Facial nerve palsy

面神经麻痹
  • 文章类型: Case Reports
    贝尔氏麻痹是一种影响面神经的特发性和罕见的周围神经麻痹,导致无法控制受影响一侧面部表情的肌肉。本文介绍了两例接受全身性类固醇治疗的女性患者的单侧贝尔麻痹,抗病毒药物,和人工泪液替代品。治疗结果,临床课程,并详细讨论了恢复时间表。关于病因学的文献综述,诊断,贝尔氏麻痹的管理也提供了在更广泛的临床实践中对这些病例的背景。
    Bell\'s palsy is an idiopathic and uncommon peripheral nerve palsy that affects the facial nerve, leading to an inability to control the muscles of facial expression on the affected side. This paper presents two cases of unilateral Bell\'s palsy in female patients treated with systemic steroids, antiviral drugs, and artificial tear substitutes. The treatment outcomes, clinical course, and recovery timelines are discussed in detail. A review of the current literature on the etiology, diagnosis, and management of Bell\'s palsy is also provided to contextualize these cases within broader clinical practice.
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  • 文章类型: Case Reports
    脑膜中动脉栓塞(MMAE)已成为治疗新的或复发性慢性硬膜下血肿(CSDH)的安全有效的替代方法。即使在血管造影中没有明显危险的吻合,也可能突然发生一些并发症,例如面神经麻痹。我们在此提供MMAE后左面神经麻痹的病例报告。
    Middle meningeal artery embolization (MMAE) has emerged as a safe and efficacious alternative to surgery for the treatment of new or recurrent chronic subdural hematoma (CSDH). Several complications such as facial palsy may suddenly occur even in the absence of evident dangerous anastomoses in the angiogram. We herein present a case-report of left facial nerve palsy after MMAE.
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  • 文章类型: Journal Article
    我们分析了眨眼的动力学,并使用与临床特征和临床进展相关的眼表干涉仪定义了面神经麻痹(FNP)患者的眨眼指数。
    总共,49名患者参加了这项研究。所有患者均使用眼表干涉仪进行测试,该干涉仪用于测量眨眼模式(总眨眼(TB),部分眨眼率(PBR))和眨眼动态(眨眼时间(BT),盖子关闭时间(LCT),闭合时间(CT),盖子打开时间(LOT),闪烁时间(IBT),关闭速度(CS),andopeningspeed(OS))using600framesrecordedover20s.Thedistanceoflagnoosandmodifiedlapedlesure(IPF),定义为上眼睑的实际移动距离,从IPF中减去眼球的距离,使用ImageJ程序测量。FNP的类型为“特发性”(贝尔麻痹)和“外科”(神经外科手术后)。根据从FNP开始的6个月的持续时间,将患者分为“急性”和“慢性”。根据暴露性角膜病变的严重程度,将临床特征分为轻度或重度-如果需要治疗如tarsorrhy和金板插入,则为“严重”。
    降低MRD1,眉高,在麻痹侧发现改良的IPF和增加的眩眼。LCT较长,CS较长,修改后的CS,麻痹侧的改良OS较短。在急性发作和临床严重的特发性患者中,LCT更长,改良CS更短。临床严重的特发性患者IBT升高。
    分析眨眼模式和眨眼动力学,这项研究提出了眨眼轮廓和动力学中有意义的指标,LCT,并基于修改后的IPF修改CS。与FNP患者的手术类型相比,特发性类型的相关性更高。修饰的CS可以是评估FNP的活性和严重性指标的有用工具。
    UNASSIGNED: We analyzed the dynamics of blink and defined the blink index in facial nerve palsy (FNP) patients using an ocular surface interferometer associated with clinical characteristics and clinical progress.
    UNASSIGNED: In total, 49 patients were enrolled this study. All patients were tested using an ocular surface interferometer which is used to measure blink patterns (total blink (TB), partial blink rate (PBR)) and blink dynamics (blink time (BT), lid closing time (LCT), closure time (CT), lid opening time (LOT), interblink time (IBT), closing speed (CS), and opening speed (OS)) using 600 frames recorded over 20 s. The distance of lagophthalmos and modified interpalpebral fissure (IPF), which was defined as the actual moving distance of the upper eyelid, subtracting the distance of lagophthalmos from IPF, was measured using the ImageJ program. The types of FNP were \"idiopathic\" (Bell\'s palsy) and \"surgical\" (following the neurosurgery). Patients were classified into \"acute\" and \"chronic\" based on the duration of 6 months from the onset time of FNP. The clinical characteristics were classified into mild or severe according to the severe degree of exposure keratopathy-as \"severe\" if treatment such as tarsorrhaphy and gold plate insertion was required.
    UNASSIGNED: Reduced MRD1, brow height, and modified IPF and increased lagophthalmos were noted in the palsy side. LCT was longer and CS, modified CS, and modified OS were shorter in the palsy side. The LCT was longer and the modified CS was shorter in idiopathic patients with acute onset and with clinically severe. IBT was increased in idiopathic patients with clinically severe.
    UNASSIGNED: Analyzing the blink patterns and blink dynamics, this study suggests meaningful indicators among blink profiles and dynamics, LCT, and modified CS based on modified IPF. It was more associated in the idiopathic type than in the surgical type of FNP patients. The modified CS can be a useful tool for evaluating the activity and severity indicator of FNP.
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  • 文章类型: Journal Article
    我们报告了一例严重耳部感染的病例,该病例为一名35岁的男性患者,使用ixekizumab治疗牛皮癣。Ixekizumab是一种人源化单克隆抗体,可选择性阻止白介素17A及其受体之间的相互作用。像ixekizumab这样的生物制剂用于在包括牛皮癣的自身免疫性疾病中实现症状缓解。与通常描述为这种治疗副作用的轻度上呼吸道感染不同,我们报告了一例严重中耳炎的患者,并发面部轻瘫和鼻咽脓肿。据我们所知,这是第一个严重的案例,复杂的耳朵感染可能是ixekizumab的副作用。我们得出结论,当使用ixekizumab时,需要警惕上呼吸道感染,如有必要,应考虑中断治疗。然而,需要进一步的研究来证实这一假设。
    We report a case of a severe ear infection in a 35-year-old man treated with ixekizumab for psoriasis. Ixekizumab is a humanized monoclonal antibody that selectively prevents the interaction between interleukin 17 A and its receptor. Biologicals like ixekizumab are used to achieve symptom relief in autoimmune diseases including psoriasis. Unlike the mild upper respiratory tract infections usually described as side-effects of this treatment, we report a case of a patient who presented with a severe otitis media, complicated with a facial paresis and nasopharyngeal abscess. To the best of our knowledge, this is the first case presenting a severe, complicated ear infection as a possible side effect of ixekizumab. We conclude that when using ixekizumab, vigilance for upper airway infections is needed and if necessary, interruption of therapy should be considered. However, further research is needed to confirm this hypothesis.
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  • 文章类型: Journal Article
    背景:皮质类固醇治疗通常推荐用于急性面神经无力;然而,其治疗创伤性神经损伤的有效性仍存在争议。这项研究调查了面神经损伤后全身地塞米松给药的功能恢复和细胞作用。
    方法:C57BL/6小鼠腹腔注射分为磷酸缓冲盐水组和地塞米松组。引起面神经挤压伤,其次是恢复的功能分级。使用透射电子显微镜研究了细胞效应,流式细胞术,免疫荧光,和活体成像。
    结果:全身给予地塞米松可显著抑制巨噬细胞向面神经的浸润。然而,与PBS组相比,地塞米松组略微延迟了面神经的功能恢复。此外,伤后14天,两组神经的形态学变化无显著差异.活体成像中的巨噬细胞迁移分析也显示两组之间没有差异。
    结论:总之,全身地塞米松成功抑制白细胞浸润;然而,与PBS对照组相比,功能恢复延迟。临床上,这些发现表明,使用类固醇脉冲疗法治疗创伤性面神经损伤需要更多的证据和研究。
    BACKGROUND: Corticosteroid therapy is commonly recommended for acute facial nerve weakness; however, its effectiveness in treating traumatic nerve injuries remains controversial. This study investigated the functional recovery and cellular effects of systemic dexamethasone administration after facial nerve injury.
    METHODS: C57BL/6 mice were assigned to two groups by intraperitoneal injection: the phosphate-buffered saline group and the dexamethasone group. Facial nerve crush injury was induced, followed by the functional grading of recovery. Cellular effects were investigated using transmission electron microscopy, flow cytometry, immunofluorescence, and intravital imaging.
    RESULTS: Macrophage infiltration into the facial nerves was significantly inhibited by systemic dexamethasone administration. However, dexamethasone group slightly delayed the functional recovery of the facial nerve compared to the PBS group. In addition, the morphological changes in the nerve were not significantly different between the two groups at 14 days post-injury. Macrophage migration analysis in the intravital imaging also showed no difference between groups.
    CONCLUSIONS: In summary, systemic dexamethasone successfully inhibited leukocyte infiltration; however, functional recovery was delayed compared to the PBS control group. Clinically, these findings indicate that more evidence and research are required to use steroid pulse therapy for the treatment of traumatic facial nerve injuries.
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  • 文章类型: Journal Article
    目的:在腮腺手术的并发症中,面神经麻痹是常见的,并且对患者的功能和社会影响很大。关于腮腺手术后面神经肌肉再训练(FNR)对面神经麻痹患者的疗效的数据很少,并且没有关于其对恢复时间和程度的影响的数据。
    方法:对保留腮腺FN手术和术后面神经麻痹的患者进行了回顾性研究。在2016年7月至2023年5月期间接受手术的400名患者中,选择了保留FN和面神经麻痹发作的患者。使用House-Brackman(H&B)和Sunnybrook量表(SB)在2年的随访中评估神经功能。
    结果:共46例接受部分或全腮腺切除术的患者。出院时,根据H&B,18例患者(39,1%)患有IV至VI级瘫痪,平均SBs值为54。手术后2个月和6个月,Sunnybrook的平均值分别增加到76.5和95.4。12个月后,我们的队列中没有IV至VI级瘫痪的患者。手术两年后,根据HBs,只有5例患者(10.9%)出现持续性II级瘫痪.
    结论:我们的研究支持FNR在保留腮腺神经切除术后面瘫康复中的疗效。在康复的前6个月内实现了更大的功能改善。18个月后仍有显着改善,支持第一年后未完全康复的患者长期康复的重要性。
    OBJECTIVE: Among the complications of parotid surgery, facial palsy is frequent and burdened by high functional and social impact for the patient. There are few data on the efficacy of facial neuromuscular retraining (FNR) in patients with facial palsy after parotid surgery, and no data exist on its impact in timing and extent of recovery.
    METHODS: A retrospective study was conducted on patients undergoing FN sparing parotid surgery and suffering from postoperative facial palsy. Among 400 patients undergoing surgery between July 2016 and May 2023, those with the preservation of the FN and onset of facial palsy were selected. Nerve function was evaluated during 2 years follow up using the House-Brackman (H&Bs) and Sunnybrook scales (SBs).
    RESULTS: A total of 46 patients undergoing partial or total parotidectomy were included. At discharge 18 patients (39,1%) had IV to VI grade paralysis according to the H&Bs and the mean SBs value was 54. At 2 and 6 months after surgery, the average value of Sunnybrook increased to 76.5 and 95.4 respectively. After 12 months no patients with IV to VI grade paralysis were represent in our cohort. Two years after surgery, only five patients (10.9%) had persistent grade II paralysis according to HBs.
    CONCLUSIONS: Our study supports the efficacy of FNR in the rehabilitation of facial paralysis after nerve-sparing parotidectomy. The greater functional improvement is achieved within the first 6 months of rehabilitation. A significant improvement is detected still after 18 months, supporting the importance of long rehabilitation for patients without complete recovery after the first year.
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  • 文章类型: Case Reports
    急性化脓性中耳炎偶尔会导致面瘫,这需要及时诊断和治疗。面瘫,贝尔麻痹的同义词,是导致面部肌肉一侧快速减弱的一种情况,导致那一边的脸下垂。决定病情进程的主要因素是通过物理治疗进行康复。这里,我们介绍了一名26岁女性的病例,她在2024年2月21日左耳感到不适,但当时选择忽略.她观察到嘴里突然出现偏差,并参观了一家乡村医院,她被录取的地方.在检查过程中观察到面部不对称,她被发现在House-Brackmann量表上有V级.通过哑剧治疗开始了接近正常的肌肉动作,通过面部本体感觉神经肌肉促进和电刺激给予本体感觉刺激。所有这些方法都以显著的方式使患者受益。
    Acute suppurative otitis media can occasionally result in facial paralysis, which calls for prompt diagnosis and treatment. Facial paralysis, a synonym for Bell\'s palsy, is a condition that causes rapid weakening of one side of the face muscles, leading to drooping of the face on that side. A major factor in determining the course of the condition is rehabilitation through physiotherapy. Here, we present a case of a 26-year-old female who felt discomfort in her left ear on February 21, 2024, but chose to ignore it then. She observed an abrupt deviation in her mouth and visited a rural hospital, where she was admitted. Facial asymmetry was observed during the examination, and she was found to have a grade V on the House-Brackmann scale. A near-normal muscle action was initiated by mime therapy, and proprioceptive stimulation was given by facial proprioceptive neuromuscular facilitation along with electrical stimulation. All these approaches benefited the patient in a significant manner.
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  • 文章类型: English Abstract
    Objective:To summarize the clinical characteristics and therapeutic effect of traumatic facial nerve palsy. Methods:Sixty-eight cases of traumatic facial nerve palsy were retrospectively analyzed from January 2015 to May 2023. Results:The median course of disease was 33 days. The facial nerve function of the patients was grade HB-Ⅱin 2 cases, grade HB-Ⅲ in 4 cases, grade HB-Ⅳin 16 cases, grade HB-Ⅴ in 37 cases(38 ears), and grade HB-Ⅵ in 9 cases. 42 cases occurred immediately after injury and 26 cases were delayed. CT examination of temporal bone revealed longitudinal fractures in 51 cases(52 ears) , transverse fractures in 6 cases and mixed fractures in 4 cases. No definite temporal bone fracture was found in the remaining 7 cases. The segments of facial nerve injury in 49 cases(50 ears) were geniculate ganglion and adjacent, in 7 cases were vertical segment, in 7 cases were horizontal segment, in 2 cases were horizontal segment and vertical segment; and the other 3 cases could not be evaluated. Conservative treatment with glucocorticoids was used in 23 ears and surgery was used in 46 ears. Patients were followed up 6-24 months after treatment, including 20 cases of grade HB-Ⅰ, 19 cases of grade HB-Ⅱ, 23 cases(24 ears) of grade HB-Ⅲ, 4 cases of grade HB-Ⅳ, and 1 case of grade HB-Ⅴ.One patient was lost to follow-up. After treatment, the facial nerve function of patients was significantly improved(P<0.05), and there were significant differences between conservative treatment group and surgical treatment group in the course of facial nerve palsy, the ratio of facial palsy immediately after injury, the nerve function before treatment and the nerve function after treatment(P<0.05). There were no significant differences in age, sex, hearing condition, temporal bone fracture, facial nerve injury segment and rate of favorable neurologic outcomes(P>0.05). The comparison of patients with neurodegeneration rate>90% and ≤90% showed that the facial nerve function of patients with neurodegeneration rate>90% before treatment was significantly worse(P<0.05), but there was no significant difference between the facial nerve function after treatment(P>0.05). There was no significant difference in facial nerve function between middle fossa approach group and mastoid approach group(P>0.05). Conclusion:Patients with traumatic facial nerve palsy should be evaluated individually. Patients with mild facial nerve palsy, low neurodegeneration rate and short course of disease can be treated conservatively and followed up closely. Patients with severe facial nerve palsy, high neurodegeneration rate and more than 6 weeks of disease can be actively considered surgery. Good prognosis can be obtained by correct evaluation and treatment.
    目的:总结外伤性面神经麻痹的临床特点及治疗效果。 方法:对2015年1月至2023年5月间68例(69耳)外伤性面神经麻痹病例进行回顾性分析。 结果:就诊时中位病程33 d;就诊时患者的面神经功能HB-Ⅱ级2例,HB-Ⅲ级4例,HB-Ⅳ级16例,HB-Ⅴ级37例(38耳),HB-Ⅵ级9例;42例为伤后即刻发生,26例为迟发性;纵行骨折51例(52耳),横行骨折6例,混合型骨折4例,7例未发现明确颞骨骨折线;损伤节段49例(50耳)为膝状神经节及邻近,7例为垂直段,7例为水平段,2例为水平段、垂直段,3例无法评估。23耳采用以糖皮质激素为主的保守治疗,46耳采用手术治疗。治疗后6~24个月对患者进行随访,HB-Ⅰ级20例,HB-Ⅱ级19例,HB-Ⅲ级23例(24耳),HB-Ⅳ级4例,HB-Ⅴ级1例;失访1例。治疗前后,患者面神经功能明显改善(P<0.05),保守治疗组和手术治疗组患者在面神经麻痹病程、伤后即刻面瘫比率、治疗前面神经功能、治疗后面神经功能差异有统计学意义(P<0.05);年龄、性别、听力情况、颞骨骨折情况、面神经损伤节段、面神经功能良好率差异无统计学意义(P>0.05);对神经变性>90%和≤90%的病例比较显示治疗前神经变性>90%的患者面神经功能明显更差(P<0.05),但两者治疗后的面神经功能差异无统计学意义(P>0.05);颅中窝入路组和乳突入路组治疗前后面神经功能差异无统计学意义(P>0.05)。 结论:外伤性面神经麻痹病例应进行个体化的评估,面神经麻痹程度轻、神经变性比率低、病程短的患者可先行保守治疗并严密随访,对于面神经麻痹程度重、神经变性率高、病程超过6周的患者可积极考虑手术治疗;正确的评估、治疗可获得良好预后。.
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  • 文章类型: Journal Article
    面神经麻痹是腮腺切除术治疗良性唾液腺肿瘤的潜在并发症,需要全面了解其发病率和相关危险因素,以改善患者咨询和术前计划。
    这项单中心回顾性研究旨在评估大学教学医院良性腮腺切除术后面神经麻痹的发生率。
    在3年内,包括160例接受腮腺良性肿瘤手术的患者。数据,包括性,年龄,操作技术,肿瘤病理学,面神经功能,和随访持续时间,是从医疗记录中收集的。排除标准包括既往腮腺手术或术前面神经麻痹的患者。
    该研究显示,良性疾病腮腺切除术后面神经麻痹的发生率为3.75%,没有完全麻痹。多形性腺瘤(50.6%)和Warthin's肿瘤(44.4%)是主要的肿瘤类型。根据获得的协变量,有和没有术后面神经麻痹的组之间没有显着差异。
    我们的研究结果支持部分浅表腮腺切除术和囊外切除术是腮腺良性肿瘤的低风险治疗方法。然而,前瞻性研究有必要阐明面神经麻痹的恢复率和长期后果,有助于改善腮腺手术的手术方法和患者护理。
    UNASSIGNED: Facial nerve palsy is a potential complication of parotidectomy for benign salivary gland tumours, necessitating a comprehensive understanding of its incidence and associated risk factors for improved patient counselling and preoperative planning.
    UNASSIGNED: This single-centre retrospective study aimed to assess the rate of facial nerve palsy following benign parotidectomy at a University Teaching Hospital.
    UNASSIGNED: Over a 3-year period, 160 patients undergoing parotid surgery for benign tumours were included. Data, encompassing sex, age, operation technique, tumour pathology, facial nerve function, and follow-up duration, were collected from medical records. Exclusion criteria comprised patients with prior parotid gland surgery or preoperative facial nerve palsy.
    UNASSIGNED: The study revealed a 3.75% incidence of facial nerve palsy with no total paralysis post-parotidectomy for benign disease. Pleomorphic adenoma (50.6%) and Warthin\'s tumour (44.4%) were the predominant tumour types. No significant differences were noted between groups with and without postoperative facial palsy based on obtained covariates.
    UNASSIGNED: Our findings endorse partial superficial parotidectomy and extracapsular dissection as low-risk treatments for benign parotid tumours. However, prospective studies are warranted to elucidate recovery rates and long-term consequences of facial nerve palsy, contributing to refined surgical approaches and patient care in parotid surgery.
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  • 文章类型: Journal Article
    背景:本研究的目的是报告50岁以下面神经麻痹(FNP)患者眼睑全层植皮的结果。方法:在回顾性研究中,连续案例系列,对八名皮肤收缩的FNP患者(五名女性;中位年龄42岁[范围,17-47])。在大多数情况下,上眼睑植皮结合提上肌凹陷和前板层复位。在所有情况下,下眼睑植皮均与下牵开器退缩相结合。术前和早期(1-3个月)测量功能和美容结果,中级(3-6个月),和晚期(≥12个月)随访。结果:角膜评分在早期随访时有所改善(p=0.03),在晚期随访时仍保持改善(p=0.042)。在后期随访时,轻度闭合的眩眼得到改善(p=0.042)。(p=0.048)。接枝颜色的等级,边缘/皮肤界面,移植后3-6个月,大小改善,随访后期仍有改善(p<0.05)。在后续行动中,4例患者(50%)被建议接受进一步的外科手术.结论:这个小队列的初步结果表明,眼睑植皮是年轻患者优先考虑美容的可行选择。这项技术值得考虑其功能优势。
    Background: The aim of this study is to report outcomes of eyelid full-thickness skin grafting augmentation in facial nerve palsy (FNP) patients younger than 50 years of age. Methods: In a retrospective, consecutive case series, nine eyelid skin grafts performed on eight FNP patients with skin contraction (five females; median age 42 years [range, 17-47]) are presented. In most cases, upper eyelid skin grafting was combined with levator recession and anterior lamellar repositioning. Lower eyelid skin grafting was combined with lower retractors recession in all cases. Functional and cosmetic outcomes were measured preoperatively and at early (1-3 months), intermediate (3-6 months), and late (≥12 months) follow-up. Results: The corneal score improved at early follow-up (p = 0.03) and remained improved at late follow-up (p = 0.042). The gentle closure lagophthalmos was improved at late follow-up (p = 0.042). (p = 0.048). The grades of graft color, edge/skin interface, and size improved at 3-6 months post-grafting and remained improved at late follow-up (p < 0.05). Over the follow-up, four patients (50%) were recommended to have further surgical procedures. Conclusions: The preliminary results from this small cohort suggest that eyelid skin grafting is a viable option for young patients prioritizing cosmesis. This technique warrants consideration for its functional benefits.
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