我们报告了一例中枢神经系统受累的儿科患者的多系统朗格汉斯细胞组织细胞增生症,强调F-18(FDG)摄取特点的硬脑膜部位的疾病。我们还强调了FDG-PET提供的功能数据作为评估可行性的有用后续工具的优势,因此,先前已知的中枢神经系统病变的治疗反应。识别硬脑膜疾病中FDG摄取的特征模式的效用也适用于诊断不确定性的情况。例如在评估孤立的硬脑膜病变或区分朗格汉斯细胞组织细胞增生症和类似出现的病变如脑膜瘤时。
We report a case of multisystem Langerhans cell histiocytosis in a pediatric patient with central nervous system involvement, highlighting F-18(FDG) uptake characteristics of dural sites of disease. We also highlight the advantages of functional data offered by FDG-PET as a useful follow-up tool to assess viability and, therefore, treatment response of previously known central nervous system lesions. The utility of recognizing characteristic patterns of FDG uptake in dural disease is also applicable in cases of diagnostic uncertainty, such as when evaluating isolated dural lesions or when distinguishing between Langerhans cell histiocytosis and similar appearing lesions such as meningiomas.