真杆菌是一组专性厌氧革兰氏阳性杆菌,被认为是胃肠道菌群的共生菌。由真杆菌介导的菌血症病例很少见。本报告描述了一名82岁女性的愈伤组织真杆菌引起的菌血症病例,该病例具有继发于乙状结肠狭窄的盲肠穿孔病史。结果显示了使用全基因组测序来鉴定病原体的实用性,并强调了在诊断微生物学实践中鉴定厌氧生物和进行抗微生物药敏试验以指导治疗和提高患者预后的重要性。
Eubacterium species are a group of obligated anaerobic gram-positive bacilli that are recognized as commensals of the gastrointestinal tract flora. Cases of bacteremia mediated by Eubacterium are rare. This report describes a case of bacteremia caused by Eubacterium callanderi in an 82-year-old female with a history of a cecal perforation secondary to an obstructing sigmoid stricture. The results showed the utility of using whole genome sequencing to identify the causative agent and underlined the significance to identify anaerobic organisms in diagnostic microbiology practice and to perform antimicrobial susceptibility testing to guide therapy and enhance patient outcomes.