目的:对道德和传统规则(SMCR)的敏感性得到了双侧大脑网络和社会心理输入的支持,这两者在颞叶癫痫(TLE)中都可能发生改变。这项研究评估了TLE患者的SMCR成分,旨在阐明它们的保存以及与精神病理学和认知方面的联系。
方法:使用SMCR的神经心理学测试对单侧TLE的成年患者和健康对照进行评估,记忆,语言,和执行功能,移情问卷(EQ),和症状检查表-90-R(SCL-90-R)。
结果:SMCR测试项目显示出良好的信度和效度,产生不同于高管的严重性和规则因素,词汇和记忆因素。正确的TLE患者在道德规则识别方面的得分低于对照组,但是这种差异因年龄和性别的重大影响而无效。与语义流畅性和年龄相关的严重程度和规则因素,分别,TLE侧和精神病。然而,这些因素确实可以预测TLE成员资格.
结论:在成人TLE患者中,SMCR测试反映了一个独特的认知领域。传统规则保留得很好,而道德推理只有在不利的人口统计数据共存的情况下,才可能在正确的TLE中受到影响。虽然年龄,TLE侧,语义能力,和精神病患者合作确定SMCR,这种结构域的损害不是TLE的显著特征。
OBJECTIVE: Sensitivity to moral and conventional rules (SMCR) is supported by bilateral brain networks and psychosocial input both of which may be altered in temporal lobe epilepsy (TLE). This study evaluated the components of SMCR in patients with TLE, aiming to clarify their preservation and link to psychopathological and cognitive aspects.
METHODS: Adult patients with unilateral TLE and healthy controls were evaluated using neuropsychological tests for SMCR, memory, language, and executive functions, the
Empathy Questionnaire (EQ), and the Symptom Checklist-90-R (SCL-90-R).
RESULTS: The SMCR test items showed good reliability and validity, yielding the Severity and Rules factors distinct from the Executive, Lexical and Memory factors. Patients with right TLE scored worse in moral rules recognition than controls, but this difference was nullified by a significant influence for age and sex. The Severity and Rules factors related to semantic fluency and age and, respectively, TLE side and psychoticism. However, these factors did predict TLE membership.
CONCLUSIONS: In adult patients with TLE, the SMCR test reflects a distinct cognitive domain. Conventional rules are well-retained, while moral reasoning may be only affected in right TLE if unfavorable demographics coexist. Although age, TLE side, semantic abilities, and psychoticism cooperate to determine SMCR, impairment of such domain is not a distinctive feature of TLE.