Femoral Neuropathy

股神经病变
  • 文章类型: Journal Article
    背景:股外侧皮神经(LFCN)的压迫或损伤越来越频繁,通常需要手术方法来缓解症状。解剖变异的存在会导致诊断和术中决策的错误。
    方法:本研究提供了一名外科医生(T.W.T.)在处理184名与LFCN相关临床问题的患者方面的经验。对这些病例进行了全面审查,以制定前瞻性手术管理算法。LFCN解剖学课程的数据,疼痛缓解结果,合并症,身体质量指数,和性别是从患者的医疗图表和手术记录中提取的。疼痛缓解是主观评估的,归类为“极好的缓解”以完全消除疼痛,\“好\”对于大幅减轻疼痛和一些残留的不适,对于没有疼痛缓解需要再次手术的病例,则为“失败”。
    结果:根据LFCN病理的机制将决策树分为两分法:压迫(需要神经溶解)与外伤史,手术,和/或肥胖(需要切除)。该系列中有47%的患者有解剖变异。发现无法缓解压迫症状通常表明存在LFCN的解剖变异或神经内变化与神经瘤一致,即使实现了足够的减压。关于疼痛缓解作为结果衡量标准,LFCN解剖变异性的识别和该算法的使用产生了75%的优秀结果,10%的良好结果,15%的失败在36例失败中,有27例最初以神经溶解为手术方法。其中12次失败进行了第二次手术,LFCN神经切除术,导致10个优秀,1很好,和1持续失败。
    结论:本文建立了MP的手术治疗算法,结合临床经验和解剖学见解来指导治疗决策。考虑神经切除术的标准可能包括外伤史,先前的局部手术,解剖LFCN变化,慢性压迫造成的严重神经损伤.
    BACKGROUND: Entrapment or injury of the lateral femoral cutaneous nerve (LFCN) is being recognized with increasing frequency, often requiring a surgical approach to relieve symptoms. The presence of anatomic variations can lead to errors in diagnosis and intraoperative decision-making.
    METHODS: This study presents the experience of a single surgeon (T.W.T.) in managing 184 patients referred with clinical issues related to the LFCN. A comprehensive review of these cases was conducted to develop a prospective surgical management algorithm. Data on the LFCN\'s anatomic course, pain relief outcomes, comorbidities, body mass index, and sex were extracted from patients\' medical charts and operative notes. Pain relief was assessed subjectively, categorized into \"excellent relief\" for complete pain resolution, \"good\" for substantial pain reduction with some residual discomfort, and \"failure\" for cases with no pain relief necessitating reoperation.
    RESULTS: The decision tree is dichotomized based on the mechanism of LFCN pathology: compression (requiring neurolysis) versus history of trauma, surgery, and/or obesity (requiring resection). Forty-seven percent of the patients in this series had an anatomic variation. It was found that failure to relieve symptoms of compression often indicated the presence of anatomic variation of the LFCN or intraneural changes consistent with a neuroma, even if adequate decompression was achieved. With respect to pain relief as the outcome measure, recognition of LFCN anatomic variability and use of this algorithm resulted in 75% excellent results, 10% good results, and 15% failures. Twenty-seven of the 36 failures originally had neurolysis as the surgical approach. Twelve of those failures had a second surgery, an LFCN neurectomy, resulting in 10 excellent, 1 good, and 1 persistent failure.
    CONCLUSIONS: This article establishes an algorithm for the surgical treatment of MP, incorporating clinical experience and anatomical insights to guide treatment decisions. Criteria for considering neurectomy may include a history of trauma, prior local surgery, anatomical LFCN variations, and severe nerve damage due to chronic compression.
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  • 文章类型: Case Reports
    双侧股神经病很少见,尤其是由双侧髂腰肌压迫引起的,腰大肌,或者髂肌血肿.我们介绍了一例由于COVID-19危重病期间发生的自发性腰大肌血肿引起的双侧股神经病。一名41岁的患者患上了COVID-19肺炎,他的病情迅速恶化。血红蛋白水平的降低促使他在重症监护病房(ICU)住院期间进行影像学检查。双侧腰大肌血肿被确定为出血源。此后,患者主诉上下肢无力和下肢麻木。他被认为患有严重的神经病变,并被转介康复。电诊断测试表明,由于在ICU住院期间发生血肿引起的压迫,双侧股骨神经病变。在危重患者中发生髂腰肌血肿的后果可能是灾难性的,从失血性休克到严重的虚弱,强调承认这一实体的重要性。
    Bilateral femoral neuropathy is rare, especially that caused by bilateral compressive iliopsoas, psoas, or iliacus muscle hematomas. We present a case of bilateral femoral neuropathy due to spontaneous psoas hematomas developed during COVID-19 critical illness. A 41-year-old patient developed COVID-19 pneumonia, and his condition deteriorated rapidly. A decrease in the hemoglobin level prompted imaging studies during his intensive care unit (ICU) stay. Bilateral psoas hematomas were identified as the source of bleeding. Thereafter, the patient complained of weakness in both upper and lower limbs and numbness in the lower limb. He was considered to have critical illness neuropathy and was referred to rehabilitation. Electrodiagnostic testing suggested bilateral femoral neuropathy because of compression due to hematomas developed during the course of his ICU stay. The consequences of iliopsoas hematomas occurring in the critically ill can be catastrophic, ranging from hemorrhagic shock to severe weakness, highlighting the importance of recognizing this entity.
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  • 文章类型: Journal Article
    背景:这项研究的目的是评估有关美感异常(MP)的YouTube视频的可靠性,质量,以及质量水平之间的差异。
    方法:我们分析了59个与MP相关的视频。我们评估了几个视频特征,包括视图,喜欢,不喜欢,持续时间,和扬声器配置文件。我们使用了视角比率,像比率,视频功率指数(VPI),全球质量量表(GQS),JAMA标准,并修改了DISCERN(mDISCERN)以评估观众的参与度,人气,教育质量,和可靠性。
    结果:这些视频共获得4,009,141次观看次数(平均67,951.54次),25.4%的人专注于运动训练,23.7%的人专注于疾病信息。平均得分分别为mDISCERN2.4、GQS2.8和JAMA2.1。医生主导的视频有更高的mDISCERN分数,虽然盟军卫生工作者主导的视频有更多的观点,喜欢,不喜欢,视图比率,和VPI。低劣和高质量的视频在视图上有所不同,喜欢,视图比率,VPI,和持续时间。mDISCERN之间存在正相关,JAMA,和GQS分数,视频持续时间与GQS呈正相关。
    结论:讨论疾病的YouTube视频内容会显著影响观众的参与度和受欢迎程度。为了提高YouTube上有价值内容的可用性,缺乏同行评审过程,医疗专业人员必须提供适合其目标受众的高质量教育材料。
    BACKGROUND: The purpose of this study was to evaluate YouTube videos on meralgia paresthetica (MP) for reliability, quality, and differences between quality levels.
    METHODS: We analyzed 59 videos related to MP. We evaluated several video characteristics, including views, likes, dislikes, duration, and speaker profile. We used view ratio, like ratio, Video Power Index (VPI), Global Quality Scale (GQS), JAMA criteria, and modified DISCERN (mDISCERN) to assess viewer engagement, popularity, educational quality, and reliability.
    RESULTS: The videos received a total of 4,009,141 views (average 67,951.54), with 25.4% focused on exercise training and 23.7% focused on disease information. Mean scores were mDISCERN 2.4, GQS 2.8, and JAMA 2.1. Physician-led videos had higher mDISCERN scores, while allied health worker-led videos had more views, likes, dislikes, view ratios, and VPI. Poor and high-quality videos differed in views, likes, view ratio, VPI, and duration. Positive correlations existed among mDISCERN, JAMA, and GQS scores, with video duration positively correlated with GQS.
    CONCLUSIONS: The content of YouTube videos discussing diseases significantly influences viewer engagement and popularity. To enhance the availability of valuable content on YouTube, which lacks a peer review process, medical professionals must contribute high-quality educational materials tailored to their target audience.
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  • 文章类型: Journal Article
    感觉异常疼痛是一种常见的,但可能是由股外侧皮神经的功能障碍引起的未被认识的综合征。诊断基于患者对感觉障碍的描述,经常痛苦,在大腿前外侧,具有正常的力量和反应能力。感觉神经传导研究和体感诱发电位可用于支持诊断。但是两者都有技术限制,特异性和敏感性较低。感觉异常的风险因素包括肥胖,紧身衣服,和糖尿病。有些病例是髋关节或腰椎手术的并发症。大多数病例是自我限制的,但是一小部分患者仍然有难治性和致残症状。治疗选择包括治疗神经性疼痛的药物,神经溶解,神经切除术,和放射消融,但缺乏比较疗效的对照试验。
    Meralgia paresthetica is a common but probably underrecognized syndrome caused by dysfunction of the lateral femoral cutaneous nerve. The diagnosis is based on the patient\'s description of sensory disturbance, often painful, on the anterolateral aspect of the thigh, with normal strength and reflexes. Sensory nerve conduction studies and somatosensory evoked potentials may be used to support the diagnosis, but both have technical limitations, with low specificity and sensitivity. Risk factors for meralgia paresthetica include obesity, tight clothing, and diabetes mellitus. Some cases are complications of hip or lumbar spine surgery. Most cases are self-limited, but a small proportion of patients remain with refractory and disabling symptoms. Treatment options include medications for neuropathic pain, neurolysis, neurectomy, and radioablation, but controlled trials to compare efficacy are lacking.
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  • 文章类型: Journal Article
    股神经和闭孔神经都来自L2,L3和L4脊神经根,并下降到骨盆中,然后出现在下肢。股神经的主要功能是膝关节伸展和髋关节屈曲,以及腿部的一些感官神经支配。闭孔神经的主要功能是大腿内收和对大腿内侧小区域的感觉神经支配。每个人都可能受到各种潜在原因的伤害,其中许多是医源性的。这里,我们回顾了股神经和闭孔神经的解剖结构以及股神经和闭孔神经病变的临床特征和潜在病因。他们必要的调查,包括电诊断研究和成像,他们的预后,和潜在的治疗方法,在本章中讨论。
    The femoral and obturator nerves both arise from the L2, L3, and L4 spinal nerve roots and descend into the pelvis before emerging in the lower limbs. The femoral nerve\'s primary function is knee extension and hip flexion, along with some sensory innervation to the leg. The obturator nerve\'s primary function is thigh adduction and sensory innervation to a small area of the medial thigh. Each may be injured by a variety of potential causes, many of them iatrogenic. Here, we review the anatomy of the femoral and obturator nerves and the clinical features and potential etiologies of femoral and obturator neuropathies. Their necessary investigations, including electrodiagnostic studies and imaging, their prognosis, and potential treatments, are discussed in this chapter.
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  • 文章类型: Journal Article
    前交叉韧带(ACL)重建通常与中度至重度术后疼痛有关。值得注意的是,各种疼痛控制策略,股神经阻滞(FNB)与股外侧皮神经阻滞(LFCNB),带LFCNB的内收管阻滞(ACB),或关节周围鸡尾酒注射(PI),已被调查。然而,没有研究比较FNB与LFCNB的效果,带有LFCNB的ACB,和PI用于ACL重建后的疼痛控制。本研究旨在评估FNB对LFCNB的影响,带有LFCNB的ACB,和PI用于ACL重建后术后早期的疼痛缓解。
    这项回顾性对照临床试验纳入了299例患者,这些患者在2016年4月至2022年10月期间在我们医院接受了ACL重建。我们根据PI的使用将这些病例分为几组(PI组),带LFCNB的FNB(FNB组),ACB和LFCNB(ACB组)用于疼痛管理。我们每个选择了40个案例,以匹配的年龄,性别,和身体质量指数(BMI),分析120例。在FNB和ACB组中,术前超声引导下注射0.75%罗哌卡因15ml。在PI组中,0.75%罗哌卡因20毫升的混合物,生理盐水20毫升,地塞米松6.6mg在手术开始时注射一半,其余在伤口闭合前注射。患者人口统计学(年龄,性别,高度,体重,和BMI)和手术数据(半月板修复的要求,手术时间,和止血带充气时间)进行分析。ACL重建后,在术后30min和4,8,12,24,48和72h记录患者的数字疼痛评分(NRS)(0-10).然后使用方差分析比较三组之间的NRS。此外,在每个小组中,使用t检验在NRS≥7组和NRS≤6组之间比较这些数据.
    患者的人口统计学和手术数据没有显着差异。术后30minPI组疼痛评分明显高于FCB组和ACB组,但在术后12、24、48和72h时降低。在FNB组中,根据NRS疼痛评分,人口统计学和手术数据无显著差异.在ACB组中,NRS≥7组的男性人数明显高于NRS≤6组(p=0.015).在PI组中,NRS≥7组止血带充气时间明显长于NRS≤6组(p=0.008)。
    使用自体腿筋重建ACL后,与神经阻滞组合相比,关节周围鸡尾酒可显着减少术后早期疼痛。
    UNASSIGNED: Anterior cruciate ligament (ACL) reconstruction is commonly associated with moderate-to-severe postoperative pain. Notably, various pain control strategies, a femoral nerve block (FNB) with a lateral femoral cutaneous nerve block (LFCNB), adductor canal block (ACB) with LFCNB, or periarticular cocktail injection (PI), have been investigated. However, no studies compare the effects of FNB with LFCNB, ACB with LFCNB, and PI for pain control after ACL reconstruction. This study aimed to evaluate the impact of FNB with LFCNB, ACB with LFCNB, and PI for pain relief in the early postoperative period after ACL reconstruction.
    UNASSIGNED: This retrospective controlled clinical trial enrolled 299 patients who underwent primary ACL reconstruction at our hospital between April 2016 and October 2022. We categorized these cases into groups based on the use of PI (PI group), FNB with LFCNB (FNB group), and ACB with LFCNB (ACB group) for pain management. We selected 40 cases each, with matched age, sex, and body mass index (BMI) from each group, resulting in 120 cases for analysis. In the FNB and ACB groups, 0.75% ropivacaine 15 ml was injected under ultrasound guidance preoperatively. In the PI group, a mixture of 0.75% ropivacaine 20 ml, normal saline 20 ml, and dexamethasone 6.6 mg was injected half at the start of surgery and the rest just before wound closure. Patient demographics (age, sex, height, body weight, and BMI) and surgical data (the requirement for meniscal repair, operative time, and tourniquet inflation time) were analyzed. After ACL reconstruction, patients\' numerical rating scale pain scores (NRS) (0-10) were recorded at 30 min and 4, 8, 12, 24, 48, and 72 h postoperatively. NRS were then compared among the three groups using analysis of variance. In addition, within each group, these data were compared between the NRS ≥7 and NRS ≤6 groups using a t-test.
    UNASSIGNED: There were no significant differences in patient demographics and surgical data. Pain scores were significantly higher in the PI group than in the FCB and ACB groups 30 min postoperatively, but they were lower at 12, 24, 48, and 72 h postoperatively. In the FNB group, there were no significant differences in the demographic and surgical data by NRS pain score. In the ACB group, the number of men was significantly higher in the NRS ≥7 group than in the NRS ≤6 group (p = 0.015). In the PI group, tourniquet inflation time was significantly longer in the NRS ≥7 group than in the NRS ≤6 group (p = 0.008).
    UNASSIGNED: Following ACL reconstruction using a hamstring autograft, periarticular cocktail significantly reduced early postoperative pain compared with nerve block combinations.
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  • 文章类型: Journal Article
    感觉异常疼痛(MP)引起大腿外侧不适,麻木,还有刺痛.压迫或损伤外侧股皮神经(LFCN),对大腿的外部给予感觉神经支配。它经常被撞击在腹股沟韧带下方,导致LFCN分布的感觉受损。LFCN的压缩是MP的常见原因,而LFCN神经瘤是一种罕见的病因。此病例报告描述了由LFCN神经瘤产生的一种独特的感觉异常的Meralgia病例,并增强了我们对感觉异常的认识。
    Meralgia Paresthetica (MP) causes outer thigh discomfort, numbness, and tingling. Compression or injury to the Lateral Femoral Cutaneous Nerve (LFCN), which gives sensory innervation to outer aspect of the thigh. It frequently gets impinged beneath the inguinal ligament resulting in in sensory impairment in the distribution of LFCN. Compression of the LFCN is a frequent cause of MP, whereas LFCN neuromas is a rare cause. This case report describes a unique case of Meralgia Paresthetica produced by a LFCN neuroma and enhances our knowledge of Meralgia Paresthetica.
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  • 文章类型: Journal Article
    背景:Pavlik线束已用于治疗发育性髋关节发育不良(DDH)约一个世纪。股神经麻痹是使用Pavlik安全带的一种有记录的并发症,发病率从2.5%到11.2%不等。臂丛神经麻痹的罕见报道也有记录。本研究的主要目的是评估接受Pavlik线束治疗的DDH患者各种神经麻痹的发生率。次要目的是确定与神经麻痹相关的患者人口统计学或髋部特征。
    方法:我们对2016年2月1日至2023年4月1日在一家三级护理骨科医院诊断为DDH并接受Pavlik线束治疗的患者进行了回顾性研究。臀部偏侧,使用随后的刚性外展矫形器,出生顺序,臀位,体重,并收集了家族史。报告所有连续变量的中值(和四分位距[IQR])或平均值(和标准偏差[SD])。进行了独立的2样本t检验和Mann-WhitneyU检验,以确定在Pavlik线束治疗开始时收集的变量与神经麻痹的发生之间的关联。
    结果:纳入了350名患者(547髋)。22例股神经麻痹(占所有治疗髋关节的4%),臀下神经麻痹1例(0.18%),诊断为臂丛神经麻痹2例(0.37%)。根据Graf分类(p<0.001),神经麻痹患者的DDH更为严重,而通过Barlow和Ortolani动作进行体格检查时,DDH更为严重(p=0.003)。
    结论:在开始使用Pavlik线束时,神经麻痹与更严重的DDH相关。上肢和下肢神经状况应在治疗开始时和整个治疗过程中仔细检查,以评估神经麻痹。股骨的潜力,臀肌,和臂丛神经麻痹应包括在开始治疗时的风险讨论中。家庭可以放心,与Pavlik线束相关的神经麻痹有望在治疗短暂休息后解决。
    方法:治疗级别III。有关证据级别的完整描述,请参阅作者说明。
    BACKGROUND: The Pavlik harness has been used for approximately a century to treat developmental dysplasia of the hip (DDH). Femoral nerve palsy is a documented complication of Pavlik harness use, with an incidence ranging from 2.5% to 11.2%. Rare reports of brachial plexus palsy have also been documented. The primary purpose of the current study was to evaluate the incidence of various nerve palsies in patients undergoing Pavlik harness treatment for DDH. Secondary aims were to identify patient demographic or hip characteristics associated with nerve palsy.
    METHODS: We performed a retrospective review of patients diagnosed with DDH and treated with a Pavlik harness from February 1, 2016, to April 1, 2023, at a single tertiary care orthopaedic hospital. Hip laterality, use of a subsequent rigid abduction orthosis, birth order, breech positioning, weight, and family history were collected. The median (and interquartile range [IQR]) or mean (and standard deviation [SD]) were reported for all continuous variables. Independent 2-sample t tests and Mann-Whitney U tests were conducted to identify associations between the variables collected at the initiation of Pavlik harness treatment and the occurrence of nerve palsy.
    RESULTS: Three hundred and fifty-one patients (547 hips) were included. Twenty-two cases of femoral nerve palsy (4% of all treated hips), 1 case of inferior gluteal nerve palsy (0.18%), and 2 cases of brachial plexus palsy (0.37%) were diagnosed. Patients with nerve palsy had more severe DDH as measured by the Graf classification (p < 0.001) and more severe DDH as measured on physical examination via the Barlow and Ortolani maneuvers (p = 0.003).
    CONCLUSIONS: Nerve palsies were associated with more severe DDH at the initiation of Pavlik harness use. Upper and lower-extremity neurological status should be scrutinized at initiation and throughout treatment to assess for nerve palsies. The potential for femoral, gluteal, and brachial plexus palsies should be included in the discussion of risks at the beginning of treatment. Families may be reassured that nerve palsies associated with Pavlik harness can be expected to resolve with a short break from treatment.
    METHODS: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
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  • 文章类型: Journal Article
    目的:说明前入路全髋关节置换术(THA)后股神经病变患者的MRI表现。
    方法:本研究是对2010年1月1日至2022年7月1日在THA前路手术后接受MRI检查的患者进行的回顾性研究。纳入的患者没有先前存在的神经系统疾病。收集临床和诊断数据。2名肌肉骨骼放射科医师一致审查了MRI。
    结果:共审查了115份患者记录,其中17人被纳入最终分析(平均年龄64岁;11名女性)。研究对象表现为髋部屈曲和膝关节伸展的无力以及股神经分布的疼痛和麻木。在7个科目中,股神经表现正常。在五个科目中,在流体敏感性脂肪抑制成像中,股神经呈高强度.在4名患者中,通过任一不明确的软组织水肿对股神经的质量效应(n=2),血清肿(n=1),或异位骨化(n=1)被检测到。只有1例患者有神经横断。患者在关节成形术放置后的中位时间为8个月(范围:1天至11年)进行成像。8例患者均有临床随访,其中一半症状完全缓解,一半在平均随访39.3个月时部分改善(SD51.1)。在这8人中,1人接受了翻修关节成形术,1删除了硬件,另一个切除了异位骨化。
    结论:MRI提供了一种直接评估前入路THA术后即刻和慢性股神经的方法。
    OBJECTIVE: To illustrate MRI findings in patients with femoral neuropathy following anterior approach total hip arthroplasty (THA).
    METHODS: This was a retrospective review of patients who underwent MRI for femoral neuropathy following anterior approach THA between January 1, 2010, and July 1, 2022. Included patients had no preexisting neurologic condition. Clinical and diagnostic data were collected. MRIs were reviewed in consensus by 2 musculoskeletal radiologists.
    RESULTS: A total of 115 patient records were reviewed, 17 of which were included in the final analysis (mean age 64 years; 11 females). Study subjects presented with weakness with hip flexion and knee extension and pain and numbness in the femoral nerve distribution. In 7 subjects, the femoral nerve appeared normal. In 5 subjects, the femoral nerve was hyperintense on fluid-sensitive fat-suppressed imaging. In 4 patients, mass effect on the femoral nerve by either ill-defined soft tissue edema (n = 2), seroma (n = 1), or heterotopic ossification (n = 1) was detected. Only 1 patient had a nerve transection. Patients were imaged at a median time of 8 months (range: 1 day to 11 years) following arthroplasty placement. Clinical follow-up was available in 8 patients, of whom half had complete symptomatic resolution and half had partial improvement at a mean follow-up time of 39.3 months (SD 51.1). Of these 8, 1 underwent revision arthroplasty, 1 had removal of hardware, and another had excision of heterotopic ossification.
    CONCLUSIONS: MRI provides a means to directly evaluate the femoral nerve following anterior approach THA in both the immediate and chronic postoperative periods.
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  • DOI:
    文章类型: Case Reports
    感觉异常疼痛(MP)是一种由神经卡压或压迫引起的股外侧皮神经单神经病。它的特点是麻木,刺痛,大腿外侧的灼痛。目前MP的治疗包括常规的医疗管理,周围神经阻滞,和手术干预。一些患有MP的患者会经历顽固性疼痛,并且MP的医疗管理通常不足以提供令人满意的疼痛控制。虽然区域麻醉提供了极好的疼痛缓解,周围神经阻滞的镇痛作用是短暂的。新出现的证据表明,冷冻神经裂解具有低风险的安全性,并且在适当施用时可以延长浅表神经的疼痛缓解。我们介绍了一例成功的病例,该患者因接受冷冻神经溶解疗法治疗的MP引起的顽固性神经性疼痛。术后患者疼痛立即缓解100%,随访1个月和3个月时疼痛减轻80%和60%。分别。对于神经性疼痛的常规药物治疗失败的患者,冷冻神经溶解可能是一种替代方式。
    Meralgia paresthetica (MP) is a disorder of lateral femoral cutaneous nerve mononeuropathy caused by entrapment or compression of the nerve. It is characterized by numbing, tingling, and burning pain in the lateral aspect of the thigh. The current treatments for MP include conventional medical management, peripheral nerve blocks, and surgical interventions. Some patients who suffer from MP can experience intractable pain and medical management of MP is often inadequate to provide satisfactory pain control. Although regional anesthesia provides excellent pain relief, the analgesic effects of peripheral nerve block are short-lived. Emerging evidence suggests that cryoneurolysis has a low-risk safety profile and can provide prolonged pain relief of superficial nerves when administered appropriately. We present a successful case of a patient with intractable neuropathic pain resulting from MP treated with cryoneurolysis therapy. The patient demonstrated immediate pain relief by 100% after the procedure followed by 80% and 60% pain reduction at 1-month and 3-months follow-up, respectively. Cryoneurolysis may be an alternative modality for patients who fail at conventional medical treatments of neuropathic pain.
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