Factores

  • 文章类型: Journal Article
    目的:探讨后交通动脉(Pcom)动脉瘤血管内栓塞治疗合并动眼神经麻痹(OMNP)的效果及影响治疗效果的因素。
    方法:回顾性纳入Pcom动脉瘤合并OMNP的患者进行动脉瘤的血管内治疗。所有患者均接受了血管内治疗。临床效果,OMNP的程度,动脉瘤的大小,治疗类型,蛛网膜下腔出血(SAH),分析从发病到治疗的时间对OMNP的分辨率。
    结果:纳入了96例Pcom动脉瘤患者,并进行了血管内治疗,成功率100%。血管内治疗后立即,75个动脉瘤(75.75%)完全闭塞,24例(24.24%)接近完全闭塞。随访3~18(平均8.52±0.56)个月,63例患者(65.63%)实现OMNP完全缓解,21的部分分辨率(21.88%),和其他12个(12.50%)未恢复。OMNP开始时的程度,SAH,从发病到治疗的时间与OMNP的消退有显著相关性(P<0.05)。单因素分析显示,患者年龄较小,OMNP发作时的程度,蛛网膜下腔出血的存在,从发病到治疗的时间与OMNP的恢复显著相关(P<0.05)。多变量分析表明,年龄越小,OMNP发作时的程度,从发病到治疗的时间与OMNP的恢复显著相关(P<0.05)。
    结论:血管内栓塞治疗伴OMNP的Pcom动脉瘤可有效改善OMNP症状。特别是对于中度和较短OMNP病史的患者。年龄更小,动眼神经麻痹发作时的程度,从发病到治疗的时间可能显著影响动眼神经麻痹的恢复。
    OBJECTIVE: To investigate the effect of endovascular embolization of posterior communicating artery (Pcom) aneurysms on concomitant oculomotor nerve palsy (OMNP) and factors affecting the effect of treatment.
    METHODS: Patients with the Pcom aneurysms concomitant with OMNP were retrospectively enrolled for endovascular treatment of the aneurysms. All patients had the endovascular management. The clinical effect, degree of OMNP, size of the aneurysm, type of treatment, subarachnoid hemorrhage (SAH), and time from onset to treatment were analyzed on the resolution of OMNP.
    RESULTS: Ninety-six patients with 99 Pcom aneurysms were enrolled and treated endovascularly, with the success rate of 100%. Immediately after endovascular treatment, 75 aneurysms (75.75%) got complete occlusion, and 24 (24.24%) nearly complete occlusion. Followed up for 3-18 (mean 8.52±0.56) months, complete resolution of the OMNP was achieved in 63 patients (65.63%), partial resolution in 21 (21.88%), and non-recovery in the other 12 (12.50%). The degree of OMNP at onset, SAH, and time from onset to treatment were significantly (P<0.05) correlated with the resolution of OMNP. Univariate analysis revealed that younger age of the patient, degree of OMNP at onset, presence of subarachnoid hemorrhage, and time from disease onset to treatment were significantly (P<0.05) associated with the recovery of OMNP. Multivariate analysis revealed that the younger age, degree of OMNP at onset, and time from disease onset to treatment were significantly (P<0.05) associated with the recovery of OMNP.
    CONCLUSIONS: Endovascular embolization of Pcom aneurysms concomitant with OMNP can effectively improve the OMNP symptoms, especially for patients with moderate and a shorter history of OMNP. Younger age, degree of oculomotor nerve palsy at onset, and time from onset to treatment may significantly affect recovery of oculomotor nerve palsy.
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  • 文章类型: Journal Article
    背景:患有2型糖尿病(DM2)的人与没有DM2的人相比,虚弱的患病率更高。然而,对于虚弱的DM2患者的诊断和临床治疗缺乏共识.
    目的:本研究旨在确定在PCDM2(患有DM2的人)中使用脆弱概念的局限性和当前需求,以及定义和评估应包括在其常规临床评估中的维度。
    方法:由来自西班牙不同医院的八名卫生专业人员组成的多学科团队参与了基于名义组技术的过程。
    结果:该研究确定了PCDM2弱点评估的八个限制,按重要性分类,和10个与疾病诊断和随访相关的未满足需求。此外,确定了7个维度,这些维度应包括在患有DM2的体弱者的定义中,按重要性和新颖性优先考虑。
    结论:本文旨在增加医学界DM2患者对脆弱概念的认识和使用。它还提出了未来项目制定针对该特定群体的脆弱共识定义的潜力。
    BACKGROUND: People with type 2 diabetes mellitus (DM2) have a higher prevalence of frailty compared to those without DM2. However, there is a lack of consensus on the diagnosis and clinical management of frail individuals with DM2.
    OBJECTIVE: This study aims to identify limitations and current needs in the use of the frailty concept in PCDM2 (people with DM2), as well as define and evaluate the dimensions that should be included in its routine clinical assessment.
    METHODS: A multidisciplinary team of eight health professionals from different hospitals in Spain participated in a process based on the nominal group technique.
    RESULTS: The study identified eight limitations in the assessment of frailty in PCDM2, categorized by importance, and 10 unmet needs related to the diagnosis and follow-up of the disease. Additionally, seven dimensions were identified that should be included in the definition of frail individuals with DM2, prioritized by importance and novelty.
    CONCLUSIONS: This article aims to increase knowledge and usage of the frailty concept in individuals with DM2 within the medical community. It also suggests the potential for future projects to develop a consensus definition of frailty tailored to this specific group.
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  • 文章类型: English Abstract
    目的:确定并优先考虑导致医院在家(HaH)专业人员工作量的因素列表。
    方法:2019年1月至12月在巴斯克地区的10个HAH单位进行了定性方法研究。数据分4个阶段获得:1。系统的文献检索和综述;2.专家组会议;3.共识法:德尔菲法(2轮调查)和名义小组会议;4.研究团队的会议。
    结果:在系统的文献检索和综述中,初步确定了85个因素。8人专家组会议后,这些减少到38人,其中增加了10个新因素。经过2轮德尔福(106和57名专业人员,分别),17个因素保持不变,12个因素仍有疑问。后者在名义上的小组会议上进行了评估,由13名专业人士组成,他们决定消除5个因素,包括3,并保留3作为怀疑。8人研究小组会议结束后,最终选择了14个潜在因素。它们与居住地有关,患者的健康状况和社会状况,以及在家提供的医疗保健。
    结论:确定的因素可以改善组织并优化HaH专业人员的日常工作。
    OBJECTIVE: To identify and prioritize a list of factors that contribute to the workload of the hospital at home (HaH) professionals.
    METHODS: A qualitative methodology study performed between January and December 2019 in the 10 HAH units of the Basque Country. The data were obtained in 4phases: 1. Systematic literature search and review; 2. Expert group meeting; 3. Consensus method: Delphi technique (2 survey rounds) and nominal group meeting; 4. Meeting of the research team.
    RESULTS: In the systematic literature search and review 85 factors were initially identified. These were reduced to 38 after the 8-person expert group meeting, in which 10 new factors were added. After the 2 Delphi rounds (106 and 57 professionals, respectively), 17 factors were maintained and 12 remained in doubt. The latter were evaluated at the nominal group meeting, consisting of 13 professionals who decided to eliminate 5 factors, include 3, and keep 3 as doubt. After the 8-person research team meeting, 14 potential factors were finally selected. They are related to the place of residence, the health state and social situation of the patients, as well as the health care provided at home.
    CONCLUSIONS: The identified factors could serve for improving the organization and optimize the daily word of the HaH professionals.
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  • 文章类型: Journal Article
    目的:探讨后交通动脉(Pcom)动脉瘤血管内栓塞治疗合并动眼神经麻痹(OMNP)的效果及影响治疗效果的因素。
    方法:回顾性纳入Pcom动脉瘤合并OMNP的患者进行动脉瘤的血管内治疗。所有患者均接受了血管内治疗。临床效果,OMNP的程度,动脉瘤的大小,治疗类型,蛛网膜下腔出血(SAH),分析从发病到治疗的时间对OMNP的分辨率。
    结果:纳入了96例Pcom动脉瘤患者,并进行了血管内治疗,成功率100%。血管内治疗后立即,75个动脉瘤(75.75%)完全闭塞,24例(24.24%)接近完全闭塞。随访3~18(平均8.52±0.56)个月,63例患者(65.63%)实现OMNP完全缓解,21的部分分辨率(21.88%),和其他12个(12.50%)未恢复。OMNP开始时的程度,SAH,从发病到治疗的时间与OMNP的消退有显著相关性(P<0.05)。单因素分析显示,患者年龄较小,OMNP发作时的程度,蛛网膜下腔出血的存在,从发病到治疗的时间与OMNP的恢复显著相关(P<0.05)。多变量分析表明,年龄越小,OMNP发作时的程度,从发病到治疗的时间与OMNP的恢复显著相关(P<0.05)。
    结论:血管内栓塞治疗伴OMNP的Pcom动脉瘤可有效改善OMNP症状。特别是对于中度和较短OMNP病史的患者。年龄更小,动眼神经麻痹发作时的程度,从发病到治疗的时间可能显著影响动眼神经麻痹的恢复。
    OBJECTIVE: To investigate the effect of endovascular embolization of posterior communicating artery (Pcom) aneurysms on concomitant oculomotor nerve palsy (OMNP) and factors affecting the effect of treatment.
    METHODS: Patients with the Pcom aneurysms concomitant with OMNP were retrospectively enrolled for endovascular treatment of the aneurysms. All patients had the endovascular management. The clinical effect, degree of OMNP, size of the aneurysm, type of treatment, subarachnoid hemorrhage (SAH), and time from onset to treatment were analyzed on the resolution of OMNP.
    RESULTS: Ninety-six patients with 99 Pcom aneurysms were enrolled and treated endovascularly, with the success rate of 100%. Immediately after endovascular treatment, 75 aneurysms (75.75%) got complete occlusion, and 24 (24.24%) nearly complete occlusion. Followed up for 3-18 (mean 8.52±0.56) months, complete resolution of the OMNP was achieved in 63 patients (65.63%), partial resolution in 21 (21.88%), and non-recovery in the other 12 (12.50%). The degree of OMNP at onset, SAH, and time from onset to treatment were significantly (P<0.05) correlated with the resolution of OMNP. Univariate analysis revealed that younger age of the patient, degree of OMNP at onset, presence of subarachnoid hemorrhage, and time from disease onset to treatment were significantly (P<0.05) associated with the recovery of OMNP. Multivariate analysis revealed that the younger age, degree of OMNP at onset, and time from disease onset to treatment were significantly (P<0.05) associated with the recovery of OMNP.
    CONCLUSIONS: Endovascular embolization of Pcom aneurysms concomitant with OMNP can effectively improve the OMNP symptoms, especially for patients with moderate and a shorter history of OMNP. Younger age, degree of oculomotor nerve palsy at onset, and time from onset to treatment may significantly affect recovery of oculomotor nerve palsy.
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  • 文章类型: Journal Article
    以前的研究似乎与COVID-19癌症患者的较高死亡率一致。入院时确定潜在的预后因素可以帮助识别预后不良的患者。
    我们的目的是在多中心国际注册中心(HOPECOVID-19)中探索住院的COVID-19癌症患者的特征和演变。我们的主要目标是确定那些特征,使我们能够识别预后较差的癌症患者(诊断出COVID-19后30天内死亡率)。
    在这个登记处收集了5838名患者,其中770人的前身是癌症。住院死亡率达到258例(33.51%)。中位数为75岁(65-82岁)。关于按性别分配,34.55%的患者(266/770)为女性。癌症类型的分布:泌尿生殖道238/745(31.95%),124/745(16.54%),血液学95/745(12.75%)。在多元回归分析中,入院时与死亡率独立相关的因素是:肾损害(OR3.45,CI97.5%1.85-6.58),心脏病(2.32,1.47-3.66),肝病(4.69,1.94-11.62),部分依赖(2.41,1.34-4.33),总依赖性(7.21,2.60-21.82),疲劳(1.84,1.16-2.93),关节痛(0.45,0.26-0.78),SatO2<92%(4.58,2.97-7.17),LDH升高(2.61,1.51-4.69)和血压异常降低(3.57,1.81-7.15)。分析参数也有显著改变。
    在HOPE注册的癌症患者中,任何原因导致的30天死亡率都很高,并且在到达医院时与易于识别的临床因素有关。识别这些患者可以帮助从一开始就开始更密集的治疗并评估这些患者的预后。
    Previous works seem to agree in the higher mortality of cancer patients with COVID-19. Identifying potential prognostic factors upon admission could help identify patients with a poor prognosis.
    We aimed to explore the characteristics and evolution of COVID-19 cancer patients admitted to hospital in a multicenter international registry (HOPE COVID-19). Our primary objective is to define those characteristics that allow us to identify cancer patients with a worse prognosis (mortality within 30 days after the diagnosis of COVID-19).
    5838 patients have been collected in this registry, of whom 770 had cancer among their antecedents. In hospital mortality reached 258 patients (33.51%). The median was 75 years (65-82). Regarding the distribution by sex, 34.55% of the patients (266/770) were women. The distribution by type of cancer: genitourinary 238/745 (31.95%), digestive 124/745 (16.54%), hematologic 95/745 (12.75%). In multivariate regression analysis, factors that are independently associated with mortality at admission are: renal impairment (OR 3.45, CI 97.5% 1.85-6.58), heart disease (2.32, 1.47-3.66), liver disease (4.69, 1.94-11.62), partial dependence (2.41, 1.34-4.33), total dependence (7.21, 2.60-21.82), fatigue (1.84, 1.16-2.93), arthromialgias (0.45, 0.26-0.78), SatO2<92% (4.58, 2.97-7.17), elevated LDH (2.61, 1.51-4.69) and abnormal decreased Blood Pressure (3.57, 1.81-7.15). Analitical parameters are also significant altered.
    In patients with cancer from the HOPE registry, 30-day mortality from any cause is high and is associated with easily identifiable clinical factors upon arrival at the hospital. Identifying these patients can help initiate more intensive treatments from the start and evaluate the prognosis of these patients.
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  • 文章类型: Journal Article
    UNASSIGNED: To analyze the factors attributable to the cancellation of surgeries of a third level health institution in the city of Valledupar, Cesar / Colombia (2017-2018).
    UNASSIGNED: Descriptive, retrospective, cross-sectional study. Data from the hospital surgical unit adverse case file were collected for 6 surgical specialties.
    UNASSIGNED: They showed that in 2017 there was a surgical suspension of 4% of the total of scheduled surgeries that were (3339), for 2018 the rate was 3% with a total of scheduled surgeries (1733). The reason for the suspension for both periods was the factor related to the patient\'s adverse conditions with 45.9 and 38.5% respectively. The specialty most affected for these cases was the specialty of general surgery with the same percentage value in both periods of 4%.
    UNASSIGNED: The results give us an idea of the factors present for the cancellation of scheduled surgeries and the need to apply measures to guarantee patient safety.
    UNASSIGNED: Analizar los factores atribuibles a la cancelación de cirugías de una institución de salud de tercer nivel en la ciudad de Valledupar, Cesar, Colombia (2017-2018).
    UNASSIGNED: Estudio descriptivo, retrospectivo, transversal. Se recopilaron datos del archivo de casos adversos de la unidad quirúrgica del hospital para 6 especialidades quirúrgicas.
    UNASSIGNED: Mostraron que en 2017 hubo una suspensión quirúrgica del 4% del total de cirugías programadas que fueron (3339), para 2018 la tasa fue del 3% con un total de cirugías programadas (1733). La razón de la suspensión para ambos períodos fue el factor relacionado con las condiciones adversas del paciente con 45.9 y 38.5% respectivamente. La especialidad más afectada para estos casos fue la especialidad de cirugía general con el mismo valor porcentual en ambos períodos del 4%.
    UNASSIGNED: Los resultados nos dan una idea de los factores presentes para la cancelación de cirugías programadas y la necesidad de aplicar medidas para garantizar la seguridad del paciente.
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  • 文章类型: Journal Article
    OBJECTIVE: Leadership communicates purpose and innovative ways to thrive for performance. Leadership support influences and impacts operational excellence in the health sector as a patient-centered operation, with effective management, excellence framework, challenges and constraints, teamwork and value stream mapping. It is hypothesized that: (1) perceived leadership support will positively correlate with perceived operational excellence (Patient-centered Operations, Effective Resource Management, Excellence framework, Eliminating Challenges or Constraints, Team Work, Value Stream Mapping) and (2) the correlation would be highest with Patient-centered Operations. The aim of this study was to examine the relationship between leadership support and operational excellence in the health care sector among a selected group of healthcare managers.
    METHODS: A correlation study between leadership support and operational excellence was designed for a group of health care managers (n=80) from eight hospitals in Kerala, South India. The selection of executives was from NABH accredited hospitals from districts with a minimum of four NABH accredited hospital. A survey was sent to a selected study sample. The respondents were cooperative and provided responses on perceived leadership support for operational excellence.
    RESULTS: Factors of leadership support correlated to operational excellence.
    CONCLUSIONS: In the health care sector, leadership support for patient-centered operations helps achieve operational excellence.
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