脊髓硬膜外血管脂肪瘤罕见,良性,间充质肿瘤。尚不清楚脊髓硬膜外血管脂肪瘤是真正罕见还是仅仅被低估。在这里,我们评估了脊髓硬膜外血管脂肪瘤患者的人口统计学和临床特征.我们从三个来源收集了脊髓硬膜外血管脂肪瘤患者的数据。首先,我们回顾性分析了2014年1月1日至2023年12月31日在我院诊断为脊髓硬膜外血管脂肪瘤的患者资料.第二,我们对从PubMed检索到的研究进行了文献综述.第三,我们从监测中检索了脊髓血管脂肪瘤患者的详细数据,流行病学,和结束结果(SEER)数据库。我们进行了描述性分析,以调查脊髓硬膜外血管脂肪瘤患者的人口统计学和临床特征。在我们的机构,3例患者被诊断为脊髓硬膜外血管脂肪瘤。此外,我们从文献综述中确定了116例患者,从SEER数据库中确定了15例患者.我们回顾了我们机构的三名患者的治疗史和影像学特征。从文献综述中收集的数据的描述性分析与以前的报告一致。例如,63.0%的病变位于胸部水平。31.9%的病变累及两个椎体,75.6%累及2-4个椎体。患者最常见的症状是背痛,轻瘫,腿部麻木。手术是大多数患者的主要治疗选择,大多数患者获得了完整的肿瘤切除。男性:女性比例为1:1.4,文献中患者的中位年龄为49岁,中位随访时间为24个月.值得注意的是,大多数报告来自亚洲,很少有来自非洲的报告。SEER数据库的结果表明,男女比例为2:1。峰值发病率,这通常是在生命的第五个十年中报道的,没有被观察到。我们介绍了三例脊髓硬膜外血管脂肪瘤,并根据SEER数据库对美国人口进行了文献综述和基于人群的分析,以补充了我们的发现。我们相信我们的研究将提高临床医生对这种罕见肿瘤的理解。
Spinal epidural angiolipomas are rare, benign, mesenchymal tumors. It remains unclear whether spinal epidural angiolipomas are genuinely rare or merely underreported. Herein, we assessed the demographic and clinical characteristics of patients with spinal epidural angiolipoma. We collected data from patients with spinal epidural angiolipoma from three sources. First, we retrospectively analyzed data from patients diagnosed with spinal epidural angiolipoma in our hospital between January 1, 2014, and December 31, 2023. Second, we performed a literature review of studies retrieved from PubMed. Third, we retrieved detailed data of patients with spinal angiolipoma from the Surveillance, Epidemiology, and End Results (SEER) database. We conducted a descriptive analysis to investigate the demographic and clinical characteristics of patients with spinal epidural angiolipoma. At our institution, three patients were diagnosed with spinal epidural angiolipoma. Additionally, we identified 116 patients from the literature review and 15 patients from the SEER database. We reviewed the treatment history and imaging features of the three patients from our institution. The descriptive analysis of the data collected from the literature review was consistent with previous reports. For example, 63.0% of lesions were located at the thoracic level. 31.9% of these lesions involved two vertebral bodies, while 75.6% involved 2-4 vertebral bodies. The most common symptoms experienced by patients were back pain, paraparesis, and numbness in the legs. Surgery was the primary treatment option for most patients, and complete tumor resection was achieved in the majority of patients. The male:female ratio was 1:1.4, the median age at diagnosis for the patients from the literature was 49 years old, and the median follow-up was 24 months. Notably, most of the reports came from Asia and there were few reports from Africa. The findings from the SEER database indicated a male:female ratio of 2:1. The peak incidence, which is typically reported in the fifth decade of life, was not observed. We presented three cases of spinal epidural angiolipoma and supplemented our findings with a literature review and population-based analysis according to the SEER database for the United States population. We believe that our research will enhance clinicians\' comprehension of this uncommon tumor.