■我们分析了眨眼的动力学,并使用与临床特征和临床进展相关的眼表干涉仪定义了面神经麻痹(FNP)患者的眨眼指数。
■总共,49名患者参加了这项研究。所有患者均使用眼表干涉仪进行测试,该干涉仪用于测量眨眼模式(总眨眼(TB),部分眨眼率(PBR))和眨眼动态(眨眼时间(BT),盖子关闭时间(LCT),闭合时间(CT),盖子打开时间(LOT),闪烁时间(IBT),关闭速度(CS),andopeningspeed(OS))using600framesrecordedover20s.Thedistanceoflagnoosandmodifiedlapedlesure(IPF),定义为上眼睑的实际移动距离,从IPF中减去眼球的距离,使用ImageJ程序测量。FNP的类型为“特发性”(贝尔麻痹)和“外科”(神经外科手术后)。根据从FNP开始的6个月的持续时间,将患者分为“急性”和“慢性”。根据暴露性角膜病变的严重程度,将临床特征分为轻度或重度-如果需要治疗如tarsorrhy和金板插入,则为“严重”。
■降低MRD1,眉高,在麻痹侧发现改良的IPF和增加的眩眼。LCT较长,CS较长,修改后的CS,麻痹侧的改良OS较短。在急性发作和临床严重的特发性患者中,LCT更长,改良CS更短。临床严重的特发性患者IBT升高。
■分析眨眼模式和眨眼动力学,这项研究提出了眨眼轮廓和动力学中有意义的指标,LCT,并基于修改后的IPF修改CS。与FNP患者的手术类型相比,特发性类型的相关性更高。修饰的CS可以是评估FNP的活性和严重性指标的有用工具。
UNASSIGNED: We analyzed the dynamics of blink and defined the blink index in facial nerve palsy (FNP) patients using an ocular surface interferometer associated with clinical characteristics and clinical progress.
UNASSIGNED: In total, 49 patients were enrolled this study. All patients were tested using an ocular surface interferometer which is used to measure blink patterns (total blink (TB), partial blink rate (PBR)) and blink dynamics (blink time (BT), lid closing time (LCT), closure time (CT), lid opening time (LOT), interblink time (IBT), closing speed (CS), and opening speed (OS)) using 600 frames recorded over 20 s. The distance of lagophthalmos and modified interpalpebral fissure (IPF), which was defined as the actual moving distance of the upper eyelid, subtracting the distance of lagophthalmos from IPF, was measured using the ImageJ program. The types of FNP were \"idiopathic\" (Bell\'s palsy) and \"surgical\" (following the neurosurgery). Patients were classified into \"acute\" and \"chronic\" based on the duration of 6 months from the onset time of FNP. The clinical characteristics were classified into mild or severe according to the severe degree of exposure keratopathy-as \"severe\" if treatment such as tarsorrhaphy and gold plate insertion was required.
UNASSIGNED: Reduced MRD1, brow height, and modified IPF and increased lagophthalmos were noted in the palsy side. LCT was longer and CS, modified CS, and modified OS were shorter in the palsy side. The LCT was longer and the modified CS was shorter in idiopathic patients with acute onset and with clinically severe. IBT was increased in idiopathic patients with clinically severe.
UNASSIGNED: Analyzing the blink patterns and blink dynamics, this study suggests meaningful indicators among blink profiles and dynamics, LCT, and modified CS based on modified IPF. It was more associated in the idiopathic type than in the surgical type of FNP patients. The modified CS can be a useful tool for evaluating the activity and severity indicator of FNP.