随着现代生活的快节奏,人们吃饭的时间更少,但是很少有研究研究过快速饮食习惯与代谢性疾病之间的关联。
结合当前研究和先前研究的结果,我们旨在探讨快速饮食与代谢功能障碍相关脂肪变性肝病(MASLD)风险之间的可能关系.
这是对1965名参与者的多中心横断面研究的子分析,调查了中国人快速饮食与MASLD之间的关联。快速进食被定义为用餐时间少于五分钟,参与者根据他们自我报告的快速进食频率分为三类:≤1次/月,≤1次/周且≥2次/周。我们进一步对11月之前发表的可用研究进行了文献检索,2023年以及一项荟萃分析,以调查快速饮食与MASLD之间的关系。
MASLD的比例为59.3%,50.5%,46.2%的参与者快速进食≥2次/周,≤1次/周,≤1次/月,分别(趋势P<0.001)。在多次调整性别后,快速进食的频率与MASLD的风险独立相关,年龄,人口统计,吸烟和饮酒状况,BMI和临床代谢参数(OR,1.29;95CI,1.09-1.53)。频繁进食(≥2次/周)的参与者发生MASLD的风险高81%(P=0.011)。对五项符合条件的研究进行的荟萃分析证实,频繁的快速进食与MASLD的风险增加有关(汇总OR,1.22;95CI,1.07-1.39)。
频繁的快速进食与MASLD的风险增加有关。
With the fast pace of modern life, people have less time for meals, but few studies have examined the association between the habit of fast eating and metabolic diseases.
Combining the results of the current study and the prior ones, we aimed to investigate the possible relationship between fast eating and the risk of metabolic dysfunction-associated steatotic liver disease (MASLD).
This is a sub-analysis of a multicenter cross-sectional study of 1965 participants investigated the association between fast eating and MASLD in Chinese. Fast eating was defined as meal time less than five minutes and participants were divided into three categories based on their self-reported frequency of fast eating: ≤1 time/month, ≤1 time/week and ≥2 times/week. We further conducted a literature search for available studies published before November, 2023 as well as a meta-analysis to investigate the association between fast eating and MASLD.
The proportion of MASLD was 59.3%, 50.5%, and 46.2% in participants with fast eating ≥2 times/week, ≤1 time/week and ≤1 time/month, respectively (P for trend <0.001). The frequency of fast eating was independently associated with risk of MASLD after multiple adjustment for sex, age, demographics, smoking and drinking status, BMI and clinical metabolic parameters (OR, 1.29; 95%CI, 1.09-1.53). Participants who ate fast frequently (≥2 times/week) had 81% higher risk of MASLD (P = 0.011). A meta-analysis of five eligible studies confirmed that frequent fast eating was associated with increased risk of MASLD (pooled OR, 1.22; 95%CI, 1.07-1.39).
Frequent fast eating was associated with an increased risk of MASLD.