■自发性冠状动脉夹层(SCAD)是心肌梗死的非动脉粥样硬化原因。据报道,偏头痛在SCAD患者中很常见,但偏头痛相关残疾的程度尚未量化.
■临床数据和头痛变量来自前瞻性的基线评估,多中心iSCAD注册表。使用自我报告的偏头痛残疾评估(MIDAS)对偏头痛相关残疾进行量化。人口统计,临床,社会心理,比较了有偏头痛和无偏头痛患者的数据输入表格中的医学特征.
■在有可用数据的773名患者中,46%的人报告了以前或现在的偏头痛。偏头痛患者更有可能是女性(96.9%vs90.3%,p=0.0003)。潜在的颈动脉纤维肌肉发育不良的存在与偏头痛有关(35%vs27%,p=0.0175)。与颈动脉夹层和偏头痛没有显着关联。目前偏头痛频率低于每月(58%),每月(24%),每周(16%),和每日(3%)。据报道,32.5%的患者使用曲坦,17.5%的人每天使用偏头痛预防药物。使用MIDAS量化与偏头痛相关的残疾,60.2%报告很少或没有残疾,14.4%轻度,12.7%中等,和12.7%严重。平均MIDAS评分为9.9(轻度至中度残疾)。SCAD患者的抑郁和焦虑发生率更高(28.2%vs17.7%[p=0.0004]和35.3%vs26.7%[p=0.0099],分别)。
■偏头痛很常见,频繁,和SCAD患者的残疾来源。女性之间的联系,焦虑,和抑郁症可能为潜在的治疗方式提供一些见解。
UNASSIGNED: Spontaneous coronary artery dissection (SCAD) is a nonatherosclerotic cause of myocardial infarction. Migraine headache has been reported to be common among patients with SCAD, but the degree of migraine-related disability has not been quantified.
UNASSIGNED: Clinical data and headache variables were obtained from the baseline assessment of the prospective, multicenter iSCAD Registry. Migraine-related disability was quantified using the self-reported Migraine Disability Assessment (MIDAS). Demographic, clinical, psychosocial, and medical characteristics from data entry forms were compared between patients with and without migraine.
UNASSIGNED: Of the 773 patients with available data, 46% reported previous or current migraines. Those with migraines were more likely to be women (96.9% vs 90.3%, p = 0.0003). The presence of underlying carotid fibromuscular dysplasia was associated with migraine (35% vs 27%, p = 0.0175). There was not a significant association with carotid artery dissection and migraine. Current migraine frequency was less than monthly (58%), monthly (24%), weekly (16%), and daily (3%). Triptan use was reported in 32.5% of patients, and 17.5% used daily migraine prophylactic medications. Using the MIDAS to quantify disability related to migraine, 60.2% reported little or no disability, 14.4% mild, 12.7% moderate, and 12.7% severe. The mean MIDAS score was 9.9 (mild to moderate disability). Patients with SCAD had higher rates of depression and anxiety (28.2% vs 17.7% [p = 0.0004] and 35.3% vs 26.7% [p = 0.0099], respectively).
UNASSIGNED: Migraines are common, frequent, and a source of disability in patients with SCAD. The association between female sex, anxiety, and depression may provide some insight for potential treatment modalities.