未经证实:鞍区黄色肉芽肿是罕见的颅内病变,占所有鞍区病变的<1%。2000年,世界卫生组织将它们描述为一个单独的实体。由于文献报道的鞍状黄色肉芽肿病例很少,它们仍然是一个不确定来源的诊断挑战,临床课程,和结果。本研究报告了一例鞍状黄色肉芽肿,描述了临床表现,放射学/病理学特征,和结果。
未经授权:一位43岁的女性,已知患有糖尿病,甲状腺功能减退,多囊卵巢综合征,有2周的突然右侧面部偏斜史,眶周疼痛,和中等强度的头痛。患者还报告闭经未通过多囊卵巢综合征治疗得到改善。神经系统检查显示双侧视野缺损和视力受损。计算机断层扫描,没有对比,显示鞍区低密度病变,高密度区域。磁共振成像显示明确的鞍区病变,在T1加权和T2加权图像上显示高信号。患者接受了显微经鼻经蝶窦切除术。鞍区病变的组织学切片显示纤维结缔组织伴有慢性炎症细胞和胆固醇裂隙,提示黄色肉芽肿。病人目前正在神经外科随访,内分泌学,和眼科诊所定期进行实验室/放射学检查。
未经证实:鞍状黄色肉芽肿仍然是罕见的颅内病变,文献报道的病例很少。患者大多表现为严重的垂体功能减退和视觉功能障碍。它们没有特征性的放射学特征。诊断在组织病理学上得到证实,预后总体良好。
UNASSIGNED: Sellar xanthogranulomas are rare intracranial lesions comprising <1% of all sellar lesions. They were described as a separate entity by the World Health Organization in 2000. Because of the paucity of sellar xanthogranuloma cases reported in the literature, they remain a diagnostic challenge with indefinite origin, clinical course, and outcome. The present study reports a case of sellar xanthogranuloma describing the clinical presentation, radiological/pathological characteristics, and outcome.
UNASSIGNED: A 43-year-old female, known to have diabetes, hypothyroidism, and polycystic ovarian syndrome, presented with a 2-week history of sudden right-sided facial deviation, periorbital pain, and moderate-intensity headache. The patient also reported amenorrhea not improving with polycystic ovarian syndrome treatment. Neurologic examination showed bilateral visual field defects and impaired visual acuity. Computed tomography scan, without contrast, revealed a hypodense sellar lesion with areas of hyperdensity. Magnetic resonance imaging showed a well-defined sellar lesion, exhibiting high signals on T1-weighted and T2-weighted images. The patient underwent microscopic trans-nasal trans-sphenoidal excision of the lesion. Histological sections of the sellar lesion revealed
fibrous connective tissue with chronic inflammatory cells and cholesterol clefts, suggestive of xanthogranuloma. The patient is currently followed up at neurosurgery, endocrinology, and ophthalmology clinics with periodic laboratory/radiological investigations.
UNASSIGNED: Sellar xanthogranulomas remain rare intracranial lesions with few cases reported in the literature. Patients mostly present with severe hypopituitarism and visual dysfunction. They show no characteristic radiological features. The diagnosis is confirmed histopathologically, and the prognosis is generally favorable.