Forestier Disease

包膜病
  • 文章类型: Review
    Anterior cervical osteophytes are a fairly common X-ray finding in people over 50 years old. Incidence of dysphagia in patients with anterior osteophytes varies from 1% in those aged 40-60 years to 10.6% in patients over 60 years old. The most common causes of anterior cervical hyperosteophytosis causing dysphagia are cervical spondylosis deformans and Forestier disease. We present 2 clinical cases of spondylogenic dysphagia in cervical spondylosis deformans and Forestier disease. The review is devoted to the causes and diagnostic methods for dysphagia caused by anterior cervical osteophytes, as well as surgical options for this pathology.
    CONCLUSIONS: Microsurgical resection of anterior osteophytes is an effective method for dysphagia after ineffective therapy for 3 months. Microsurgical osteophytectomy provides stable regression of dysphagia with low recurrence rate.
    Передние шейные остеофиты — довольно частая рентгенологическая находка у людей старше 50 лет. Частота дисфагии у пациентов с передними остеофитами варьирует в зависимости от возраста: от 1% в возрасте 40—60 лет до 10,6% — старше 60. Двумя наиболее частыми причинами переднего шейного гиперостеофитоза, вызывающего дисфагию, являются цервикальный деформирующий спондилез (ЦДС) и болезнь Форестье (БФ). В статье приведены описания двух клинических случаев спондилогенной дисфагии при БФ и ЦДС. В обзоре литературы проанализированы причины и методы диагностики дисфагии, вызванной передними шейными остеофитами, а также рассматриваются хирургические опции коррекции этой патологии.
    UNASSIGNED: При неэффективном консервативном лечении в течение 3 мес микрохирургическая резекция передних остеофитов является эффективным методом лечения дисфагии. Микрохирургическая остеофитэктомия обеспечивает стойкий регресс дисфагии при низкой частоте рецидивов.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    弥漫性特发性骨骼肥大(DISH)是一种导致韧带插入部位骨骼异常生长的疾病,主要在脊柱。病因不明,通常影响老年男性。它通常是无症状的,但如果影响颈椎前路,有时会导致吞咽困难。我们报告了一名50岁的DISH男性患者的病例,该患者患有慢性吞咽困难,并被诊断为颈部骨赘压迫食道。病人有几种合并症的病史,包括糖尿病,高血压,中风,还有痛风.他接受了骨赘的手术切除,恢复良好。我们讨论临床特征,诊断,以及DISH这种罕见并发症的治疗选择。
    Diffuse idiopathic skeletal hyperostosis (DISH) is a condition that causes abnormal bone growth at the sites of ligament insertion, mainly in the spine. It is of unknown etiology and usually affects older males. It is often asymptomatic, but it can sometimes cause dysphagia if it affects the anterior cervical spine. We report the case of a 50-year-old male patient with DISH who presented with chronic dysphagia and was diagnosed with a large cervical osteophyte compressing the esophagus. The patient had a history of several comorbidities, including diabetes, hypertension, stroke, and gout. He underwent surgical removal of the osteophyte and recovered well. We discuss the clinical features, diagnosis, and treatment options for this rare complication of DISH.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    Zenker憩室是起源于咽食管交界处的粘膜和粘膜下层的获得性囊状外袋。Zenker憩室的主要症状是吞咽困难。视频透视检查证实了诊断。前兆疾病是一种临床实体,其特征是前外侧椎骨韧带骨化和沿前外侧脊柱的前骨赘形成。其病因尚不清楚,常见症状是吞咽困难,发声困难和气道阻塞。这项研究的目的是确定Forestier疾病与Zenker憩室发作之间的病理生理相关性。
    进行了一项回顾性观察性研究。我们的放射科的电子数据库进行了分析,以确定患者下咽憩室和骨赘在颈椎水平,从2010年1月到2021年1月。使用精确的关键字执行搜索。
    计算机数据库搜索概述了10项成像检查:5项视频荧光图和5项计算机断层扫描。在100%的案例中,吞咽困难是导致诊断评估的主要症状;30%的患者,另一方面,报告呼吸困难。从数据分析来看,男女比例为1:1,患者平均年龄为64.8(+/-11.31)岁.
    我们假设Forestier疾病的解剖异常可能导致咽部压力增加,从而支持Zenker憩室的发展。因此,它总是建议调查Zenker憩室的存在在一个病人的前兆疾病,特别是Zenker憩室的危及生命的并发症。
    UNASSIGNED: Zenker\'s diverticulum is an acquired sac-like outpouching of the mucosa and submucosa layers originating at the pharyngoesophageal junction. The predominant symptom of Zenker\'s diverticulum is dysphagia. Videofluoroscopy confirms the diagnosis. Forestier disease is a clinical entity characterized by ossification of anterolateral vertebral ligament and anterior osteophyte formation along the anterolateral spinal column. Its etiopathogenesis remains unknown and common symptoms are dysphagia, dysphonia and airway obstruction. The objective of this study is to identify a pathophysiological correlation between Forestier disease and the onset of Zenker\'s diverticulum.
    UNASSIGNED: A retrospective observational study was conducted. The electronic database of our Radiology Unit was analyzed in order to identify patients with hypopharyngeal diverticulum and osteophytes at the cervical vertebrae level, from January 2010 to January 2021. The search was performed using precise keywords.
    UNASSIGNED: The computerized database search outlined 10 imaging exams: 5 videofluorographies and 5 computed tomography scans. In 100% of the cases, dysphagia was the main symptom that led to the diagnostic assessment; 30% of patients, on the other hand, reported dyspnoea. From the data analysis, the male / female ratio is 1: 1 and the average age of the patients is 64.8 (+/- 11.31) years.
    UNASSIGNED: We assume that the anatomical abnormalities in Forestier disease may cause an increase of pharyngeal pressure and consequently support the development of the Zenker\'s diverticulum. Hence, it is always recommended to investigate the presence of Zenker\'s diverticulum in a patient with Forestier disease, especially for the life-threatening complications of Zenker\'s diverticulum.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    前兆疾病是一种以韧带钙化和骨化为特征的疾病,尤其是影响轴向骨骼的韧带和牙齿。诊断很困难,需要高度怀疑,但在这些具有挑战性的临床情况下,像简单的X线摄影术这样的廉价且易于获得的检查可能提供有用的诊断线索,并改善临床辅助.
    Forestier disease is a condition characterized by calcification and ossification of ligaments and entheses particularly affecting axial skeleton. Diagnosis is difficult and mandates a high suspicion level, but unexpensive and accessible examinations like a simple radiography might provide useful diagnostic clues in these challenging clinical scenarios and improve clinical assistance.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

  • 文章类型: Journal Article
    弥漫性特发性骨骼骨肥大(DISH)是一种以颈椎韧带钙化和骨化为特征的疾病;在某些情况下,它可能会导致吞咽困难。这种情况在50岁以上有代谢紊乱的男性中更常见,它通常是无症状的,对患者来说不是主要问题。DISH的病因知之甚少,和已知的遗传因素表明多信号通路和多基因遗传。在这次审查中,我们讨论流行病学,临床,和DISH的病因学方面,特别关注吞咽困难。
    Diffuse idiopathic skeletal hyperostosis (DISH) is a condition characterized by the calcification and ossification of the ligaments of the cervical spine; in some cases, it may result in dysphagia. The condition is more common in men over 50 years of age with metabolic disorders, and it is often asymptomatic and not a major issue for patients. The etiology of DISH is poorly understood, and known genetic factors indicate multiple signal pathways and multigene inheritance. In this review, we discuss the epidemiological, clinical, and etiological aspects of DISH with a special focus on dysphagia.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

  • 文章类型: Case Reports
    Diffuse idiopathic skeletal hyperostosis (DISH) also known as Forestier disease is a noninflammatory, systemic skeletal disease of unknown etiology. DISH is usually asymptomatic but may compress the posterior wall of the aero digestive tract and lead to dysphagia, globus, hoarseness, stridor, dyspnea, and neurological problems. Although dysphagia is not uncommon among the presenting symptoms of DISH but dysphonia and stridor are rarely reported. We report a 68-year-old man who presented with a history of progressive dysphagia over 1 year and recent dysphonia and stridor secondary to cervical osteophytes. We discuss the symptoms, radiological features, and management of this uncommon case of DISH in conjunction with review of literature.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Case Reports
    UNASSIGNED: Diffuse idiopathic skeletal hyperostosis of cervical spine can lead to dysphagia.
    UNASSIGNED: A 73-year-old male weighing 110 kg and diagnosed with diffuse idiopathic skeletal hyperostosis in cervical spine with dysphagia. Patient manifested local pain of neck, a gradual limitation of spinal mobility. The surgery decision was based on swallowing problems, not pain in the spine. Before surgery radiographs, magnetic resonance images, computed tomography of the cervical spine and gastroscopy were obtained. Osteophytes were removed from the anterior approach with present otolaryngologist by surgery.
    UNASSIGNED: In this case used gastroscopy, CT and MRI for diagnostics. During the procedure we had support otolaryngologist. The patient has not been found a stenosis spinal canal and neurological symptoms. We were removed the ostheophytes. Interbody implants have not been applied.
    UNASSIGNED: Disc degeneration disease itself can be asymptomatic or not a dominant problem for the DISH patients. Clinical signs may pharyngoesophageal and tracheal compression, causing dysphagia, shortness of breath and stridor. In this case, the cervical spine was stability and not demonstrated a stenosis in the spinal canal. Isolate removing of the osteophytes without implants in DISH of cervical spine can be enough solution.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:功能轴和轴外减速和进行性关节痛,随后出现与肿胀相关的止痛步态,关节的僵硬和生理脊柱生物力学的丧失是该组患者的自然史。已对临床和放射学表型进行了仔细分析,以进一步了解其病因。
    方法:7名患者(3名9-11岁儿童和1名17岁儿童)。观察并检查了三名年龄分别为25、30、33和40岁的成年人。儿科组患者最初被诊断为肌病,后来在其他机构中被诊断为幼年类风湿性关节炎。我们部门收集了临床和影像学文件,然后是突变筛查,通过WISP3基因的双向测序进行。
    结果:临床和放射学表型研究证实了进行性假性类风湿软骨发育不良的诊断。一系列异常,例如早期老年脊柱肥厚症(Forestier疾病),髋部骨关节炎表现为进行性股骨骨phy发育不良和髋内翻相关的髋关节间隙逐渐缩小和不规则。功能缺失纯合突变(c.667T>G,p.Cys223Gly)和(c.170C>A,在我们的患者中鉴定了WISP3基因中的p.Ser57*)。
    结论:通过剧烈的肌病和风湿病检查不能明确诊断。详细的临床检查和骨骼调查,然后是基因型确认,是我们排除成年患者中幼年类风湿关节炎和类风湿多关节炎的误诊的基本指针。我们希望强调,临床/放射学表型是建立明确诊断并指导遗传学家正确基因型的基线工具。要点•关节疼痛和行走/爬楼梯的困难是儿童早期遇到的特征。在这一点上可以做出幼年类风湿性关节炎的错误诊断。•假阳性样肌肉萎缩类似肌病导致随后剧烈的麻烦调查。•与前端板骨化缺陷相关的椎体平坦化是进行性假性血管瘤样软骨发育不良的特征性特征。•接头膨胀,通常伴随着阑尾骨骼系统的关节末端变窄,显示了一个清晰的放射学表型的假性类风湿软骨发育不良。
    BACKGROUND: Axial and extra-axial deceleration in function and progressive joint pain with subsequent development of antalgic gait associated with swellings, and stiffness of the joints with loss of the physiological spine biomechanics were the natural history in this group of patients. Clinical and radiological phenotypes have been analysed carefully to further understand the aetiology behind.
    METHODS: Seven patients (three children around the age of 9-11 and one child of 17 years old). Three adults aging 25, 30, 33 and 40 years old were seen and examined. The paediatric group of patients were initially diagnosed with myopathy followed later by juvenile rheumatoid arthritis in other institutions. Clinical and imaging documentation were collected in our departments, followed by mutation screening, was carried out by bidirectional sequencing of the WISP3 gene.
    RESULTS: Clinical and radiological phenotypic studies confirmed the diagnosis of progressive pseudorheumatoid chondrodysplasia. A constellation of abnormalities such as early senile hyperostosis of the spine (Forestier disease), osteoarthritis of the hips showed progressive diminution and irregularities of the hip joint spaces associated with progressive capital femoral epiphyseal dysplasia and coxa vara have been encountered. Loss-of-function homozygous mutations (c.667T>G, p.Cys223Gly) and (c.170C>A, p.Ser57*) in the WISP3 gene were identified in our patients.
    CONCLUSIONS: The definite diagnosis was not defined via vigorous myopathic and rheumatologic investigations. Detailed clinical examination and skeletal survey, followed by genotypic confirmation, were our fundamental pointers to rule out the false diagnosis of juvenile rheumatoid arthritis and rheumatoid polyarthritis in the adult group of patients. We wish to stress that the clinical/radiological phenotype is the baseline tool to establish a definite diagnosis and to guide the geneticist toward proper genotype.Key Points•Joint pain and difficulties in walking/climbing the stairs are characteristic features encountered in early childhood. False diagnosis of juvenile rheumatoid arthritis can be made at this point.•False positive-like muscular wasting resembling myopathy results in ensuing vigorous troublesome investigations.•Flattened vertebral bodies associated with defective ossification of the anterior end plates are characteristic features of progressive pseudorheumatoid chondrodysplasia.•Joint expansions, which are usually accompanied by narrowing of the articular ends of the appendicular skeletal system, show a clear radiological phenotype of pseudorheumatoid chondrodysplasia.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

  • 文章类型: Case Reports
    Ossification of the anterior longitudinal ligament of the spine, known as Forestier disease or diffuse idiopathic skeletal hyperostosis, is usually an asymptomatic disorder. The area most frequently affected is the thoracic spine, followed by lumbar and cervical regions. In the case of cervical involvement with clinical manifestations, the most common symptoms include dysphagia, dyspnoea, dysphonia, and can exceptionally cause an acute airway obstruction. The airway management of these patients represents a great anaesthetic challenge. The case is reported of an eighty-five-year-old patient who had an acute airway obstruction associated with Forestier disease. A fibre-optic-assisted intubation was accomplished under sevoflurane inhaled anaesthesia, maintaining spontaneous ventilation, with subsequent tracheostomy performed by ENT surgeons.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Sci-hub)

公众号