目的:子宫内膜异位症是一种炎症性疾病,有不同的表达形式和各种抱怨。子宫内膜瘤,有子宫内膜样内膜的卵巢囊肿,是腹型子宫内膜异位症最常见的表现之一。这些子宫内膜瘤可以,除了医疗,接受手术治疗。手术后,激素治疗仍然经常使用,一般用于子宫内膜异位症的治疗和预防子宫内膜瘤的复发。然而,并非所有女性都希望或可以接受术后激素治疗。对于该小组而言,重要的是要了解子宫内膜瘤手术后卵巢子宫内膜瘤解剖复发的风险。
目的:为了确定手术治疗子宫内膜瘤的复发率,没有术后激素治疗。
方法:我们进行了系统的文献综述和荟萃分析,根据PRISMA指南。MEDLINE,EMBASE,和Cochrane图书馆一直搜索到2023年5月。文献检索仅限于接受手术治疗而未接受术后激素治疗的子宫内膜瘤女性。
■研究设计包括随机对照试验,队列和回顾性研究。为了评估偏见的风险,我们使用了Cochrane系统评价非随机研究中干预措施和偏倚风险手册-干预措施评估工具.
结果:本综述中包括的预后指标是子宫内膜瘤复发。
结果:我们筛选了5367篇文章,其中系统审查了97篇文章,纳入了55篇。其中12项是随机对照试验,11项前瞻性队列研究,和32项回顾性研究。9项随机对照试验(RCT)被指定为低偏倚风险。对于非RCT,只有三项研究的偏倚风险较低.23项研究的数据汇集在荟萃分析中,进行了3、6、12和24个月的随访。这些研究显示复发率为4%,14%,分别为17%和27%。
结论:荟萃分析,术后24个月子宫内膜瘤的加权平均复发率高达27%.
结论:通过这项研究,我们旨在确定未使用激素治疗的女性手术治疗后子宫内膜瘤的复发率。复发率高达27%。
OBJECTIVE: Endometriosis is an inflammatory disease, with different forms of expression and a variety of complaints. An
endometrioma, an ovarian cyst with endometrium-like lining, is one of the most common expressions of abdominal endometriosis. These endometriomas can, in addition to medical treatment, be treated surgically. After surgery, hormonal therapy is still frequently used, for treatment of endometriosis in general and prevention of recurrence of endometriomas specifically. However, not all women want or can receive postoperative hormonal treatment. It is important for this group to know the risk of anatomical recurrence of ovarian
endometrioma after surgery for an
endometrioma.
OBJECTIVE: To determine the recurrence rate for surgically treated endometrioma, without postoperative hormonal treatment.
METHODS: We performed a systematic literature review and meta-analyses, according to the PRISMA guidelines. MEDLINE, EMBASE, and the Cochrane Library were searched until May 2023. The literature search was limited to women with
endometrioma who received surgical treatment without postoperative hormonal treatment.
UNASSIGNED: A distinction was made in study design including randomised controlled trials, cohort and retrospective studies. For assessment of risk of bias, the Cochrane Handbook for Systematic Reviews of Interventions and The Risk of Bias in Non-randomized Studies - of interventions assessment tool were used.
RESULTS: Outcome measure included in this review is
endometrioma recurrence.
RESULTS: We screened 5367 articles, of which ninety-seven articles were systematically reviewed and fifty-five included in this systematic review. Twelve of these were randomised controlled trials, eleven prospective cohort studies, and thirty-two retrospective studies. Nine randomised controlled trials (RCT\'s) were assigned as low risk of bias. For non-RCT\'s, only three studies had low risk of bias. Data of twenty-three studies were pooled in meta-analyses, performed for follow-up periods of 3, 6, 12 and 24 months. These studies showed a recurrence rate of 4%, 14%, 17% and 27% respectively.
CONCLUSIONS: The meta-analysis, at 24 months after surgery the endometrioma recurrence rate showed a weighted average up to 27%.
CONCLUSIONS: With this study, we aimed to determine the recurrence rate of endometrioma after surgical treatment in women without postoperative hormonal treatment use. Recurrence rates were up to 27%.