Free flaps

自由襟翼
  • 文章类型: Journal Article
    目的:本研究调查了下颌骨重建手术中由于髁突在颞下颌关节中定位不当而导致的不令人满意的结果。还提出了重建后髁突定位不满的系统分类方法。
    方法:对337例肿瘤切除和下颌骨血管化皮瓣重建患者进行回顾性分析。重建技术包括常规手术(43.3%)和3D技术指导程序(56.7%)。评估利用术前和术后CT扫描来评估矢状(S)和冠状(C)平面中的下颌垂直支长度(V)和con突对齐。因此,开发了髁突定位分类系统,缩写为VSC。它包括四个类:I类,适当的髁突重建;二级,短支长度;III类,矢状/冠状髁位置的一个或两个方面不满意;和IV类,两三个方面的不满。
    结果:髁突重建总成功率为85.16%。虽然没有统计学意义,3D辅助组的成功率(85.86%)略高于常规组(84.25%).就VSC分类而言,案件在第一类中的分布,II,III,和IV分别为287、4、9和37例,分别。值得注意的是,髁突脱位与缺损部位显著相关,特别是身体和髁(p<0.001,OR=49.734,95%CI12.995-190.342),和重建段的数量(p=0.025,OR=3.480,95%CI1.173-10.328)。
    结论:研究结果强调了准确重建方法的重要性,并揭示了髁突脱位中缺损部位和重建节段数量的含义。因此,我们提出了一个分类系统,以完善髁突定位评估,提高下颌骨重建的手术效果。
    OBJECTIVE: This study investigates the unsatisfactory outcomes observed in mandibular reconstruction procedures attributed to improper condylar positioning in the Temporomandibular Joint. It also proposes a systematic classification for post-reconstruction condylar positioning dissatisfaction.
    METHODS: A retrospective analysis was conducted on 337 patients who underwent tumor removal and mandibular reconstruction with vascularized osteocutaneous flaps. Reconstruction techniques included conventional surgery (43.3%) and 3D technology-guided procedures (56.7%). Evaluation utilized preoperative and postoperative CT scans to assess mandibular vertical ramus length (V) and condylar alignment in both sagittal (S) and coronal (C) planes. Accordingly, a classification system for condylar positioning was developed and abbreviated as VSC. It includes four classes: Class I, proper condylar reconstruction; Class II, short ramus length; Class III, one or two aspects of sagittal/coronal condylar positions dissatisfaction; and Class IV, two or three aspects dissatisfaction.
    RESULTS: The overall success rate for condylar reconstruction was 85.16%. Though not statistically significant, the success rate was marginally higher in the 3D-assisted group (85.86%) compared to the conventional group (84.25%). In terms of the VSC classification, the distribution of cases across Class I, II, III, and IV were 287, 4, 9, and 37 cases, respectively. Notably, condylar dislocation was significantly associated with the defect site, particularly the body and condyle (p < 0.001, OR = 49.734, 95% CI 12.995-190.342), and the number of reconstructed segments (p = 0.025, OR = 3.480, 95% CI 1.173-10.328).
    CONCLUSIONS: The findings highlight the importance of accurate reconstruction methods and reveal implications of the defect site and the number of reconstructed segments in condylar dislocation. Consequently, we propose a classification system to refine condylar positioning assessment and enhance surgical outcomes in mandibular reconstruction.
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  • 文章类型: Journal Article
    头颈癌(HNC)是全球第六大最常见的癌症。尽管烟草消费量普遍减少,因此暴露风险降低,但口咽鳞状细胞癌的发病率仍在增加。在过去的几十年中,在自由组织转移重建和机器人手术方面取得的进展已合并为具有头颈部游离穿支皮瓣的经口机器人重建。我们回顾并讨论了这种手术的适应症和禁忌症,以及潜在的限制细化。
    Head and neck cancer (HNC) is the sixth most common cancer across the world. Despite a general reduction in tobacco consumption and therefore reduction in risk exposure there has been an increasing incidence of oropharyngeal squamous cell carcinoma. Progress made in the past decades in free tissue transfer reconstruction and robotic surgery have merged into transoral robotic reconstruction with free perforator flaps for head and neck. We reviewed and discussed indications and contraindications for this type of procedure, as well as potential limits refinements.
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  • 文章类型: Journal Article
    背景技术早期发现游离皮瓣受损对于皮瓣的抢救至关重要。已经描述了各种自由皮瓣监测的方法,但是临床评估是所有评估的标准方法。在这项研究中,红外热成像在自由皮瓣监测中的作用进行了评估。材料与方法游离皮瓣手术患者,根据我们的机构方案,使用标准临床参数和红外热成像进行监测.使用术中和术后热图像的温度读数计算皮瓣与周围皮肤之间的平均温差(ΔT)。与标准临床方案相比,评估了红外热成像在皮瓣监测中的准确性。结果41例皮瓣纳入分析,其中五个襟翼受损。观察到平均温度差较高(平均值ΔT0.20-0.59与2.38-3.32)当襟翼损坏时,这种温度差甚至在临床症状出现之前就很明显了。发现静脉血栓形成的温度差(平均ΔT1.0-2.7)略低于动脉供血不足的温度差(平均ΔT2.1-4.4)。对于ΔT截止值为2°C,热相机的灵敏度为88.6%,特异性为98.9%,阳性预测值为93.9%,阴性预测值为97.7%。结论红外热成像是一种有价值的、无创的游离皮瓣监测客观工具。即使在临床上变得明显之前,它也可以检测到皮瓣受损(ΔT的增加值)。
    Background  Early detection of free flap compromise is critical for salvage of the flap. Various methods of free flap monitoring have been described, but clinical assessment is the standard method for among all. In this study, role of infrared thermography is evaluated for free flap monitoring. Materials and Methods  In patients undergoing free flap surgery, monitoring was done using standard clinical parameters and infrared thermography as per our institutional protocol. Mean temperature difference (∆T) between the flap and the surrounding skin was calculated using the temperature readings from the thermal images intra- and postoperatively. The accuracy of infrared thermography in flap monitoring was assessed in comparison to the standard clinical protocol. Results  Forty-one flaps were included in the analysis, out of which five flaps got compromised. It was observed that the mean temperature difference was higher (mean ∆T 0.20-0.59 vs. 2.38-3.32) when there was a flap compromise, and this temperature difference was evident even before the development of clinical signs. The temperature difference in venous thrombosis (mean ∆T 1.0-2.7) was found to be slightly lower than in arterial insufficiency (mean ∆T 2.1-4.4). For a ∆T cutoff value of 2°C, the thermal camera had a sensitivity of 88.6%, specificity of 98.9%, positive predictive value of 93.9%, and negative predictive value of 97.7%. Conclusion  Infrared thermography is a valuable and noninvasive objective tool in free flap monitoring, which can detect flap compromise (increasing value of ∆T) even before it becomes clinically evident.
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  • 文章类型: Journal Article
    背景:颌骨肿瘤疾病需要有效的治疗,通常涉及下颌的连续性切除。通过微血管骨瓣重建,如旋髂深动脉皮瓣(DCIA),是标准的。计算机辅助规划(CAD)提高了使用患者特异性CT图像来创建三维(3D)模型的重建精度。有关CAD计划的DCIA襟翼精度的数据很少。此外,准确性数据应与植入物的精确定位数据相结合,以实现良好的牙科修复。这项研究的重点是CAD计划的DCIA皮瓣的准确性和正确定位以进行假肢康复。
    方法:对CAD计划的DCIA皮瓣重建的下颌骨切除术后患者进行评估。术后X线片衍生的3D模型与CAD截骨位置计划中的3D模型对齐,angle,和皮瓣体积比较。为了评估DCIA皮瓣对假牙修复的适用性,在支撑区创建了一架飞机,并在DCIA皮瓣的中部创建了一架飞机。旋转下颌以闭合嘴,并测量两个平面之间的距离。
    结果:20例患者(12例男性,包括8名女性)。平均缺陷尺寸为73.28±4.87mm;11L缺陷,9个LC缺陷。计划与实际DCIA移植体积差为3.814±3.856cm²(p=0.2223).背侧截骨术与计划角度的偏差明显大于腹侧(p=0.035)。腹侧截骨术计划的DCIA移植与实际的DCIA移植之间的线性差异为1.294±1.197mm,背侧为2.680±3.449mm(p=0.1078)。牙轴与DCIA移植中部之间的差异范围为0.2mm至14.8mm。第一前磨牙区域的平均横向差为2.695±3.667mm。
    结论:CAD计划的DCIA皮瓣是重建下颌骨的解决方案。CAD计划可实现精确的重建,从而实现牙科植入物的放置和牙科修复。
    BACKGROUND: Tumorous diseases of the jaw demand effective treatments, often involving continuity resection of the jaw. Reconstruction via microvascular bone flaps, like deep circumflex iliac artery flaps (DCIA), is standard. Computer aided planning (CAD) enhances accuracy in reconstruction using patient-specific CT images to create three-dimensional (3D) models. Data on the accuracy of CAD-planned DCIA flaps is scarce. Moreover, the data on accuracy should be combined with data on the exact positioning of the implants for well-fitting dental prosthetics. This study focuses on CAD-planned DCIA flaps accuracy and proper positioning for prosthetic rehabilitation.
    METHODS: Patients post-mandible resection with CAD-planned DCIA flap reconstruction were evaluated. Postoperative radiograph-derived 3D models were aligned with 3D models from the CAD plans for osteotomy position, angle, and flap volume comparison. To evaluate the DCIA flap\'s suitability for prosthetic dental rehabilitation, a plane was created in the support zone and crestal in the middle of the DCIA flap. The lower jaw was rotated to close the mouth and the distance between the two planes was measured.
    RESULTS: 20 patients (12 males, 8 females) were included. Mean defect size was 73.28 ± 4.87 mm; 11 L defects, 9 LC defects. Planned vs. actual DCIA transplant volume difference was 3.814 ± 3.856 cm³ (p = 0.2223). The deviation from the planned angle was significantly larger at the dorsal osteotomy than at the ventral (p = 0.035). Linear differences between the planned DCIA transplant and the actual DCIA transplant were 1.294 ± 1.197 mm for the ventral osteotomy and 2.680 ± 3.449 mm for the dorsal (p = 0.1078). The difference between the dental axis and the middle of the DCIA transplant ranged from 0.2 mm to 14.8 mm. The mean lateral difference was 2.695 ± 3.667 mm in the region of the first premolar.
    CONCLUSIONS: The CAD-planned DCIA flap is a solution for reconstructing the mandible. CAD planning results in an accurate reconstruction enabling dental implant placement and dental prosthetics.
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  • 文章类型: Journal Article
    传统的胸前瓣是一种需要延长住院时间的两阶段手术,增加治疗成本以及患者的不适,并可能延迟辅助治疗。改良的三角肌皮瓣,作为一个单阶段程序,可以克服这些缺点。这是对三级医院前瞻性收集的临床数据的回顾性图表回顾。考虑在2017年7月至2021年7月期间在我们医院接受过胸前皮瓣重建颈部缺损的患者进行分析。我们用单级三角肌皮瓣展示了我们的结果,该皮瓣用于重建颈部的中型到大型缺损,以及适当的临床插图。这项研究得到了机构伦理委员会的批准(编号:IEC702-2021)。研究期间共有6例患者接受了单期三角肌皮瓣,其中五个是肿瘤外科缺陷,其中一人患有坏死性筋膜炎。在所有情况下,愈合和总体结果都是最佳的,没有皮瓣损失。在其中两个案例中,捐赠基地主要是关闭的,在其余的,使用了分层厚度的皮肤移植物。我们的结果重申了单级三角肌皮瓣在颈部大中型手术缺损的初次重建中的巨大实用价值,即使在这个免费组织转移的时代。
    在线版本包含补充材料,可在10.1007/s12070-024-04641-8获得。
    Conventional deltopectoral flap is a two-staged procedure that needs a prolonged hospital stay, adding to treatment cost as well as patient discomfort and may delay adjuvant treatment. A modified deltopectoral flap, as a single-stage procedure, can overcome these shortcomings. This is a retrospective chart review of prospectively collected clinical data from a tertiary care hospital. The patients who had undergone a deltopectoral flap for the reconstruction of the neck defects at our hospital between July 2017 and July 2021 were considered for analysis. We present our results with a single-stage deltopectoral flap that was used to reconstruct medium-to-large-size defects of the neck, along with clinical illustrations as appropriate. This study was approved by the Institutional Ethical Committee (number: IEC 702-2021). A total of six patients received single-stage deltopectoral flap during the study period, of which five were for oncosurgical defects, and one had necrotizing fasciitis. The healing and overall outcome were optimal in all cases, with no flap loss. In two of these cases, the donor site was closed primarily, and in the rest, a split-thickness skin graft was used. Our results reiterate the tremendous practical value of a single-stage deltopectoral flap in the primary reconstruction of medium- to large-sized surgical defects of the neck, even in this era of free tissue transfer.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-024-04641-8.
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  • 文章类型: Journal Article
    背景:可以通过口内入路(IOA)或口外入路(EOA)进行节段性下颌骨切除术和重建缺损。这两种方法都有优势,缺点,适应症,以及在选择时要考虑的禁忌症。
    目的:比较节段性下颌骨切除和腓骨游离皮瓣(FFF)微血管重建的IOA与EOA。
    方法:我们进行了一项回顾性队列研究,纳入了从2020年到2024年接受节段性下颌骨切除术和FFF微血管重建的51例患者,尤其是17例IOA患者和34例EOA患者,代表本研究的两组。临床特征,手术参数,并对患者预后进行评估。随访期间评估患者满意度和Derriford外观量表(DAS59)。
    结果:成釉细胞瘤是最常见的诊断(IOA管理52.9%,EOA管理70.6%);FFF通常定位为双桶(IOA管理94.1%,EOA管理88.2%)。与EOA组相比,IOA组的术中失血较少(平均差异[MD]=-112.2,95%置信区间[CI]:-178.9至-45.5,p=0.001),满意度得分较高(MD=1.3,95%CI:0.9至1.7,p<0.001),和较低的DAS59评分(MD=-0.5,95%CI:-0.7至-0.2,p<0.001)。
    结论:IOA和EOA都是安全可行的,具有相似的围手术期特征和术后结局。与接受EOA治疗的患者相比,接受IOA治疗的患者对美学结果更满意。在下颌骨FFF重建期间没有同时立即植入,FFF在缺陷部位稳定后,应始终将患者转介给植入医师和/或修复医师进行牙齿修复,以改善功能和美学结果。
    BACKGROUND: Segmental mandibulectomy and reconstruction of resulting defect can be performed via intraoral approach (IOA) or extraoral approach (EOA). Both approaches have advantages, disadvantages, indications, and contraindications to consider during their selection.
    OBJECTIVE: To compare IOA vs EOA of segmental mandibulectomy and microvascular reconstruction with fibula free flap (FFF).
    METHODS: We conducted a retrospective cohort study in which 51 patients who underwent segmental mandibulectomy and microvascular reconstruction with FFF from 2020 to 2024 were included, especially 17 patients by IOA and 34 patients by EOA, representing both groups of this study. Clinical characteristics, surgery parameters, and patients\' prognosis were evaluated. Patients\' satisfaction and Derriford Appearance Scale (DAS59) were assessed during follow-up.
    RESULTS: Ameloblastoma was the most frequent diagnosis (52.9% managed by IOA vs 70.6% by EOA); FFF was frequently positioned as double barrel (94.1% managed by IOA vs 88.2% by EOA). Compared with EOA group, IOA group had less intraoperative blood loss (mean difference [MD] = -112.2, 95% confidence interval [CI]: -178.9 to -45.5, p = 0.001), higher satisfaction score (MD = 1.3, 95% CI: 0.9 to 1.7, p ˂ 0.001), and lower DAS59 score (MD = -0.5, 95% CI: -0.7 to -0.2, p ˂ 0.001).
    CONCLUSIONS: Both IOA and EOA were found safe and feasible, presenting similar perioperative features and postoperative outcomes. Patients managed with IOA were more satisfied with aesthetic outcomes than patients managed with EOA. In the absence of simultaneous immediate implant during mandibular FFF reconstruction, after stability of FFF on the defect site, patients should always be referred to an implantologist and/or prosthodontist for teeth restoration to improve functional and aesthetic outcomes.
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  • 文章类型: Journal Article
    目的:描述我们使用嵌合皮瓣的经验,并评估嵌合皮瓣与多个皮瓣相比的手术结果和术后并发症。
    方法:对2016年6月至2023年10月期间接受嵌合和多重同时游离组织移植的患者进行回顾性分析。感兴趣的主要结果是并发症发生率。重大并发症需要带回手术室,医院再入院,或转移到重症监护室。保守处理轻微并发症。次要结果包括手术时间,住院时间,皮瓣存活。
    方法:学术三级护理中心。
    结果:我们的分析包括113名患者(嵌合n=38,倍数n=75)。我们发现手术时间或次要并发症没有显着差异。嵌合皮瓣与住院时间较短有关。嵌合皮瓣的主要并发症发生率较高(42.1%vs22.7%,P=.03),但每个队列只有1例皮瓣全损.
    结论:大型头颈部缺损的复杂性对微血管外科医师提出了重建挑战。我们的发现表明,适当使用嵌合和多个皮瓣都会产生可接受的并发症率。并发症发生率的差异可能反映了利用率的差异。嵌合皮瓣仍然是一个有价值的选择,为那些先前的放射或根治性切除,但目前尚不清楚它们在多大程度上降低了该人群术后并发症的固有风险.必须根据患者的重建情况和机构的手术能力来权衡每种技术,以优化长期结果。
    OBJECTIVE: To describe our experience with chimeric flaps and to assess the surgical outcomes and postoperative complications associated with chimeric flaps compared to multiple flaps.
    METHODS: Patients undergoing chimeric and multiple simultaneous free tissue transfer between June 2016 and October 2023 were retrospectively reviewed. The primary outcome of interest was the complication rate. Major complications required takeback to the operating room, hospital readmission, or transfer to the intensive care unit. Minor complications were managed conservatively. Secondary outcomes included operative time, length of hospitalization, and flap survival.
    METHODS: Academic tertiary care center.
    RESULTS: Our analysis included 113 patients (chimeric n = 38, multiple n = 75). We found no significant difference in operative times or minor complications. Chimeric flaps were associated with a shorter length of hospitalization. The major complication rate was higher for chimeric flaps (42.1% vs 22.7%, P = .03), but each cohort only had 1 instance of total flap loss.
    CONCLUSIONS: The complexity of large head and neck defects poses a reconstructive challenge for microvascular surgeons. Our findings suggest that chimeric and multiple flaps both produce acceptable complication rates when used appropriately. Differences in complication rates may reflect differences in utilization. The chimeric flap remains a valuable option for those with prior radiation or radical resection, but it remains unclear the degree to which they lessen the inherent risk of postoperative complications within this population. Each technique must be weighed in context of the patient\'s reconstructive profile and the institution\'s surgical capabilities to optimize long-term outcomes.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    术中吲哚菁绿荧光血管造影(ICGFA)灌注评估已被证明可以减少重建手术的并发症。本研究旨在通过定量方法推进ICGFA皮瓣灌注评估。
    接受带蒂和游离皮瓣重建的患者使用开放或内窥镜系统进行术中ICGFA皮瓣灌注评估。患者人口统计学,记录ICGFA的临床影响和结局.从ICGFA的录音来看,荧光信号质量,以及皮瓣和周围(对照)组织的流入/流出里程碑进行了事后计算量化,并在感兴趣区域(ROI)水平上进行了比较。进一步的软件开发旨在全瓣量化,度量计算和热图生成。
    15例患者在重建时接受了ICGFA评估(8例头颈部,6个乳房和1个会阴),包括10个游离皮瓣和5个带蒂皮瓣。在33.3%的病例中,视觉ICGFA解释改变了表上管理,4例皮瓣边缘修剪,1例患者再次吻合。一名患者术后皮瓣裂开。腹腔镜相机的使用证明是可行的,但记录的信号质量低于开放系统。使用既定的和新颖的指标,目的ICGFA信号ROI定量允许皮瓣和周围组织之间的灌注比较。通过计算所有像素和随后的输出汇总作为热图,证明了全皮瓣评估的可行性。
    该试验证明了ICGFA在几种重建应用中进行基于操作员和定量皮瓣灌注评估的可行性和潜力。这些计算方法的进一步发展和实施需要技术和设备标准化。
    UNASSIGNED: Intraoperative indocyanine green fluorescence angiography (ICGFA) perfusion assessment has been demonstrated to reduce complications in reconstructive surgery. This study sought to advance ICGFA flap perfusion assessment via quantification methodologies.
    UNASSIGNED: Patients undergoing pedicled and free flap reconstruction were subjected to intraoperative ICGFA flap perfusion assessment using either an open or endoscopic system. Patient demographics, clinical impact of ICGFA and outcomes were documented. From the ICGFA recordings, fluorescence signal quality, as well as inflow/outflow milestones for the flap and surrounding (control) tissue were computationally quantified post hoc and compared on a region of interest (ROI) level. Further software development intended full flap quantification, metric computation and heatmap generation.
    UNASSIGNED: Fifteen patients underwent ICGFA assessment at reconstruction (8 head and neck, 6 breast and 1 perineum) including 10 free and 5 pedicled flaps. Visual ICGFA interpretation altered on-table management in 33.3% of cases, with flap edges trimmed in 4 and a re-anastomosis in 1 patient. One patient suffered post-operative flap dehiscence. Laparoscopic camera use proved feasible but recorded a lower quality signal than the open system.Using established and novel metrics, objective ICGFA signal ROI quantification permitted perfusion comparisons between the flap and surrounding tissue. Full flap assessment feasibility was demonstrated by computing all pixels and subsequent outputs summarisation as heatmaps.
    UNASSIGNED: This trial demonstrated the feasibility and potential for ICGFA with operator based and quantitative flap perfusion assessment across several reconstructive applications. Further development and implementation of these computational methods requires technique and device standardisation.
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  • 文章类型: Journal Article
    涉及颞下颌关节(TMJ)的半关节切除术缺损的修复具有挑战性。这项研究比较了半动脉切除术后使用和不使用虚拟计划的TMJ假体(TMJP)的深回旋动脉(DCIA)皮瓣的功能结果和重建准确性。评估了10例患者:5例使用TMJP(TMJP组),5例没有(对照组)。三维比较显示,带有TMJP的计划和实际DCIA皮瓣之间的平均偏差为0.11±0.04mm。计划和实际TMJP位置的高度相差0.56±0.57mm,腹侧/背侧0.33±0.24mm,内侧/外侧为1.18±0.42mm。张口,laterotrusion,对照组和中线偏差明显大于TMJP组(P=0.024,P=0.008,P=0.024)。DCIA皮瓣的腹侧到背侧平移的偏差略高于文献中的报道值,而高度偏差具有可比性。文献中的偏差较低是由于在两个TMJ都完好无损的情况下使用了DCIA瓣。实际上,内部计划的带有库存TMJP的DCIA皮瓣产生的结果可与更昂贵的患者专用假体相媲美。
    The repair of hemimandibulectomy defects involving the temporomandibular joint (TMJ) is challenging. This study compared the functional outcomes and reconstruction accuracy using a deep circumflex iliac artery (DCIA) flap with and without a virtually planned stock TMJ prosthesis (TMJP) after hemimandibulectomy. Ten patients were assessed: five with a TMJP (TMJP group) and five without (control group). A three-dimensional comparison revealed a mean deviation of 0.11 ± 0.04 mm between the planned and actual DCIA flap with TMJP. The planned and actual TMJP positions differed by 0.56 ± 0.57 mm in height, 0.33 ± 0.24 mm ventrally/dorsally, and 1.18 ± 0.42 mm medially/laterally. Mouth opening, laterotrusion, and midline deviation were significantly greater in the control group than in the TMJP group (P = 0.024, P = 0.008, P = 0.024). The deviation in ventral to dorsal translation for the DCIA flap was slightly higher than reported values in the literature, while height deviation was comparable. Lower deviations in the literature were due to the DCIA flap being used where both TMJs were intact. The in-house virtually planned DCIA flap with stock TMJP yielded results comparable to more expensive patient-specific prostheses.
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