which was significantly higher than 60.42% in the routine group (P < 0.05). Postoperative VAS scores each time point in the collaborative group was obviously lower than that in the routine group (P < 0.05). After intervention, the scores of physiological function, physiological role, body pain and general health in the collaborative group were significantly higher than those in the routine group (P < 0.05). The incidence of complications in the collaborative group was 6.25%, which was significantly lower than 22.92% in the routine group (P < 0.05). There were statistically significant differences in age, preoperative ASA grade, internal fixation method, osteoporosis grade and perioperative nursing methods between the excellent hip recovery group and the poor hip recovery group (P < 0.05). Logistic multivariate regression analysis showed that age, preoperative ASA grade, internal fixation method and osteoporosis grade were the risk factors affecting the recovery of hip joint function after operation, and perioperative nursing method was the protective factor (P < 0.05). Among the influencing factors, the internal fixation method and the grade of osteoporosis had certain clinical value in predicting the recovery of hip joint function in patients with femoral intertrochanteric fracture after operation.
    CONCLUSIONS: The RAM model-based collaborative nursing method may effectively restore the hip joint function of patients with femoral intertrochanteric fracture after operation, and may reduce the perioperative pain degree of patients, improve the quality of life of patients and reduce the incidence of complications, which can be popularized and applied in clinical practice. In addition, there are many factors influencing the recovery of hip joint function in patients with femoral intertrochanteric fracture after operation, and targeted measures should be taken according to the influencing factors to improve the effect of intramedullary nail treatment.
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  • 文章类型: Journal Article
    软骨粘液样纤维瘤(CMF)是一种罕见的软骨肿瘤,占良性骨肿瘤的<1%。我们报告一例颞下颌关节(TMJ)-CMF,涉及翼腭间隙和颅底,并讨论其流行病学,临床特征,和管理。
    一名56岁的妇女由于肿块向上扩展到耳颞部区域而表现出面部不对称和逐渐张口的限制。使用数字技术确定病变的边界并重建正常的关节盂窝,肿瘤切除后,在钛网和髁之间移植颞肌筋膜瓣以重建椎间盘。
    该病例突出了识别TMJ-CMF患者的重要性。
    UNASSIGNED: Chondromyxoid fibroma (CMF) is a rare cartilaginous tumor, accounting for < 1% of benign bone tumors. We report a case of temporomandibular joint (TMJ)-CMF, involving the pterygopalatine space and skull base and discuss its epidemiology, clinical characteristics, and management.
    UNASSIGNED: A 56-year-old woman presented with facial asymmetry and progressive mouth opening restriction due to a mass expanding upwardly to the auriculotemporal region. Using digital techniques to determine the lesion\'s boundary and reconstruct the normal glenoid fossa, the temporalis myofascial flap was transplanted between the titanium mesh and condyle to reconstruct the disc after tumor resection.
    UNASSIGNED: This case highlights the importance of identifying patients with TMJ-CMF.
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  • 文章类型: Journal Article
    背景:诊断为甲状腺乳头状癌(PTC)并侵犯气管的患者的外科治疗一直是讨论的主题,特别是关于气管功能重建的方法。这项研究的目的是检查气管侵犯的PTC患者的手术技术和预后。
    方法:本研究采用单变量和多变量Cox比例风险模型来确定影响气管侵犯PTC患者无进展生存期(PFS)的预测因素。采用R软件4.3.1版进行Cox回归分析。
    结果:在我们的研究中,我们纳入了247例T4aPTC患者。其中,146例患者(59.1%)被归类为ShinI,57例患者(23.1%)为ShinII-III,44例患者(17.8%)为申四。ShinI组的患者接受了气道肿瘤的剃须。ShinII中首选的手术方法,Ⅲ、Ⅳ组均为开窗切除(66.7%),套管切除(34.8%)和部分气管切除和皮肤瘘(61.8%),分别。多因素分析表明,气管手术和重建手术均未对T4aPTC伴气管侵犯患者的PFS产生影响。接受放射性碘(RAI)治疗的患者的5年DSS率为87.3%(p=0.033)。
    结论:本研究证实,气管手术和重建方法对不同Shin组气管侵犯的T4aPTC患者的PFS无影响。此外,RAI治疗有可能提高T4aPTC术前远处转移患者的生存率。
    BACKGROUND: The surgical management of patients diagnosed with papillary thyroid carcinoma (PTC) and tracheal invasion has been a subject of ongoing discussion, particularly regarding the approach to tracheal functional reconstruction. The objective of this study was to examine the surgical technique and prognosis of PTC patients with tracheal invasion.
    METHODS: This study employed both univariate and multivariate Cox proportional hazard models to determine predictive factors that affect the progression-free survival (PFS) of PTC patients with tracheal invasion. Cox regression analysis was conducted by using R software version 4.3.1.
    RESULTS: In our study, we included 247 patients with T4a PTC. Among them, 146 patients (59.1 %) were classified as Shin I, 57 patients (23.1 %) as Shin II-III, and 44 patients (17.8 %) as Shin IV. Patients in the Shin I group underwent shaving of the tumours in the airway. The preferred surgical methods in the Shin II, III and IV groups were window resection (66.7 %), sleeve resection (34.8 %) and partial tracheal resection and skin fistula (61.8 %), respectively. Multivariate analysis demonstrated that neither tracheal surgery nor reconstruction procedures had an impact on PFS in T4a PTC patients with tracheal invasion. The 5-year DSS rate for patients receiving radioiodine (RAI) therapy was 87.3 % (p = 0.033).
    CONCLUSIONS: This study confirmed that tracheal surgery and reconstruction methods had no impact on PFS in T4a PTC patients with tracheal invasion in different Shin groups. Furthermore, RAI therapy has the potential to increase the survival rate of patients with preoperative distant metastasis of T4a PTC.
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  • 文章类型: Journal Article
    目的:微血管骨瓣颌骨重建取得了满意的临床效果。然而,对重建颌骨的长期稳定性知之甚少。这项前瞻性纵向研究旨在研究颌骨重建的长期稳定性及其相关因素。
    方法:口腔颌面外科计算机辅助骨性游离皮瓣下颌骨重建成功的患者,玛丽医院,这项前瞻性纵向研究招募了香港。术前计划的三维颌骨模型,术后1个月,和2年进行了对齐和比较。
    结果:共招募了69名患者,其中48例患者可用于长期分析.与手术后1个月相比,术后2年观察到进一步偏离术前计划.手术缺乏准确性,节段性下颌骨切除,尤其是涉及下颌骨的角度,术后放射治疗被确定为影响重建颌骨位置稳定性的显著因素(p<0.05)。在未接受术后放射治疗的患者的亚组分析中观察到稳定的重建。
    结论:据我们所知,这是第一个前瞻性纵向研究报告颌骨重建的长期稳定性及其影响因素。我们的数据表明,重建的下颌位置在术后期间缺乏稳定性。如何提高重建颌骨的长期稳定性,从而优化功能结果,值得进一步研究。
    OBJECTIVE: Microvascular bone flap jaw reconstruction has achieved satisfactory clinical outcomes. However, little is known about the long-term stability of the reconstructed jaw. This prospective longitudinal study aimed to investigate the long-term stability of jaw reconstruction and factors that were associated with it.
    METHODS: Patients with successful computer-assisted osseous free-flap jaw reconstruction in the Department of Oral and Maxillofacial Surgery, Queen Mary Hospital, Hong Kong were recruited for this prospective longitudinal study. The three-dimensional jaw models at the pre-operative plan, post-operative 1-month, and 2 years were aligned and compared.
    RESULTS: A total of 69 patients were recruited, among which 48 patients were available for the long-term analysis. Compared to 1-month after surgery, further deviation from the pre-operative plan was observed at post-operative 2 years. Lack of accuracy in surgery, segmental mandible resection especially with the involvement of mandible angles, and post-operative radiation therapy were identified as the significant factors affecting the positional stability of the reconstructed jaw (p < 0.05). Stable reconstruction was observed in the subgroup analysis of patients without post-operative radiation therapy.
    CONCLUSIONS: Up to the best of our knowledge, this is the first prospective longitudinal study reporting the long-term stability of jaw reconstruction and its affecting factors. Our data demonstrated that the reconstructed jaw position lacked stability over the postoperative period. How to improve long-term stability of reconstructed jaw thus optimize the functional outcomes warrants further studies.
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  • 文章类型: Journal Article
    半月板损伤是膝关节内最常见的运动损伤之一,这也是骨关节炎(OA)的重要致病因素。由于无法从生物学和生物力学角度重建自然半月板的梯度异质性,目前的半月板替代产品远不能恢复半月板的生物功能。这里,受拓扑自诱导效应和原生弯月面微观结构的启发,我们通过基于机械/生物相容性高Mw聚(ε-己内酯)(PCL)的双级温度控制3D打印系统,提出了一种创新的组织工程半月板(TEM)具有独特的梯度尺寸金刚石孔微结构(GSDP-TEM)。生物学,独特的梯度微拓扑允许接种的间充质干细胞具有空间异质性分化,从里到外触发细胞外基质(ECM)的梯度过渡。生物力学,GSDP-TEM表现出与自然弯月面相似的优异的周向拉伸模量和载荷传递能力。植入兔膝关节后,GSDP-TEM诱导仿生异质新斑面的再生并有效减轻关节变性。本研究为功能性半月板重建提供了一种创新策略。拓扑自诱导的细胞分化和生物力学特性也为人体内其他复杂的异质结构重建提供了简单有效的解决方案,并具有很高的临床转化潜力。
    Meniscus injury is one of the most common sports injuries within the knee joint, which is also a crucial pathogenic factor for osteoarthritis (OA). The current meniscus substitution products are far from able to restore meniscal biofunctions due to the inability to reconstruct the gradient heterogeneity of natural meniscus from biological and biomechanical perspectives. Here, inspired by the topology self-induced effect and native meniscus microstructure, we present an innovative tissue-engineered meniscus (TEM) with a unique gradient-sized diamond-pored microstructure (GSDP-TEM) through dual-stage temperature control 3D-printing system based on the mechanical/biocompatibility compatible high Mw poly(ε-caprolactone) (PCL). Biologically, the unique gradient microtopology allows the seeded mesenchymal stem cells with spatially heterogeneous differentiation, triggering gradient transition of the extracellular matrix (ECM) from the inside out. Biomechanically, GSDP-TEM presents excellent circumferential tensile modulus and load transmission ability similar to the natural meniscus. After implantation in rabbit knee, GSDP-TEM induces the regeneration of biomimetic heterogeneous neomeniscus and efficiently alleviates joint degeneration. This study provides an innovative strategy for functional meniscus reconstruction. Topological self-induced cell differentiation and biomechanical property also provides a simple and effective solution for other complex heterogeneous structure reconstructions in the human body and possesses high clinical translational potential.
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  • 文章类型: Case Reports
    没有统一的方法可以同时恢复the上股四头肌腱和覆盖组织缺损。在这个案例报告中,我们提出带蒂股直肌肌皮瓣作为一种有效的方法,用于2例创伤相关的髌上股四头肌腱断裂和多次重建尝试后髌上肌腱结构广泛丢失或受损的病例。此外,我们对功能性带蒂股直肌肌皮瓣的重建应用进行了文献综述。
    方法:两名男性患者,48岁和74岁,由于多次重建尝试,髌上肌肉-肌腱结构广泛丢失或受损,用带蒂肌直肌皮瓣恢复膝关节伸展。
    结果:重建后三个月,两个病人都能自由行走,无帮助。经过六个月的随访,膝关节的自由被动活动恢复,并且两个患者都可以积极伸展膝关节。
    结论:作者得出结论,带蒂股直肌皮瓣是恢复膝关节伸展的可靠方法,在髌上肌腱病变的病例中具有出色的功能效果。在功能恢复方面,这种技术具有同时覆盖软组织缺损的额外优势,而直接关闭供体部位是可能的。老年患者和具有相关合并症或多次修订的患者可能特别受益于该技术。
    There is no unified approach for restoring the suprapatellar quadriceps tendon and covering tissue defects simultaneously. In this case report, we present the pedicled myocutaneous rectus femoris flap as one effective approach in two cases with extensive loss or impairment of the suprapatellar muscle-tendon structures after trauma-related suprapatellar quadriceps tendon rupture and multiple reconstruction attempts. Additionally, we provide a literature review of the reconstructive use of the functional pedicled myocutaneous rectus femoris flap.
    METHODS: Two male patients, 48 and 74 years old, with extensive loss or impairment of the suprapatellar muscle-tendon structures due to multiple reconstruction attempts, underwent restoration of the knee extension with a pedicled myocutaneous rectus femoris flap.
    RESULTS: Three months after reconstruction, both patients were able to walk freely, unaided. After a six-month follow-up, the free passive mobility of the knee joint was restored, and the active extension of the knee joint was possible in both patients.
    CONCLUSIONS: The authors conclude that the pedicled rectus femoris flap is a reliable method for the restoration of knee extension, with excellent functional results in cases of suprapatellar tendon lesions. Further to the functional restoration, this technique has the additional advantage of simultaneously achieving coverage of soft-tissue defects, while a direct closure of the donor site is possible. Elderly patients and patients with relevant comorbidities or multiple revisions may especially benefit from this technique.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:自由功能性肌肉转移是重建肿瘤切除术后下肢丢失肌肉单位的重建策略,创伤,筋膜室综合征,或者严重的神经损伤.在适当的情况下,自由的功能性肌肉转移可能是唯一合适的重建选择。本文回顾了自由功能肌肉转移的基本原理,其在下肢重建中的应用,适当的患者选择,和手术技术。
    方法:自由功能性肌肉转移的基本原理,其在下肢重建中的应用,适当的患者选择,并介绍了手术技术。讨论了适用于每种功能缺陷的常用供体肌肉。还对最近有关下肢游离功能性肌肉转移的出版物进行了审查。
    结果:良好的功能恢复,医学研究委员会等级高达4/5,并且可以通过自由的功能性肌肉转移来实现全方位的运动。介绍了下肢游离功能性肌肉转移的已发表病例系列的临床结果和具体参数,并提供了一个说明性病例。
    结论:对于适当的患者来说,自由功能性肌肉转移是一种合适的治疗方法,可以恢复基本功能并可能恢复下床活动。然而,我们还需要发表更多的临床结局,这也是进一步研究的主要领域.
    Free functional muscle transfer is a reconstructive strategy for the reconstruction of lost muscle units in the lower extremity after oncologic resection, trauma, compartment syndrome, or severe nerve injuries. Under appropriate circumstances, free functional muscle transfer may be the only suitable reconstructive option. This article reviews the underlying principles of free functional muscle transfer, its application to lower extremity reconstruction, appropriate patient selection, and surgical techniques.
    The underlying principles of free functional muscle transfer, its application to lower extremity reconstruction, appropriate patient selection, and surgical techniques are presented. Commonly used donor muscles appropriate for each type of functional defect are discussed. A review of recent publications on free functional muscle transfer in the lower extremity was also performed.
    Good functional recovery with a Medical Research Council grade of up to 4/5 and full range of motion can be attained with free functional muscle transfer. Clinical outcomes and specific parameters for published case series in lower extremity free functional muscle transfer are presented and an illustrative case.
    Free functional muscle transfer is a suitable treatment for the appropriate patient to restore essential functions and potentially regain ambulation. However, additional published clinical outcomes are needed and represent a major area for further investigation.
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  • 文章类型: English Abstract
    BACKGROUND: The functional deficits that develop after a peripheral nerve injury mean a considerable reduction in the quality of life for the affected patients. However, interventions on the injured nerve are not always possible or effective. In this case, secondary procedures, e.g. tendon transfers, are a feasible option for functional reconstruction.
    OBJECTIVE: An overview of the most common secondary surgical procedures for functional reconstruction after peripheral nerve injuries.
    METHODS: Presentation and discussion of the most common secondary surgical procedures with emphasis on tendon transfers. Illustration of the primary functions that need to be reconstructed depending on the respective nerve lesion.
    RESULTS: The basic principle of secondary surgical procedures after nerve injuries is the transposition of a healthy tendomuscular unit to replace a lost function following a loss of muscle or tendon or if an intervention on the nerve is not promising. For example, by transferring flexor forearm muscles, wrist, finger and thumb extension can be reconstructed after radial nerve injury. By transposing the tibialis posterior muscle, dorsiflexion in the talocrural joint can be restored to enable the affected patient to walk safely without an orthosis.
    CONCLUSIONS: Secondary surgical procedures are a valuable option for functional reconstruction after nerve injury.
    UNASSIGNED: HINTERGRUND: Die nach einer peripheren Nervenverletzungen entstehenden funktionellen Defizite bedeuten für die betroffenen Patienten eine erhebliche Einschränkung der Lebensqualität. Jedoch sind Eingriffe am verletzten Nerv nicht immer möglich oder zielführend. Motorische Ersatzoperationen stellen in diesem Fall eine sinnvolle Option zur funktionellen Rekonstruktion dar.
    UNASSIGNED: Übersicht über die gängigsten sekundären operativen Verfahren zur funktionellen Rekonstruktion nach Verletzungen peripherer Nerven.
    METHODS: Darstellung und Diskussion der gängigsten sekundären operativen Verfahren mit Schwerpunkt auf Sehnentransfers. Veranschaulichung der primär zu rekonstruierenden Funktionen abhängig von der jeweiligen Nervenläsion.
    UNASSIGNED: Das Grundprinzip sekundärer operativer Verfahren nach Nervenverletzungen ist die Transposition einer gesunden tendomuskulären Einheit zum Ersatz einer verlorenen Funktion, wenn es zum Verlust von Muskeln oder Sehnen gekommen oder ein Eingriff am Nerv nicht erfolgversprechend ist. Durch einen Transfer beugeseitiger Unterarmmuskeln können beispielsweise die Handgelenks‑, Finger- und Daumenextension nach einer Verletzung des N. radialis rekonstruiert werden. Durch die Transposition des M. tibialis posterior kann die Dorsalextension im oberen Sprunggelenk wiederhergestellt werden, um den betroffenen Patienten einen sicheren Gang ohne Orthese zu ermöglichen.
    UNASSIGNED: Motorische Ersatzoperationen stellen eine wertvolle Option zur funktionellen Rekonstruktion nach Nervenverletzungen dar.
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  • 文章类型: Journal Article
    背景:软组织功能重建对于股骨近端置换肿瘤切除后髋关节功能的恢复具有重要意义。这项研究评估了在股骨近端肿瘤切除术中用于软组织功能重建的特定合成韧带的功能结果和术后并发症。
    方法:该队列包括80名患者(40名男性和40名女性,平均年龄,40年(范围,10至79)患有良性浸润性肿瘤(n=13),原发性恶性骨肿瘤(n=40),或骨转移(n=27)。病人的医疗记录,映像文件,手术细节,收集术后病理诊断。按照Enneking分期标准进行肿瘤分期。使用肌肉骨骼肿瘤协会(MSTS)评分系统和Harris髋关节评分评估下肢和髋关节功能,分别。
    结果:术后平均MSTS和Harris评分为27(范围,24到30)和90(范围,76至97),分别,显示令人满意的运动范围和稳定性。在三名骨肉瘤患者(3.8%)中观察到Trendelenburg步态,6例患者下肢长度不等。5例发生再次手术,其中深静脉血栓形成3例,巨细胞肉芽肿和假体周围感染各1例。有27例骨转移患者不需要再次手术。
    结论:采用股骨近端置换切除肿瘤的髋关节合成韧带重建与改善预后相关。它的实施显示出降低术后髋关节脱位和假体周围感染发生率的潜力,从而保证其未来的临床应用。
    BACKGROUND: Soft-tissue functional reconstruction is important for restoring hip function in proximal femoral replacement for tumor resection. This study evaluated the functional outcome and postoperative complications of a specific synthetic ligament for soft-tissue functional reconstruction in proximal femoral replacement for tumor resection.
    METHODS: This cohort included 80 patients (40 men and 40 women, mean age, 40 years (range, 10 to 79)) who had benign invasive tumors (n = 13), primary malignant bone tumors (n = 40), or bone metastases (n = 27). Patients\' medical records, imaging files, surgical details, and postoperative pathological diagnoses were collected. Tumor staging was performed with the Enneking staging criteria. Lower limb and hip functions were assessed using the Musculoskeletal Tumor Society scoring system and Harris Hip score, respectively.
    RESULTS: Mean postoperative Musculoskeletal Tumor Society and Harris Hip scores were 27 (range, 24 to 30) and 90 (range, 76 to 97), respectively, indicating satisfactory range of motion and stability. Trendelenburg gait was observed in 3 osteosarcoma patients (3.8%), and 6 patients showed unequal lower-limb lengths. Reoperations occurred in 5 cases, including 3 cases of deep vein thromboses and 1 case each of giant cell granuloma and periprosthetic infection. There were 27 patients who had bone metastases who did not require reoperation.
    CONCLUSIONS: The synthetic ligament reconstruction of the hip with proximal femoral replacement for tumor resection was associated with improved outcomes. Its implementation exhibits the potential to reduce postoperative incidences of hip dislocation and periprostheses infection, thereby warranting its prospective clinical application.
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